Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196716363 . C A CCDS1385.1:NM_000186.3:c.3616Cgt>Agt_NP_000177.2:p.1206R>S Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 ARG A:163 X:1206 139.0 0.618 E -131.5 167.0 139.0 0.618 0.0 HOH
 3.307
 CA
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 ARG B:108 B:1206 159.0 0.707 E -122.9 158.7 104.0 0.462 0.245 A:W5SB08:0.244
 SO4
HOH
 9.429
3.529
 N
CA
 O2
O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 ARG A:108 A:1206 74.0 NA E -140.8 156.8 74.0 NA NA SO4
HOH
 6.956
3.463
 O
CA
 O3
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 ARG A:108 A:1206 69.0 NA E -139.8 154.9 69.0 NA NA HOH
 3.434
 CA
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 ARG D:103 D:1206 189.0 0.84 E -118.0 149.3 189.0 0.84 0.0
ARG E:103 E:1206 67.0 NA -115.3 154.5 NA NA NA
ARG F:103 F:1206 228.0 1.0 -124.2 144.5 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 ARG C:108 C:1206 37.0 NA -122.7 158.5 37.0 NA NA HOH
 2.924
 CB
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 ARG B:104 B:1206 75.0 NA -140.8 168.3 75.0 NA NA HOH
 3.537
 O
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 ARG D:104 D:1206 128.0 0.569 E -137.8 144.1 NA NA NA
ARG E:104 E:1206 144.0 0.64 E -141.8 156.5 NA NA NA
ARG F:104 F:1206 124.0 0.551 E -132.0 147.0 124.0 0.551 0.0 HOH
 3.441
 CA
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 ARG A:104 F:1206 172.0 0.764 E -104.8 155.0 172.0 0.764 0.0
ARG C:104 D:1206 143.0 0.636 E -138.7 147.6 NA NA NA
ARG E:104 E:1206 40.0 NA E -131.1 159.9 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 ARG D:104 D:1206 111.0 NA E -133.9 156.0 NA NA NA
ARG E:104 E:1206 144.0 0.64 E -134.9 158.0 144.0 0.64 0.0 HOH
 3.510
 CA
 O
ARG F:104 NA:NA DO NA DO DO DO NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 ARG A:100 A:1206 207.0 NA E -135.0 151.5 207.0 NA NA HOH
 3.617
 CA
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 ARG A:104 A:1206 96.0 0.427 E -133.9 155.4 96.0 0.427 0.0 HOH
 3.417
 NE
 O
ARG B:104 B:1206 111.0 0.493 E -125.7 159.8 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 ARG D:104 D:1206 149.0 0.662 E -135.7 150.0 149.0 0.662 0.0 HOH
 5.214
 N
 O
ARG E:104 E:1206 127.0 0.564 E -135.0 157.0 NA NA NA
ARG F:104 NA:NA DO NA DO DO DO NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 ARG A:101 A:305 74.0 NA -115.7 168.0 74.0 NA NA
ARG B:101 B:305 56.0 NA E -105.6 158.7 56.0 NA NA
5wtb 2 P08603 100.0 8e-07 X-RAY
 2017-07-19 ARG E:1 E:1206 294.0 1.0 360.0 -39.3 NA NA NA
ARG F:1 F:1206 287.0 1.0 360.0 -18.6 NA NA NA
ARG G:1 G:1206 286.0 1.0 360.0 -38.2 NA NA NA
ARG H:1 H:1206 285.0 1.0 360.0 11.7 49.0 0.218 0.782 A:Q932F7:1.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 ARG A:1206 A:1206 153.0 0.68 E -130.0 154.5