Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196716375 . C A CCDS1385.1:NM_000186.3:c.3628Cgt>Agt_NP_000177.2:p.1210R>S Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 ARG A:167 X:1210 242.0 1.0 T -108.3 17.0 242.0 1.0 0.0 HOH
 4.859
 O
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 ARG B:112 B:1210 159.0 0.707 -60.9 152.1 159.0 0.707 0.0 EDO
SO4
HOH
 7.117
2.710
3.805
 O
NH1
C
 O2
O2
O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 ARG A:112 A:1210 110.0 NA T 69.7 -3.4 110.0 NA NA HOH
 4.680
 O
 O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 ARG A:112 A:1210 111.0 NA T 75.6 0.8 111.0 NA NA HOH
 3.695
 O
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 ARG D:107 D:1210 192.0 0.853 -64.9 155.6 192.0 0.853 0.0
ARG E:107 NA:NA DO NA DO DO DO NA NA NA
ARG F:107 NA:NA DO NA DO DO DO NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 ARG C:112 C:1210 96.0 NA T -79.2 5.5 96.0 NA NA HOH
 5.136
 N
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 ARG B:108 B:1210 82.0 NA T -66.4 -29.6 82.0 NA NA HOH
 5.306
 N
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 ARG D:108 D:1210 233.0 1.0 T -107.7 58.0 NA NA NA
ARG E:108 E:1210 240.0 1.0 T -116.8 29.7 NA NA NA
ARG F:108 F:1210 185.0 0.822 -57.5 160.6 185.0 0.822 0.0 HOH
 2.843
 N
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 ARG A:108 F:1210 47.0 NA -58.0 166.3 47.0 NA NA
ARG C:108 D:1210 242.0 1.0 T -108.7 56.2 NA NA NA
ARG E:108 E:1210 246.0 1.0 T -96.8 30.0 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 ARG D:108 D:1210 239.0 1.0 T -110.4 48.0 NA NA NA
ARG E:108 E:1210 244.0 1.0 T -96.9 14.6 244.0 1.0 0.0 HOH
 4.950
 O
 O
ARG F:108 NA:NA DO NA DO DO DO NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 ARG A:104 A:1210 239.0 NA T 68.8 0.9 239.0 NA NA HOH
 4.740
 O
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 ARG A:108 A:1210 162.0 0.72 T -106.3 11.4 162.0 0.72 0.0 HOH
 2.808
 NH2
 O
ARG B:108 B:1210 207.0 0.92 T -96.5 3.4 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 ARG D:108 D:1210 218.0 0.969 T -103.3 63.2 125.0 0.556 0.413 A:P01024:0.413
 HOH
 3.336
 CB
 O
ARG E:108 E:1210 246.0 1.0 T 70.0 9.4 NA NA NA
ARG F:108 NA:NA DO NA DO DO DO NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 ARG A:105 A:309 150.0 NA T -139.7 95.2 150.0 NA NA
ARG B:105 B:309 138.0 NA S -74.0 17.6 138.0 NA NA
5wtb 2 P08603 100.0 8e-07 X-RAY
 2017-07-19 ARG E:5 E:1210 213.0 0.947 -131.5 172.3 NA NA NA
ARG F:5 F:1210 152.0 0.676 -173.2 145.0 NA NA NA
ARG G:5 G:1210 159.0 0.707 -162.4 170.9 NA NA NA
ARG H:5 H:1210 211.0 0.938 -127.6 170.5 82.0 0.364 0.574 A:Q932F7:0.573

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 ARG A:1210 A:1210 181.0 0.804 T -96.4 5.1