Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 196716423 | . | C | A | CCDS1385.1:NM_000186.3:c.3676Cca>Aca_NP_000177.2:p.1226P>T | Homo sapiens complement factor H (CFH), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3sw0 | 1 | P08603 | 100.0 | 2e-126 |
X-RAY |
2012-03-14 | PRO | A:183 | X:1226 | 0.0 | 0.0 | -84.7 | 164.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.566 |
CA |
O |
|||
| 6zh1 | 2 | P08603 | 100.0 | 4e-83 |
X-RAY |
2022-01-12 | PRO | B:128 | B:1226 | 0.0 | 0.0 | -72.8 | 167.4 | 0.0 | 0.0 | 0.0 |
EDO SO4 HOH |
8.897 6.104 3.782 |
CG CA CA |
O2 O1 O |
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| 3kxv | 1 | P08603 | 99.22 | 5e-83 |
X-RAY |
2010-05-19 | PRO | A:128 | A:1226 | 0.0 | 0.0 | -69.2 | 157.0 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
8.490 3.719 |
CD CA |
O4 O |
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| 3kzj | 1 | P08603 | 99.22 | 6e-83 |
X-RAY |
2010-05-19 | PRO | A:128 | A:1226 | 0.0 | 0.0 | -71.8 | 158.5 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
8.602 3.705 |
CD CA |
O4 O |
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| 5nbq | 2 | P08603 | 100.0 | 3e-82 |
X-RAY |
2017-12-06 | PRO | D:123 | D:1226 | 2.0 | 0.014 | -79.1 | 166.0 | 2.0 | 0.014 | 0.0 | |||||||
| PRO | E:123 | E:1226 | 3.0 | 0.021 | -66.5 | 139.5 | NA | NA | NA | ||||||||||||||
| PRO | F:123 | F:1226 | 3.0 | 0.021 | -70.6 | 152.1 | NA | NA | NA | ||||||||||||||
| 2xqw | 2 | P08603 | 98.45 | 5e-82 |
X-RAY |
2011-02-02 | PRO | C:128 | C:1226 | 0.0 | 0.0 | -60.9 | 145.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.828 |
C |
O |
|||
| 4j38 | 2 | P08603 | 98.45 | 6e-82 |
X-RAY |
2013-05-15 | PRO | B:124 | B:1226 | 4.0 | 0.028 | -80.1 | 156.5 | 4.0 | 0.028 | 0.0 |
HOH |
7.699 |
CG |
O |
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| 3oxu | 2 | Q14006 | 100.0 | 4e-81 |
X-RAY |
2011-02-16 | PRO | D:124 | D:1226 | 0.0 | 0.0 | -76.3 | 162.4 | NA | NA | NA | |||||||
| PRO | E:124 | E:1226 | 0.0 | 0.0 | -75.2 | 158.4 | NA | NA | NA | ||||||||||||||
| PRO | F:124 | F:1226 | 0.0 | 0.0 | -71.7 | 168.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.140 |
N |
O |
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| 4ont | 1 | P08603 | 100.0 | 4e-81 |
X-RAY |
2014-11-26 | PRO | A:124 | F:1226 | 0.0 | 0.0 | -70.6 | 144.9 | 0.0 | 0.0 | 0.0 | |||||||
| PRO | C:124 | D:1226 | 0.0 | 0.0 | -72.0 | 161.0 | NA | NA | NA | ||||||||||||||
| PRO | E:124 | E:1226 | 0.0 | 0.0 | -60.8 | 161.0 | NA | NA | NA | ||||||||||||||
| 4zh1 | 2 | P08603 | 100.0 | 4e-81 |
X-RAY |
2016-01-13 | PRO | D:124 | D:1226 | 0.0 | 0.0 | -73.5 | 160.8 | NA | NA | NA | |||||||
| PRO | E:124 | E:1226 | 0.0 | 0.0 | -70.8 | 160.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.704 |
CB |
O |
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| PRO | F:124 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 2g7i | 1 | P08603 | 100.0 | 6e-81 |
X-RAY |
2006-05-23 | PRO | A:120 | A:1226 | 0.0 | 0.0 | -78.0 | 161.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.428 |
CA |
O |
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| 3r62 | 1 | P08603 | 99.2 | 3e-80 |
X-RAY |
2011-06-29 | PRO | A:124 | A:1226 | 0.0 | 0.0 | -76.0 | 166.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.514 |
C |
O |
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| PRO | B:124 | B:1226 | 0.0 | 0.0 | -82.8 | 176.5 | NA | NA | NA | ||||||||||||||
| 3rj3 | 2 | Q03591 | 99.2 | 3e-80 |
X-RAY |
2012-03-14 | PRO | D:124 | D:1226 | 0.0 | 0.0 | -75.5 | 157.1 | 0.0 | 0.0 | 0.0 |
HOH |
3.503 |
CA |
O |
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| PRO | E:124 | E:1226 | 0.0 | 0.0 | -76.3 | 154.2 | NA | NA | NA | ||||||||||||||
| PRO | F:124 | F:1226 | 29.0 | 0.2 | -70.2 | 136.6 | NA | NA | NA | ||||||||||||||
| 4muc | 1 | Q03591 | 98.4 | 1e-79 |
X-RAY |
2015-02-18 | PRO | A:121 | A:325 | 0.0 | 0.0 | -81.4 | 164.2 | 0.0 | 0.0 | 0.0 | |||||||
| PRO | B:121 | B:325 | 0.0 | 0.0 | -93.1 | 177.6 | 0.0 | 0.0 | 0.0 |
SO4 |
9.212 |
CD |
O4 |
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| 5wtb | 2 | P08603 | 100.0 | 8e-07 |
X-RAY |
2017-07-19 | PRO | E:21 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| PRO | F:21 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| PRO | G:21 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| PRO | H:21 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p08603-f1 | 1 | P08603 | 99.92 | 0.0 | PRO | A:1226 | A:1226 | 0.0 | 0.0 | -74.5 | 145.1 | ||