Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196801046 . T A CCDS1386.1:NM_002113.2:c.910Tat>Aat_NP_002104.2:p.304Y>N Homo sapiens complement factor H related 1 (CFHR1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 97.31 3e-134 X-RAY
 2012-03-14 TYR A:162 X:1205 73.0 0.317 -118.6 157.6 73.0 0.317 0.0 HOH
 3.402
 CE2
 O
6zh1 2 P08603 98.44 2e-89 X-RAY
 2022-01-12 TYR B:107 B:1205 59.0 0.257 E -123.7 149.5 14.0 0.061 0.196 A:W5SB08:0.196
 EDO
SO4
HOH
 6.431
2.770
3.397
 CE1
OH
CE1
 C2
O2
O
3kxv 1 P08603 97.67 2e-89 X-RAY
 2010-05-19 TYR A:107 A:1205 78.0 0.339 -124.6 161.3 78.0 0.339 0.0 SO4
HOH
 3.229
4.548
 CE2
O
 O3
O
3kzj 1 P08603 97.67 2e-89 X-RAY
 2010-05-19 TYR A:107 A:1205 79.0 0.343 -126.2 161.1 79.0 0.343 0.0 HOH
 3.121
 O
 O
4muc 1 Q03591 100.0 1e-88 X-RAY
 2015-02-18 TYR A:100 A:304 127.0 0.552 -81.6 160.7 127.0 0.552 0.0
TYR B:100 B:304 87.0 0.378 -126.2 143.1 87.0 0.378 0.0
5nbq 2 P08603 98.43 1e-88 X-RAY
 2017-12-06 TYR D:102 D:1205 82.0 0.357 -100.4 152.8 82.0 0.357 0.0
TYR E:102 E:1205 104.0 0.452 -94.1 147.4 NA NA NA
TYR F:102 F:1205 104.0 0.452 -138.3 135.3 NA NA NA
2xqw 2 P08603 96.9 2e-88 X-RAY
 2011-02-02 TYR C:107 C:1205 57.0 0.248 -131.5 149.5 23.0 0.1 0.148 B:P01024:0.148
 HOH
 4.303
 CE1
 O
4j38 2 P08603 96.9 4e-88 X-RAY
 2013-05-15 TYR B:103 B:1205 121.0 0.526 -102.5 171.3 121.0 0.526 0.0 HOH
 3.926
 CB
 O
3rj3 2 Q03591 99.2 4e-88 X-RAY
 2012-03-14 TYR D:103 D:1205 70.0 0.304 E -130.9 158.7 40.0 0.174 0.13 A:P01024:0.13
 HOH
 2.392
 OH
 O
TYR E:103 E:1205 54.0 0.235 E -116.5 157.8 NA NA NA
TYR F:103 NA:NA DO NA DO DO DO NA NA NA
3oxu 2 Q14006 98.4 3e-87 X-RAY
 2011-02-16 TYR D:103 D:1205 71.0 0.309 -129.6 159.9 NA NA NA
TYR E:103 E:1205 91.0 0.396 -119.0 161.5 NA NA NA
TYR F:103 F:1205 60.0 0.261 E -127.8 161.8 60.0 0.261 0.0 HOH
 3.329
 N
 O
4ont 1 P08603 98.4 3e-87 X-RAY
 2014-11-26 TYR A:103 F:1205 53.0 0.23 -124.0 166.9 53.0 0.23 0.0
TYR C:103 D:1205 68.0 0.296 E -130.6 161.3 NA NA NA
TYR E:103 E:1205 68.0 0.296 E -109.3 154.6 NA NA NA
4zh1 2 P08603 98.4 3e-87 X-RAY
 2016-01-13 TYR D:103 D:1205 78.0 0.339 E -122.4 155.3 NA NA NA
TYR E:103 E:1205 76.0 0.33 E -112.2 153.4 76.0 0.33 0.0 HOH
 3.979
 N
 O
TYR F:103 NA:NA DO NA DO DO DO NA NA NA
2g7i 1 P08603 98.4 5e-87 X-RAY
 2006-05-23 TYR A:99 A:1205 72.0 0.313 -133.1 160.5 72.0 0.313 0.0 HOH
 3.207
 OH
 O
3r62 1 P08603 97.6 2e-86 X-RAY
 2011-06-29 TYR A:103 A:1205 39.0 0.17 E -122.7 158.4 39.0 0.17 0.0 HOH
 3.817
 N
 O
TYR B:103 B:1205 64.0 0.278 E -121.7 156.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q03591-f1 1 Q03591 100.0 0.0 TYR A:304 A:304 67.0 0.291 E -115.8 162.9