Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 202566033 | . | A | C | CCDS1427.1:NM_001136504.1:c.1112aTa>aGa_NP_001129976.1:p.371I>R | Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5w5c | 6 | P21707 | 86.52 | 1e-174 |
X-RAY |
2017-08-23 | ILE | F:234 | F:373 | 14.0 | 0.08 | E | -84.4 | -46.3 | 14.0 | 0.08 | 0.0 |
GOL HOH |
8.773 2.646 |
CD1 O |
C1 O |
||
| 2r83 | 1 | P21579 | 86.17 | 5e-174 |
X-RAY |
2008-02-12 | ILE | A:236 | A:373 | 11.0 | 0.063 | E | -97.8 | -24.6 | 11.0 | 0.063 | 0.0 |
HOH |
8.825 |
CG2 |
O |
||
| ILE | B:236 | B:373 | 11.0 | 0.063 | E | -96.8 | -25.7 | 11.0 | 0.063 | 0.0 |
HOH |
9.408 |
CG2 |
O |
|||||||||
| 5ccg | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | ILE | E:233 | E:373 | 13.0 | 0.074 | E | -75.2 | -52.7 | 13.0 | 0.074 | 0.0 |
CA CA |
8.671 7.741 |
CD1 CG1 |
CA CA |
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| ILE | F:233 | F:373 | 23.0 | 0.131 | E | -77.5 | -52.8 | 23.0 | 0.131 | 0.0 |
CA |
9.726 |
CD1 |
CA |
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| ILE | K:233 | K:373 | 7.0 | 0.04 | E | -76.9 | -52.4 | NA | NA | NA | |||||||||||||
| 5cch | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | ILE | E:233 | E:373 | 18.0 | 0.103 | E | -80.1 | -50.7 | 18.0 | 0.103 | 0.0 |
CA CA |
8.314 7.978 |
CD1 CG1 |
CA CA |
||
| ILE | F:233 | F:373 | 21.0 | 0.12 | E | -82.1 | -51.6 | 21.0 | 0.12 | 0.0 |
CA CA |
8.993 7.528 |
CD1 CD1 |
CA CA |
|||||||||
| 5cci | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | ILE | E:233 | E:373 | 11.0 | 0.063 | E | -85.3 | -57.5 | 11.0 | 0.063 | 0.0 |
MG |
8.129 |
CD1 |
MG |
||
| ILE | F:233 | F:373 | 45.0 | 0.257 | -93.4 | -60.8 | 45.0 | 0.257 | 0.0 |
MG |
7.042 |
CD1 |
MG |
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| 6mti | 2 | P21707 | 86.79 | 6e-174 |
EM |
2019-04-24 | ILE | B:233 | 2:654 | 11.0 | 0.063 | E | -85.3 | -57.6 | 11.0 | 0.063 | 0.0 |
MG |
8.129 |
CD1 |
MG |
||
| ILE | C:233 | 3:654 | 11.0 | 0.063 | E | -85.3 | -57.4 | 11.0 | 0.063 | 0.0 |
MG |
8.130 |
CD1 |
MG |
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| ILE | D:233 | 4:654 | 11.0 | 0.063 | E | -85.3 | -57.4 | 11.0 | 0.063 | 0.0 |
MG |
8.129 |
CD1 |
MG |
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| ILE | E:233 | 5:654 | 11.0 | 0.063 | E | -85.3 | -57.6 | 11.0 | 0.063 | 0.0 |
MG |
8.128 |
CD1 |
MG |
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| 5kj7 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | ILE | E:233 | E:373 | 13.0 | 0.074 | E | -78.4 | -56.2 | 13.0 | 0.074 | 0.0 |
CA CA |
8.731 7.932 |
CD1 CG1 |
CA CA |
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| ILE | F:233 | F:373 | 21.0 | 0.12 | E | -87.4 | -49.9 | NA | NA | NA | |||||||||||||
| ILE | K:233 | K:373 | 9.0 | 0.051 | E | -80.1 | -55.3 | NA | NA | NA | |||||||||||||
| 5kj8 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | ILE | E:233 | E:373 | 14.0 | 0.08 | E | -83.8 | -50.1 | 14.0 | 0.08 | 0.0 |
CA CA |
7.431 7.296 |
CD1 CG1 |
CA CA |
||
| ILE | F:233 | F:373 | 21.0 | 0.12 | E | -82.8 | -48.7 | NA | NA | NA | |||||||||||||
| ILE | K:233 | K:373 | 6.0 | 0.034 | E | -83.4 | -49.0 | NA | NA | NA | |||||||||||||
| 6tz3 | 1 | P21579 | 84.71 | 1e-84 |
X-RAY |
2020-05-13 | ILE | A:109 | A:374 | 8.0 | 0.046 | E | -79.4 | -51.8 | 8.0 | 0.046 | 0.0 |
HOH |
2.788 |
O |
O |
||
| 2yoa | 1 | P21707 | 87.42 | 2e-84 |
X-RAY |
2013-03-20 | ILE | A:104 | A:373 | 8.0 | 0.046 | E | -87.9 | -52.4 | 8.0 | 0.046 | 0.0 |
CA CA HOH |
8.360 8.139 3.081 |
CD1 CG1 O |
CA CA O |
||
| ILE | B:104 | B:373 | 8.0 | 0.046 | E | -89.2 | -52.9 | NA | NA | NA | |||||||||||||
| 5t0s | 1 | P46096 | 87.42 | 2e-84 |
X-RAY |
2017-06-14 | ILE | A:103 | A:373 | 7.0 | 0.04 | E | -86.8 | -48.8 | 7.0 | 0.04 | 0.0 |
CD HOH |
7.946 2.704 |
CD1 O |
CD O |
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| 2lha | 1 | P21579 | 87.42 | 3e-84 |
NMR |
2012-05-02 | ILE | A:104 | A:373 | 12.0 | 0.069 | -106.7 | 179.5 | 12.0 | 0.069 | 0.0 | |||||||
| 5w5d | 6 | P21707 | 87.42 | 3e-84 |
X-RAY |
2017-08-23 | ILE | F:104 | F:373 | 12.0 | 0.069 | E | -79.4 | -53.0 | 12.0 | 0.069 | 0.0 |
HOH |
5.604 |
N |
O |
||
| 6u4u | 1 | P21579 | 84.71 | 4e-84 |
X-RAY |
2020-05-13 | ILE | A:109 | A:374 | 7.0 | 0.04 | E | -78.2 | -51.8 | 7.0 | 0.04 | 0.0 |
SO4 SO4 HOH |
9.918 9.625 2.714 |
H HG21 HD11 |
O1 O4 O |
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| 1tjm | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-28 | ILE | A:111 | A:373 | 7.0 | 0.04 | E | -76.0 | -54.5 | 7.0 | 0.04 | 0.0 |
SR HOH |
7.389 1.980 |
HD12 HD12 |
SR H2 |
||
| 1tjx | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-11-23 | ILE | A:111 | A:373 | 6.0 | 0.034 | E | -78.5 | -53.9 | 6.0 | 0.034 | 0.0 |
CA CA HOH |
7.807 7.568 2.041 |
HD12 HD12 HD12 |
CA CA H2 |
||
| 1uov | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-09 | ILE | A:111 | A:373 | 7.0 | 0.04 | E | -77.7 | -51.8 | 7.0 | 0.04 | 0.0 |
CA CA HOH |
8.343 8.460 2.770 |
CG1 CD1 O |
CA CA O |
||
| 1uow | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-16 | ILE | A:111 | A:373 | 6.0 | 0.034 | E | -78.7 | -53.8 | 6.0 | 0.034 | 0.0 |
CA CA HOH |
8.411 8.527 2.887 |
CG1 CD1 O |
CA CA O |
||
| 6u4w | 1 | P21579 | 84.08 | 7e-84 |
X-RAY |
2020-05-13 | ILE | A:109 | A:374 | 7.0 | 0.04 | E | -76.6 | -48.9 | 7.0 | 0.04 | 0.0 |
SO4 SO4 HOH |
9.980 9.721 2.579 |
HD13 H HD11 |
O4 O2 O |
||
| 2n1t | 5 | P21579 | 85.81 | 7e-84 |
NMR |
2015-06-03 | ILE | E:111 | E:373 | 9.0 | 0.051 | E | -68.5 | -43.5 | 9.0 | 0.051 | 0.0 | ||||||
| 4v11 | 1 | P21579 | 87.33 | 1e-83 |
X-RAY |
2015-02-25 | ILE | A:102 | A:374 | 5.0 | 0.029 | E | -83.9 | -45.5 | 5.0 | 0.029 | 0.0 |
CA CA HOH |
8.299 8.116 3.130 |
CD1 CG1 O |
CA CA O |
||
| 5vff | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | ILE | A:103 | A:373 | 7.0 | 0.04 | E | -83.1 | -50.8 | 7.0 | 0.04 | 0.0 |
PB HOH |
8.033 2.782 |
CD1 O |
PB O |
||
| 5vfg | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | ILE | A:103 | A:373 | 7.0 | 0.04 | E | -81.7 | -55.3 | 7.0 | 0.04 | 0.0 |
PB HOH |
8.374 2.699 |
CD1 O |
PB O |
||
| 6u41 | 1 | P21579 | 84.08 | 2e-83 |
X-RAY |
2020-05-13 | ILE | A:109 | A:374 | 6.0 | 0.034 | E | -76.1 | -47.0 | 6.0 | 0.034 | 0.0 |
SO4 HOH |
9.739 2.602 |
H HD11 |
O2 O |
||
| 5ccj | 1 | P21707 | 84.11 | 8e-80 |
X-RAY |
2015-08-12 | ILE | A:104 | A:373 | 8.0 | 0.046 | E | -91.4 | -49.5 | 8.0 | 0.046 | 0.0 |
SO4 SO4 HOH |
9.982 8.094 3.011 |
N O O |
O1 O1 O |
||
| ILE | B:104 | B:373 | 8.0 | 0.046 | E | -82.4 | -49.4 | NA | NA | NA | |||||||||||||
| ILE | C:104 | C:373 | 8.0 | 0.046 | E | -82.0 | -51.7 | NA | NA | NA | |||||||||||||
| ILE | D:104 | D:373 | 7.0 | 0.04 | E | -79.6 | -47.8 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q8n9i0-f1 | 1 | Q8N9I0 | 100.0 | 0.0 | ILE | A:371 | A:371 | 5.0 | 0.029 | E | -74.3 | -44.8 | |