Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 202566051 | . | A | C | CCDS1427.1:NM_001136504.1:c.1094cTg>cGg_NP_001129976.1:p.365L>R | Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5w5c | 6 | P21707 | 86.52 | 1e-174 |
X-RAY |
2017-08-23 | ILE | F:228 | F:367 | 96.0 | 0.549 | T | -56.9 | 140.6 | 96.0 | 0.549 | 0.0 |
HOH |
3.475 |
CA |
O |
||
| 2r83 | 1 | P21579 | 86.17 | 5e-174 |
X-RAY |
2008-02-12 | ILE | A:230 | A:367 | 155.0 | 0.886 | S | -95.9 | 84.1 | 155.0 | 0.886 | 0.0 |
HOH |
5.588 |
N |
O |
||
| ILE | B:230 | B:367 | 156.0 | 0.891 | S | -96.2 | 83.7 | 156.0 | 0.891 | 0.0 |
HOH |
7.216 |
N |
O |
|||||||||
| 5ccg | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | ILE | E:227 | E:367 | 165.0 | 0.943 | S | -124.1 | 129.1 | 165.0 | 0.943 | 0.0 |
CA CA |
7.229 7.647 |
N O |
CA CA |
||
| ILE | F:227 | F:367 | 68.0 | NA | S | -123.3 | 128.4 | 68.0 | NA | NA |
CA |
6.983 |
N |
CA |
|||||||||
| ILE | K:227 | K:367 | 164.0 | 0.937 | S | -124.4 | 129.8 | NA | NA | NA | |||||||||||||
| 5cch | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | ILE | E:227 | E:367 | 151.0 | 0.863 | S | -107.8 | 132.1 | 151.0 | 0.863 | 0.0 |
CA CA |
8.079 7.775 |
O O |
CA CA |
||
| ILE | F:227 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 5cci | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | ILE | E:227 | E:367 | 66.0 | NA | S | -88.8 | 123.1 | 66.0 | NA | NA |
MG |
8.659 |
N |
MG |
||
| ILE | F:227 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6mti | 2 | P21707 | 86.79 | 6e-174 |
EM |
2019-04-24 | ILE | B:227 | 2:648 | 66.0 | NA | S | -88.6 | 123.1 | 66.0 | NA | NA |
MG |
8.659 |
N |
MG |
||
| ILE | C:227 | 3:648 | 67.0 | NA | S | -88.8 | 123.2 | 67.0 | NA | NA |
MG |
8.658 |
N |
MG |
|||||||||
| ILE | D:227 | 4:648 | 67.0 | NA | S | -88.8 | 123.1 | 67.0 | NA | NA |
MG |
8.659 |
N |
MG |
|||||||||
| ILE | E:227 | 5:648 | 67.0 | NA | S | -88.7 | 123.1 | 67.0 | NA | NA |
MG |
8.659 |
N |
MG |
|||||||||
| 5kj7 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | ILE | E:227 | E:367 | 163.0 | 0.931 | S | -126.6 | 132.6 | 163.0 | 0.931 | 0.0 |
CA CA |
7.338 7.551 |
N O |
CA CA |
||
| ILE | F:227 | F:367 | 69.0 | NA | S | -116.1 | 131.4 | NA | NA | NA | |||||||||||||
| ILE | K:227 | K:367 | 164.0 | 0.937 | S | -128.4 | 134.3 | NA | NA | NA | |||||||||||||
| 5kj8 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | ILE | E:227 | E:367 | 166.0 | 0.949 | S | -122.3 | 128.6 | 166.0 | 0.949 | 0.0 |
CA CA |
8.104 7.940 |
N O |
CA CA |
||
| ILE | F:227 | F:367 | 68.0 | NA | S | -122.3 | 129.3 | NA | NA | NA | |||||||||||||
| ILE | K:227 | K:367 | 166.0 | 0.949 | S | -122.8 | 130.7 | NA | NA | NA | |||||||||||||
| 6tz3 | 1 | P21579 | 84.71 | 1e-84 |
X-RAY |
2020-05-13 | ILE | A:103 | A:368 | 136.0 | 0.777 | S | -128.0 | 131.0 | 136.0 | 0.777 | 0.0 |
SO4 HOH |
9.199 2.402 |
C H |
O4 O |
||
| 2yoa | 1 | P21707 | 87.42 | 2e-84 |
X-RAY |
2013-03-20 | ILE | A:98 | A:367 | 155.0 | 0.886 | S | -124.0 | 131.8 | 155.0 | 0.886 | 0.0 |
CA CA CA SEP CA HOH |
7.643 6.952 4.614 4.682 8.304 2.608 |
O O O N N O |
CA CA CA OXT CA O |
||
| ILE | B:98 | B:367 | 156.0 | 0.891 | S | -123.5 | 129.6 | NA | NA | NA | |||||||||||||
| 5t0s | 1 | P46096 | 87.42 | 2e-84 |
X-RAY |
2017-06-14 | ILE | A:97 | A:367 | 151.0 | 0.863 | T | -56.3 | 133.5 | 151.0 | 0.863 | 0.0 |
CD HOH |
9.848 3.805 |
N CA |
CD O |
||
| 2lha | 1 | P21579 | 87.42 | 3e-84 |
NMR |
2012-05-02 | ILE | A:98 | A:367 | 130.0 | 0.743 | G | 64.0 | 35.3 | 130.0 | 0.743 | 0.0 |
IHP |
2.857 |
HG21 |
O22 |
||
| 5w5d | 6 | P21707 | 87.42 | 3e-84 |
X-RAY |
2017-08-23 | ILE | F:98 | F:367 | 96.0 | 0.549 | T | -59.1 | 138.9 | 96.0 | 0.549 | 0.0 |
HOH |
3.417 |
CB |
O |
||
| 6u4u | 1 | P21579 | 84.71 | 4e-84 |
X-RAY |
2020-05-13 | THR | A:103 | A:368 | 120.0 | 0.857 | S | -130.8 | 130.1 | 120.0 | 0.857 | 0.0 |
SO4 HOH |
9.540 2.295 |
C H |
O4 O |
||
| 1tjm | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-28 | ILE | A:105 | A:367 | 126.0 | 0.72 | S | -127.5 | 139.1 | 126.0 | 0.72 | 0.0 |
SR HOH |
7.891 2.159 |
H O |
SR H2 |
||
| 1tjx | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-11-23 | ILE | A:105 | A:367 | 152.0 | 0.869 | S | -127.6 | 132.3 | 152.0 | 0.869 | 0.0 |
CA CA HOH |
7.193 7.511 1.785 |
O H H |
CA CA H2 |
||
| 1uov | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-09 | ILE | A:105 | A:367 | 148.0 | 0.846 | S | -121.7 | 130.1 | 148.0 | 0.846 | 0.0 |
CA CA HOH |
7.045 7.730 2.402 |
O O O |
CA CA O |
||
| 1uow | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-16 | ILE | A:105 | A:367 | 152.0 | 0.869 | S | -128.0 | 132.0 | 152.0 | 0.869 | 0.0 |
CA CA HOH |
7.198 7.915 2.657 |
O O O |
CA CA O |
||
| 6u4w | 1 | P21579 | 84.08 | 7e-84 |
X-RAY |
2020-05-13 | ILE | A:103 | A:368 | 135.0 | 0.771 | S | -128.7 | 130.7 | 135.0 | 0.771 | 0.0 |
SO4 HOH |
9.616 2.416 |
C H |
O1 O |
||
| 2n1t | 5 | P21579 | 85.81 | 7e-84 |
NMR |
2015-06-03 | ILE | E:105 | E:367 | 143.0 | 0.817 | S | -62.6 | -36.4 | 133.0 | 0.76 | 0.057 |
B:P32851:0.057 |
|||||
| 4v11 | 1 | P21579 | 87.33 | 1e-83 |
X-RAY |
2015-02-25 | ILE | A:96 | A:368 | 146.0 | 0.834 | S | -117.3 | 120.2 | 146.0 | 0.834 | 0.0 |
CA CA HOH |
7.198 6.109 2.890 |
O O O |
CA CA O |
||
| 5vff | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | ILE | A:97 | A:367 | 147.0 | 0.84 | S | -111.2 | 98.1 | 147.0 | 0.84 | 0.0 |
PB HOH |
7.900 3.332 |
N C |
PB O |
||
| 5vfg | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | ILE | A:97 | A:367 | 147.0 | 0.84 | S | -114.2 | 115.7 | 147.0 | 0.84 | 0.0 |
PB HOH |
7.782 2.884 |
O N |
PB O |
||
| 6u41 | 1 | P21579 | 84.08 | 2e-83 |
X-RAY |
2020-05-13 | ILE | A:103 | A:368 | 148.0 | 0.846 | S | -105.9 | 138.1 | 148.0 | 0.846 | 0.0 |
SO4 HOH |
8.929 2.562 |
C O |
O4 O |
||
| 5ccj | 1 | P21707 | 84.11 | 8e-80 |
X-RAY |
2015-08-12 | ILE | A:98 | A:367 | 163.0 | 0.931 | T | -101.9 | 7.2 | 163.0 | 0.931 | 0.0 |
HOH |
3.153 |
N |
O |
||
| ILE | B:98 | B:367 | 148.0 | 0.846 | S | -122.2 | 140.2 | NA | NA | NA | |||||||||||||
| ILE | C:98 | C:367 | 139.0 | 0.794 | S | -91.3 | 103.5 | NA | NA | NA | |||||||||||||
| ILE | D:98 | D:367 | 144.0 | 0.823 | S | -97.2 | 129.3 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q8n9i0-f1 | 1 | Q8N9I0 | 100.0 | 0.0 | LEU | A:365 | A:365 | 165.0 | 0.971 | S | -128.3 | 122.4 | |