Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 202566070 | . | C | A | CCDS1427.1:NM_001136504.1:c.1075Gtg>Ttg_NP_001129976.1:p.359V>L | Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5w5c | 6 | P21707 | 86.52 | 1e-174 |
X-RAY |
2017-08-23 | VAL | F:222 | F:361 | 0.0 | 0.0 | E | -109.3 | 126.1 | 0.0 | 0.0 | 0.0 |
HOH |
6.229 |
N |
O |
||
| 2r83 | 1 | P21579 | 86.17 | 5e-174 |
X-RAY |
2008-02-12 | VAL | A:224 | A:361 | 0.0 | 0.0 | E | -109.3 | 121.1 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | B:224 | B:361 | 0.0 | 0.0 | E | -109.2 | 121.6 | 0.0 | 0.0 | 0.0 |
HOH |
9.787 |
N |
O |
|||||||||
| 5ccg | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | VAL | E:221 | E:361 | 0.0 | 0.0 | E | -93.8 | 122.5 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | F:221 | F:361 | 1.0 | 0.006 | E | -93.0 | 123.1 | 1.0 | 0.006 | 0.0 | |||||||||||||
| VAL | K:221 | K:361 | 0.0 | 0.0 | E | -93.1 | 123.3 | NA | NA | NA | |||||||||||||
| 5cch | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | VAL | E:221 | E:361 | 0.0 | 0.0 | E | -103.2 | 126.1 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | F:221 | F:361 | 0.0 | 0.0 | E | -102.8 | 128.5 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 5cci | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | VAL | E:221 | E:361 | 0.0 | 0.0 | E | -97.2 | 122.6 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | F:221 | F:361 | 0.0 | 0.0 | E | -95.2 | 125.3 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6mti | 2 | P21707 | 86.79 | 6e-174 |
EM |
2019-04-24 | VAL | B:221 | 2:642 | 0.0 | 0.0 | E | -97.2 | 122.6 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | C:221 | 3:642 | 0.0 | 0.0 | E | -97.2 | 122.7 | 0.0 | 0.0 | 0.0 | |||||||||||||
| VAL | D:221 | 4:642 | 0.0 | 0.0 | E | -97.3 | 122.6 | 0.0 | 0.0 | 0.0 | |||||||||||||
| VAL | E:221 | 5:642 | 0.0 | 0.0 | E | -97.2 | 122.6 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 5kj7 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | VAL | E:221 | E:361 | 0.0 | 0.0 | E | -96.7 | 124.7 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | F:221 | F:361 | 0.0 | 0.0 | E | -108.8 | 122.0 | NA | NA | NA | |||||||||||||
| VAL | K:221 | K:361 | 0.0 | 0.0 | E | -96.4 | 125.5 | NA | NA | NA | |||||||||||||
| 5kj8 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | VAL | E:221 | E:361 | 0.0 | 0.0 | E | -97.4 | 118.1 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | F:221 | F:361 | 1.0 | 0.006 | E | -99.2 | 118.4 | NA | NA | NA | |||||||||||||
| VAL | K:221 | K:361 | 0.0 | 0.0 | E | -98.5 | 119.4 | NA | NA | NA | |||||||||||||
| 6tz3 | 1 | P21579 | 84.71 | 1e-84 |
X-RAY |
2020-05-13 | VAL | A:97 | A:362 | 0.0 | 0.0 | E | -103.7 | 131.1 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
9.414 6.434 |
C N |
O2 O |
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| 2yoa | 1 | P21707 | 87.42 | 2e-84 |
X-RAY |
2013-03-20 | VAL | A:92 | A:361 | 0.0 | 0.0 | E | -105.5 | 128.9 | 0.0 | 0.0 | 0.0 |
SCN HOH |
9.846 6.331 |
C N |
S O |
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| VAL | B:92 | B:361 | 0.0 | 0.0 | E | -103.8 | 130.5 | NA | NA | NA | |||||||||||||
| 5t0s | 1 | P46096 | 87.42 | 2e-84 |
X-RAY |
2017-06-14 | VAL | A:91 | A:361 | 0.0 | 0.0 | E | -96.6 | 127.7 | 0.0 | 0.0 | 0.0 |
HOH |
6.431 |
N |
O |
||
| 2lha | 1 | P21579 | 87.42 | 3e-84 |
NMR |
2012-05-02 | VAL | A:92 | A:361 | 0.0 | 0.0 | E | -92.1 | 140.3 | 0.0 | 0.0 | 0.0 | ||||||
| 5w5d | 6 | P21707 | 87.42 | 3e-84 |
X-RAY |
2017-08-23 | VAL | F:92 | F:361 | 0.0 | 0.0 | E | -105.9 | 124.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.161 |
N |
O |
||
| 6u4u | 1 | P21579 | 84.71 | 4e-84 |
X-RAY |
2020-05-13 | VAL | A:97 | A:362 | 0.0 | 0.0 | E | -101.0 | 131.4 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
8.641 5.179 |
C HG12 |
O1 O |
||
| 1tjm | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-28 | VAL | A:99 | A:361 | 0.0 | 0.0 | E | -103.1 | 127.6 | 0.0 | 0.0 | 0.0 |
SR HOH |
9.798 4.334 |
HG11 HG11 |
SR H2 |
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| 1tjx | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-11-23 | VAL | A:99 | A:361 | 0.0 | 0.0 | E | -102.1 | 128.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.523 |
HG11 |
H2 |
||
| 1uov | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-09 | VAL | A:99 | A:361 | 0.0 | 0.0 | E | -103.0 | 128.2 | 0.0 | 0.0 | 0.0 |
HOH |
6.469 |
N |
O |
||
| 1uow | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-16 | VAL | A:99 | A:361 | 0.0 | 0.0 | E | -102.0 | 128.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.114 |
CG1 |
O |
||
| 6u4w | 1 | P21579 | 84.08 | 7e-84 |
X-RAY |
2020-05-13 | VAL | A:97 | A:362 | 0.0 | 0.0 | E | -104.8 | 129.5 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
8.412 5.236 |
C HG12 |
O2 O |
||
| 2n1t | 5 | P21579 | 85.81 | 7e-84 |
NMR |
2015-06-03 | VAL | E:99 | E:361 | 2.0 | 0.013 | E | -109.6 | 132.8 | 2.0 | 0.013 | 0.0 | ||||||
| 4v11 | 1 | P21579 | 87.33 | 1e-83 |
X-RAY |
2015-02-25 | VAL | A:90 | A:362 | 0.0 | 0.0 | E | -98.2 | 129.4 | 0.0 | 0.0 | 0.0 |
HOH |
6.470 |
N |
O |
||
| 5vff | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | VAL | A:91 | A:361 | 0.0 | 0.0 | E | -96.1 | 128.1 | 0.0 | 0.0 | 0.0 |
HOH |
6.379 |
N |
O |
||
| 5vfg | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | VAL | A:91 | A:361 | 0.0 | 0.0 | E | -96.9 | 124.6 | 0.0 | 0.0 | 0.0 |
HOH |
6.349 |
N |
O |
||
| 6u41 | 1 | P21579 | 84.08 | 2e-83 |
X-RAY |
2020-05-13 | VAL | A:97 | A:362 | 0.0 | 0.0 | E | -103.7 | 131.2 | 0.0 | 0.0 | 0.0 |
SO4 HOH |
9.026 6.080 |
C HG12 |
O2 O |
||
| 5ccj | 1 | P21707 | 84.11 | 8e-80 |
X-RAY |
2015-08-12 | VAL | A:92 | A:361 | 0.0 | 0.0 | E | -104.7 | 130.1 | 0.0 | 0.0 | 0.0 |
GOL SO4 HOH |
9.846 8.244 6.404 |
C C N |
C1 O1 O |
||
| VAL | B:92 | B:361 | 0.0 | 0.0 | E | -105.6 | 134.0 | NA | NA | NA | |||||||||||||
| VAL | C:92 | C:361 | 0.0 | 0.0 | E | -104.0 | 131.7 | NA | NA | NA | |||||||||||||
| VAL | D:92 | D:361 | 0.0 | 0.0 | E | -104.7 | 132.9 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q8n9i0-f1 | 1 | Q8N9I0 | 100.0 | 0.0 | VAL | A:359 | A:359 | 0.0 | 0.0 | E | -90.5 | 127.3 | |