Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 202568413 . T A CCDS1427.1:NM_001136504.1:c.986aAg>aTg_NP_001129976.1:p.329K>M Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5w5c 6 P21707 86.52 1e-174 X-RAY
 2017-08-23 LYS F:192 F:331 71.0 0.355 -115.5 109.0 71.0 0.355 0.0 GOL
HOH
 7.274
2.698
 O
NZ
 O2
O
2r83 1 P21579 86.17 5e-174 X-RAY
 2008-02-12 LYS A:194 A:331 64.0 0.32 -105.3 137.4 64.0 0.32 0.0 HOH
 3.551
 CD
 O
LYS B:194 B:331 62.0 0.31 -105.5 136.7 62.0 0.31 0.0 HOH
 8.275
 O
 O
5ccg 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 LYS E:191 E:331 75.0 0.375 -94.8 106.4 63.0 0.315 0.06 D:P60881:0.06
 CA
 9.089
 O
 CA
LYS F:191 F:331 26.0 NA -93.3 107.3 26.0 NA NA CA
 9.434
 O
 CA
LYS K:191 K:331 84.0 0.42 -94.9 103.1 NA NA NA
5cch 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 LYS E:191 E:331 24.0 NA -108.8 134.9 24.0 NA NA CA
 8.205
 O
 CA
LYS F:191 F:331 76.0 0.38 -101.1 131.0 76.0 0.38 0.0 CA
CA
 6.780
8.920
 O
O
 CA
CA
5cci 5 P21707 86.79 6e-174 X-RAY
 2015-08-12 LYS E:191 E:331 68.0 0.34 -89.4 120.9 49.0 0.245 0.095 D:P60881:0.095
 MG
 8.085
 O
 MG
LYS F:191 F:331 96.0 0.48 -91.3 119.9 96.0 0.48 0.0 MG
 9.615
 O
 MG
6mti 2 P21707 86.79 6e-174 EM
 2019-04-24 LYS B:191 2:612 67.0 0.335 -89.4 121.0 51.0 0.255 0.08 N:P60881:0.08
 MG
 8.086
 O
 MG
LYS C:191 3:612 69.0 0.345 -89.4 120.9 57.0 0.285 0.06 J:P60881:0.06
 MG
 8.085
 O
 MG
LYS D:191 4:612 69.0 0.345 -89.3 120.9 61.0 0.305 0.04 V:P60881:0.04
 MG
 8.086
 O
 MG
LYS E:191 5:612 67.0 0.335 -89.4 121.0 53.0 0.265 0.07 Z:P60881:0.07
 MG
 8.085
 O
 MG
5kj7 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 LYS E:191 E:331 79.0 0.395 -95.4 102.2 62.0 0.31 0.085 D:P60881:0.085
 CA
 9.149
 O
 CA
LYS F:191 F:331 26.0 NA -93.9 112.0 NA NA NA
LYS K:191 K:331 88.0 0.44 -95.9 100.2 NA NA NA
5kj8 5 P21707 87.36 6e-174 X-RAY
 2016-10-19 LYS E:191 E:331 92.0 0.46 -94.4 109.8 65.0 0.325 0.135 D:P60881:0.135
 CA
 8.210
 O
 CA
LYS F:191 F:331 26.0 NA -93.7 110.7 NA NA NA
LYS K:191 K:331 90.0 0.45 -94.5 106.0 NA NA NA
6tz3 1 P21579 84.71 1e-84 X-RAY
 2020-05-13 LYS A:67 A:332 66.0 0.33 -103.1 144.1 66.0 0.33 0.0 HOH
 1.972
 HZ1
 O
2yoa 1 P21707 87.42 2e-84 X-RAY
 2013-03-20 LYS A:62 A:331 66.0 0.33 -108.0 125.5 66.0 0.33 0.0 CA
SEP
CA
SCN
SCN
HOH
 7.650
7.981
6.119
8.664
4.163
2.883
 O
O
O
N
CD
NZ
 CA
N
CA
S
S
O
LYS B:62 B:331 70.0 0.35 -105.6 117.9 NA NA NA
5t0s 1 P46096 87.42 2e-84 X-RAY
 2017-06-14 LYS A:61 A:331 67.0 0.335 -98.9 145.3 67.0 0.335 0.0 CD
HOH
 7.315
2.700
 O
NZ
 CD
O
2lha 1 P21579 87.42 3e-84 NMR
 2012-05-02 LYS A:62 A:331 140.0 0.7 -79.4 124.0 140.0 0.7 0.0 IHP
 3.555
 HA
 O41
5w5d 6 P21707 87.42 3e-84 X-RAY
 2017-08-23 LYS F:62 F:331 73.0 0.365 -121.0 112.9 73.0 0.365 0.0 HOH
 3.259
 C
 O
6u4u 1 P21579 84.71 4e-84 X-RAY
 2020-05-13 LYS A:67 A:332 65.0 0.325 -100.3 141.3 65.0 0.325 0.0 SO4
HOH
 7.345
1.946
 HB3
HZ3
 O4
O
1tjm 1 P21707 84.81 4e-84 X-RAY
 2004-09-28 LYS A:69 A:331 67.0 0.335 -105.1 136.9 67.0 0.335 0.0 SR
HOH
 7.457
1.074
 O
HZ1
 SR
H2
1tjx 1 P21707 84.81 4e-84 X-RAY
 2004-11-23 LYS A:69 A:331 67.0 0.335 -103.5 132.9 67.0 0.335 0.0 CA
HOH
 7.654
0.997
 O
HZ1
 CA
H2
1uov 1 P21707 84.81 4e-84 X-RAY
 2004-09-09 LYS A:69 A:331 69.0 0.345 -101.9 127.4 69.0 0.345 0.0 CA
CA
GOL
HOH
 7.589
6.818
5.403
2.769
 O
O
NZ
NZ
 CA
CA
C1
O
1uow 1 P21707 84.81 4e-84 X-RAY
 2004-09-16 LYS A:69 A:331 67.0 0.335 -103.3 132.4 67.0 0.335 0.0 CA
HOH
 7.674
2.273
 O
NZ
 CA
O
6u4w 1 P21579 84.08 7e-84 X-RAY
 2020-05-13 LYS A:67 A:332 68.0 0.34 -100.2 136.8 68.0 0.34 0.0 SO4
HOH
 8.020
1.971
 HB3
HZ1
 O4
O
2n1t 5 P21579 85.81 7e-84 NMR
 2015-06-03 LYS E:69 E:331 67.0 0.335 -112.6 107.9 67.0 0.335 0.0
4v11 1 P21579 87.33 1e-83 X-RAY
 2015-02-25 LYS A:60 A:332 66.0 0.33 -102.1 121.8 66.0 0.33 0.0 CA
HOH
 7.711
2.416
 O
NZ
 CA
O
5vff 1 P46096 86.75 2e-83 X-RAY
 2018-04-11 LYS A:61 A:331 76.0 0.38 -112.0 107.7 76.0 0.38 0.0 PB
HOH
 8.214
2.847
 O
NZ
 PB
O
5vfg 1 P46096 86.75 2e-83 X-RAY
 2018-04-11 LYS A:61 A:331 77.0 0.385 -110.4 118.1 77.0 0.385 0.0 PB
HOH
 8.086
2.505
 O
NZ
 PB
O
6u41 1 P21579 84.08 2e-83 X-RAY
 2020-05-13 LYS A:67 A:332 67.0 0.335 -101.4 145.4 67.0 0.335 0.0 SO4
HOH
 7.536
1.936
 HB3
HZ1
 O3
O
5ccj 1 P21707 84.11 8e-80 X-RAY
 2015-08-12 LYS A:62 A:331 67.0 0.335 -96.7 146.7 67.0 0.335 0.0 GOL
GOL
SO4
HOH
 7.459
8.462
7.899
2.852
 N
CB
NZ
NZ
 C3
O2
O2
O
LYS B:62 B:331 69.0 0.345 -100.2 140.1 NA NA NA
LYS C:62 C:331 67.0 0.335 -103.2 137.3 NA NA NA
LYS D:62 D:331 68.0 0.34 -93.1 146.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8n9i0-f1 1 Q8N9I0 100.0 0.0 LYS A:329 A:329 59.0 0.295 -103.3 117.4