Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 202569487 | . | G | A | CCDS1427.1:NM_001136504.1:c.917tCa>tTa_NP_001129976.1:p.306S>L | Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5w5c | 6 | P21707 | 86.52 | 1e-174 |
X-RAY |
2017-08-23 | SER | F:169 | F:308 | 5.0 | 0.043 | -99.5 | 133.7 | 5.0 | 0.043 | 0.0 |
GOL HOH |
2.900 3.340 |
N OG |
O2 O |
|||
| 2r83 | 1 | P21579 | 86.17 | 5e-174 |
X-RAY |
2008-02-12 | SER | A:171 | A:308 | 1.0 | 0.009 | -158.1 | 168.8 | 1.0 | 0.009 | 0.0 |
HOH |
5.219 |
C |
O |
|||
| SER | B:171 | B:308 | 1.0 | 0.009 | -158.1 | 168.3 | 1.0 | 0.009 | 0.0 |
HOH |
5.773 |
C |
O |
||||||||||
| 5ccg | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | SER | E:168 | E:308 | 0.0 | 0.0 | -168.4 | 161.9 | 0.0 | 0.0 | 0.0 |
CA CA |
5.386 7.240 |
C CA |
CA CA |
|||
| SER | F:168 | F:308 | 3.0 | 0.026 | -165.5 | 161.2 | 3.0 | 0.026 | 0.0 |
CA |
5.775 |
C |
CA |
||||||||||
| SER | K:168 | K:308 | 2.0 | 0.017 | -168.4 | 160.3 | NA | NA | NA | ||||||||||||||
| 5cch | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | SER | E:168 | E:308 | 16.0 | 0.139 | -139.9 | 154.6 | 16.0 | 0.139 | 0.0 |
CA CA |
2.953 6.152 |
OG OG |
CA CA |
|||
| SER | F:168 | F:308 | 65.0 | 0.565 | 360.0 | 169.6 | 65.0 | 0.565 | 0.0 |
CA CA |
4.087 4.196 |
C CA |
CA CA |
||||||||||
| 5cci | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | SER | E:168 | E:308 | 6.0 | 0.052 | B | -107.7 | 167.9 | 6.0 | 0.052 | 0.0 |
MG |
5.026 |
C |
MG |
||
| SER | F:168 | F:308 | 30.0 | 0.261 | 360.0 | 166.7 | 30.0 | 0.261 | 0.0 |
MG |
4.823 |
OG |
MG |
||||||||||
| 6mti | 2 | P21707 | 86.79 | 6e-174 |
EM |
2019-04-24 | SER | B:168 | 2:589 | 6.0 | 0.052 | B | -107.7 | 167.8 | 6.0 | 0.052 | 0.0 |
MG |
5.026 |
C |
MG |
||
| SER | C:168 | 3:589 | 6.0 | 0.052 | B | -107.7 | 167.9 | 6.0 | 0.052 | 0.0 |
MG |
5.025 |
C |
MG |
|||||||||
| SER | D:168 | 4:589 | 6.0 | 0.052 | B | -107.7 | 167.8 | 6.0 | 0.052 | 0.0 |
MG |
5.026 |
C |
MG |
|||||||||
| SER | E:168 | 5:589 | 6.0 | 0.052 | B | -107.7 | 167.8 | 6.0 | 0.052 | 0.0 |
MG |
5.025 |
C |
MG |
|||||||||
| 5kj7 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | SER | E:168 | E:308 | 0.0 | 0.0 | -166.7 | 164.5 | 0.0 | 0.0 | 0.0 |
CA CA |
5.312 7.266 |
C CA |
CA CA |
|||
| SER | F:168 | F:308 | 2.0 | 0.017 | -161.3 | 164.7 | NA | NA | NA | ||||||||||||||
| SER | K:168 | K:308 | 1.0 | 0.009 | -166.8 | 162.8 | NA | NA | NA | ||||||||||||||
| 5kj8 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | SER | E:168 | E:308 | 1.0 | 0.009 | -172.7 | 162.8 | 1.0 | 0.009 | 0.0 |
CA CA |
4.263 6.382 |
C CA |
CA CA |
|||
| SER | F:168 | F:308 | 3.0 | 0.026 | -168.1 | 160.5 | NA | NA | NA | ||||||||||||||
| SER | K:168 | K:308 | 0.0 | 0.0 | -171.2 | 160.9 | NA | NA | NA | ||||||||||||||
| 6tz3 | 1 | P21579 | 84.71 | 1e-84 |
X-RAY |
2020-05-13 | SER | A:44 | A:309 | 0.0 | 0.0 | -139.0 | 166.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.381 |
HA |
O |
|||
| 2yoa | 1 | P21707 | 87.42 | 2e-84 |
X-RAY |
2013-03-20 | SER | A:39 | A:308 | 0.0 | 0.0 | -143.4 | 164.5 | 0.0 | 0.0 | 0.0 |
CA CA SEP CA SCN HOH |
4.841 6.474 6.113 7.010 8.313 3.479 |
C OG C C O N |
CA CA N CA N O |
|||
| SER | B:39 | B:308 | 0.0 | 0.0 | -143.6 | 164.2 | NA | NA | NA | ||||||||||||||
| 5t0s | 1 | P46096 | 87.42 | 2e-84 |
X-RAY |
2017-06-14 | SER | A:38 | A:308 | 0.0 | 0.0 | -151.1 | 158.6 | 0.0 | 0.0 | 0.0 |
CD HOH |
4.667 4.174 |
C N |
CD O |
|||
| 2lha | 1 | P21579 | 87.42 | 3e-84 |
NMR |
2012-05-02 | SER | A:39 | A:308 | 3.0 | 0.026 | B | -93.0 | 165.0 | 3.0 | 0.026 | 0.0 |
IHP |
7.659 |
O |
O21 |
||
| 5w5d | 6 | P21707 | 87.42 | 3e-84 |
X-RAY |
2017-08-23 | SER | F:39 | F:308 | 2.0 | 0.017 | -87.3 | 166.0 | 2.0 | 0.017 | 0.0 |
HOH |
2.189 |
OG |
O |
|||
| 6u4u | 1 | P21579 | 84.71 | 4e-84 |
X-RAY |
2020-05-13 | SER | A:44 | A:309 | 11.0 | 0.096 | -100.4 | 121.4 | 11.0 | 0.096 | 0.0 |
SO4 HOH |
6.346 2.132 |
HB3 H |
O2 O |
|||
| 1tjm | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-28 | SER | A:46 | A:308 | 0.0 | 0.0 | -143.6 | 164.1 | 0.0 | 0.0 | 0.0 |
SR HOH |
4.194 1.510 |
HA HB3 |
SR H1 |
|||
| 1tjx | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-11-23 | SER | A:46 | A:308 | 0.0 | 0.0 | -143.9 | 166.1 | 0.0 | 0.0 | 0.0 |
CA CA HOH |
5.722 4.251 2.063 |
HA HA HB3 |
CA CA O |
|||
| 1uov | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-09 | SER | A:46 | A:308 | 0.0 | 0.0 | -145.8 | 168.7 | 0.0 | 0.0 | 0.0 |
CA CA CA HOH |
6.619 4.891 4.692 3.307 |
CA C O N |
CA CA CA O |
|||
| 1uow | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-16 | SER | A:46 | A:308 | 0.0 | 0.0 | -144.2 | 166.4 | 0.0 | 0.0 | 0.0 |
CA CA HOH |
6.674 4.898 2.909 |
CA C CB |
CA CA O |
|||
| 6u4w | 1 | P21579 | 84.08 | 7e-84 |
X-RAY |
2020-05-13 | SER | A:44 | A:309 | 3.0 | 0.026 | -109.3 | 121.0 | 3.0 | 0.026 | 0.0 |
SO4 HOH |
6.165 2.253 |
HB3 H |
O4 O |
|||
| 2n1t | 5 | P21579 | 85.81 | 7e-84 |
NMR |
2015-06-03 | SER | E:46 | E:308 | 3.0 | 0.026 | -64.7 | 147.9 | 3.0 | 0.026 | 0.0 | |||||||
| 4v11 | 1 | P21579 | 87.33 | 1e-83 |
X-RAY |
2015-02-25 | SER | A:37 | A:309 | 0.0 | 0.0 | -144.3 | 164.8 | 0.0 | 0.0 | 0.0 |
CA CA HOH |
4.736 6.415 3.814 |
C CA O |
CA CA O |
|||
| 5vff | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | SER | A:38 | A:308 | 1.0 | 0.009 | -60.7 | 158.6 | 1.0 | 0.009 | 0.0 |
PB HOH |
4.990 2.962 |
C N |
PB O |
|||
| 5vfg | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | SER | A:38 | A:308 | 0.0 | 0.0 | -144.2 | 165.8 | 0.0 | 0.0 | 0.0 |
PB HOH |
5.124 6.789 |
C N |
PB O |
|||
| 6u41 | 1 | P21579 | 84.08 | 2e-83 |
X-RAY |
2020-05-13 | SER | A:44 | A:309 | 11.0 | 0.096 | -91.5 | 119.6 | 11.0 | 0.096 | 0.0 |
SO4 HOH |
6.004 2.211 |
HB3 H |
O4 O |
|||
| 5ccj | 1 | P21707 | 84.11 | 8e-80 |
X-RAY |
2015-08-12 | SER | A:39 | A:308 | 1.0 | 0.009 | -149.9 | 165.2 | 1.0 | 0.009 | 0.0 |
GOL SO4 HOH |
7.032 9.734 7.286 |
N OG O |
O1 O3 O |
|||
| SER | B:39 | B:308 | 3.0 | 0.026 | -94.3 | 119.0 | NA | NA | NA | ||||||||||||||
| SER | C:39 | C:308 | 2.0 | 0.017 | -94.1 | 123.2 | NA | NA | NA | ||||||||||||||
| SER | D:39 | D:308 | 3.0 | 0.026 | -94.2 | 114.7 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q8n9i0-f1 | 1 | Q8N9I0 | 100.0 | 0.0 | SER | A:306 | A:306 | 0.0 | 0.0 | -147.9 | 162.3 | ||