Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 202569539 | . | C | A | CCDS1427.1:NM_001136504.1:c.865Gtc>Ttc_NP_001129976.1:p.289V>F | Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5w5c | 6 | P21707 | 86.52 | 1e-174 |
X-RAY |
2017-08-23 | VAL | F:152 | F:291 | 0.0 | 0.0 | E | -112.4 | 124.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.290 |
N |
O |
||
| 2r83 | 1 | P21579 | 86.17 | 5e-174 |
X-RAY |
2008-02-12 | VAL | A:154 | A:291 | 0.0 | 0.0 | E | -115.0 | 120.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.206 |
C |
O |
||
| VAL | B:154 | B:291 | 0.0 | 0.0 | E | -115.4 | 119.8 | 0.0 | 0.0 | 0.0 |
HOH |
6.201 |
O |
O |
|||||||||
| 5ccg | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | VAL | E:151 | E:291 | 0.0 | 0.0 | E | -108.2 | 106.8 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | F:151 | F:291 | 1.0 | 0.006 | E | -108.9 | 104.3 | 1.0 | 0.006 | 0.0 | |||||||||||||
| VAL | K:151 | K:291 | 0.0 | 0.0 | E | -109.1 | 105.2 | NA | NA | NA | |||||||||||||
| 5cch | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | VAL | E:151 | E:291 | 0.0 | 0.0 | E | -118.1 | 119.4 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | F:151 | F:291 | 0.0 | 0.0 | E | -118.6 | 120.1 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 5cci | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | VAL | E:151 | E:291 | 0.0 | 0.0 | E | -98.2 | 109.5 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | F:151 | F:291 | 0.0 | 0.0 | E | -99.2 | 108.9 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 6mti | 2 | P21707 | 86.79 | 6e-174 |
EM |
2019-04-24 | VAL | B:151 | 2:572 | 0.0 | 0.0 | E | -98.3 | 109.6 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | C:151 | 3:572 | 0.0 | 0.0 | E | -98.2 | 109.5 | 0.0 | 0.0 | 0.0 | |||||||||||||
| VAL | D:151 | 4:572 | 0.0 | 0.0 | E | -98.2 | 109.5 | 0.0 | 0.0 | 0.0 | |||||||||||||
| VAL | E:151 | 5:572 | 0.0 | 0.0 | E | -98.1 | 109.4 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 5kj7 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | VAL | E:151 | E:291 | 0.0 | 0.0 | E | -109.0 | 107.9 | 0.0 | 0.0 | 0.0 | ||||||
| VAL | F:151 | F:291 | 0.0 | 0.0 | E | -118.0 | 111.0 | NA | NA | NA | |||||||||||||
| VAL | K:151 | K:291 | 0.0 | 0.0 | E | -108.7 | 108.2 | NA | NA | NA | |||||||||||||
| 5kj8 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | VAL | E:151 | E:291 | 1.0 | 0.006 | E | -108.3 | 107.2 | 1.0 | 0.006 | 0.0 | ||||||
| VAL | F:151 | F:291 | 0.0 | 0.0 | E | -108.1 | 106.3 | NA | NA | NA | |||||||||||||
| VAL | K:151 | K:291 | 0.0 | 0.0 | E | -108.7 | 106.3 | NA | NA | NA | |||||||||||||
| 6tz3 | 1 | P21579 | 84.71 | 1e-84 |
X-RAY |
2020-05-13 | VAL | A:27 | A:292 | 0.0 | 0.0 | E | -120.1 | 123.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.678 |
HA |
O |
||
| 2yoa | 1 | P21707 | 87.42 | 2e-84 |
X-RAY |
2013-03-20 | VAL | A:22 | A:291 | 0.0 | 0.0 | E | -119.5 | 122.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.306 |
N |
O |
||
| VAL | B:22 | B:291 | 0.0 | 0.0 | E | -117.3 | 122.8 | NA | NA | NA | |||||||||||||
| 5t0s | 1 | P46096 | 87.42 | 2e-84 |
X-RAY |
2017-06-14 | VAL | A:21 | A:291 | 0.0 | 0.0 | E | -114.0 | 122.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.321 |
N |
O |
||
| 2lha | 1 | P21579 | 87.42 | 3e-84 |
NMR |
2012-05-02 | VAL | A:22 | A:291 | 12.0 | 0.077 | E | -82.7 | 112.0 | 12.0 | 0.077 | 0.0 | ||||||
| 5w5d | 6 | P21707 | 87.42 | 3e-84 |
X-RAY |
2017-08-23 | VAL | F:22 | F:291 | 0.0 | 0.0 | E | -112.5 | 114.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.324 |
CA |
O |
||
| 6u4u | 1 | P21579 | 84.71 | 4e-84 |
X-RAY |
2020-05-13 | VAL | A:27 | A:292 | 0.0 | 0.0 | E | -123.0 | 121.1 | 0.0 | 0.0 | 0.0 |
HOH |
3.640 |
HA |
O |
||
| 1tjm | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-28 | VAL | A:29 | A:291 | 0.0 | 0.0 | E | -120.2 | 123.3 | 0.0 | 0.0 | 0.0 |
HOH |
2.967 |
HA |
H1 |
||
| 1tjx | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-11-23 | VAL | A:29 | A:291 | 0.0 | 0.0 | E | -119.5 | 123.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.669 |
HA |
O |
||
| 1uov | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-09 | VAL | A:29 | A:291 | 0.0 | 0.0 | E | -120.4 | 122.6 | 0.0 | 0.0 | 0.0 |
GOL HOH |
9.437 4.075 |
O N |
O3 O |
||
| 1uow | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-16 | VAL | A:29 | A:291 | 0.0 | 0.0 | E | -119.6 | 124.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.131 |
N |
O |
||
| 6u4w | 1 | P21579 | 84.08 | 7e-84 |
X-RAY |
2020-05-13 | VAL | A:27 | A:292 | 0.0 | 0.0 | E | -121.1 | 123.3 | 0.0 | 0.0 | 0.0 |
HOH |
3.737 |
HA |
O |
||
| 2n1t | 5 | P21579 | 85.81 | 7e-84 |
NMR |
2015-06-03 | VAL | E:29 | E:291 | 6.0 | 0.039 | E | -117.5 | 128.8 | 6.0 | 0.039 | 0.0 | ||||||
| 4v11 | 1 | P21579 | 87.33 | 1e-83 |
X-RAY |
2015-02-25 | VAL | A:20 | A:292 | 0.0 | 0.0 | E | -111.3 | 120.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.390 |
N |
O |
||
| 5vff | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | VAL | A:21 | A:291 | 0.0 | 0.0 | E | -115.4 | 123.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.350 |
N |
O |
||
| 5vfg | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | VAL | A:21 | A:291 | 0.0 | 0.0 | E | -112.4 | 120.0 | 0.0 | 0.0 | 0.0 |
HOH |
4.375 |
CA |
O |
||
| 6u41 | 1 | P21579 | 84.08 | 2e-83 |
X-RAY |
2020-05-13 | VAL | A:27 | A:292 | 0.0 | 0.0 | E | -121.7 | 122.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.663 |
HA |
O |
||
| 5ccj | 1 | P21707 | 84.11 | 8e-80 |
X-RAY |
2015-08-12 | VAL | A:22 | A:291 | 0.0 | 0.0 | E | -113.4 | 123.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.380 |
CA |
O |
||
| VAL | B:22 | B:291 | 0.0 | 0.0 | E | -115.1 | 125.1 | NA | NA | NA | |||||||||||||
| VAL | C:22 | C:291 | 0.0 | 0.0 | E | -113.9 | 121.4 | NA | NA | NA | |||||||||||||
| VAL | D:22 | D:291 | 0.0 | 0.0 | E | -112.5 | 128.8 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q8n9i0-f1 | 1 | Q8N9I0 | 100.0 | 0.0 | VAL | A:289 | A:289 | 0.0 | 0.0 | E | -114.0 | 112.0 | |