Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 202569599 | . | C | A | CCDS1427.1:NM_001136504.1:c.805Gag>Tag_NP_001129976.1:p.269E>* | Homo sapiens synaptotagmin 2 (SYT2), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5w5c | 6 | P21707 | 86.52 | 1e-174 |
X-RAY |
2017-08-23 | GLU | F:132 | F:271 | 174.0 | 0.916 | -91.6 | -39.8 | 150.0 | 0.789 | 0.127 |
E:P63041:0.126 |
HOH |
3.085 |
O |
O |
||
| 2r83 | 1 | P21579 | 86.17 | 5e-174 |
X-RAY |
2008-02-12 | GLU | A:134 | A:271 | 13.0 | 0.068 | -86.1 | 113.6 | 13.0 | 0.068 | 0.0 | |||||||
| GLU | B:134 | B:271 | 19.0 | 0.1 | -86.9 | 114.2 | 19.0 | 0.1 | 0.0 |
HOH |
8.998 |
N |
O |
||||||||||
| 5ccg | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | GLU | E:131 | E:271 | 140.0 | 0.737 | -67.8 | 144.4 | 140.0 | 0.737 | 0.0 | |||||||
| GLU | F:131 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| GLU | K:131 | K:271 | 81.0 | NA | -55.7 | 140.6 | NA | NA | NA | ||||||||||||||
| 5cch | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | GLU | E:131 | E:271 | 143.0 | 0.753 | -62.5 | -38.6 | 143.0 | 0.753 | 0.0 | |||||||
| GLU | F:131 | F:271 | 95.0 | NA | 360.0 | -35.8 | 95.0 | NA | NA | ||||||||||||||
| 5cci | 5 | P21707 | 86.79 | 6e-174 |
X-RAY |
2015-08-12 | GLU | E:131 | E:271 | 95.0 | NA | S | -79.1 | -39.2 | 95.0 | NA | NA | ||||||
| GLU | F:131 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6mti | 2 | P21707 | 86.79 | 6e-174 |
EM |
2019-04-24 | GLU | B:131 | 2:552 | 93.0 | NA | S | -79.2 | -39.1 | 93.0 | NA | NA | ||||||
| GLU | C:131 | 3:552 | 95.0 | NA | S | -79.0 | -39.3 | 95.0 | NA | NA | |||||||||||||
| GLU | D:131 | 4:552 | 96.0 | NA | S | -79.1 | -39.3 | 96.0 | NA | NA | |||||||||||||
| GLU | E:131 | 5:552 | 96.0 | NA | S | -79.1 | -39.2 | 96.0 | NA | NA | |||||||||||||
| 5kj7 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | GLU | E:131 | E:271 | 145.0 | 0.763 | -61.5 | 143.9 | 145.0 | 0.763 | 0.0 | |||||||
| GLU | F:131 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| GLU | K:131 | K:271 | 84.0 | NA | -61.3 | 142.1 | NA | NA | NA | ||||||||||||||
| 5kj8 | 5 | P21707 | 87.36 | 6e-174 |
X-RAY |
2016-10-19 | GLU | E:131 | E:271 | 61.0 | NA | -132.5 | 145.3 | 61.0 | NA | NA | |||||||
| GLU | F:131 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| GLU | K:131 | K:271 | 62.0 | NA | -63.0 | 140.4 | NA | NA | NA | ||||||||||||||
| 6tz3 | 1 | P21579 | 84.71 | 1e-84 |
X-RAY |
2020-05-13 | GLU | A:7 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2yoa | 1 | P21707 | 87.42 | 2e-84 |
X-RAY |
2013-03-20 | GLU | A:2 | A:271 | 104.0 | 0.547 | -52.3 | 137.6 | 104.0 | 0.547 | 0.0 |
HOH |
2.687 |
O |
O |
|||
| GLU | B:2 | B:271 | 159.0 | 0.837 | 360.0 | 135.4 | NA | NA | NA | ||||||||||||||
| 5t0s | 1 | P46096 | 87.42 | 2e-84 |
X-RAY |
2017-06-14 | GLU | A:1 | A:271 | 175.0 | 0.921 | 360.0 | 147.8 | 175.0 | 0.921 | 0.0 |
HOH |
2.220 |
OE1 |
O |
|||
| 2lha | 1 | P21579 | 87.42 | 3e-84 |
NMR |
2012-05-02 | GLU | A:2 | A:271 | 188.0 | 0.989 | 360.0 | 136.0 | 188.0 | 0.989 | 0.0 | |||||||
| 5w5d | 6 | P21707 | 87.42 | 3e-84 |
X-RAY |
2017-08-23 | GLU | F:2 | F:271 | 83.0 | NA | 66.8 | -1.0 | 83.0 | NA | NA |
HOH |
5.795 |
C |
O |
|||
| 6u4u | 1 | P21579 | 84.71 | 4e-84 |
X-RAY |
2020-05-13 | GLU | A:7 | A:272 | 150.0 | 0.789 | 360.0 | 118.8 | 150.0 | 0.789 | 0.0 |
SO4 HOH |
2.461 2.237 |
HA N |
O3 O |
|||
| 1tjm | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-28 | GLU | A:9 | A:271 | 52.0 | 0.274 | G | -77.0 | -14.3 | 52.0 | 0.274 | 0.0 |
GOL HOH |
8.972 2.633 |
OE1 O |
H12 O |
||
| 1tjx | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-11-23 | GLU | A:9 | A:271 | 53.0 | 0.279 | G | -81.9 | -12.6 | 53.0 | 0.279 | 0.0 |
GOL HOH |
8.924 1.738 |
OE1 HG2 |
H12 H1 |
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| 1uov | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-09 | GLU | A:9 | A:271 | 98.0 | 0.516 | -92.2 | -4.6 | 98.0 | 0.516 | 0.0 |
HOH |
2.809 |
CB |
O |
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| 1uow | 1 | P21707 | 84.81 | 4e-84 |
X-RAY |
2004-09-16 | GLU | A:9 | A:271 | 53.0 | 0.279 | G | -81.6 | -12.7 | 53.0 | 0.279 | 0.0 |
GOL HOH |
9.681 3.070 |
OE1 OE2 |
O1 O |
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| 6u4w | 1 | P21579 | 84.08 | 7e-84 |
X-RAY |
2020-05-13 | GLU | A:7 | A:272 | 236.0 | 1.0 | 360.0 | -0.5 | 236.0 | 1.0 | 0.0 |
HOH |
3.357 |
O |
O |
|||
| 2n1t | 5 | P21579 | 85.81 | 7e-84 |
NMR |
2015-06-03 | GLU | E:9 | E:271 | 107.0 | 0.563 | T | -95.8 | 0.5 | 107.0 | 0.563 | 0.0 | ||||||
| 5vff | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | GLU | A:1 | A:271 | 187.0 | 0.984 | 360.0 | 128.7 | 187.0 | 0.984 | 0.0 |
HOH |
2.348 |
OE2 |
O |
|||
| 5vfg | 1 | P46096 | 86.75 | 2e-83 |
X-RAY |
2018-04-11 | GLU | A:1 | A:271 | 179.0 | 0.942 | 360.0 | 116.0 | 179.0 | 0.942 | 0.0 |
HOH |
2.597 |
N |
O |
|||
| 6u41 | 1 | P21579 | 84.08 | 2e-83 |
X-RAY |
2020-05-13 | GLU | A:7 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 5ccj | 1 | P21707 | 84.11 | 8e-80 |
X-RAY |
2015-08-12 | GLU | A:2 | A:271 | 181.0 | 0.953 | 360.0 | 152.5 | 181.0 | 0.953 | 0.0 |
SO4 HOH |
4.512 2.437 |
OE2 N |
O1 O |
|||
| GLU | B:2 | B:271 | 172.0 | 0.905 | 360.0 | 145.7 | NA | NA | NA | ||||||||||||||
| GLU | C:2 | C:271 | 179.0 | 0.942 | 360.0 | 150.1 | NA | NA | NA | ||||||||||||||
| GLU | D:2 | D:271 | 116.0 | 0.611 | -67.9 | 143.8 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q8n9i0-f1 | 1 | Q8N9I0 | 100.0 | 0.0 | GLU | A:269 | A:269 | 137.0 | 0.721 | -48.9 | 112.9 | ||