Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 203834245 . T A CCDS30979.1:NM_003094.2:c.221cTg>cAg_NP_003085.1:p.74L>Q Homo sapiens small nuclear ribonucleoprotein polypeptide E (SNRPE), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4f7u 3 P62305 100.0 3e-64 X-RAY
 2013-01-30 LEU E:74 E:3074 50.0 0.294 E -105.2 -10.3 7.0 0.041 0.253 G:P62321:0.253
 HOH
 3.457
 N
 O
LEU F:74 H:3074 53.0 0.312 E -105.5 -7.7 NA NA NA
4pjo 5 P62304 100.0 3e-64 X-RAY
 2014-12-31 LEU E:74 E:74 62.0 0.365 E -120.1 -36.9 14.0 0.082 0.283 F:P62306:0.282
LEU P:74 e:74 62.0 0.365 E -118.9 -38.1 NA NA NA
LEU AA:74 S:74 52.0 0.306 -135.3 -179.9 NA NA NA
LEU LA:74 s:74 72.0 0.424 E -119.0 -36.5 NA NA NA
4v98 3 P62304 100.0 3e-64 X-RAY
 2014-07-09 LEU C:74 AK:3060 54.0 0.318 E -113.8 -14.0 9.0 0.053 0.265 D:P62306:0.265
LEU K:74 AC:3060 54.0 0.318 E -113.8 -14.1 NA NA NA
LEU S:74 AS:3060 52.0 0.306 E -113.6 -13.8 NA NA NA
LEU AA:74 Aa:3060 52.0 0.306 E -113.6 -13.7 NA NA NA
LEU IA:74 Ai:3060 54.0 0.318 E -113.5 -14.2 NA NA NA
LEU QA:74 Aq:3060 52.0 0.306 E -113.4 -14.0 NA NA NA
LEU CB:74 Ay:3060 53.0 0.312 E -113.7 -14.0 NA NA NA
LEU GB:74 BC:3060 53.0 0.312 E -113.4 -13.8 NA NA NA
LEU OB:74 BK:3060 52.0 0.306 E -113.6 -13.8 NA NA NA
LEU WB:74 BS:3060 52.0 0.306 E -113.6 -13.8 NA NA NA
LEU EC:74 Ba:3060 55.0 0.324 E -113.8 -13.7 NA NA NA
LEU MC:74 Bi:3060 54.0 0.318 E -113.8 -13.7 NA NA NA
LEU UC:74 Bq:3060 53.0 0.312 E -113.7 -13.6 NA NA NA
LEU GD:74 By:3060 55.0 0.324 E -113.7 -13.5 NA NA NA
LEU KD:74 CC:3060 51.0 0.3 E -113.7 -13.5 NA NA NA
LEU SD:74 CK:3060 51.0 0.3 E -113.8 -13.4 NA NA NA
LEU AE:74 CS:3060 51.0 0.3 E -113.6 -14.0 NA NA NA
LEU IE:74 Ca:3060 51.0 0.3 E -113.6 -14.0 NA NA NA
LEU QE:74 Ci:3060 51.0 0.3 E -113.3 -13.7 NA NA NA
LEU YE:74 Cq:3060 54.0 0.318 E -113.8 -13.4 NA NA NA
4wzj 6 P62304 100.0 3e-64 X-RAY
 2015-01-14 LEU F:74 E:74 45.0 0.265 E -117.7 -33.5 11.0 0.065 0.2 E:P62306:0.2
 G
 9.154
 CD2
 O3'
LEU M:74 L:74 44.0 0.259 E -119.6 -33.3 NA NA NA
LEU T:74 S:74 44.0 0.259 E -118.5 -32.7 NA NA NA
LEU AA:74 EE:74 45.0 0.265 E -119.1 -33.3 NA NA NA
LEU HA:74 LL:74 46.0 0.271 E -118.5 -33.2 NA NA NA
LEU OA:74 SS:74 44.0 0.259 E -119.0 -33.4 NA NA NA
LEU VA:74 EEE:74 44.0 0.259 E -118.3 -32.3 NA NA NA
LEU CB:74 LLL:74 44.0 0.259 E -118.6 -33.1 NA NA NA
LEU JB:74 SSS:74 45.0 0.265 E -118.8 -33.6 NA NA NA
LEU QB:74 EEEE:74 44.0 0.259 E -119.1 -33.5 NA NA NA
LEU XB:74 LLLL:74 44.0 0.259 E -118.7 -34.8 NA NA NA
LEU EC:74 SSSS:74 44.0 0.259 E -119.3 -33.4 NA NA NA
5mqf 24 P62304 100.0 3e-64 EM
 2017-03-22 LEU AA:74 c:74 64.0 NA E -127.6 -59.8 51.0 NA NA Z:P62306:NA
LEU HA:74 j:74 67.0 NA E -118.3 -32.3 49.0 NA NA GA:P62306:NA
5o9z 21 P62304 100.0 3e-64 EM
 2017-08-16 LEU U:74 c:74 43.0 NA E -116.6 134.0 27.0 NA NA T:P62306:NA
LEU BA:74 j:74 44.0 NA E -114.6 133.3 34.0 NA NA AA:P62306:NA
LEU VA:74 U:74 NA NA NA NA NA NA NA NA
5xjc 32 P62304 100.0 3e-64 EM
 2017-07-05 LEU FA:74 e:74 44.0 0.259 E -117.7 -33.5 11.0 0.065 0.194 EA:P62306:0.194
LEU MA:74 l:74 45.0 0.265 E -117.8 -33.5 11.0 0.065 0.2 LA:P62306:0.2
5xjl 4 P62304 100.0 3e-64 X-RAY
 2018-05-02 LEU D:74 E:74 57.0 0.335 E -105.4 -42.4 16.0 0.094 0.241 E:P62306:0.241
 HOH
 7.712
 N
 O
5xjq 4 P62304 100.0 3e-64 X-RAY
 2018-07-04 LEU D:74 E:74 61.0 0.359 E -108.5 -34.2 16.0 0.094 0.265 E:P62306:0.265
5xjr 4 P62304 100.0 3e-64 X-RAY
 2018-07-04 LEU D:74 E:74 62.0 0.365 E -108.2 -33.7 15.0 0.088 0.277 E:P62306:0.276
5xjs 4 P62304 100.0 3e-64 X-RAY
 2018-07-04 LEU D:74 E:74 72.0 0.424 E -115.3 -38.6 17.0 0.1 0.324 E:P62306:0.324
5xjt 4 P62304 100.0 3e-64 X-RAY
 2018-07-04 LEU D:74 E:74 58.0 0.341 E -107.9 -19.1 13.0 0.076 0.265 E:P62306:0.265
5xju 4 P62304 100.0 3e-64 X-RAY
 2018-07-04 LEU D:74 E:74 64.0 0.376 E -102.4 -29.7 15.0 0.088 0.288 E:P62306:0.288
5yzg 38 P62304 100.0 3e-64 EM
 2018-08-08 LEU OA:74 l:74 46.0 0.271 E -117.7 -33.6 10.0 0.059 0.212 NA:P62306:0.212
LEU XA:74 e:74 42.0 0.247 E -117.7 -33.5 10.0 0.059 0.188 WA:P62306:0.188
5z56 11 P62304 100.0 3e-64 EM
 2018-09-19 LEU K:74 e:74 66.0 NA E -117.7 -33.5 49.0 NA NA J:P62306:NA
LEU U:74 l:74 66.0 NA E -117.7 -33.6 48.0 NA NA T:P62306:NA
5z57 11 P62304 100.0 3e-64 EM
 2018-09-19 LEU K:74 e:74 66.0 NA E -117.7 -33.5 49.0 NA NA J:P62306:NA
LEU U:74 l:74 66.0 NA E -117.7 -33.6 48.0 NA NA T:P62306:NA
5z58 11 P62304 100.0 3e-64 EM
 2018-09-19 LEU K:74 e:74 66.0 NA E -117.7 -33.5 49.0 NA NA J:P62306:NA
LEU U:74 l:74 66.0 NA E -117.7 -33.6 48.0 NA NA T:P62306:NA
6ah0 6 P62304 100.0 3e-64 EM
 2018-11-14 LEU F:74 c:74 36.0 NA E -116.5 134.1 36.0 NA NA
LEU BA:74 l:74 63.0 NA E -117.6 -33.6 54.0 NA NA AA:P62306:NA
LEU XA:74 R:74 39.0 NA E -114.5 133.4 39.0 NA NA
6ahd 17 ? 100.0 3e-64 EM
 2018-11-14 LEU Q:74 e:74 62.0 NA E -117.6 -33.5 52.0 NA NA P:None:NA
LEU HA:74 m:74 61.0 NA E -117.6 -33.6 52.0 NA NA GA:None:NA
LEU XA:74 R:74 40.0 NA E -114.5 133.3 40.0 NA NA
6ff7 41 P62304 100.0 3e-64 EM
 2019-03-13 LEU RA:74 c:74 51.0 NA E -139.2 151.0 38.0 NA NA QA:P62306:NA
LEU YA:74 j:74 67.0 NA E -118.4 -32.2 49.0 NA NA XA:P62306:NA
6icz 34 P62304 100.0 3e-64 EM
 2019-03-13 LEU HA:74 l:74 67.0 NA E -117.7 -33.6 50.0 NA NA GA:P62306:NA
LEU RA:74 e:74 66.0 NA E -117.8 -33.4 49.0 NA NA QA:P62306:NA
6id0 25 P62304 100.0 3e-64 EM
 2019-03-13 LEU Y:74 e:74 66.0 NA E -117.7 -33.4 48.0 NA NA X:P62306:NA
LEU KA:74 l:74 66.0 NA E -117.7 -33.5 48.0 NA NA JA:P62306:NA
6id1 24 P62304 100.0 3e-64 EM
 2019-03-13 LEU X:74 e:74 66.0 NA E -117.8 -33.4 50.0 NA NA W:P62306:NA
LEU MA:74 l:74 67.0 NA E -117.7 -33.5 50.0 NA NA LA:P62306:NA
6qw6 11 P62304 100.0 3e-64 EM
 2019-04-17 LEU K:74 4e:74 75.0 0.441 E -121.6 -54.2 15.0 0.088 0.353 L:P62306:0.353
 G
 8.701
 CD2
 O3'
LEU Z:74 5e:74 61.0 0.359 E -111.1 -23.0 4.0 0.024 0.335 AA:P62306:0.335
6qx9 7 P62304 100.0 3e-64 EM
 2019-04-17 LEU G:74 5e:74 61.0 0.359 E -111.0 -23.1 4.0 0.024 0.335 HA:P62306:0.335
LEU N:74 4e:74 75.0 0.441 E -121.5 -54.2 15.0 0.088 0.353 OA:P62306:0.353
 G
 8.702
 CD2
 O3'
LEU VA:74 1e:74 70.0 0.412 E -118.9 -36.5 19.0 0.112 0.3 M:P62306:0.3
LEU EB:74 2e:74 68.0 0.4 E -127.2 -34.1 13.0 0.076 0.324 Y:P62306:0.324
6v4x 4 P62304 100.0 3e-64 EM
 2020-02-19 LEU D:74 E:74 57.0 0.335 E -112.6 -57.2 17.0 0.1 0.235 C:P62306:0.235
6y53 14 P62304 100.0 3e-64 EM
 2020-06-17 LEU N:74 j:74 78.0 NA E -125.4 -35.8 70.0 NA NA O:P62306:NA
6y5q 19 P62304 100.0 3e-64 EM
 2020-06-17 LEU S:74 j:74 78.0 NA E -125.4 -35.8 70.0 NA NA T:P62306:NA
7a5p 25 P62304 100.0 3e-64 EM
 2020-10-14 LEU BA:74 e:74 66.0 NA E -120.7 -34.5 48.0 NA NA CA:P62306:NA
LEU GA:74 j:74 66.0 NA E -120.2 -34.5 47.0 NA NA FA:P62306:NA
7abg 48 P62304 100.0 3e-64 EM
 2020-12-23 LEU VA:74 j:74 72.0 NA E -127.2 -34.1 50.0 NA NA RA:P62306:NA
LEU BB:74 c:74 41.0 NA E -116.5 134.3 26.0 NA NA CB:P62306:NA
7abi 40 P62304 100.0 3e-64 EM
 2021-02-10 LEU PA:74 j:74 72.0 NA E -127.2 -34.1 50.0 NA NA HA:P62306:NA
LEU DB:74 c:74 43.0 NA E -115.0 136.2 26.0 NA NA C:P62306:NA
7b0y 21 P62304 100.0 3e-64 EM
 2021-01-13 LEU U:74 g:74 63.0 0.371 E -119.9 -39.1 15.0 0.088 0.283 T:P62306:0.282
7dvq 11 P62304 100.0 3e-64 EM
 2021-03-31 LEU K:74 e:74 65.0 NA E -117.6 -33.4 48.0 NA NA J:P62306:NA
LEU U:74 l:74 65.0 NA E -117.6 -33.7 47.0 NA NA T:P62306:NA
6qdv 34 P62304 100.0 2e-55 EM
 2019-02-20 LEU HA:64 e:74 76.0 0.447 E -121.3 -11.6 25.0 0.147 0.3 IA:P62306:0.3
LEU SA:64 p:74 68.0 0.4 E -127.2 -34.1 14.0 0.082 0.318 TA:P62306:0.318

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62304-f1 1 P62304 100.0 1e-64 LEU A:74 A:74 57.0 0.335 E -113.5 -24.6