Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22405039 . A C CCDS221.1:NM_001039802.1:c.68tAc>tCc_NP_001034891.1:p.23Y>S Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 TYR A:24 A:23 38.0 0.165 H -78.8 -50.3 7.0 0.03 0.135 B:Q9NQU5:0.135
 SO4
HOH
 9.063
2.655
 OH
OH
 O3
O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 TYR B:30 B:23 41.0 0.178 H -60.0 -61.3 41.0 0.178 0.0 HOH
 6.841
 CD1
 O
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 TYR B:26 B:23 53.0 0.23 H -69.2 -37.8 53.0 0.23 0.0 GOL
HOH
 2.563
5.199
 O
O
 O2
O
TYR D:26 D:23 36.0 0.157 H -72.8 -42.3 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 TYR A:23 A:23 41.0 0.178 H -69.8 -46.1 41.0 0.178 0.0 HOH
 2.630
 O
 O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 TYR A:23 A:23 47.0 0.204 H -72.1 -40.1 47.0 0.204 0.0 HOH
 2.755
 O
 O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 TYR C:23 C:23 33.0 0.143 H -70.8 -44.1 33.0 0.143 0.0 GDP
HOH
 9.910
2.831
 N
O
 O6
O
TYR D:23 D:23 35.0 0.152 H -70.5 -38.8 35.0 0.152 0.0 GDP
HOH
 9.979
2.992
 N
O
 N7
O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 TYR C:24 C:23 42.0 0.183 H -82.9 -36.8 42.0 0.183 0.0 GDP
 9.775
 N
 O6
TYR D:24 D:23 36.0 0.157 H -78.4 -35.9 36.0 0.157 0.0 GDP
HOH
 9.910
8.473
 N
N
 N7
O
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 TYR B:26 B:23 40.0 0.174 H -72.5 -45.1 40.0 0.174 0.0
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 TYR A:23 A:23 36.0 0.157 H -61.0 -41.6 36.0 0.157 0.0 GDP
HOH
 9.945
3.978
 N
CE1
 N7
O
TYR B:23 B:23 40.0 0.174 H -62.4 -44.8 40.0 0.174 0.0 GDP
HOH
 9.500
7.355
 N
CE2
 N7
O
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 TYR A:23 A:23 28.0 0.122 H -74.4 -44.7 28.0 0.122 0.0 HOH
 8.254
 CD1
 O
TYR B:23 B:223 28.0 0.122 H -74.2 -48.1 28.0 0.122 0.0 GNH
HOH
 9.960
6.064
 N
O
 N7
O
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 TYR A:23 A:23 38.0 0.165 H -65.6 -49.8 38.0 0.165 0.0 GCP
HOH
 9.901
2.721
 N
O
 O6
O
TYR B:23 B:23 44.0 0.191 H -73.3 -42.9 44.0 0.191 0.0 HOH
 2.766
 OH
 O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 TYR B:25 B:23 29.0 0.126 H -58.6 -47.8 10.0 0.043 0.083 A:Q9BZ29:0.083
 HOH
 2.415
 OH
 O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 TYR B:25 B:23 40.0 0.174 H -59.5 -44.0 14.0 0.061 0.113 A:Q9BZ29:0.113
 HOH
 3.076
 O
 O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 TYR B:25 B:23 33.0 0.143 H -63.6 -48.4 24.0 0.104 0.039 A:Q9BZ29:0.039
 HOH
 2.591
 OH
 O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 TYR A:27 A:23 40.0 0.174 H -64.6 -48.8 3.0 0.013 0.161 C:Q9JK83:0.161
 GNP
HOH
 9.915
2.807
 N
OH
 O6
O
TYR B:27 B:23 39.0 0.17 H -62.4 -48.1 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 TYR A:26 A:23 31.0 0.135 H -70.7 -34.8 31.0 0.135 0.0 HOH
 2.633
 OH
 O
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 TYR B:23 C:23 36.0 0.157 H -67.0 -47.8 NA NA NA
TYR C:23 D:23 55.0 0.239 H -65.4 -38.7 55.0 0.239 0.0 HOH
 3.744
 CA
 O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 TYR B:23 C:23 34.0 0.148 H -92.3 -24.2 NA NA NA
TYR C:23 D:23 48.0 0.209 H -71.2 -31.8 46.0 0.2 0.009 A:Q96BY6:0.009
 HOH
 2.764
 OH
 O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 TYR B:30 B:23 32.0 0.139 H -68.7 -54.7 3.0 0.013 0.126 A:Q96N67:0.126
TYR D:30 D:23 38.0 0.165 H -47.0 -61.6 NA NA NA
TYR F:30 F:23 33.0 0.143 H -67.0 -46.5 NA NA NA
TYR H:30 H:23 32.0 0.139 H -64.8 -45.8 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 TYR B:30 B:23 33.0 0.143 H -63.6 -47.8 3.0 0.013 0.13 A:Q96N67:0.13
TYR D:30 D:23 30.0 0.13 H -52.6 -50.4 NA NA NA
TYR F:30 F:23 31.0 0.135 H -52.5 -57.9 NA NA NA
TYR H:30 H:23 30.0 0.13 H -67.6 -52.8 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 TYR A:23 A:23 24.0 0.104 H -66.9 -46.0 24.0 0.104 0.0 HOH
 2.715
 OH
 O
TYR C:23 C:23 22.0 0.096 H -67.1 -46.2 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 TYR B:23 B:23 31.0 0.135 H -74.1 -36.4 31.0 0.135 0.0 HOH
 2.733
 OH
 O
TYR D:23 D:1023 12.0 0.052 H -66.5 -47.5 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 TYR B:23 B:23 17.0 0.074 H -74.1 -35.8 17.0 0.074 0.0 HOH
 2.483
 OH
 O
TYR D:23 D:1023 11.0 0.048 H -70.2 -39.6 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 TYR B:30 B:23 32.0 0.139 H -59.8 -49.1 1.0 0.004 0.135 A:Q8C147:0.135
 HOH
 2.486
 OH
 O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 TYR A:33 A:23 50.0 0.217 H -66.8 -49.0 4.0 0.017 0.2 B:O30916:0.2
 GDP
HOH
 9.856
2.768
 N
OH
 O6
O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 TYR A:23 A:23 21.0 0.091 I -52.0 -19.2 14.0 0.061 0.03 B:P35465:0.03
 GNP
 2.159
 HB2
 HN1
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 TYR A:25 A:23 15.0 0.065 H -79.4 -42.9 15.0 0.065 0.0 GDP
 9.748
 N
 O6
TYR C:25 C:23 15.0 0.065 H -79.8 -44.3 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 TYR B:25 A:22 48.0 0.209 H -68.5 -49.1 48.0 0.209 0.0 GNP
HOH
 9.994
7.865
 N
N
 O6
O
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 TYR B:25 B:23 51.0 0.222 H -102.8 -53.4 51.0 0.222 0.0
TYR D:25 D:23 42.0 0.183 H -100.8 -53.5 42.0 0.183 0.0
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 TYR A:25 A:23 44.0 0.191 H -79.2 -38.0 44.0 0.191 0.0 HOH
 6.527
 CD1
 O
TYR C:25 C:23 46.0 0.2 H -69.8 -32.5 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 TYR A:23 A:23 30.0 0.13 H -72.8 -42.8 30.0 0.13 0.0 GNP
HOH
 9.938
8.777
 N
N
 O6
O
TYR C:23 C:23 28.0 0.122 H -73.7 -42.2 28.0 0.122 0.0 GNP
HOH
 9.965
8.753
 N
N
 O6
O
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 TYR B:23 B:23 41.0 0.178 H -65.5 -63.6 41.0 0.178 0.0
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 TYR A:27 A:23 30.0 0.13 H -70.5 -40.2 30.0 0.13 0.0 HOH
 2.787
 OH
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 TYR A:23 A:23 40.0 0.174 H -64.1 -48.4 7.0 0.03 0.144 B:Q9UQB8:0.143
 GNP
PE4
HOH
 9.513
4.264
2.421
 H
O
HH
 N7
C5
O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 TYR A:23 A:23 35.0 0.152 H -99.1 -24.0 35.0 0.152 0.0 HOH
 8.740
 N
 O
TYR C:23 C:23 35.0 0.152 H -97.9 -23.4 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 TYR A:25 A:23 37.0 0.161 H -69.2 -40.8 37.0 0.161 0.0 HOH
 3.510
 O
 O
TYR B:25 B:23 38.0 0.165 H -72.5 -33.8 38.0 0.165 0.0 GTP
HOH
 9.963
6.479
 N
N
 O6
O
TYR C:25 C:23 26.0 0.113 H -93.5 -48.2 26.0 0.113 0.0 HOH
 4.414
 O
 O
TYR D:25 D:23 27.0 0.117 H -95.1 -48.6 27.0 0.117 0.0
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 TYR C:23 C:23 44.0 0.191 H -64.2 -52.5 10.0 0.043 0.148 A:O96013:0.148
 GNP
 9.856
 N
 O6
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 TYR B:23 D:523 28.0 0.122 H -55.6 -52.1 28.0 0.122 0.0 GNP
HOH
 9.806
3.567
 N
OH
 O6
O
TYR D:23 E:523 27.0 0.117 H -56.8 -50.4 NA NA NA
TYR F:23 F:523 28.0 0.122 H -55.4 -51.7 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 TYR B:24 B:23 34.0 0.148 H -68.9 -44.0 34.0 0.148 0.0 GDP
HOH
 9.765
9.228
 N
O
 N7
O
5hzh 1 P63000,O49003 81.25 5e-21 X-RAY
 2016-12-21 TYR A:26 A:23 37.0 0.161 H -86.8 -27.0 37.0 0.161 0.0 HOH
 3.047
 OH
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 TYR A:23 A:23 40.0 0.174 H -68.9 -42.2