Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22408233 . G A CCDS221.1:NM_001039802.1:c.124Gtc>Atc_NP_001034891.1:p.42V>I Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 VAL A:43 A:42 31.0 0.2 E -129.4 164.0 1.0 0.006 0.194 B:Q9NQU5:0.194
 HOH
 3.450
 C
 O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 VAL B:49 B:42 41.0 0.265 E -160.8 144.8 41.0 0.265 0.0
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 VAL B:45 B:42 50.0 0.323 E -147.1 148.0 50.0 0.323 0.0 GOL
HOH
 8.381
3.675
 CG1
CB
 O2
O
VAL D:45 D:42 31.0 0.2 E -130.2 141.5 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 VAL A:42 A:42 35.0 0.226 E -115.0 123.6 35.0 0.226 0.0 HOH
 5.811
 CG1
 O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 VAL A:42 A:42 31.0 0.2 E -127.3 122.7 31.0 0.2 0.0 HOH
 3.799
 CA
 O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 VAL C:42 C:42 35.0 0.226 E -144.4 146.0 35.0 0.226 0.0 HOH
 3.351
 CG2
 O
VAL D:42 D:42 35.0 0.226 E -136.7 149.7 35.0 0.226 0.0 HOH
 3.048
 CG2
 O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 VAL C:43 C:42 37.0 0.239 E -128.7 147.4 37.0 0.239 0.0 HOH
 6.794
 C
 O
VAL D:43 D:42 44.0 0.284 E -131.9 145.0 44.0 0.284 0.0 SO4
HOH
 9.781
7.153
 CG1
O
 O4
O
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 VAL B:45 B:42 28.0 0.181 E -132.7 120.4 28.0 0.181 0.0
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 VAL A:42 A:42 39.0 0.252 E -148.4 128.3 39.0 0.252 0.0 HOH
 3.290
 CG2
 O
VAL B:42 B:42 49.0 0.316 E -67.5 137.6 49.0 0.316 0.0 HOH
 4.241
 N
 O
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 VAL A:42 A:42 35.0 0.226 E -122.6 147.5 35.0 0.226 0.0 HOH
 7.987
 N
 O
VAL B:42 B:242 35.0 0.226 E -142.6 143.1 35.0 0.226 0.0 HOH
 9.496
 CG1
 O
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 VAL A:42 A:42 32.0 0.206 E -142.0 136.4 32.0 0.206 0.0 HOH
 3.322
 CG1
 O
VAL B:42 B:42 31.0 0.2 E -152.3 145.1 31.0 0.2 0.0 HOH
 5.616
 CG1
 O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 VAL B:44 B:42 21.0 0.135 E -147.3 142.6 21.0 0.135 0.0 HOH
 3.564
 CA
 O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 VAL B:44 B:42 20.0 0.129 E -144.8 140.2 20.0 0.129 0.0 HOH
 4.795
 CG2
 O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 VAL B:44 B:42 27.0 0.174 E -133.2 144.1 27.0 0.174 0.0 HOH
 3.940
 CG2
 O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 VAL A:46 A:42 35.0 0.226 E -138.8 166.1 2.0 0.013 0.213 C:Q9JK83:0.213
 HOH
 4.765
 O
 O
VAL B:46 B:42 36.0 0.232 E -142.7 155.8 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 VAL A:45 A:42 43.0 0.277 E -142.9 134.6 43.0 0.277 0.0 HOH
 4.152
 C
 O
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 VAL B:42 C:42 18.0 0.116 E -140.6 141.6 NA NA NA
VAL C:42 D:42 23.0 0.148 E -141.5 147.3 23.0 0.148 0.0 HOH
 7.926
 O
 O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 VAL B:42 C:42 14.0 0.09 E -133.0 139.9 NA NA NA
VAL C:42 D:42 38.0 0.245 E -147.1 143.7 26.0 0.168 0.077 A:Q96BY6:0.077
 HOH
 7.284
 CG1
 O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 VAL B:49 B:42 19.0 0.123 E -158.0 115.9 7.0 0.045 0.078 A:Q96N67:0.077
VAL D:49 D:42 25.0 0.161 E -160.1 149.6 NA NA NA
VAL F:49 F:42 19.0 0.123 E -116.1 145.8 NA NA NA
VAL H:49 H:42 20.0 0.129 E -150.3 149.2 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 VAL B:49 B:42 17.0 0.11 E -155.4 141.2 8.0 0.052 0.058 A:Q96N67:0.058
VAL D:49 D:42 24.0 0.155 E -160.4 151.0 NA NA NA
VAL F:49 F:42 26.0 0.168 E -162.5 144.7 NA NA NA
VAL H:49 H:42 21.0 0.135 E -161.4 149.7 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 VAL A:42 A:42 29.0 0.187 E -133.0 136.3 29.0 0.187 0.0 HOH
 3.720
 CA
 O
VAL C:42 C:42 28.0 0.181 E -133.2 136.2 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 VAL B:42 B:42 30.0 0.194 E -115.3 118.0 30.0 0.194 0.0 HOH
 4.100
 CG2
 O
VAL D:42 D:1042 29.0 0.187 E -124.5 127.2 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 VAL B:42 B:42 28.0 0.181 E -107.2 121.2 28.0 0.181 0.0 HOH
 4.130
 CG2
 O
VAL D:42 D:1042 20.0 0.129 E -120.0 124.3 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 VAL B:49 B:42 19.0 0.123 E -146.6 139.1 6.0 0.039 0.084 A:Q8C147:0.084
 HOH
 3.765
 CG2
 O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 VAL A:52 A:42 51.0 0.329 E -145.9 156.1 2.0 0.013 0.316 B:O30916:0.316
 HOH
 3.139
 CG2
 O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 VAL A:42 A:42 28.0 0.181 B -162.2 164.2 5.0 0.032 0.149 B:P35465:0.148
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 VAL A:44 A:42 23.0 0.148 E -119.8 152.5 23.0 0.148 0.0
VAL C:44 C:42 23.0 0.148 E -121.0 152.3 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 VAL B:44 A:41 35.0 0.226 E -141.5 149.1 35.0 0.226 0.0
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 VAL B:44 B:42 52.0 0.335 E -137.5 134.6 52.0 0.335 0.0
VAL D:44 D:42 45.0 0.29 E -138.1 133.0 45.0 0.29 0.0
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 VAL A:44 A:42 33.0 0.213 E -93.9 118.8 33.0 0.213 0.0 HOH
 3.501
 C
 O
VAL C:44 C:42 35.0 0.226 E -114.1 136.9 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 VAL A:42 A:42 29.0 0.187 E -141.5 155.7 29.0 0.187 0.0
VAL C:42 C:42 28.0 0.181 E -141.6 155.9 28.0 0.181 0.0
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 VAL B:42 B:42 35.0 0.226 E -104.3 178.2 35.0 0.226 0.0
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 VAL A:46 A:42 40.0 0.258 E -141.9 148.0 38.0 0.245 0.013 B:Q9R8E4:0.013
 HOH
 3.983
 CG2
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 VAL A:42 A:42 34.0 0.219 E -134.8 164.7 2.0 0.013 0.206 B:Q9UQB8:0.206
 PE4
HOH
 5.552
4.629
 HG11
O
 C5
O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 VAL A:42 A:42 28.0 0.181 E -137.0 138.4 28.0 0.181 0.0 HOH
 5.797
 N
 O
VAL C:42 C:42 26.0 0.168 E -136.1 139.1 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 VAL A:44 A:42 41.0 0.265 E -142.3 150.4 41.0 0.265 0.0 HOH
 3.531
 CG1
 O
VAL B:44 B:42 43.0 0.277 E -143.9 149.6 43.0 0.277 0.0 HOH
 4.425
 N
 O
VAL C:44 C:42 29.0 0.187 E -151.1 126.3 29.0 0.187 0.0 HOH
 6.120
 CG2
 O
VAL D:44 D:42 28.0 0.181 E -148.6 122.4 28.0 0.181 0.0
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 VAL C:42 C:42 32.0 0.206 E -136.3 160.3 1.0 0.006 0.2 A:O96013:0.2
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 VAL B:42 D:542 11.0 NA E -123.8 102.6 11.0 NA NA HOH
 2.948
 CA
 O
VAL D:42 E:542 12.0 NA E -124.5 101.5 NA NA NA
VAL F:42 F:542 12.0 NA E -124.9 104.1 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 VAL B:43 B:42 36.0 0.232 E -105.7 129.8 36.0 0.232 0.0 HOH
 8.824
 CA
 O
5hzh 1 P63000,O49003 81.25 5e-21 X-RAY
 2016-12-21 ALA A:45 A:42 23.0 0.2 E -126.5 147.3 23.0 0.2 0.0 HOH
 8.944
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 VAL A:42 A:42 30.0 0.194 E -130.2 146.0