Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22408246 . T A CCDS221.1:NM_001039802.1:c.137aTt>aAt_NP_001034891.1:p.46I>N Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 ILE A:47 A:46 55.0 0.314 E -121.5 119.4 33.0 0.189 0.125 B:Q9NQU5:0.126
 CL
SO4
SO4
HOH
 9.145
4.851
9.020
7.733
 CD1
C
N
CG1
 CL
O2
O1
O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 ILE B:53 B:46 38.0 0.217 E -109.1 142.4 38.0 0.217 0.0 HOH
 8.436
 CD1
 O
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 ILE B:49 B:46 62.0 0.354 E -147.3 131.3 62.0 0.354 0.0 HOH
 4.916
 O
 O
ILE D:49 D:46 31.0 0.177 E -121.8 126.3 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 ILE A:46 A:46 43.0 0.246 E -115.6 120.7 43.0 0.246 0.0 HOH
 3.641
 C
 O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 ILE A:46 A:46 46.0 0.263 E -116.1 123.4 46.0 0.263 0.0 HOH
 3.854
 N
 O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 ILE C:46 C:46 41.0 0.234 E -124.3 114.9 41.0 0.234 0.0 HOH
 3.213
 O
 O
ILE D:46 D:46 31.0 0.177 E -121.3 106.9 31.0 0.177 0.0 HOH
 3.466
 C
 O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 ILE C:47 C:46 34.0 0.194 E -139.9 125.7 34.0 0.194 0.0
ILE D:47 D:46 107.0 0.611 S -62.1 129.4 107.0 0.611 0.0
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 ILE B:49 B:46 31.0 0.177 E -127.0 113.2 31.0 0.177 0.0
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 ILE A:46 A:46 36.0 0.206 -29.8 117.2 36.0 0.206 0.0 HOH
 6.785
 O
 O
ILE B:46 B:46 37.0 0.211 -19.4 126.5 37.0 0.211 0.0 HOH
 5.575
 C
 O
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 ILE A:46 A:46 42.0 0.24 E -126.7 117.7 8.0 0.046 0.194 B:P60953:0.194
 HOH
 7.337
 N
 O
ILE B:46 B:246 43.0 0.246 E -128.6 119.6 8.0 0.046 0.2 A:P60953:0.2
 HOH
 6.675
 N
 O
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 ILE A:46 A:46 40.0 0.229 E -130.6 108.4 5.0 0.029 0.2 B:P60953:0.2
 HOH
 4.244
 C
 O
ILE B:46 B:46 40.0 0.229 E -128.3 121.0 5.0 0.029 0.2 A:P60953:0.2
 HOH
 4.018
 N
 O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ILE B:48 B:46 17.0 0.097 E -130.4 136.5 17.0 0.097 0.0 HOH
 3.156
 O
 O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ILE B:48 B:46 25.0 0.143 E -119.6 100.8 25.0 0.143 0.0 HOH
 5.257
 N
 O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ILE B:48 B:46 20.0 0.114 E -125.6 120.4 20.0 0.114 0.0 HOH
 5.413
 N
 O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 ILE A:50 A:46 45.0 0.257 E -123.0 108.7 11.0 0.063 0.194 C:Q9JK83:0.194
 HOH
 3.229
 C
 O
ILE B:50 B:46 44.0 0.251 E -127.2 121.9 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 ILE A:49 A:46 24.0 0.137 E -140.9 131.2 24.0 0.137 0.0 HOH
 3.052
 O
 O
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ILE B:46 C:46 26.0 0.149 E -106.8 88.4 NA NA NA
ILE C:46 D:46 43.0 0.246 E -117.1 99.7 43.0 0.246 0.0 HOH
 4.020
 C
 O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ILE B:46 C:46 36.0 0.206 E -123.3 90.8 NA NA NA
ILE C:46 D:46 46.0 0.263 E -115.4 106.0 46.0 0.263 0.0 HOH
 3.691
 C
 O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ILE B:53 B:46 36.0 0.206 -151.8 94.0 36.0 0.206 0.0
ILE D:53 D:46 47.0 0.269 E -142.3 98.3 NA NA NA
ILE F:53 F:46 34.0 0.194 S -134.2 100.4 NA NA NA
ILE H:53 H:46 47.0 0.269 E -148.8 121.7 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ILE B:53 B:46 27.0 0.154 E -154.1 108.7 27.0 0.154 0.0
ILE D:53 D:46 33.0 0.189 E -134.4 116.9 NA NA NA
ILE F:53 F:46 29.0 0.166 E -146.2 112.0 NA NA NA
ILE H:53 H:46 38.0 0.217 E -147.4 134.3 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 ILE A:46 A:46 22.0 0.126 E -136.1 115.8 22.0 0.126 0.0 HOH
 5.823
 CD1
 O
ILE C:46 C:46 22.0 0.126 E -136.1 115.8 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ILE B:46 B:46 36.0 0.206 E -133.2 119.5 36.0 0.206 0.0 HOH
 8.115
 CD1
 O
ILE D:46 D:1046 36.0 0.206 E -123.1 103.2 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ILE B:46 B:46 36.0 0.206 E -106.8 111.3 36.0 0.206 0.0 HOH
 3.952
 C
 O
ILE D:46 D:1046 32.0 0.183 E -129.0 113.3 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 ILE B:53 B:46 37.0 0.211 E -135.2 124.5 37.0 0.211 0.0 HOH
 3.551
 N
 O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 ILE A:56 A:46 37.0 0.211 E -119.7 108.5 11.0 0.063 0.148 B:O30916:0.149
 HOH
 3.789
 N
 O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 ILE A:46 A:46 49.0 0.28 S -87.3 107.1 26.0 0.149 0.131 B:P35465:0.131
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 ILE A:48 A:46 47.0 0.269 E -124.2 102.3 47.0 0.269 0.0
ILE C:48 C:46 45.0 0.257 E -124.4 102.9 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ILE B:48 A:45 47.0 0.269 E -127.9 127.2 47.0 0.269 0.0 HOH
 4.062
 C
 O
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ILE B:48 B:46 47.0 NA S -121.1 116.4 47.0 NA NA
ILE D:48 D:46 66.0 0.377 E -127.5 117.0 66.0 0.377 0.0
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 ILE A:48 A:46 38.0 0.217 E -134.4 133.0 38.0 0.217 0.0 HOH
 7.045
 O
 O
ILE C:48 C:46 50.0 0.286 E -102.9 91.6 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 ILE A:46 A:46 64.0 0.366 E -118.4 116.1 64.0 0.366 0.0
ILE C:46 C:46 62.0 0.354 E -118.8 115.8 62.0 0.354 0.0
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 ILE B:46 B:46 64.0 0.366 E -119.3 122.5 58.0 0.331 0.035 A:O96013:0.034
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 ILE A:50 A:46 33.0 0.189 E -146.6 114.1 33.0 0.189 0.0 HOH
 3.998
 CG1
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 ILE A:46 A:46 43.0 0.246 E -130.0 109.2 18.0 0.103 0.143 B:Q9UQB8:0.143
 HOH
 3.824
 HG21
 O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 ILE A:46 A:46 27.0 0.154 E -130.6 100.0 27.0 0.154 0.0
ILE C:46 C:46 29.0 0.166 E -131.0 99.8 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 ILE A:48 A:46 100.0 0.571 T -82.2 -10.4 100.0 0.571 0.0
ILE B:48 B:46 90.0 0.514 T -79.9 -13.0 90.0 0.514 0.0 HOH
 3.079
 N
 O
ILE C:48 C:46 19.0 0.109 S -137.4 109.1 19.0 0.109 0.0
ILE D:48 D:46 22.0 0.126 S -139.2 111.1 22.0 0.126 0.0
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 ILE C:46 C:46 56.0 0.32 E -121.4 101.1 12.0 0.069 0.251 B:O96013:0.069
A:O96013:0.2
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 ILE B:46 D:546 36.0 NA -158.6 73.4 36.0 NA NA HOH
 3.439
 C
 O
ILE D:46 E:546 37.0 NA -157.7 72.5 NA NA NA
ILE F:46 F:546 36.0 NA -160.1 72.7 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 ILE B:47 B:46 56.0 0.32 E -139.9 121.2 56.0 0.32 0.0
5hzh 1 P63000,O49003 81.25 5e-21 X-RAY
 2016-12-21 VAL A:49 A:46 35.0 0.226 -82.0 109.7 35.0 0.226 0.0 HOH
 7.253
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 ILE A:46 A:46 42.0 0.24 E -125.5 115.8