Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22412944 . A C CCDS221.1:NM_001039802.1:c.191tAt>tCt_NP_001034891.1:p.64Y>S Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 TYR A:65 A:64 63.0 0.274 G -103.6 20.4 33.0 0.143 0.131 B:Q9NQU5:0.13
 GCP
HOH
 7.542
3.526
 CE2
C
 O3G
O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 TYR B:71 B:64 86.0 0.374 G -98.0 13.1 5.0 0.022 0.352 A:Q9H0H5:0.352
 MG
AF3
HOH
 9.970
7.530
2.864
 CD2
CD2
OH
 MG
F2
O
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 TYR B:67 B:64 130.0 0.565 -116.7 83.8 24.0 0.104 0.461 A:Q9QX73:0.461
 HOH
 3.600
 CE1
 O
TYR D:67 D:64 134.0 0.583 -112.2 91.4 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 TYR A:64 A:64 72.0 0.313 G -106.1 16.1 0.0 0.0 0.313 B:Q07960:0.313
 MG
GDP
AF3
HOH
 9.734
9.988
7.514
5.803
 CE2
CD2
CD2
CE2
 MG
O3B
F2
O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 TYR A:64 A:64 70.0 0.304 G -113.1 8.7 0.0 0.0 0.304 B:Q07960:0.304
 MG
AF3
HOH
 9.942
7.685
4.873
 CD2
CD2
N
 MG
F2
O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 TYR C:64 C:64 117.0 0.509 G -98.2 19.4 39.0 0.17 0.339 B:Q06277:0.339
 MG
HOH
 9.788
2.745
 CE2
OH
 MG
O
TYR D:64 D:64 110.0 0.478 G -110.6 15.2 46.0 0.2 0.278 A:Q06277:0.278
 MG
HOH
 9.872
2.635
 CE2
OH
 MG
O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 TYR C:65 C:64 114.0 0.496 G -108.7 25.8 45.0 0.196 0.3 B:Q06277:0.3
 GOL
HOH
 4.237
3.123
 CD1
CA
 C3
O
TYR D:65 D:64 107.0 0.465 G -109.3 21.2 34.0 0.148 0.317 A:Q06277:0.317
 GOL
HOH
 4.140
3.275
 CD2
CE2
 C1
O
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 TYR B:67 B:64 132.0 0.574 -112.3 84.1 22.0 0.096 0.478 A:Q8TCU6:0.478
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 TYR A:64 A:64 71.0 0.309 G -87.7 0.5 71.0 0.309 0.0 MG
GDP
HOH
 8.647
9.396
2.950
 CE2
CE2
OH
 MG
O1B
O
TYR B:64 B:64 108.0 0.47 G -80.1 -1.1 108.0 0.47 0.0 MG
GDP
HOH
 9.237
9.927
4.552
 CE2
CE2
CE2
 MG
O2B
O
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 TYR A:64 A:64 79.0 0.343 G -117.2 16.3 79.0 0.343 0.0 HOH
 4.738
 CB
 O
TYR B:64 B:264 97.0 0.422 G -113.1 2.0 97.0 0.422 0.0
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 TYR A:64 A:64 92.0 0.4 G -105.4 15.8 92.0 0.4 0.0 MG
GCP
HOH
 9.925
7.385
3.000
 CE2
CE2
C
 MG
O2G
O
TYR B:64 B:64 96.0 0.417 S -59.6 11.0 96.0 0.417 0.0 MG
GCP
HOH
 8.809
6.200
4.509
 CE2
CE2
CB
 MG
O2G
O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 TYR B:66 B:64 109.0 0.474 G -125.6 4.0 65.0 0.283 0.191 A:Q9BZ29:0.191
 HOH
 4.451
 OH
 O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 TYR B:66 B:64 118.0 0.513 G -130.9 10.7 98.0 0.426 0.087 A:Q9BZ29:0.087
 HOH
 5.652
 O
 O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 TYR B:66 B:64 106.0 0.461 G -124.1 10.3 104.0 0.452 0.009 A:Q9BZ29:0.009
 GTP
HOH
 6.889
3.989
 CE2
OH
 O2G
O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 TYR A:68 A:64 85.0 0.37 G -100.7 19.2 29.0 0.126 0.244 C:Q9JK83:0.243
 MG
GNP
HOH
 9.118
6.894
3.456
 CD2
CE2
C
 MG
O3G
O
TYR B:68 B:64 85.0 0.37 G -100.7 20.7 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 TYR A:67 A:64 96.0 0.417 G -116.8 33.1 0.0 0.0 0.417 B:P19803:0.417
 MG
HOH
 9.781
3.235
 CD1
CA
 MG
O
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 TYR B:64 C:64 105.0 0.457 G -103.9 2.1 NA NA NA
TYR C:64 D:64 114.0 0.496 G -104.0 13.8 73.0 0.317 0.179 A:Q96BY6:0.178
 HOH
 6.090
 CE1
 O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 TYR B:64 C:64 102.0 0.443 G -95.8 5.5 NA NA NA
TYR C:64 D:64 126.0 0.548 G -101.6 8.4 80.0 0.348 0.2 A:Q96BY6:0.2
 HOH
 6.482
 CE2
 O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 TYR B:71 B:64 126.0 0.548 G -85.4 17.8 87.0 0.378 0.17 A:Q96N67:0.17
TYR D:71 D:64 123.0 0.535 G -104.2 10.2 NA NA NA
TYR F:71 F:64 136.0 0.591 G -73.8 15.2 NA NA NA
TYR H:71 H:64 124.0 0.539 G -88.2 5.4 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 TYR B:71 B:64 118.0 0.513 G -111.6 10.6 76.0 0.33 0.183 A:Q96N67:0.183
TYR D:71 D:64 130.0 0.565 G -106.5 13.9 NA NA NA
TYR F:71 F:64 129.0 0.561 G -91.1 12.1 NA NA NA
TYR H:71 H:64 140.0 0.609 G -107.1 12.7 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 TYR A:64 A:64 136.0 0.591 -128.6 88.4 39.0 0.17 0.421 B:Q15811:0.422
 HOH
 2.545
 OH
 O
TYR C:64 C:64 138.0 0.6 -128.6 88.3 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 TYR B:64 B:64 124.0 0.539 -116.2 91.5 14.0 0.061 0.478 A:Q64096:0.478
 HOH
 2.658
 OH
 O
TYR D:64 D:1064 130.0 0.565 -118.9 87.9 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 TYR B:64 B:64 124.0 0.539 -111.8 95.9 17.0 0.074 0.465 A:Q64096:0.465
 HOH
 2.890
 OH
 O
TYR D:64 D:1064 125.0 0.543 -111.0 92.8 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 TYR B:71 B:64 111.0 0.483 G -97.1 5.5 71.0 0.309 0.174 A:Q8C147:0.174
 HOH
 2.942
 OH
 O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 TYR A:74 A:64 101.0 0.439 G -107.1 3.5 11.0 0.048 0.391 B:O30916:0.391
 MG
HOH
 9.742
5.331
 CE2
CB
 MG
O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 TYR A:64 A:64 29.0 0.126 -102.6 -29.1 22.0 0.096 0.03 B:P35465:0.03
 GNP
MG
HOH
 9.543
8.812
7.123
 HH
HH
HH
 O2G
MG
O
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 TYR A:66 A:64 132.0 0.574 -137.3 103.8 37.0 0.161 0.413 B:Q15811+O49003:0.413
TYR C:66 C:64 132.0 0.574 -137.8 103.1 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 TYR B:66 A:63 74.0 0.322 G -102.5 12.3 5.0 0.022 0.3 A:Q96PY5:0.3
 GNP
HOH
 7.483
4.529
 CD2
CD2
 O3G
O
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 TYR B:66 B:64 82.0 0.357 G -96.5 19.1 12.0 0.052 0.305 A:O95466:0.304
 GNP
MG
 7.428
9.243
 CE2
CE2
 O1G
MG
TYR D:66 D:64 67.0 0.291 G -96.9 16.7 22.0 0.096 0.195 C:O95466:0.196
 GNP
MG
 7.460
9.536
 CE2
CD2
 O2G
MG
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 TYR A:66 A:64 130.0 0.565 -99.3 67.8 8.0 0.035 0.53 B:O52623:0.53
 SO4
HOH
 4.174
2.602
 N
OH
 O2
O
TYR C:66 C:64 132.0 0.574 -98.2 66.9 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 TYR A:64 A:64 85.0 0.37 G -106.0 20.3 5.0 0.022 0.348 B:O08808:0.348
 GNP
MG
HOH
 7.997
9.950
3.417
 CD2
CD2
C
 O1G
MG
O
TYR C:64 C:64 85.0 0.37 G -107.2 19.3 5.0 0.022 0.348 D:O08808:0.348
 GNP
MG
HOH
 7.956
9.930
4.375
 CD2
CD2
CE2
 O1G
MG
O
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 TYR B:64 B:64 55.0 0.239 T -108.9 27.5 55.0 0.239 0.0
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 TYR A:68 A:64 134.0 0.583 -128.7 73.8 31.0 0.135 0.448 B:Q9R8E4:0.448
 HOH
 3.547
 CA
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 TYR A:64 A:64 78.0 0.339 G -102.2 15.7 71.0 0.309 0.03 B:Q9UQB8:0.03
 GNP
MG
HOH
 7.421
9.609
3.806
 HD2
HD2
HB3
 O3G
MG
O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 TYR A:64 A:64 134.0 0.583 -134.3 94.3 34.0 0.148 0.435 B:Q15811:0.435
 HOH
 3.775
 CE1
 O
TYR C:64 C:64 139.0 0.604 -134.6 94.0 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 TYR A:66 A:64 65.0 0.283 G -96.9 19.5 23.0 0.1 0.183 E:Q13576:0.183
 GTP
MG
HOH
 6.771
8.948
3.340
 CE1
CE1
OH
 O3G
MG
O
TYR B:66 B:64 72.0 0.313 G -105.2 17.1 27.0 0.117 0.196 F:Q13576:0.196
 GTP
MG
HOH
 6.894
9.376
3.242
 CE1
CD1
C
 O1G
MG
O
TYR C:66 C:64 103.0 0.448 G -116.4 19.0 1.0 0.004 0.444 E:Q13576:0.443
 GTP
MG
HOH
 7.595
9.901
8.854
 CD2
CD2
CE2
 O3G
MG
O
TYR D:66 D:64 104.0 0.452 G -117.6 24.4 1.0 0.004 0.448 F:Q13576:0.448
 GTP
MG
HOH
 7.601
9.693
5.229
 CE2
CD2
CE2
 O3G
MG
O
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 TYR C:64 C:64 84.0 0.365 G -106.0 28.8 28.0 0.122 0.243 A:O96013:0.243
 GNP
MG
 6.669
9.459
 CD2
CE2
 O3G
MG
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 TYR B:64 D:564 88.0 0.383 G -66.7 -9.8 3.0 0.013 0.37 A:Q07960:0.37
 MG
GNP
HOH
 9.150
6.538
4.496
 CD2
CD2
CD2
 MG
O3G
O
TYR D:64 E:564 90.0 0.391 G -66.4 -9.3 NA NA NA
TYR F:64 F:564 88.0 0.383 G -67.9 -8.3 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 TYR B:65 B:64 105.0 0.457 G -114.1 23.7 5.0 0.022 0.435 A:P18177:0.435
 GDP
MG
SO4
HOH
 9.906
9.377
6.599
7.847
 CE2
CE2
N
CE2
 O1B
MG
O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 TYR A:64 A:64 62.0 0.27 G -103.0 9.1