Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22412949 . A C CCDS221.1:NM_001039802.1:c.196Aga>Cga_NP_001034891.1:p.66R>R Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 ARG A:67 A:66 235.0 1.0 T -77.6 -29.8 235.0 1.0 0.0 HOH
 2.943
 N
 O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 ARG B:73 B:66 237.0 1.0 T -89.3 -25.6 122.0 0.542 0.458 A:Q9H0H5:0.511
 HOH
 3.776
 N
 O
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 ARG B:69 B:66 202.0 0.898 T -92.9 -8.3 55.0 0.244 0.654 A:Q9QX73:0.653
 HOH
 3.155
 CD
 O
ARG D:69 D:66 202.0 0.898 T -99.3 -14.1 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 ARG A:66 A:66 233.0 1.0 T -78.4 -18.8 126.0 0.56 0.44 B:Q07960:0.476
 HOH
 3.059
 NH1
 O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 ARG A:66 A:66 233.0 1.0 T -79.9 -33.8 109.0 0.484 0.516 B:Q07960:0.551
 HOH
 4.211
 N
 O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 ARG C:66 C:66 232.0 1.0 T -70.0 -36.2 83.0 0.369 0.631 B:Q06277:0.662
 HOH
 2.901
 N
 O
ARG D:66 D:66 233.0 1.0 T -84.2 -26.3 116.0 0.516 0.484 A:Q06277:0.52
 HOH
 2.582
 NH1
 O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 ARG C:67 C:66 191.0 0.849 T -78.9 -34.7 73.0 0.324 0.525 B:Q06277:0.524
 GOL
HOH
 7.412
3.334
 C
N
 C1
O
ARG D:67 D:66 235.0 1.0 T -80.7 -37.1 103.0 0.458 0.542 A:Q06277:0.587
 GOL
HOH
 7.572
6.022
 C
C
 C1
O
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 ARG B:69 B:66 165.0 0.733 T -86.2 -24.1 57.0 0.253 0.48 A:Q8TCU6:0.48
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 ARG A:66 A:66 214.0 0.951 T -74.2 -20.2 214.0 0.951 0.0 HOH
 3.970
 O
 O
ARG B:66 B:66 228.0 1.0 T -79.3 -20.0 228.0 1.0 0.0 HOH
 9.284
 O
 O
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 ARG A:66 A:66 203.0 0.902 T -62.3 -49.6 203.0 0.902 0.0 HOH
 3.727
 NH1
 O
ARG B:66 B:266 191.0 0.849 T -70.6 -49.7 191.0 0.849 0.0
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 ARG A:66 A:66 206.0 0.916 T -72.4 -35.3 206.0 0.916 0.0 HOH
 2.775
 N
 O
ARG B:66 B:66 220.0 0.978 T -72.7 -33.3 220.0 0.978 0.0 HOH
 7.859
 C
 O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ARG B:68 B:66 212.0 0.942 T -74.9 -57.9 206.0 0.916 0.026 A:Q9BZ29:0.027
 HOH
 4.670
 N
 O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ARG B:68 B:66 85.0 NA T -76.8 -33.3 85.0 NA NA HOH
 4.631
 N
 O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ARG B:68 B:66 91.0 NA T -75.4 -46.0 91.0 NA NA HOH
 5.117
 N
 O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 ARG A:70 A:66 225.0 1.0 G -48.2 -37.5 204.0 0.907 0.093 C:Q9JK83:0.093
 HOH
 2.793
 NH1
 O
ARG B:70 B:66 235.0 1.0 G -54.9 -33.1 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 ARG A:69 A:66 227.0 1.0 T -99.6 -31.1 9.0 0.04 0.96 B:P19803:0.969
 HOH
 3.104
 N
 O
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ARG B:66 C:66 207.0 0.92 T -78.9 -35.7 NA NA NA
ARG C:66 D:66 98.0 NA T -75.9 -31.3 98.0 NA NA HOH
 6.412
 CA
 O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ARG B:66 C:66 216.0 0.96 T -70.8 -52.0 NA NA NA
ARG C:66 D:66 90.0 NA T -77.7 -39.6 90.0 NA NA HOH
 7.048
 N
 O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ARG B:73 B:66 237.0 1.0 T -68.3 -27.2 237.0 1.0 0.0
ARG D:73 D:66 239.0 1.0 T -70.2 -30.5 NA NA NA
ARG F:73 F:66 234.0 1.0 T -59.0 -45.8 NA NA NA
ARG H:73 H:66 231.0 1.0 G -85.3 -12.8 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ARG B:73 B:66 237.0 1.0 T -77.1 -42.4 237.0 1.0 0.0
ARG D:73 D:66 242.0 1.0 T -75.7 -34.5 NA NA NA
ARG F:73 F:66 223.0 0.991 T -71.3 -43.3 NA NA NA
ARG H:73 H:66 229.0 1.0 T -54.4 -43.6 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 ARG A:66 A:66 162.0 0.72 T -98.1 -8.0 45.0 0.2 0.52 B:Q15811:0.52
 HOH
 5.282
 N
 O
ARG C:66 C:66 160.0 0.711 T -97.9 -8.1 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ARG B:66 B:66 212.0 0.942 T -109.3 -22.6 26.0 0.116 0.826 A:Q64096:0.827
 HOH
 2.720
 NE
 O
ARG D:66 D:1066 211.0 0.938 T -103.4 -19.7 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ARG B:66 B:66 210.0 0.933 T -103.7 -30.2 23.0 0.102 0.831 A:Q64096:0.831
 HOH
 2.635
 NH1
 O
ARG D:66 D:1066 208.0 0.924 T -105.6 -28.5 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 ARG B:73 B:66 231.0 1.0 T -81.2 -36.9 231.0 1.0 0.0 HOH
 2.217
 O
 O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 ARG A:76 A:66 202.0 0.898 T -92.2 -6.3 142.0 0.631 0.267 B:O30916:0.267
 HOH
 7.780
 O
 O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 ARG A:66 A:66 189.0 0.84 S -93.5 -31.5 169.0 0.751 0.089 B:P35465:0.089
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 ARG A:68 A:66 171.0 0.76 T -101.4 -10.8 54.0 0.24 0.52 B:Q15811+O49003:0.52
ARG C:68 C:66 159.0 0.707 T -102.5 -8.1 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ARG B:68 A:65 236.0 1.0 T -100.9 -7.4 21.0 0.093 0.907 A:Q96PY5:0.956
 HOH
 2.988
 NE
 O
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ARG B:68 B:66 234.0 1.0 T -90.9 -14.0 17.0 0.076 0.924 A:O95466:0.964
ARG D:68 D:66 236.0 1.0 T -87.7 -20.3 14.0 0.062 0.938 C:O95466:0.987
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 ARG A:68 A:66 207.0 0.92 T -85.7 -22.6 103.0 0.458 0.462 B:O52623:0.462
 SO4
HOH
 6.425
4.486
 N
CD
 O2
O
ARG C:68 C:66 211.0 0.938 T -76.1 -17.6 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 ARG A:66 A:66 234.0 1.0 T -85.9 -14.1 10.0 0.044 0.956 B:O08808:0.996
 HOH
 2.863
 N
 O
ARG C:66 C:66 234.0 1.0 T -86.2 -13.3 9.0 0.04 0.96 D:O08808:1.0
 HOH
 3.617
 NH2
 O
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 ARG B:66 B:66 234.0 1.0 T -96.5 -15.4 234.0 1.0 0.0
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 ARG A:70 A:66 199.0 0.884 T -86.4 -19.3 60.0 0.267 0.617 B:Q9R8E4:0.618
 HOH
 2.537
 NH2
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 ARG A:66 A:66 237.0 1.0 T -80.8 -28.6 237.0 1.0 0.0 HOH
 4.134
 HG3
 O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 ARG A:66 A:66 164.0 0.729 T -95.5 -15.4 78.0 0.347 0.382 B:Q15811:0.382
 HOH
 2.627
 O
 O
ARG C:66 C:66 163.0 0.724 T -96.0 -15.8 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 ARG A:68 A:66 231.0 1.0 T -82.3 -22.5 74.0 0.329 0.671 F:Q13576:0.556
B:A0A024RAE4:0.156
 HOH
 6.456
 NH2
 O
ARG B:68 B:66 240.0 1.0 T -63.2 -37.1 100.0 0.444 0.556 E:Q13576:0.476
A:A0A024RAE4:0.156
 HOH
 2.767
 N
 O
ARG C:68 C:66 239.0 1.0 T -64.9 -26.7 112.0 0.498 0.502 E:Q13576:0.564
 HOH
 3.068
 NH2
 O
ARG D:68 D:66 238.0 1.0 T -60.7 -33.8 117.0 0.52 0.48 F:Q13576:0.538
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 ARG C:66 C:66 223.0 0.991 T -47.5 -32.5 142.0 0.631 0.36 A:O96013:0.36
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 ARG B:66 D:566 208.0 0.924 T -84.2 -57.2 170.0 0.756 0.168 A:Q07960:0.169
 HOH
 2.599
 NH1
 O
ARG D:66 E:566 209.0 0.929 T -84.3 -57.8 NA NA NA
ARG F:66 F:566 207.0 0.92 T -84.7 -56.6 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 ARG B:67 B:66 231.0 1.0 T -105.1 -24.4 93.0 0.413 0.587 A:P18177:0.613

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 ARG A:66 A:66 234.0 1.0 T -83.7 -24.6