Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22412956 . G A CCDS221.1:NM_001039802.1:c.203cGa>cAa_NP_001034891.1:p.68R>Q Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 ARG A:69 A:68 11.0 0.049 G -54.5 -50.4 4.0 0.018 0.031 B:Q9NQU5:0.031
 SO4
GCP
HOH
 7.940
7.836
2.667
 O
NE
O
 O2
O2G
O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 ARG B:75 B:68 7.0 0.031 G -60.9 -46.8 7.0 0.031 0.0 GDP
AF3
HOH
 9.952
7.321
4.381
 NE
NE
NH1
 O1B
F2
O
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 ARG B:71 B:68 12.0 0.053 G -50.7 -46.0 12.0 0.053 0.0 HOH
 2.689
 O
 O
ARG D:71 D:68 23.0 0.102 G -62.4 -33.3 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 ARG A:68 A:68 0.0 0.0 G -49.8 -44.0 0.0 0.0 0.0 AF3
HOH
 7.202
3.434
 NH2
NE
 F2
O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 ARG A:68 A:68 0.0 0.0 G -53.6 -43.0 0.0 0.0 0.0 AF3
HOH
 7.428
3.366
 NH2
NE
 F2
O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 ARG C:68 C:68 10.0 0.044 G -39.4 -48.2 10.0 0.044 0.0 HOH
 3.195
 O
 O
ARG D:68 D:68 10.0 0.044 G -40.4 -50.1 10.0 0.044 0.0 HOH
 3.320
 O
 O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 ARG C:69 C:68 6.0 0.027 G -55.2 -44.8 6.0 0.027 0.0 GOL
HOH
 3.942
3.897
 CA
NH2
 C1
O
ARG D:69 D:68 7.0 0.031 G -52.6 -47.2 7.0 0.031 0.0 GOL
HOH
 3.817
3.451
 CA
O
 O1
O
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 ARG B:71 B:68 14.0 0.062 G -53.8 -45.6 14.0 0.062 0.0
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 ARG A:68 A:68 12.0 0.053 G -29.3 -54.3 12.0 0.053 0.0 HOH
 3.676
 CA
 O
ARG B:68 B:68 15.0 0.067 G -41.8 -43.3 15.0 0.067 0.0 HOH
 8.069
 O
 O
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 ARG A:68 A:68 10.0 0.044 G -32.6 -51.5 10.0 0.044 0.0 HOH
 3.474
 CA
 O
ARG B:68 B:268 9.0 0.04 G -18.1 -59.6 9.0 0.04 0.0
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 ARG A:68 A:68 10.0 0.044 G -50.3 -50.2 10.0 0.044 0.0 GCP
HOH
 7.617
3.850
 NH1
CD
 O3G
O
ARG B:68 B:68 13.0 0.058 G -50.9 -45.1 13.0 0.058 0.0 GCP
HOH
 7.480
3.845
 NH1
CG
 O3G
O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ARG B:70 B:68 11.0 0.049 G -51.8 -49.0 0.0 0.0 0.049 A:Q9BZ29:0.049
 HOH
 3.846
 NE
 O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ARG B:70 B:68 15.0 0.067 G -43.2 -51.8 15.0 0.067 0.0 HOH
 3.980
 NH1
 O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ARG B:70 B:68 12.0 0.053 G -51.9 -48.9 12.0 0.053 0.0 GTP
HOH
 7.712
3.587
 NE
NE
 O1G
O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 ARG A:72 A:68 5.0 0.022 G -53.0 -47.5 5.0 0.022 0.0 GNP
HOH
 7.592
3.205
 NH2
O
 O1G
O
ARG B:72 B:68 5.0 0.022 G -51.8 -52.3 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 ARG A:71 A:68 12.0 0.053 G -44.8 -49.9 0.0 0.0 0.053 B:P19803:0.053
 MG
HOH
 9.626
2.703
 CD
O
 MG
O
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ARG B:68 C:68 7.0 0.031 G -55.4 -46.2 NA NA NA
ARG C:68 D:68 9.0 0.04 G -53.2 -44.7 9.0 0.04 0.0 HOH
 4.002
 CD
 O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ARG B:68 C:68 13.0 0.058 G -53.6 -39.7 NA NA NA
ARG C:68 D:68 13.0 0.058 G -58.6 -43.8 13.0 0.058 0.0 HOH
 4.365
 CD
 O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ARG B:75 B:68 14.0 0.062 G -61.4 -51.5 14.0 0.062 0.0
ARG D:75 D:68 14.0 0.062 G -37.0 -46.3 NA NA NA
ARG F:75 F:68 13.0 0.058 G -68.9 -61.3 NA NA NA
ARG H:75 H:68 14.0 0.062 G -39.9 -51.4 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ARG B:75 B:68 13.0 0.058 G -50.4 -52.5 11.0 0.049 0.009 A:Q96N67:0.009
ARG D:75 D:68 16.0 0.071 G -38.4 -49.2 NA NA NA
ARG F:75 F:68 13.0 0.058 G -58.7 -54.8 NA NA NA
ARG H:75 H:68 12.0 0.053 G -59.8 -57.4 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 ARG A:68 A:68 18.0 0.08 G -53.0 -49.0 18.0 0.08 0.0 HOH
 2.682
 O
 O
ARG C:68 C:68 17.0 0.076 G -53.0 -48.9 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ARG B:68 B:68 16.0 0.071 G -51.5 -47.2 16.0 0.071 0.0 HOH
 2.496
 NH2
 O
ARG D:68 D:1068 16.0 0.071 G -48.7 -51.3 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ARG B:68 B:68 19.0 0.084 G -47.2 -51.9 19.0 0.084 0.0 HOH
 2.716
 NH2
 O
ARG D:68 D:1068 19.0 0.084 G -45.2 -50.5 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 ARG B:75 B:68 11.0 0.049 G -59.5 -48.8 11.0 0.049 0.0 HOH
 3.479
 O
 O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 ARG A:78 A:68 13.0 0.058 G -49.4 -44.0 2.0 0.009 0.049 B:O30916:0.049
 HOH
 3.868
 CA
 O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 ARG A:68 A:68 96.0 0.427 S -85.3 -46.3 96.0 0.427 0.0
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 ARG A:70 A:68 18.0 0.08 G -53.9 -49.1 18.0 0.08 0.0
ARG C:70 C:68 16.0 0.071 G -53.5 -48.4 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ARG B:70 A:67 6.0 0.027 G -52.4 -35.7 6.0 0.027 0.0 GNP
HOH
 7.616
3.636
 NH1
CD
 O1G
O
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ARG B:70 B:68 4.0 0.018 G -52.2 -42.7 4.0 0.018 0.0 GNP
MG
 7.467
9.966
 NH1
NH1
 O3G
MG
ARG D:70 D:68 7.0 0.031 G -50.2 -40.9 6.0 0.027 0.004 C:O95466:0.004
 GNP
MG
 7.732
9.921
 NH1
CD
 O3G
MG
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 ARG A:70 A:68 6.0 0.027 G -47.6 -47.3 6.0 0.027 0.0 SO4
HOH
 2.524
2.803
 NH2
O
 O2
O
ARG C:70 C:68 4.0 0.018 G -52.5 -39.7 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 ARG A:68 A:68 4.0 0.018 G -48.7 -48.0 4.0 0.018 0.0 GNP
MG
HOH
 7.828
9.959
3.574
 NH1
CD
CD
 O3G
MG
O
ARG C:68 C:68 3.0 0.013 G -47.7 -48.3 3.0 0.013 0.0 GNP
MG
HOH
 7.792
9.938
3.565
 NH1
CD
CD
 O3G
MG
O
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 ARG B:68 B:68 8.0 0.036 S -68.3 -56.2 8.0 0.036 0.0
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 ARG A:72 A:68 13.0 0.058 G -46.6 -47.3 13.0 0.058 0.0 HOH
 2.416
 NH2
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 ARG A:68 A:68 0.0 0.0 G -48.8 -48.7 0.0 0.0 0.0 GNP
MG
HOH
 6.943
9.374
3.013
 HH21
HE
HG3
 O1G
MG
O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 ARG A:68 A:68 32.0 0.142 G -45.8 -50.8 32.0 0.142 0.0 HOH
 5.957
 NH1
 O
ARG C:68 C:68 33.0 0.147 G -45.7 -50.9 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 ARG A:70 A:68 2.0 0.009 G -54.3 -47.8 2.0 0.009 0.0 GTP
MG
HOH
 7.476
9.057
3.679
 NE
NE
CA
 O1G
MG
O
ARG B:70 B:68 2.0 0.009 G -46.2 -45.4 2.0 0.009 0.0 GTP
MG
HOH
 7.354
9.016
3.718
 NH2
NE
NE
 O2G
MG
O
ARG C:70 C:68 5.0 0.022 G -45.9 -47.6 5.0 0.022 0.0 GTP
MG
HOH
 7.392
9.239
5.765
 NE
NE
O
 O2G
MG
O
ARG D:70 D:68 4.0 0.018 G -51.4 -39.6 4.0 0.018 0.0 GTP
MG
 7.578
8.893
 NE
NE
 O2G
MG
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 ARG C:68 C:68 5.0 0.022 G -47.2 -51.8 5.0 0.022 0.0 GNP
 7.409
 NE
 O2G
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 ARG B:68 D:568 0.0 0.0 S -68.6 -41.4 0.0 0.0 0.0 MG
GNP
HOH
 9.917
7.407
5.377
 NE
NH2
NH1
 MG
O1G
O
ARG D:68 E:568 0.0 0.0 S -68.1 -41.3 NA NA NA
ARG F:68 F:568 0.0 0.0 G -68.6 -41.1 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 ARG B:69 B:68 11.0 0.049 G -58.3 -51.2 2.0 0.009 0.04 A:P18177:0.04
 SO4
HOH
 6.796
9.384
 NH2
NE
 O3
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 ARG A:68 A:68 8.0 0.036 G -52.8 -44.3