Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22412980 . A C CCDS221.1:NM_001039802.1:c.227gAt>gCt_NP_001034891.1:p.76D>A Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 ASP A:77 A:76 61.0 0.407 S -93.5 -30.5 61.0 0.407 0.0 CL
SO4
HOH
 4.264
8.960
8.600
 OD1
OD2
O
 CL
O4
O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 ASP B:83 B:76 13.0 0.087 S -96.8 -22.2 13.0 0.087 0.0 HOH
 2.876
 OD2
 O
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 ASP B:79 B:76 7.0 0.047 S -100.0 -23.3 7.0 0.047 0.0 HOH
 2.801
 O
 O
ASP D:79 D:76 26.0 0.173 S -106.1 -22.3 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 ASP A:76 A:76 17.0 0.113 S -97.7 -25.7 17.0 0.113 0.0 HOH
 2.726
 O
 O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 ASP A:76 A:76 20.0 0.133 S -101.7 -24.8 20.0 0.133 0.0 HOH
 2.860
 O
 O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 ASP C:76 C:76 63.0 0.42 -99.7 -30.1 63.0 0.42 0.0 HOH
 2.974
 O
 O
ASP D:76 D:76 62.0 0.413 -99.7 -23.0 62.0 0.413 0.0 HOH
 2.770
 O
 O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 ASP C:77 C:76 32.0 0.213 -97.0 -28.3 32.0 0.213 0.0 HOH
 8.111
 N
 O
ASP D:77 D:76 53.0 0.353 S -97.8 -24.6 53.0 0.353 0.0 HOH
 6.750
 N
 O
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 ASP B:79 B:76 70.0 0.467 S -94.4 -33.5 70.0 0.467 0.0
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 ASP A:76 A:76 6.0 0.04 -111.0 -36.0 6.0 0.04 0.0 HOH
 4.741
 OD1
 O
ASP B:76 B:76 17.0 0.113 S -103.6 -34.8 17.0 0.113 0.0 HOH
 3.392
 OD2
 O
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 ASP A:76 A:76 1.0 0.007 S -97.7 -27.8 1.0 0.007 0.0 HOH
 3.043
 O
 O
ASP B:76 B:276 2.0 0.013 S -96.8 -25.1 2.0 0.013 0.0 HOH
 8.918
 OD2
 O
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 ASP A:76 A:76 2.0 0.013 -91.0 -37.3 2.0 0.013 0.0 HOH
 2.245
 O
 O
ASP B:76 B:76 16.0 0.107 -87.4 -24.2 16.0 0.107 0.0 HOH
 2.345
 O
 O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ASP B:78 B:76 70.0 0.467 S -92.4 -24.0 67.0 0.447 0.02 A:Q9BZ29:0.02
 HOH
 5.574
 N
 O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ASP B:78 B:76 59.0 0.393 S -104.4 -19.7 57.0 0.38 0.013 A:Q9BZ29:0.013
 HOH
 5.411
 N
 O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ASP B:78 B:76 61.0 0.407 S -96.1 -23.8 58.0 0.387 0.02 A:Q9BZ29:0.02
 HOH
 2.869
 OD2
 O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 ASP A:80 A:76 10.0 0.067 S -97.8 -32.8 10.0 0.067 0.0 HOH
 2.458
 O
 O
ASP B:80 B:76 11.0 0.073 S -96.4 -33.6 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 ASP A:79 A:76 58.0 0.387 S -98.0 -31.4 58.0 0.387 0.0 HOH
 2.823
 O
 O
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ASP B:76 C:76 66.0 0.44 S -97.9 -25.5 NA NA NA
ASP C:76 D:76 50.0 0.333 S -90.2 -30.5 49.0 0.327 0.006 A:Q96BY6:0.007
 HOH
 4.642
 OD1
 O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ASP B:76 C:76 69.0 0.46 S -102.8 -20.9 NA NA NA
ASP C:76 D:76 50.0 0.333 S -96.5 -27.7 50.0 0.333 0.0 HOH
 3.974
 OD1
 O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ASP B:83 B:76 69.0 0.46 -99.7 -22.3 48.0 0.32 0.14 A:Q96N67:0.14
ASP D:83 D:76 62.0 0.413 -101.9 -30.4 NA NA NA
ASP F:83 F:76 68.0 0.453 -101.5 -41.6 NA NA NA
ASP H:83 H:76 60.0 0.4 -110.1 -26.7 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ASP B:83 B:76 65.0 0.433 -104.7 -25.5 44.0 0.293 0.14 A:Q96N67:0.14
ASP D:83 D:76 60.0 0.4 -97.5 -34.0 NA NA NA
ASP F:83 F:76 62.0 0.413 -97.8 -26.4 NA NA NA
ASP H:83 H:76 67.0 0.447 -112.0 -29.0 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 ASP A:76 A:76 64.0 0.427 S -99.1 -23.1 64.0 0.427 0.0 HOH
 7.842
 OD2
 O
ASP C:76 C:76 68.0 0.453 S -99.2 -22.8 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ASP B:76 B:76 63.0 0.42 S -94.8 -25.2 63.0 0.42 0.0 HOH
 2.685
 OD2
 O
ASP D:76 D:1076 71.0 0.473 S -89.8 -27.3 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ASP B:76 B:76 59.0 0.393 S -95.9 -24.4 59.0 0.393 0.0 HOH
 7.561
 OD1
 O
ASP D:76 D:1076 66.0 0.44 S -95.0 -23.9 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 ASP B:83 B:76 71.0 0.473 S -85.2 -35.3 51.0 0.34 0.133 A:Q8C147:0.133
 HOH
 2.713
 O
 O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 ASP A:86 A:76 60.0 0.4 S -100.2 -25.5 45.0 0.3 0.1 B:O30916:0.1
 HOH
 2.843
 O
 O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 ASP A:76 A:76 20.0 0.133 S 168.0 -165.4 20.0 0.133 0.0
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 ASP A:78 A:76 66.0 0.44 S -94.0 -29.4 66.0 0.44 0.0
ASP C:78 C:76 66.0 0.44 S -93.2 -29.2 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ASP B:78 A:75 58.0 0.387 S -96.4 -29.5 58.0 0.387 0.0 HOH
 8.273
 N
 O
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ASP B:78 B:76 65.0 0.433 S -91.0 -29.7 65.0 0.433 0.0
ASP D:78 D:76 62.0 0.413 S -91.4 -29.5 62.0 0.413 0.0
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 ASP A:78 A:76 62.0 0.413 S -91.8 -21.6 62.0 0.413 0.0 SO4
HOH
 7.519
2.853
 CA
O
 O2
O
ASP C:78 C:76 61.0 0.407 S -99.3 -25.1 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 ASP A:76 A:76 71.0 0.473 S -98.1 -30.1 71.0 0.473 0.0 HOH
 8.184
 N
 O
ASP C:76 C:76 71.0 0.473 S -97.0 -30.0 71.0 0.473 0.0 HOH
 8.366
 N
 O
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 ASP B:76 B:76 63.0 0.42 S -74.6 -26.8 63.0 0.42 0.0
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 ASP A:80 A:76 66.0 0.44 S -94.2 -30.2 66.0 0.44 0.0 HOH
 2.728
 O
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 ASP A:76 A:76 59.0 0.393 S -97.6 -30.0 59.0 0.393 0.0 MG
HOH
 4.024
2.534
 OD2
OD2
 MG
O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 ASP A:76 A:76 67.0 0.447 S -95.1 -24.8 67.0 0.447 0.0 HOH
 5.255
 N
 O
ASP C:76 C:76 67.0 0.447 S -95.6 -23.9 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 ASP A:78 A:76 59.0 0.393 S -92.7 -35.7 59.0 0.393 0.0 HOH
 2.745
 O
 O
ASP B:78 B:76 59.0 0.393 S -95.4 -32.1 59.0 0.393 0.0
ASP C:78 C:76 62.0 0.413 S -80.6 -49.2 62.0 0.413 0.0
ASP D:78 D:76 58.0 0.387 S -84.8 -45.7 58.0 0.387 0.0
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 ASP C:76 C:76 63.0 0.42 -91.5 -28.5 63.0 0.42 0.0 HOH
 8.173
 N
 O
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 ASP B:76 D:576 76.0 0.507 -111.3 22.4 76.0 0.507 0.0 HOH
 7.327
 N
 O
ASP D:76 E:576 75.0 0.5 -110.0 23.5 NA NA NA
ASP F:76 F:576 76.0 0.507 -109.6 22.6 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 ASP B:77 B:76 68.0 0.453 -103.8 -24.4 68.0 0.453 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 ASP A:76 A:76 67.0 0.447 S -87.7 -33.3