Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22412995 . G A CCDS221.1:NM_001039802.1:c.242tGt>tAt_NP_001034891.1:p.81C>Y Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 CYS A:82 A:81 0.0 0.0 E -101.6 145.9 0.0 0.0 0.0 GCP
HOH
 6.887
2.836
 CB
O
 O1B
O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 CYS B:88 B:81 0.0 0.0 E -98.8 143.9 0.0 0.0 0.0 GDP
AF3
HOH
 6.818
8.756
2.843
 CB
O
O
 O1B
F2
O
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 CYS B:84 B:81 0.0 0.0 E -99.4 138.2 0.0 0.0 0.0 SO4
HOH
 6.041
2.905
 CB
O
 O4
O
CYS D:84 D:81 1.0 0.007 E -104.9 140.4 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 CYS A:81 A:81 0.0 0.0 E -98.9 150.3 0.0 0.0 0.0 GDP
AF3
HOH
 6.885
8.869
2.782
 CB
O
O
 O1B
F2
O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 CYS A:81 A:81 0.0 0.0 E -103.1 150.8 0.0 0.0 0.0 GDP
AF3
HOH
 6.841
9.069
2.881
 CB
O
O
 O1B
F2
O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 CYS C:81 C:81 0.0 0.0 E -102.4 139.0 0.0 0.0 0.0 GDP
HOH
 6.972
2.812
 CB
O
 O3B
O
CYS D:81 D:81 1.0 0.007 E -100.7 146.7 1.0 0.007 0.0 GDP
HOH
 7.092
2.903
 CB
O
 O3B
O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 CYS C:82 C:81 0.0 0.0 E -98.8 146.3 0.0 0.0 0.0 GDP
HOH
 6.785
2.554
 CB
O
 O3B
O
CYS D:82 D:81 0.0 0.0 E -104.1 139.7 0.0 0.0 0.0 GDP
HOH
 6.815
2.252
 CB
O
 O3B
O
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 CYS B:84 B:81 1.0 0.007 E -100.0 153.0 1.0 0.007 0.0
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 CYS A:81 A:81 0.0 0.0 E -97.0 143.1 0.0 0.0 0.0 GDP
HOH
 6.565
7.404
 CB
CB
 O3B
O
CYS B:81 B:81 0.0 0.0 E -95.4 147.0 0.0 0.0 0.0 GDP
HOH
 6.929
7.381
 CB
CB
 O1B
O
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 CYS A:81 A:81 0.0 0.0 E -103.5 148.6 0.0 0.0 0.0 MG
GDP
HOH
 9.742
6.861
2.828
 SG
CB
O
 MG
O2B
O
CYS B:81 B:281 0.0 0.0 E -103.1 147.1 0.0 0.0 0.0 GNH
 7.311
 CB
 O2B
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 CYS A:81 A:81 1.0 0.007 E -103.5 147.4 1.0 0.007 0.0 GCP
HOH
 7.028
2.939
 CB
O
 O1B
O
CYS B:81 B:81 0.0 0.0 E -96.6 150.8 0.0 0.0 0.0 GCP
HOH
 7.033
7.440
 CB
N
 O1B
O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 CYS B:83 B:81 3.0 0.022 E -102.0 139.8 3.0 0.022 0.0 GOL
HOH
 8.029
6.497
 CB
CB
 O1
O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 CYS B:83 B:81 1.0 0.007 E -101.0 146.9 1.0 0.007 0.0 GDP
HOH
 6.674
8.006
 CB
CB
 O3B
O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 CYS B:83 B:81 1.0 0.007 E -101.4 148.9 1.0 0.007 0.0 GTP
HOH
 6.800
2.875
 CB
O
 O2B
O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 CYS A:85 A:81 0.0 0.0 E -108.8 151.6 0.0 0.0 0.0 MG
GNP
HOH
 9.846
6.668
2.666
 CB
CB
O
 MG
O2B
O
CYS B:85 B:81 0.0 0.0 E -105.5 153.3 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 CYS A:84 A:81 0.0 0.0 E -112.2 149.6 0.0 0.0 0.0 MG
GDP
 9.929
6.868
 CB
CB
 MG
O1B
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 CYS B:81 C:81 3.0 0.022 E -109.5 154.0 NA NA NA
CYS C:81 D:81 1.0 0.007 E -106.8 142.4 1.0 0.007 0.0 GOL
HOH
 7.101
7.695
 CB
O
 O3
O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 CYS B:81 C:81 3.0 0.022 E -108.5 167.7 NA NA NA
CYS C:81 D:81 1.0 0.007 E -109.1 144.0 1.0 0.007 0.0 GDP
HOH
 6.938
7.208
 CB
O
 O3B
O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 CYS B:88 B:81 5.0 0.037 E -124.6 127.1 5.0 0.037 0.0
CYS D:88 D:81 6.0 0.044 E -117.3 159.0 NA NA NA
CYS F:88 F:81 3.0 0.022 E -117.1 154.9 NA NA NA
CYS H:88 H:81 4.0 0.03 E -125.9 130.9 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 CYS B:88 B:81 5.0 0.037 E -119.3 135.8 5.0 0.037 0.0
CYS D:88 D:81 5.0 0.037 E -124.7 159.5 NA NA NA
CYS F:88 F:81 4.0 0.03 E -112.3 146.2 NA NA NA
CYS H:88 H:81 4.0 0.03 E -119.5 122.4 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 CYS A:81 A:81 1.0 0.007 E -96.6 150.6 1.0 0.007 0.0 SO4
HOH
 6.751
2.924
 CB
O
 O2
O
CYS C:81 C:81 0.0 0.0 E -96.6 150.6 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 CYS B:81 B:81 0.0 0.0 E -98.9 152.1 0.0 0.0 0.0 HOH
 2.752
 O
 O
CYS D:81 D:1081 0.0 0.0 E -90.9 155.1 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 CYS B:81 B:81 0.0 0.0 E -104.9 145.9 0.0 0.0 0.0 HOH
 2.588
 O
 O
CYS D:81 D:1081 0.0 0.0 E -103.1 151.2 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 CYS B:88 B:81 1.0 0.007 E -105.3 139.8 1.0 0.007 0.0 PO4
HOH
 6.715
2.766
 CB
O
 O2
O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 CYS A:91 A:81 0.0 0.0 E -108.3 149.7 0.0 0.0 0.0 GDP
HOH
 6.772
2.891
 CB
O
 O3B
O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 CYS A:81 A:81 0.0 0.0 -139.2 158.7 0.0 0.0 0.0 GNP
MG
HOH
 2.665
9.652
8.049
 HG
HB3
HB3
 N7
MG
H1
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 CYS A:83 A:81 0.0 0.0 E -105.2 146.0 0.0 0.0 0.0 GDP
 6.812
 CB
 O1B
CYS C:83 C:81 0.0 0.0 E -106.1 145.9 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 CYS B:83 A:80 0.0 0.0 E -102.1 143.2 0.0 0.0 0.0 GNP
HOH
 7.062
2.878
 CB
O
 O1B
O
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 CYS B:83 B:81 0.0 0.0 E -116.2 145.9 0.0 0.0 0.0 GNP
 7.029
 CB
 O1B
CYS D:83 D:81 0.0 0.0 E -116.5 144.6 0.0 0.0 0.0 GNP
MG
 6.887
9.866
 CB
SG
 O2B
MG
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 CYS A:83 A:81 0.0 0.0 E -96.9 145.2 0.0 0.0 0.0 SO4
HOH
 6.593
7.492
 CB
N
 O2
O
CYS C:83 C:81 1.0 0.007 E -95.3 156.6 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 CYS A:81 A:81 0.0 0.0 E -98.1 143.8 0.0 0.0 0.0 GNP
MG
HOH
 6.857
9.623
2.672
 CB
SG
O
 O1B
MG
O
CYS C:81 C:81 0.0 0.0 E -100.0 144.3 0.0 0.0 0.0 GNP
MG
HOH
 6.838
9.610
2.723
 CB
SG
O
 O1B
MG
O
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 CYS B:81 B:81 1.0 0.007 E -120.0 151.2 1.0 0.007 0.0
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 CYS A:85 A:81 0.0 0.0 E -97.7 156.8 0.0 0.0 0.0 HOH
 2.914
 O
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 CYS A:81 A:81 0.0 0.0 E -104.5 140.3 0.0 0.0 0.0 GNP
MG
HOH
 6.088
8.956
2.759
 HB2
HG
O
 O2B
MG
O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 CYS A:81 A:81 4.0 0.03 E -100.2 144.8 4.0 0.03 0.0 GDP
HOH
 6.661
3.041
 CB
O
 O1B
O
CYS C:81 C:81 7.0 0.052 E -100.2 144.9 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 CYS A:83 A:81 0.0 0.0 E -105.8 147.9 0.0 0.0 0.0 GTP
MG
HOH
 6.866
9.340
2.842
 CB
CB
O
 O1B
MG
O
CYS B:83 B:81 0.0 0.0 E -106.2 147.7 0.0 0.0 0.0 GTP
MG
HOH
 6.819
8.994
2.666
 CB
SG
O
 O1B
MG
O
CYS C:83 C:81 0.0 0.0 E -106.6 167.7 0.0 0.0 0.0 GTP
MG
 6.756
9.448
 CB
SG
 O2B
MG
CYS D:83 D:81 0.0 0.0 E -116.3 166.4 0.0 0.0 0.0 GTP
MG
HOH
 7.001
9.566
9.900
 CB
SG
C
 O2B
MG
O
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 CYS C:81 C:81 0.0 0.0 E -96.4 136.1 0.0 0.0 0.0 GNP
 6.579
 CB
 O2B
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 CYS B:81 D:581 0.0 0.0 E -107.3 138.7 0.0 0.0 0.0 GNP
HOH
 6.732
7.569
 CB
SG
 O1B
O
CYS D:81 E:581 0.0 0.0 E -107.9 140.9 NA NA NA
CYS F:81 F:581 0.0 0.0 E -107.6 139.6 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 CYS B:82 B:81 0.0 0.0 E -106.5 144.2 0.0 0.0 0.0 GDP
HOH
 7.112
9.386
 CB
CB
 O3B
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 CYS A:81 A:81 0.0 0.0 E -94.9 139.7