Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22413349 . C A CCDS221.1:NM_001039802.1:c.476gCa>gAa_NP_001034891.1:p.159A>E Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 ALA A:160 A:159 13.0 0.113 T -61.4 -35.2 13.0 0.113 0.0 GCP
HOH
 2.984
3.465
 N
CB
 O6
O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 ALA B:166 B:159 11.0 0.096 T -68.8 -21.3 11.0 0.096 0.0 GDP
HOH
 2.828
2.687
 N
N
 O6
O
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 ALA B:162 B:159 16.0 0.139 T -60.8 -33.8 16.0 0.139 0.0 SO4
GOL
HOH
 9.304
7.449
2.845
 CB
O
N
 O2
O1
O
ALA D:162 D:159 17.0 0.148 T -71.3 -30.8 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 ALA A:159 A:159 10.0 0.087 T -70.5 -29.3 10.0 0.087 0.0 GDP
HOH
 2.929
3.131
 N
CB
 O6
O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 ALA A:159 A:159 12.0 0.104 T -76.6 -17.7 12.0 0.104 0.0 GDP
HOH
 3.020
3.030
 N
N
 O6
O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 ALA C:159 C:159 12.0 0.104 T -69.1 -29.9 12.0 0.104 0.0 GDP
HOH
 2.616
2.940
 N
N
 O6
O
ALA D:159 D:159 13.0 0.113 T -69.0 -26.7 13.0 0.113 0.0 GDP
HOH
 2.818
3.040
 N
N
 O6
O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 ALA C:160 C:159 9.0 0.078 T -62.1 -27.8 9.0 0.078 0.0 GDP
 2.522
 N
 O6
ALA D:160 D:159 11.0 0.096 T -60.9 -27.7 11.0 0.096 0.0 GDP
HOH
 2.875
3.009
 N
N
 O6
O
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 ALA B:162 B:159 16.0 0.139 T -60.6 -27.3 16.0 0.139 0.0
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 ALA A:159 A:159 12.0 0.104 T -61.4 -20.9 12.0 0.104 0.0 GDP
HOH
 3.202
3.153
 N
CB
 O6
O
ALA B:159 B:159 12.0 0.104 T -53.3 -22.3 12.0 0.104 0.0 GDP
HOH
 2.615
3.274
 N
N
 O6
O
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 ALA A:159 A:159 12.0 0.104 T -66.5 -26.5 12.0 0.104 0.0 GDP
HOH
 2.887
3.065
 N
N
 O6
O
ALA B:159 B:359 10.0 0.087 T -66.8 -26.4 10.0 0.087 0.0 GNH
HOH
 2.822
8.409
 N
O
 O6
O
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 ALA A:159 A:159 12.0 0.104 T -73.7 -24.7 12.0 0.104 0.0 GCP
HOH
 2.658
2.977
 N
N
 O6
O
ALA B:159 B:159 13.0 0.113 T -57.5 -20.5 13.0 0.113 0.0 GCP
HOH
 3.022
2.705
 N
N
 O6
O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ALA B:161 B:159 15.0 0.13 T -56.7 -32.5 15.0 0.13 0.0 GOL
HOH
 8.295
3.090
 CB
N
 C3
O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ALA B:161 B:159 15.0 0.13 T -57.4 -39.1 15.0 0.13 0.0 GDP
HOH
 3.079
2.918
 N
N
 O6
O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ALA B:161 B:159 15.0 0.13 T -66.3 -30.0 15.0 0.13 0.0 GTP
HOH
 2.961
3.209
 N
N
 O6
O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 ALA A:163 A:159 11.0 0.096 T -71.6 -26.4 11.0 0.096 0.0 GNP
HOH
 2.868
3.032
 N
N
 O6
O
ALA B:163 B:159 11.0 0.096 T -63.9 -18.6 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 ALA A:162 A:159 12.0 0.104 T -75.2 -14.0 12.0 0.104 0.0 GDP
HOH
 3.077
9.844
 N
N
 O6
O
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ALA B:159 C:159 17.0 0.148 T -67.9 -24.2 NA NA NA
ALA C:159 D:159 15.0 0.13 T -68.3 -22.0 15.0 0.13 0.0 GOL
HOH
 8.701
2.935
 CB
N
 O1
O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ALA B:159 C:159 16.0 0.139 T -80.8 -20.7 NA NA NA
ALA C:159 D:159 15.0 0.13 T -68.0 -19.9 15.0 0.13 0.0 GDP
HOH
 2.784
3.190
 N
CB
 O6
O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ALA B:166 B:159 13.0 0.113 T -56.5 -35.9 13.0 0.113 0.0
ALA D:166 D:159 12.0 0.104 T -65.8 -21.1 NA NA NA
ALA F:166 F:159 14.0 0.122 T -49.9 -33.4 NA NA NA
ALA H:166 H:159 16.0 0.139 T -56.0 -34.8 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ALA B:166 B:159 16.0 0.139 S -61.2 -29.1 16.0 0.139 0.0
ALA D:166 D:159 12.0 0.104 T -70.6 -18.9 NA NA NA
ALA F:166 F:159 13.0 0.113 T -57.2 -29.3 NA NA NA
ALA H:166 H:159 13.0 0.113 T -68.9 -31.4 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 ALA A:159 A:159 14.0 0.122 T -67.4 -42.5 14.0 0.122 0.0 SO4
HOH
 9.260
2.745
 CB
N
 O3
O
ALA C:159 C:159 14.0 0.122 T -67.3 -42.5 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ALA B:159 B:159 14.0 0.122 T -71.9 -33.6 14.0 0.122 0.0 HOH
 2.880
 N
 O
ALA D:159 D:1159 15.0 0.13 T -72.5 -28.7 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ALA B:159 B:159 16.0 0.139 T -68.8 -29.2 16.0 0.139 0.0 HOH
 2.744
 N
 O
ALA D:159 D:1159 15.0 0.13 T -66.9 -32.4 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 ALA B:166 B:159 17.0 0.148 T -56.7 -30.9 17.0 0.148 0.0 PO4
HOH
 9.240
2.698
 CB
N
 O1
O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 ALA A:169 A:159 13.0 0.113 T -63.0 -36.8 13.0 0.113 0.0 GDP
HOH
 3.005
3.114
 N
N
 O6
O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 ALA A:159 A:159 16.0 0.139 S -52.2 -174.0 16.0 0.139 0.0 GNP
 1.921
 HB2
 H1'
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 ALA A:161 A:159 11.0 0.096 T -66.1 -20.4 11.0 0.096 0.0 GDP
 2.624
 N
 O6
ALA C:161 C:159 12.0 0.104 T -66.0 -20.4 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ALA B:161 A:158 12.0 0.104 T -64.9 -23.6 12.0 0.104 0.0 GNP
HOH
 2.949
2.829
 N
N
 O6
O
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ALA B:161 B:159 12.0 0.104 T -75.9 -31.6 12.0 0.104 0.0 GNP
 2.908
 N
 O6
ALA D:161 D:159 13.0 0.113 T -69.9 -31.2 13.0 0.113 0.0 GNP
 3.343
 N
 O6
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 ALA A:161 A:159 12.0 0.104 T -64.1 -33.7 12.0 0.104 0.0 SO4
HOH
 9.367
2.791
 CB
N
 O1
O
ALA C:161 C:159 15.0 0.13 T -68.7 -26.8 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 ALA A:159 A:159 12.0 0.104 T -79.2 -26.0 12.0 0.104 0.0 GNP
HOH
 2.708
3.406
 N
CB
 O6
O
ALA C:159 C:159 13.0 0.113 T -78.8 -26.0 13.0 0.113 0.0 GNP
HOH
 2.714
3.374
 N
CB
 O6
O
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 ALA B:159 B:159 14.0 0.122 T -59.8 -34.7 14.0 0.122 0.0
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 ALA A:163 A:159 22.0 0.191 T -60.2 -34.7 22.0 0.191 0.0 HOH
 2.849
 N
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 ALA A:159 A:159 12.0 0.104 T -65.1 -30.5 12.0 0.104 0.0 GNP
HOH
 2.387
2.349
 H
H
 O6
O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 ALA A:159 A:159 14.0 0.122 T -50.5 -38.3 14.0 0.122 0.0 GDP
HOH
 2.869
3.316
 N
CB
 O6
O
ALA C:159 C:159 16.0 0.139 T -51.3 -38.2 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 ALA A:161 A:159 11.0 0.096 T -71.4 -20.4 11.0 0.096 0.0 GTP
HOH
 3.061
3.047
 N
N
 O6
O
ALA B:161 B:159 11.0 0.096 T -70.1 -27.6 11.0 0.096 0.0 GTP
HOH
 2.977
2.793
 N
N
 O6
O
ALA C:161 C:159 13.0 0.113 T -75.9 -27.7 13.0 0.113 0.0 GTP
HOH
 2.687
7.765
 N
N
 O6
O
ALA D:161 D:159 12.0 0.104 T -73.7 -29.1 12.0 0.104 0.0 GTP
 3.271
 N
 O6
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 ALA C:159 C:159 13.0 0.113 T -66.7 -23.7 13.0 0.113 0.0 GNP
HOH
 2.608
9.017
 N
CB
 O6
O
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 ALA B:159 D:659 9.0 0.078 S -96.1 -39.6 9.0 0.078 0.0 GNP
HOH
 2.785
2.855
 N
CB
 O6
O
ALA D:159 E:659 9.0 0.078 S -94.3 -39.1 NA NA NA
ALA F:159 F:659 10.0 0.087 S -93.5 -38.7 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 ALA B:160 B:159 12.0 0.104 T -65.6 -32.3 12.0 0.104 0.0 GDP
HOH
 2.594
9.963
 N
N
 O6
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 ALA A:159 A:159 11.0 0.096 T -68.0 -28.0