Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22417943 . A C CCDS221.1:NM_001039802.1:c.509gAc>gCc_NP_001034891.1:p.170D>A Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 ASP A:171 A:170 46.0 0.307 H -64.0 -39.4 24.0 0.16 0.147 B:Q9NQU5:0.147
 SO4
HOH
 7.413
2.788
 OD2
OD1
 O4
O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 ASP B:177 B:170 47.0 0.313 H -62.7 -48.4 47.0 0.313 0.0 HOH
 5.453
 O
 O
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 ASP B:173 B:170 81.0 0.54 H -64.4 -42.8 81.0 0.54 0.0 GOL
HOH
 8.452
4.686
 OD2
OD2
 C1
O
ASP D:173 D:170 21.0 0.14 H -64.8 -43.4 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 ASP A:170 A:170 52.0 0.347 H -68.0 -46.5 52.0 0.347 0.0 HOH
 2.884
 OD1
 O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 ASP A:170 A:170 52.0 0.347 H -76.9 -35.2 52.0 0.347 0.0 HOH
 2.800
 OD1
 O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 ASP C:170 C:170 17.0 0.113 H -65.0 -47.2 17.0 0.113 0.0 HOH
 2.453
 OD1
 O
ASP D:170 D:170 19.0 0.127 H -62.6 -46.2 19.0 0.127 0.0 HOH
 2.779
 OD1
 O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 ASP C:171 C:170 54.0 0.36 H -60.8 -44.1 54.0 0.36 0.0
ASP D:171 D:170 37.0 0.247 H -61.3 -48.9 37.0 0.247 0.0
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 ASP B:173 B:170 54.0 0.36 H -56.9 -47.6 54.0 0.36 0.0
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 ASP A:170 A:170 52.0 0.347 H -74.6 -43.3 52.0 0.347 0.0 HOH
 6.284
 OD2
 O
ASP B:170 B:170 56.0 0.373 H -65.6 -48.4 56.0 0.373 0.0 HOH
 9.482
 OD2
 O
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 ASP A:170 A:170 74.0 0.493 H -69.1 -46.2 5.0 0.033 0.46 B:P60953:0.46
 HOH
 5.345
 O
 O
ASP B:170 B:370 74.0 0.493 H -69.6 -44.8 7.0 0.047 0.446 A:P60953:0.447
 HOH
 2.864
 OD2
 O
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 ASP A:170 A:170 54.0 0.36 H -65.5 -44.1 3.0 0.02 0.34 B:P60953:0.34
 SO4
HOH
 7.686
5.378
 OD2
O
 O4
O
ASP B:170 B:170 55.0 0.367 H -68.0 -43.2 7.0 0.047 0.32 A:P60953:0.32
 SO4
HOH
 7.434
3.139
 OD2
OD1
 O4
O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ASP B:172 B:170 20.0 0.133 H -57.1 -44.5 20.0 0.133 0.0 HOH
 2.704
 OD1
 O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ASP B:172 B:170 25.0 0.167 H -63.1 -65.3 25.0 0.167 0.0 HOH
 5.258
 OD1
 O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 ASP B:172 B:170 21.0 0.14 H -62.8 -50.9 21.0 0.14 0.0 HOH
 2.609
 OD2
 O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 ASP A:174 A:170 44.0 0.293 H -60.7 -42.8 24.0 0.16 0.133 C:Q9JK83:0.133
 HOH
 2.576
 OD1
 O
ASP B:174 B:170 50.0 0.333 H -59.3 -47.5 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 ASP A:173 A:170 49.0 0.327 H -66.1 -39.9 49.0 0.327 0.0 HOH
 2.577
 OD1
 O
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ASP B:170 C:170 22.0 0.147 H -56.9 -44.3 NA NA NA
ASP C:170 D:170 53.0 0.353 H -56.2 -36.9 53.0 0.353 0.0 HOH
 2.648
 O
 O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 ASP B:170 C:170 25.0 0.167 H -54.1 -45.7 NA NA NA
ASP C:170 D:170 55.0 0.367 H -58.9 -44.5 55.0 0.367 0.0 HOH
 2.698
 O
 O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ASP B:177 B:170 25.0 0.167 H -71.1 -42.3 25.0 0.167 0.0
ASP D:177 D:170 31.0 0.207 H -54.8 -38.0 NA NA NA
ASP F:177 F:170 15.0 0.1 H -67.1 -33.3 NA NA NA
ASP H:177 H:170 15.0 0.1 H -70.9 -40.5 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 ASP B:177 B:170 24.0 0.16 H -59.7 -45.3 24.0 0.16 0.0
ASP D:177 D:170 34.0 0.227 H -49.8 -44.5 NA NA NA
ASP F:177 F:170 23.0 0.153 H -60.0 -35.3 NA NA NA
ASP H:177 H:170 16.0 0.107 H -62.8 -39.3 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 ASP A:170 A:170 46.0 0.307 H -69.7 -45.1 46.0 0.307 0.0 HOH
 2.801
 OD1
 O
ASP C:170 C:170 47.0 0.313 H -69.5 -45.1 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ASP B:170 B:170 83.0 0.553 H -68.1 -46.3 83.0 0.553 0.0 HOH
 3.018
 OD1
 O
ASP D:170 D:1170 52.0 0.347 H -67.6 -47.5 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 ASP B:170 B:170 83.0 0.553 H -64.6 -43.6 83.0 0.553 0.0 HOH
 2.613
 OD1
 O
ASP D:170 D:1170 48.0 0.32 H -67.9 -44.5 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 ASP B:177 B:170 14.0 0.093 H -64.4 -42.0 14.0 0.093 0.0 HOH
 2.520
 OD1
 O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 ASP A:180 A:170 53.0 0.353 H -61.2 -48.4 10.0 0.067 0.286 B:O30916:0.287
 HOH
 2.927
 OD1
 O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 ASP A:170 A:170 83.0 0.553 H -63.3 -37.9 43.0 0.287 0.266 B:P35465:0.267
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 ASP A:172 A:170 53.0 0.353 H -70.9 -44.0 53.0 0.353 0.0
ASP C:172 C:170 56.0 0.373 H -70.3 -44.2 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ASP B:172 A:169 58.0 0.387 H -53.6 -51.0 58.0 0.387 0.0 HOH
 7.373
 CB
 O
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 ASP B:172 B:170 57.0 0.38 H -68.3 -44.9 57.0 0.38 0.0
ASP D:172 D:170 85.0 0.567 H -72.8 -40.3 85.0 0.567 0.0
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 ASP A:172 A:170 61.0 0.407 H -63.6 -45.7 61.0 0.407 0.0 HOH
 5.604
 O
 O
ASP C:172 C:170 56.0 0.373 H -61.4 -42.5 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 ASP A:170 A:170 61.0 0.407 H -65.7 -38.7 61.0 0.407 0.0
ASP C:170 C:170 60.0 0.4 H -66.4 -38.6 60.0 0.4 0.0
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 ASP B:170 B:170 54.0 0.36 H -65.4 -43.3 54.0 0.36 0.0
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 ASP A:174 A:170 24.0 0.16 H -67.1 -41.6 24.0 0.16 0.0 HOH
 2.790
 OD1
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 ASP A:170 A:170 52.0 0.347 H -59.9 -44.2 29.0 0.193 0.154 B:Q9UQB8:0.153
 HOH
 2.701
 OD2
 O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 ASP A:170 A:170 49.0 0.327 H -64.5 -44.9 49.0 0.327 0.0 HOH
 8.307
 N
 O
ASP C:170 C:170 23.0 0.153 H -65.3 -44.1 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 ASP A:172 A:170 40.0 0.267 H -60.7 -42.9 40.0 0.267 0.0 HOH
 8.959
 OD2
 O
ASP B:172 B:170 45.0 0.3 H -69.7 -42.3 45.0 0.3 0.0 HOH
 2.866
 OD1
 O
ASP C:172 C:170 59.0 0.393 H -68.6 -47.8 59.0 0.393 0.0
ASP D:172 D:170 57.0 0.38 H -71.4 -48.9 57.0 0.38 0.0
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 ASP C:170 C:170 61.0 0.407 H -56.7 -48.8 32.0 0.213 0.194 A:O96013:0.193
 HOH
 6.366
 OD2
 O
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 ASP B:170 D:670 68.0 0.453 H -52.7 -55.9 68.0 0.453 0.0 HOH
 2.634
 OD1
 O
ASP D:170 E:670 65.0 0.433 H -53.7 -55.0 NA NA NA
ASP F:170 F:670 68.0 0.453 H -53.0 -55.0 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 ASP B:171 B:170 62.0 0.413 H -54.1 -53.5 62.0 0.413 0.0 HOH
 8.131
 N
 O
6sup 1 Q8GF99,Q8GF97,P60953 84.21 1.0 X-RAY
 2019-12-04 ASP A:2119 A:2331 65.0 0.433 H -64.2 -30.2 65.0 0.433 0.0 HOH
 5.603
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 ASP A:170 A:170 53.0 0.353 H -58.7 -47.4