Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 22417945 . G A CCDS221.1:NM_001039802.1:c.511Gaa>Aaa_NP_001034891.1:p.171E>K Homo sapiens cell division cycle 42 (CDC42), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2odb 1 P60953 100.0 1e-141 X-RAY
 2007-01-30 GLU A:172 A:171 39.0 0.205 H -71.9 -28.3 39.0 0.205 0.0 HOH
 6.645
 CG
 O
5c2j 2 P60766 100.0 1e-141 X-RAY
 2016-06-22 GLU B:178 B:171 34.0 0.179 H -64.2 -34.4 34.0 0.179 0.0 HOH
 2.841
 O
 O
2dfk 2 P60953 100.0 1e-141 X-RAY
 2006-05-02 GLU B:174 B:171 36.0 0.189 H -65.3 -32.7 36.0 0.189 0.0 HOH
 6.259
 CG
 O
GLU D:174 D:171 39.0 0.205 H -70.2 -33.7 NA NA NA
1grn 1 P60953 100.0 2e-141 X-RAY
 1999-12-22 GLU A:171 A:171 30.0 0.158 H -61.7 -34.3 30.0 0.158 0.0 HOH
 5.090
 OE2
 O
2ngr 1 P60953 100.0 2e-141 X-RAY
 1999-01-06 GLU A:171 A:171 38.0 0.2 H -76.5 -27.3 38.0 0.2 0.0 HOH
 2.731
 O
 O
4itr 2 P60953 100.0 2e-141 X-RAY
 2013-02-20 GLU C:171 C:171 29.0 0.153 H -65.8 -36.1 29.0 0.153 0.0 HOH
 2.585
 O
 O
GLU D:171 D:171 39.0 0.205 H -67.2 -31.9 39.0 0.205 0.0 HOH
 2.432
 OE1
 O
6siu 2 P60953 100.0 3e-141 X-RAY
 2020-03-18 GLU C:172 C:171 35.0 0.184 H -69.2 -31.2 35.0 0.184 0.0 HOH
 9.974
 O
 O
GLU D:172 D:171 37.0 0.195 H -67.3 -32.5 37.0 0.195 0.0
5fi1 2 P60953 100.0 3e-141 X-RAY
 2016-04-20 GLU B:174 B:171 39.0 0.205 H -64.7 -33.5 39.0 0.205 0.0
1an0 1 P60953 100.0 1e-140 X-RAY
 1999-01-13 GLU A:171 A:171 37.0 0.195 H -60.4 -36.2 37.0 0.195 0.0 HOH
 3.695
 OE2
 O
GLU B:171 B:171 44.0 0.232 H -59.1 -42.4 44.0 0.232 0.0
1a4r 1 P60953 99.48 4e-140 X-RAY
 1999-03-02 GLU A:171 A:171 39.0 0.205 H -61.8 -43.4 19.0 0.1 0.105 B:P60953:0.105
 HOH
 2.535
 OE1
 O
GLU B:171 B:371 35.0 0.184 H -64.1 -40.2 14.0 0.074 0.11 A:P60953:0.111
 HOH
 7.971
 N
 O
2qrz 1 P60953 100.0 4e-140 X-RAY
 2008-03-18 GLU A:171 A:171 36.0 0.189 H -65.8 -35.8 12.0 0.063 0.126 B:P60953:0.126
 SO4
HOH
 9.590
2.633
 CG
OE1
 O4
O
GLU B:171 B:171 39.0 0.205 H -66.4 -41.0 9.0 0.047 0.158 A:P60953:0.158
 HOH
 2.745
 OE1
 O
2wm9 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 GLU B:173 B:171 34.0 0.179 H -69.9 -36.4 34.0 0.179 0.0 HOH
 6.288
 N
 O
2wmn 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 GLU B:173 B:171 38.0 0.2 H -51.5 -37.4 38.0 0.2 0.0 HOH
 8.057
 O
 O
2wmo 2 P60953 100.0 1e-139 X-RAY
 2009-09-22 GLU B:173 B:171 36.0 0.189 H -61.6 -36.1 36.0 0.189 0.0 HOH
 2.551
 OE1
 O
1nf3 1 P60953 98.95 1e-139 X-RAY
 2003-03-04 GLU A:175 A:171 39.0 0.205 H -67.2 -36.5 39.0 0.205 0.0 HOH
 2.718
 O
 O
GLU B:175 B:171 42.0 0.221 H -64.5 -38.6 NA NA NA
1doa 1 P60953 100.0 1e-139 X-RAY
 2000-02-09 GLU A:174 A:171 38.0 0.2 H -75.2 -29.4 38.0 0.2 0.0 HOH
 2.838
 OE1
 O
6tky 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 GLU B:171 C:171 32.0 0.168 H -70.4 -40.4 NA NA NA
GLU C:171 D:171 38.0 0.2 H -81.6 -36.8 38.0 0.2 0.0 HOH
 2.748
 OE2
 O
6tkz 2 P60953 100.0 2e-139 X-RAY
 2020-01-22 GLU B:171 C:171 32.0 0.168 H -68.1 -32.4 NA NA NA
GLU C:171 D:171 35.0 0.184 H -69.0 -36.2 35.0 0.184 0.0 HOH
 2.813
 O
 O
6aj4 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 GLU B:178 B:171 34.0 0.179 H -62.8 -42.4 34.0 0.179 0.0
GLU D:178 D:171 30.0 0.158 H -67.5 -56.8 NA NA NA
GLU F:178 F:171 34.0 0.179 H -70.3 -30.7 NA NA NA
GLU H:178 H:171 40.0 0.211 H -65.7 -40.2 NA NA NA
6ajl 2 P60953 100.0 1e-138 X-RAY
 2019-03-20 GLU B:178 B:171 35.0 0.184 H -67.7 -37.9 35.0 0.184 0.0
GLU D:178 D:171 28.0 0.147 H -67.6 -38.5 NA NA NA
GLU F:178 F:171 35.0 0.184 H -78.1 -33.5 NA NA NA
GLU H:178 H:171 32.0 0.168 H -66.8 -43.8 NA NA NA
1ki1 1 P60953 100.0 1e-138 X-RAY
 2002-05-29 GLU A:171 A:171 37.0 0.195 H -63.4 -39.5 37.0 0.195 0.0 HOH
 6.522
 N
 O
GLU C:171 C:171 37.0 0.195 H -63.4 -39.4 NA NA NA
1kz7 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 GLU B:171 B:171 28.0 0.147 H -61.6 -36.5 28.0 0.147 0.0 HOH
 2.624
 OE2
 O
GLU D:171 D:1171 31.0 0.163 H -62.3 -28.8 NA NA NA
1kzg 2 P60953 100.0 1e-138 X-RAY
 2002-03-20 GLU B:171 B:171 32.0 0.168 H -62.2 -35.5 32.0 0.168 0.0 HOH
 6.489
 N
 O
GLU D:171 D:1171 30.0 0.158 H -59.3 -34.9 NA NA NA
3vhl 2 P60953 99.47 6e-138 X-RAY
 2012-06-20 GLU B:178 B:171 38.0 0.2 H -73.2 -29.5 38.0 0.2 0.0 HOH
 2.746
 OE1
 O
4did 1 P60953 100.0 2e-135 X-RAY
 2012-02-29 GLU A:181 A:171 46.0 0.242 H -61.9 -41.3 30.0 0.158 0.084 B:O30916:0.084
 HOH
 2.916
 O
 O
1e0a 1 P60953 99.46 1e-134 NMR
 2000-04-18 GLU A:171 A:171 58.0 0.305 H -86.5 -25.6 58.0 0.305 0.0
5hzk 1 P60953 96.79 3e-134 X-RAY
 2016-12-21 GLU A:173 A:171 40.0 0.211 H -70.2 -26.1 40.0 0.211 0.0
GLU C:173 C:171 42.0 0.221 H -70.3 -27.0 NA NA NA
4yc7 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 GLU B:173 A:170 36.0 0.189 H -63.4 -36.8 36.0 0.189 0.0 HOH
 2.980
 OE2
 O
4ydh 2 P60953 99.44 1e-131 X-RAY
 2015-05-13 GLU B:173 B:171 61.0 0.321 H -64.0 -22.7 61.0 0.321 0.0
GLU D:173 D:171 51.0 NA H -70.0 -24.0 51.0 NA NA
1gzs 1 P25763 100.0 3e-131 X-RAY
 2002-09-12 GLU A:173 A:171 32.0 0.168 H -62.1 -38.8 32.0 0.168 0.0 HOH
 2.586
 OE2
 O
GLU C:173 C:171 39.0 0.205 H -69.8 -33.0 NA NA NA
3eg5 1 P60766 99.44 6e-131 X-RAY
 2008-10-14 GLU A:171 A:171 41.0 0.216 H -73.7 -28.7 41.0 0.216 0.0 HOH
 7.702
 CG
 O
GLU C:171 C:171 42.0 0.221 H -73.4 -28.6 42.0 0.221 0.0 HOH
 7.687
 CG
 O
5upl 2 P60953 100.0 1e-130 X-RAY
 2017-12-27 GLU B:171 B:171 43.0 0.226 H -73.9 -35.9 9.0 0.047 0.179 A:O96013:0.179
3gcg 1 P60953 100.0 6e-130 X-RAY
 2009-07-21 GLU A:175 A:171 35.0 0.184 H -68.2 -34.2 35.0 0.184 0.0 HOH
 4.708
 OE1
 O
4js0 1 P60953 99.44 6e-130 X-RAY
 2014-03-05 GLU A:171 A:171 54.0 0.284 H -72.9 -32.3 54.0 0.284 0.0 HOH
 2.525
 OE1
 O
3qbv 1 P60953 99.44 6e-130 X-RAY
 2012-02-08 GLU A:171 A:171 39.0 0.205 H -65.9 -32.0 39.0 0.205 0.0 HOH
 6.336
 CG
 O
GLU C:171 C:171 40.0 0.211 H -66.1 -31.2 NA NA NA
5cjp 1 A0A024RAE4 99.44 3e-129 X-RAY
 2016-08-10 GLU A:173 A:171 33.0 0.174 H -70.4 -37.4 33.0 0.174 0.0 HOH
 9.541
 O
 O
GLU B:173 B:171 32.0 0.168 H -66.6 -49.8 32.0 0.168 0.0 HOH
 8.301
 N
 O
GLU C:173 C:171 38.0 0.2 H -65.2 -30.5 38.0 0.2 0.0
GLU D:173 D:171 39.0 0.205 H -63.2 -35.2 39.0 0.205 0.0
5upk 3 P60953 98.87 4e-129 X-RAY
 2017-12-27 GLU C:171 C:171 48.0 0.253 H -71.2 -39.5 10.0 0.053 0.2 B:O96013:0.2
 HOH
 4.734
 OE2
 O
1am4 2 P60953 99.43 7e-129 X-RAY
 1998-07-15 GLU B:171 D:671 42.0 0.221 H -69.7 -7.6 42.0 0.221 0.0 HOH
 6.045
 CG
 O
GLU D:171 E:671 41.0 0.216 H -71.0 -6.6 NA NA NA
GLU F:171 F:671 43.0 0.226 H -70.2 -8.1 NA NA NA
7s0y 2 P60953 99.43 8e-129 X-RAY
 2021-09-08 GLU B:172 B:171 36.0 0.189 H -67.5 -22.2 36.0 0.189 0.0 HOH
 6.459
 CG
 O
6sup 1 Q8GF99,Q8GF97,P60953 84.21 1.0 X-RAY
 2019-12-04 GLU A:2120 A:2332 106.0 0.558 H -64.3 -40.3 106.0 0.558 0.0 HOH
 2.834
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60953-f1 1 P60953 100.0 8e-142 GLU A:171 A:171 33.0 0.174 H -68.3 -32.1