Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 23376891 | . | G | A | CCDS30627.1:NM_015013.3:c.529Gca>Aca_NP_055828.2:p.177A>T | Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3zmu | 1 | O60341 | 99.54 | 0.0 |
X-RAY |
2013-06-12 | ALA | A:197 | A:177 | 6.0 | 0.052 | H | -64.1 | -39.9 | 6.0 | 0.052 | 0.0 | ||||||
| 3zmv | 1 | O60341 | 99.54 | 0.0 |
X-RAY |
2013-06-12 | ALA | A:197 | A:177 | 6.0 | 0.052 | H | -57.6 | -46.6 | 6.0 | 0.052 | 0.0 | ||||||
| 3zms | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | ALA | A:197 | A:177 | 6.0 | 0.052 | H | -66.8 | -41.2 | 6.0 | 0.052 | 0.0 | ||||||
| 3zmt | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | ALA | A:197 | A:177 | 6.0 | 0.052 | H | -62.9 | -38.4 | 6.0 | 0.052 | 0.0 | ||||||
| 3zmz | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | ALA | A:197 | A:177 | 6.0 | 0.052 | H | -64.2 | -35.5 | 6.0 | 0.052 | 0.0 | ||||||
| 3zn0 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | ALA | A:197 | A:177 | 6.0 | 0.052 | H | -66.6 | -41.5 | 6.0 | 0.052 | 0.0 | ||||||
| 3zn1 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | ALA | A:197 | A:177 | 7.0 | 0.061 | H | -61.8 | -41.6 | 7.0 | 0.061 | 0.0 | ||||||
| 4czz | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-06-11 | ALA | A:197 | A:177 | 5.0 | 0.043 | H | -59.4 | -38.9 | 5.0 | 0.043 | 0.0 | ||||||
| 4uv8 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | ALA | A:197 | A:177 | 6.0 | 0.052 | H | -60.2 | -37.1 | 6.0 | 0.052 | 0.0 | ||||||
| 4uv9 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | ALA | A:197 | A:177 | 6.0 | 0.052 | H | -58.7 | -41.3 | 6.0 | 0.052 | 0.0 | ||||||
| 4uva | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | ALA | A:197 | A:177 | 6.0 | 0.052 | H | -63.6 | -35.6 | 6.0 | 0.052 | 0.0 | ||||||
| 4uvb | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | ALA | A:197 | A:177 | 5.0 | 0.043 | H | -64.2 | -37.6 | 5.0 | 0.043 | 0.0 | ||||||
| 4uvc | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | ALA | A:197 | A:177 | 7.0 | 0.061 | H | -56.1 | -42.6 | 7.0 | 0.061 | 0.0 | ||||||
| 6tuy | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2021-07-21 | ALA | A:177 | A:177 | 8.0 | 0.07 | H | -41.9 | -44.5 | 8.0 | 0.07 | 0.0 |
HOH |
9.703 |
C |
O |
||
| 2xaf | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | ALA | A:177 | A:177 | 5.0 | 0.043 | H | -42.6 | -58.4 | 5.0 | 0.043 | 0.0 | ||||||
| 2xag | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | ALA | A:177 | A:177 | 5.0 | 0.043 | H | -55.7 | -52.7 | 5.0 | 0.043 | 0.0 | ||||||
| 2xah | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | ALA | A:177 | A:177 | 9.0 | 0.078 | H | -45.4 | -43.4 | 9.0 | 0.078 | 0.0 | ||||||
| 2xaj | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | ALA | A:177 | A:177 | 8.0 | 0.07 | H | -47.8 | -45.5 | 8.0 | 0.07 | 0.0 | ||||||
| 2xaq | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | ALA | A:177 | A:177 | 6.0 | 0.052 | H | -68.8 | -24.1 | 6.0 | 0.052 | 0.0 | ||||||
| 2xas | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | ALA | A:177 | A:177 | 7.0 | 0.061 | H | -44.8 | -49.8 | 7.0 | 0.061 | 0.0 | ||||||
| 4uxn | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2015-02-25 | ALA | A:177 | A:177 | 7.0 | 0.061 | H | -56.5 | -42.4 | 7.0 | 0.061 | 0.0 | ||||||
| 5lhg | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | ALA | A:177 | A:177 | 8.0 | 0.07 | H | -65.4 | -30.8 | 8.0 | 0.07 | 0.0 | ||||||
| 5lhh | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | ALA | A:177 | A:177 | 5.0 | 0.043 | H | -58.3 | -44.1 | 5.0 | 0.043 | 0.0 |
HOH |
8.100 |
O |
O |
||
| 5lhi | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | ALA | A:177 | A:177 | 6.0 | 0.052 | H | -64.9 | -43.0 | 6.0 | 0.052 | 0.0 |
HOH |
8.913 |
O |
O |
||
| 6te1 | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2020-06-03 | ALA | A:177 | A:177 | 6.0 | 0.052 | H | -61.8 | -33.9 | 6.0 | 0.052 | 0.0 | ||||||
| 5l3c | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | ALA | A:177 | A:177 | 6.0 | 0.052 | H | -69.2 | -35.6 | 6.0 | 0.052 | 0.0 | ||||||
| 5l3d | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | ALA | A:177 | A:177 | 5.0 | 0.043 | H | -64.3 | -39.5 | 5.0 | 0.043 | 0.0 |
HOH |
7.205 |
N |
O |
||
| 5l3b | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | ALA | A:177 | A:177 | 7.0 | 0.061 | H | -61.2 | -42.0 | 7.0 | 0.061 | 0.0 | ||||||
| 2x0l | 1 | O60341 | 100.0 | 0.0 |
X-RAY |
2010-03-02 | ALA | A:55 | A:177 | 7.0 | 0.061 | H | -44.7 | -53.3 | 7.0 | 0.061 | 0.0 | ||||||
| 4bay | 1 | O60341 | 99.85 | 0.0 |
X-RAY |
2013-11-27 | ALA | A:7 | A:177 | 5.0 | 0.043 | H | -64.2 | -41.2 | 5.0 | 0.043 | 0.0 | ||||||
| 2v1d | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2007-05-29 | ALA | A:55 | A:177 | 6.0 | 0.052 | H | -53.0 | -47.3 | 6.0 | 0.052 | 0.0 | ||||||
| 2y48 | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2011-02-16 | ALA | A:55 | A:177 | 7.0 | 0.061 | H | -50.7 | -51.7 | 7.0 | 0.061 | 0.0 | ||||||
| 5l3e | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | ALA | A:55 | A:177 | 8.0 | 0.07 | H | -49.5 | -39.9 | 8.0 | 0.07 | 0.0 | ||||||
| 5l3f | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | ALA | A:55 | A:177 | 7.0 | 0.061 | H | -57.5 | -48.5 | 7.0 | 0.061 | 0.0 | ||||||
| 5l3g | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | ALA | A:55 | A:177 | 7.0 | 0.061 | H | -52.1 | -46.1 | 7.0 | 0.061 | 0.0 | ||||||
| 5lbq | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | ALA | A:55 | A:177 | 6.0 | 0.052 | H | -57.5 | -51.1 | 6.0 | 0.052 | 0.0 | ||||||
| 5lgt | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2017-02-22 | ALA | A:55 | A:177 | 6.0 | 0.052 | H | -61.2 | -44.7 | 6.0 | 0.052 | 0.0 | ||||||
| 5lgu | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2017-02-22 | ALA | A:55 | A:177 | 5.0 | 0.043 | H | -65.1 | -40.7 | 5.0 | 0.043 | 0.0 | ||||||
| 6vyp | 7 | O60341 | 98.69 | 0.0 |
X-RAY |
2020-05-27 | ALA | S:9 | M:177 | 4.0 | 0.035 | H | -66.7 | -41.7 | 4.0 | 0.035 | 0.0 | ||||||
| ALA | U:9 | m:177 | 5.0 | 0.043 | H | -65.8 | -40.7 | NA | NA | NA | |||||||||||||
| ALA | W:9 | K:177 | 3.0 | 0.026 | H | -72.6 | -33.5 | 3.0 | 0.026 | 0.0 | |||||||||||||
| ALA | Y:9 | k:177 | 0.0 | 0.0 | T | -153.6 | -63.8 | NA | NA | NA | |||||||||||||
| 5lgn | 1 | O60341 | 99.85 | 0.0 |
X-RAY |
2017-02-22 | ALA | A:7 | A:177 | 6.0 | 0.052 | H | -63.8 | -47.2 | 6.0 | 0.052 | 0.0 | ||||||
| 2iw5 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2006-08-09 | ALA | A:7 | A:177 | 5.0 | 0.043 | H | -62.3 | -41.5 | 5.0 | 0.043 | 0.0 |
HOH |
7.616 |
O |
O |
||
| 2uxn | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-05-29 | ALA | A:7 | A:177 | 4.0 | 0.035 | H | -64.4 | -40.1 | 4.0 | 0.035 | 0.0 |
HOH |
7.541 |
O |
O |
||
| 2uxx | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-08-21 | ALA | A:7 | A:177 | 3.0 | 0.026 | H | -64.3 | -37.8 | 3.0 | 0.026 | 0.0 | ||||||
| 4kum | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2014-05-07 | ALA | A:7 | A:177 | 5.0 | 0.043 | H | -62.4 | -41.7 | 5.0 | 0.043 | 0.0 | ||||||
| 4xbf | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2016-04-27 | ALA | A:7 | A:177 | 7.0 | 0.061 | H | -61.8 | -35.6 | 7.0 | 0.061 | 0.0 | ||||||
| 6wc6 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-30 | ALA | A:7 | A:177 | 6.0 | 0.052 | H | -64.8 | -37.8 | 6.0 | 0.052 | 0.0 | ||||||
| 2h94 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2006-07-04 | ALA | A:6 | A:177 | 7.0 | 0.061 | H | -50.1 | -40.2 | 7.0 | 0.061 | 0.0 | ||||||
| 2hko | 1 | O60341 | 99.25 | 0.0 |
X-RAY |
2006-08-29 | ALA | A:6 | A:177 | 6.0 | 0.052 | H | -69.9 | -56.2 | 6.0 | 0.052 | 0.0 |
HOH |
7.347 |
C |
O |
||
| 7e0g | 1 | O60341 | 99.1 | 0.0 |
X-RAY |
2021-03-24 | ALA | A:9 | A:177 | 6.0 | 0.052 | H | -57.0 | -45.7 | 6.0 | 0.052 | 0.0 |
HOH |
5.319 |
O |
O |
||
| 6s35 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-02-26 | ALA | A:10 | A:177 | 7.0 | 0.061 | H | -64.0 | -36.8 | 7.0 | 0.061 | 0.0 | ||||||
| 5h6q | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | ALA | A:13 | A:177 | 4.0 | 0.035 | H | -71.5 | -45.3 | 4.0 | 0.035 | 0.0 |
HOH |
6.210 |
N |
O |
||
| 5h6r | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | ALA | A:13 | A:177 | 4.0 | 0.035 | H | -69.7 | -39.8 | 4.0 | 0.035 | 0.0 |
HOH |
7.706 |
O |
O |
||
| 5x60 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | ALA | A:13 | A:177 | 5.0 | 0.043 | H | -66.6 | -40.3 | 5.0 | 0.043 | 0.0 |
HOH |
7.652 |
O |
O |
||
| 5yjb | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2018-07-04 | ALA | A:13 | A:177 | 5.0 | 0.043 | H | -53.7 | -40.2 | 5.0 | 0.043 | 0.0 | ||||||
| 6kgk | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | ALA | A:13 | A:177 | 5.0 | 0.043 | H | -57.7 | -45.7 | 5.0 | 0.043 | 0.0 |
HOH |
5.390 |
O |
O |
||
| 6kgl | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | ALA | A:13 | A:177 | 5.0 | 0.043 | H | -57.0 | -46.0 | 5.0 | 0.043 | 0.0 |
HOH |
5.347 |
O |
O |
||
| 6kgm | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | ALA | A:13 | A:177 | 5.0 | 0.043 | H | -56.3 | -44.3 | 5.0 | 0.043 | 0.0 |
HOH |
7.738 |
O |
O |
||
| 6kgn | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | ALA | A:13 | A:177 | 5.0 | 0.043 | H | -56.0 | -44.1 | 5.0 | 0.043 | 0.0 |
HOH |
7.746 |
O |
O |
||
| 6kgo | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | ALA | A:13 | A:177 | 6.0 | 0.052 | H | -66.3 | -38.5 | 6.0 | 0.052 | 0.0 |
HOH |
5.460 |
O |
O |
||
| 6kgp | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | ALA | A:13 | A:177 | 6.0 | 0.052 | H | -66.5 | -38.2 | 6.0 | 0.052 | 0.0 |
HOH |
5.455 |
O |
O |
||
| 6kgq | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | ALA | A:13 | A:177 | 4.0 | 0.035 | H | -70.2 | -43.3 | 4.0 | 0.035 | 0.0 |
HOH |
5.566 |
O |
O |
||
| 6kgr | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | ALA | A:13 | A:177 | 4.0 | 0.035 | H | -70.0 | -43.3 | 4.0 | 0.035 | 0.0 |
HOH |
5.563 |
O |
O |
||
| 7cdc | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | ALA | A:13 | A:177 | 4.0 | 0.035 | H | -71.3 | -43.9 | 4.0 | 0.035 | 0.0 |
HOH |
6.086 |
N |
O |
||
| 7cdd | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | ALA | A:13 | A:177 | 5.0 | 0.043 | H | -74.0 | -39.7 | 5.0 | 0.043 | 0.0 |
HOH |
6.081 |
N |
O |
||
| 7cde | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | ALA | A:13 | A:177 | 4.0 | 0.035 | H | -69.9 | -43.9 | 4.0 | 0.035 | 0.0 |
GOL HOH |
9.974 5.967 |
O N |
O3 O |
||
| 7cdf | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | ALA | A:13 | A:177 | 5.0 | 0.043 | H | -69.7 | -44.2 | 5.0 | 0.043 | 0.0 |
HOH |
7.521 |
O |
O |
||
| 7cdg | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | ALA | A:13 | A:177 | 5.0 | 0.043 | H | -67.4 | -40.3 | 5.0 | 0.043 | 0.0 |
HOH |
6.049 |
N |
O |
||
| 2ejr | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-01-01 | ALA | A:6 | A:177 | 6.0 | 0.052 | H | -60.7 | -47.4 | 6.0 | 0.052 | 0.0 |
HOH |
5.692 |
O |
O |
||
| 2z3y | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-01-01 | ALA | A:6 | A:177 | 7.0 | 0.061 | H | -62.1 | -40.3 | 7.0 | 0.061 | 0.0 |
HOH |
5.415 |
O |
O |
||
| 2z5u | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-04-01 | ALA | A:6 | A:177 | 6.0 | 0.052 | H | -64.2 | -40.2 | 6.0 | 0.052 | 0.0 |
HOH |
5.476 |
O |
O |
||
| 3abt | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2010-07-07 | ALA | A:6 | A:177 | 8.0 | 0.07 | H | -57.5 | -45.0 | 8.0 | 0.07 | 0.0 | ||||||
| 3abu | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2010-07-07 | ALA | A:6 | A:177 | 9.0 | 0.078 | H | -48.5 | -44.1 | 9.0 | 0.078 | 0.0 | ||||||
| 6k3e | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-05-20 | ALA | A:6 | A:177 | 8.0 | 0.07 | H | -71.8 | -36.6 | 8.0 | 0.07 | 0.0 |
GOL EDO EDO |
9.593 6.071 8.318 |
O N O |
O3 C1 O2 |
||
| 2dw4 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-09-04 | ALA | A:6 | A:177 | 4.0 | 0.035 | H | -63.4 | -41.9 | 4.0 | 0.035 | 0.0 |
HOH |
5.435 |
O |
O |
||
| 6w4k | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-10-21 | ALA | A:4 | A:177 | 9.0 | 0.078 | H | -99.0 | -27.7 | 9.0 | 0.078 | 0.0 | ||||||
| 6nqm | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-02-13 | ALA | A:5 | A:177 | 8.0 | 0.07 | H | -63.0 | -40.6 | 8.0 | 0.07 | 0.0 | ||||||
| 6nqu | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-02-13 | ALA | A:5 | A:177 | 7.0 | 0.061 | H | -58.9 | -47.6 | 7.0 | 0.061 | 0.0 | ||||||
| 6nr5 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-07-17 | ALA | A:5 | A:177 | 8.0 | 0.07 | H | -64.4 | -37.2 | 8.0 | 0.07 | 0.0 | ||||||
| 2l3d | 1 | O60341 | 99.01 | 2e-65 |
NMR |
2011-09-21 | ALA | A:6 | A:6 | 83.0 | 0.722 | -139.3 | 133.5 | 83.0 | 0.722 | 0.0 | |||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o60341-f1 | 1 | O60341 | 94.98 | 0.0 | ALA | A:177 | A:177 | 5.0 | 0.043 | H | -64.5 | -33.3 | |