Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23383989 . G A CCDS30627.1:NM_015013.3:c.943Gga>Aga_NP_055828.2:p.315G>R Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
2013-06-12 GLY A:335 A:315 8.0 0.107 T 59.9 -112.8 8.0 0.107 0.0 FAD
3.175
CA
O3B
3zmv 1 O60341 99.54 0.0 X-RAY
2013-06-12 GLY A:335 A:315 9.0 0.12 T 59.3 -115.8 9.0 0.12 0.0 FAD
3.093
CA
O3B
3zms 1 O60341 99.43 0.0 X-RAY
2013-06-12 GLY A:335 A:315 8.0 0.107 T 57.7 -107.9 8.0 0.107 0.0 FAD
3.220
CA
O3B
3zmt 1 O60341 99.43 0.0 X-RAY
2013-06-12 GLY A:335 A:315 8.0 0.107 T 56.0 -110.3 8.0 0.107 0.0 FAD
3.275
CA
O3B
3zmz 1 O60341 99.43 0.0 X-RAY
2013-06-12 GLY A:335 A:315 8.0 0.107 T 58.6 -115.1 8.0 0.107 0.0 FAD
3.249
CA
O3B
3zn0 1 O60341 99.43 0.0 X-RAY
2013-06-12 GLY A:335 A:315 10.0 0.133 T 62.8 -113.6 10.0 0.133 0.0 FAD
3.184
CA
O3B
3zn1 1 O60341 99.43 0.0 X-RAY
2013-06-12 GLY A:335 A:315 8.0 0.107 T 55.8 -112.9 8.0 0.107 0.0 FAD
3.216
CA
O3B
4czz 1 O60341 99.43 0.0 X-RAY
2014-06-11 GLY A:335 A:315 8.0 0.107 S 61.5 -127.8 8.0 0.107 0.0 FAD
3.309
CA
O3B
4uv8 1 O60341 99.43 0.0 X-RAY
2014-09-10 GLY A:335 A:315 9.0 0.12 T 61.5 -116.1 9.0 0.12 0.0 D69
HOH
3.224
6.668
CA
O
O3B
O
4uv9 1 O60341 99.43 0.0 X-RAY
2014-09-10 GLY A:335 A:315 9.0 0.12 T 53.0 -113.6 9.0 0.12 0.0 D70
3.178
CA
O3B
4uva 1 O60341 99.43 0.0 X-RAY
2014-09-10 GLY A:335 A:315 9.0 0.12 T 60.4 -114.8 9.0 0.12 0.0 D73
3.166
CA
O3B
4uvb 1 O60341 99.43 0.0 X-RAY
2014-09-10 GLY A:335 A:315 9.0 0.12 T 62.5 -115.4 9.0 0.12 0.0 D51
3.166
CA
O3B
4uvc 1 O60341 99.43 0.0 X-RAY
2014-09-10 GLY A:335 A:315 9.0 0.12 T 55.5 -123.1 9.0 0.12 0.0 D52
3.170
CA
O3B
6tuy 1 O60341 94.98 0.0 X-RAY
2021-07-21 GLY A:315 A:315 9.0 0.12 T 68.5 -135.5 9.0 0.12 0.0 FAD
CL
CL
GOL
DMS
HOH
3.232
7.317
6.786
8.764
6.674
4.462
CA
O
O
O
O
CA
O3B
CL
CL
O3
C1
O
2xaf 1 O60341 94.98 0.0 X-RAY
2010-05-05 GLY A:315 A:315 10.0 0.133 T 50.4 -126.9 10.0 0.133 0.0 FAD
3.259
CA
O3B
2xag 1 O60341 94.98 0.0 X-RAY
2010-05-05 GLY A:315 A:315 9.0 0.12 T 53.0 -110.5 9.0 0.12 0.0 FAD
3.166
CA
O3B
2xah 1 O60341 94.98 0.0 X-RAY
2010-05-05 GLY A:315 A:315 11.0 0.147 T 53.5 -116.1 11.0 0.147 0.0 FAD
3.495
CA
O2A
2xaj 1 O60341 94.98 0.0 X-RAY
2010-05-05 GLY A:315 A:315 8.0 0.107 T 51.2 -124.9 8.0 0.107 0.0 FAD
3.308
CA
O3B
2xaq 1 O60341 94.98 0.0 X-RAY
2010-05-05 GLY A:315 A:315 12.0 0.16 T 44.5 -118.6 12.0 0.16 0.0 FAD
3.645
CA
C3B
2xas 1 O60341 94.98 0.0 X-RAY
2010-05-05 GLY A:315 A:315 9.0 0.12 T 57.7 -116.6 9.0 0.12 0.0 FAD
3.368
CA
O3B
4uxn 1 O60341 94.98 0.0 X-RAY
2015-02-25 GLY A:315 A:315 8.0 0.107 T 59.6 -127.1 8.0 0.107 0.0 FAD
3.481
CA
O3B
5lhg 1 O60341 94.98 0.0 X-RAY
2017-02-22 GLY A:315 A:315 10.0 0.133 T 69.6 -117.7 10.0 0.133 0.0 FAD
GOL
HOH
3.167
5.891
2.951
CA
O
N
O3B
C3
O
5lhh 1 O60341 94.98 0.0 X-RAY
2017-02-22 GLY A:315 A:315 11.0 0.147 T 60.4 -123.4 11.0 0.147 0.0 FAD
GOL
GOL
HOH
3.186
5.796
6.665
2.802
CA
O
O
N
O3B
O3
C3
O
5lhi 1 O60341 94.98 0.0 X-RAY
2017-02-22 GLY A:315 A:315 7.0 0.093 T 59.3 -120.0 7.0 0.093 0.0 FAD
GOL
HOH
3.165
5.643
4.367
CA
O
CA
O3B
O3
O
6te1 1 O60341 94.98 0.0 X-RAY
2020-06-03 GLY A:315 A:315 11.0 0.147 T 61.1 -124.6 11.0 0.147 0.0 FAD
GOL
GOL
HOH
3.390
5.917
6.234
2.592
CA
O
O
N
O3B
O3
O3
O
5l3c 1 O60341 94.86 0.0 X-RAY
2016-05-04 GLY A:315 A:315 8.0 0.107 T 59.9 -115.3 8.0 0.107 0.0 FAD
3.326
CA
O3B
5l3d 1 O60341 94.86 0.0 X-RAY
2016-05-04 GLY A:315 A:315 10.0 0.133 T 63.1 -113.6 10.0 0.133 0.0 FAD
HOH
3.321
7.759
CA
O
O3B
O
5l3b 1 O60341 94.86 0.0 X-RAY
2016-05-04 GLY A:315 A:315 7.0 0.093 T 59.7 -115.1 7.0 0.093 0.0 FAD
3.272
CA
O3B
2x0l 1 O60341 100.0 0.0 X-RAY
2010-03-02 GLY A:193 A:315 8.0 0.107 T 54.9 -116.6 8.0 0.107 0.0 FAD
3.369
CA
O3B
4bay 1 O60341 99.85 0.0 X-RAY
2013-11-27 GLY A:145 A:315 7.0 0.093 T 54.5 -109.8 7.0 0.093 0.0 FAD
3.154
CA
O3B
2v1d 1 O60341 99.42 0.0 X-RAY
2007-05-29 GLY A:193 A:315 7.0 0.093 T 53.6 -129.8 7.0 0.093 0.0 FAD
3.342
CA
O3B
2y48 1 O60341 99.42 0.0 X-RAY
2011-02-16 GLY A:193 A:315 9.0 0.12 T 47.2 -107.0 9.0 0.12 0.0 FAD
3.395
CA
O3B
5l3e 1 O60341 99.42 0.0 X-RAY
2016-09-21 GLY A:193 A:315 10.0 0.133 T 62.7 -123.8 10.0 0.133 0.0 FAD
NA
3.217
6.560
CA
CA
O3B
NA
5l3f 1 O60341 99.42 0.0 X-RAY
2016-09-21 GLY A:193 A:315 9.0 0.12 S 56.9 -131.3 9.0 0.12 0.0 FAD
3.199
CA
O3B
5l3g 1 O60341 99.42 0.0 X-RAY
2016-09-21 GLY A:193 A:315 11.0 0.147 T 58.6 -122.0 11.0 0.147 0.0 FAD
NA
3.164
7.063
CA
CA
O3B
NA
5lbq 1 O60341 99.42 0.0 X-RAY
2016-09-21 GLY A:193 A:315 10.0 0.133 T 62.3 -122.6 10.0 0.133 0.0 FAD
3.485
CA
O3B
5lgt 1 O60341 99.42 0.0 X-RAY
2017-02-22 GLY A:193 A:315 8.0 0.107 T 60.1 -111.7 8.0 0.107 0.0 FAD
3.241
CA
O3B
5lgu 1 O60341 99.42 0.0 X-RAY
2017-02-22 GLY A:193 A:315 8.0 0.107 T 65.8 -120.2 8.0 0.107 0.0 FAD
3.194
CA
O3B
6vyp 7 O60341 98.69 0.0 X-RAY
2020-05-27 GLY S:147 M:315 10.0 0.133 S 65.3 -103.9 10.0 0.133 0.0 FAD
3.228
CA
O3B
GLY U:147 m:315 9.0 0.12 S 65.1 -103.2 NA NA NA
GLY W:147 K:315 12.0 0.16 S 62.6 -101.7 12.0 0.16 0.0 FAD
1.374
CA
O3B
GLY Y:147 k:315 9.0 0.12 S 66.2 -101.0 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
2017-02-22 GLY A:145 A:315 7.0 0.093 S 58.6 -115.8 7.0 0.093 0.0 FAD
3.201
CA
O3B
2iw5 1 O60341 99.4 0.0 X-RAY
2006-08-09 GLY A:145 A:315 11.0 0.147 T 55.6 -117.0 11.0 0.147 0.0 FAD
CL
CL
HOH
3.223
6.317
8.073
4.626
CA
O
O
CA
O3B
CL
CL
O
2uxn 1 O60341 99.4 0.0 X-RAY
2007-05-29 GLY A:145 A:315 11.0 0.147 T 49.2 -106.0 11.0 0.147 0.0 FDA
CL
HOH
3.145
7.124
4.578
CA
O
CA
O3B
CL
O
2uxx 1 O60341 99.4 0.0 X-RAY
2007-08-21 GLY A:145 A:315 11.0 0.147 T 49.2 -100.7 11.0 0.147 0.0 FAJ
HOH
3.216
4.666
CA
N
O15
O
4kum 1 O60341 99.4 0.0 X-RAY
2014-05-07 GLY A:145 A:315 8.0 0.107 T 54.3 -115.1 8.0 0.107 0.0 FAD
CL
HOH
3.238
6.859
4.517
CA
O
CA
O3B
CL
O
4xbf 1 O60341 99.4 0.0 X-RAY
2016-04-27 GLY A:145 A:315 11.0 0.147 T 64.5 -114.8 11.0 0.147 0.0 FAD
SO4
SO4
HOH
2.436
6.192
6.331
3.829
HA2
O
O
HA2
HO3A
O1
O3
O
6wc6 1 O60341 99.4 0.0 X-RAY
2021-06-30 GLY A:145 A:315 9.0 0.12 T 63.2 -118.9 9.0 0.12 0.0 FAD
3.104
CA
O3B
2h94 1 O60341 99.4 0.0 X-RAY
2006-07-04 GLY A:144 A:315 8.0 0.107 T 39.1 -113.3 8.0 0.107 0.0 FAD
HOH
2.787
2.724
CA
N
O3B
O
2hko 1 O60341 99.25 0.0 X-RAY
2006-08-29 GLY A:144 A:315 10.0 0.133 S 73.7 -106.6 10.0 0.133 0.0 FAD
HOH
3.339
2.917
CA
N
O3B
O
7e0g 1 O60341 99.1 0.0 X-RAY
2021-03-24 GLY A:147 A:315 11.0 0.147 T 55.7 -109.8 11.0 0.147 0.0 HUF
HOH
3.261
2.758
CA
N
O3'
O
6s35 1 O60341 99.4 0.0 X-RAY
2020-02-26 GLY A:148 A:315 6.0 0.08 T 59.0 -124.3 6.0 0.08 0.0 FAD
3.624
CA
O2A
5h6q 1 O60341 99.4 0.0 X-RAY
2017-04-12 GLY A:151 A:315 10.0 0.133 T 72.8 -117.3 10.0 0.133 0.0 GOL
FAD
HOH
5.688
3.479
6.712
O
CA
O
O3
O3B
O
5h6r 1 O60341 99.4 0.0 X-RAY
2017-04-12 GLY A:151 A:315 10.0 0.133 T 61.5 -113.7 10.0 0.133 0.0 FAD
GOL
HOH
3.233
5.574
2.908
CA
O
N
O3B
O3
O
5x60 1 O60341 99.4 0.0 X-RAY
2017-04-12 GLY A:151 A:315 10.0 0.133 T 66.6 -119.0 10.0 0.133 0.0 FAD
GOL
HOH
3.341
5.779
4.372
CA
O
C
O3B
O3
O
5yjb 1 O60341 99.4 0.0 X-RAY
2018-07-04 GLY A:151 A:315 11.0 0.147 T 55.8 -126.9 11.0 0.147 0.0 FAD
GOL
3.197
5.817
CA
O
O3B
O3
6kgk 1 O60341 99.4 0.0 X-RAY
2020-03-25 GLY A:151 A:315 11.0 0.147 T 58.0 -122.4 11.0 0.147 0.0 GOL
FAD
HOH
5.891
3.178
4.165
O
CA
CA
C3
O3B
O
6kgl 1 O60341 99.4 0.0 X-RAY
2020-03-25 GLY A:151 A:315 11.0 0.147 T 58.4 -121.2 11.0 0.147 0.0 GOL
FAD
HOH
5.849
3.193
4.141
O
CA
CA
C3
O3B
O
6kgm 1 O60341 99.4 0.0 X-RAY
2020-03-25 GLY A:151 A:315 12.0 0.16 T 55.8 -118.0 12.0 0.16 0.0 GOL
FAD
HOH
5.800
3.196
4.080
O
CA
CA
O3
O3B
O
6kgn 1 O60341 99.4 0.0 X-RAY
2020-03-25 GLY A:151 A:315 12.0 0.16 T 55.6 -117.7 12.0 0.16 0.0 GOL
FAD
HOH
5.798
3.204
4.097
O
CA
CA
O3
O3B
O
6kgo 1 O60341 99.4 0.0 X-RAY
2020-03-25 GLY A:151 A:315 11.0 0.147 T 55.1 -112.8 11.0 0.147 0.0 GOL
GOL
FAD
HOH
5.297
8.177
3.236
2.757
O
N
CA
N
O3
O2
O3B
O
6kgp 1 O60341 99.4 0.0 X-RAY
2020-03-25 GLY A:151 A:315 11.0 0.147 T 55.4 -112.9 11.0 0.147 0.0 GOL
GOL
FAD
HOH
5.305
8.165
3.244
2.766
O
N
CA
N
O3
O2
O3B
O
6kgq 1 O60341 99.4 0.0 X-RAY
2020-03-25 GLY A:151 A:315 11.0 0.147 T 55.6 -111.8 11.0 0.147 0.0 FAD
HOH
3.222
2.749
CA
N
O3B
O
6kgr 1 O60341 99.4 0.0 X-RAY
2020-03-25 GLY A:151 A:315 11.0 0.147 T 55.2 -111.9 11.0 0.147 0.0 FAD
HOH
3.225
2.760
CA
N
O3B
O
7cdc 1 O60341 99.4 0.0 X-RAY
2021-06-23 GLY A:151 A:315 9.0 0.12 T 62.6 -113.0 9.0 0.12 0.0 FAD
GOL
HOH
3.299
5.752
4.677
CA
O
CA
O3B
O3
O
7cdd 1 O60341 99.4 0.0 X-RAY
2021-06-23 GLY A:151 A:315 9.0 0.12 T 64.2 -116.4 9.0 0.12 0.0 FAD
GOL
HOH
3.358
5.690
6.669
CA
O
CA
O3B
C3
O
7cde 1 O60341 99.4 0.0 X-RAY
2021-06-23 GLY A:151 A:315 10.0 0.133 T 64.5 -116.3 10.0 0.133 0.0 FAD
GOL
HOH
3.352
5.605
6.988
CA
O
O
O3B
C3
O
7cdf 1 O60341 99.4 0.0 X-RAY
2021-06-23 GLY A:151 A:315 9.0 0.12 T 61.4 -115.0 9.0 0.12 0.0 FAD
GOL
HOH
3.277
5.817
6.721
CA
O
CA
O3B
C3
O
7cdg 1 O60341 99.4 0.0 X-RAY
2021-06-23 GLY A:151 A:315 9.0 0.12 T 57.7 -117.3 9.0 0.12 0.0 FAD
GOL
HOH
3.295
5.904
7.157
CA
O
O
O3B
C3
O
2ejr 1 O60341 99.4 0.0 X-RAY
2008-01-01 GLY A:144 A:315 11.0 0.147 T 56.9 -117.2 11.0 0.147 0.0 F2N
HOH
3.273
2.577
CA
N
O3'
O
2z3y 1 O60341 99.4 0.0 X-RAY
2008-01-01 GLY A:144 A:315 11.0 0.147 T 58.6 -114.6 11.0 0.147 0.0 F2N
HOH
3.256
2.738
CA
N
O3'
O
2z5u 1 O60341 99.4 0.0 X-RAY
2008-04-01 GLY A:144 A:315 10.0 0.133 T 56.2 -113.1 10.0 0.133 0.0 FAJ
HOH
3.162
2.655
CA
N
O15
O
3abt 1 O60341 99.4 0.0 X-RAY
2010-07-07 GLY A:144 A:315 9.0 0.12 S 56.7 -117.6 9.0 0.12 0.0 2PF
3.588
CA
C3'
3abu 1 O60341 99.4 0.0 X-RAY
2010-07-07 GLY A:144 A:315 10.0 0.133 T 56.3 -117.6 10.0 0.133 0.0 12F
3.296
CA
O3'
6k3e 1 O60341 99.4 0.0 X-RAY
2020-05-20 GLY A:144 A:315 9.0 0.12 T 55.4 -113.0 9.0 0.12 0.0 MLA
D3U
HOH
5.622
3.505
8.400
O
CA
CA
O1B
O3'
O
2dw4 1 O60341 99.4 0.0 X-RAY
2007-09-04 GLY A:144 A:315 11.0 0.147 T 52.7 -114.1 11.0 0.147 0.0 FAD
HOH
3.309
2.903
CA
N
O3B
O
6w4k 1 O60341 99.4 0.0 X-RAY
2020-10-21 GLY A:142 A:315 10.0 0.133 T 63.3 -122.4 10.0 0.133 0.0 FAD
HOH
3.123
2.911
CA
N
O2A
O
6nqm 1 O60341 99.4 0.0 X-RAY
2019-02-13 GLY A:143 A:315 11.0 0.147 T 61.1 -112.9 11.0 0.147 0.0 FAD
2.443
HA3
H3B
6nqu 1 O60341 99.4 0.0 X-RAY
2019-02-13 GLY A:143 A:315 12.0 0.16 T 62.1 -114.0 12.0 0.16 0.0 KWM
3.167
CA
O15
6nr5 1 O60341 99.4 0.0 X-RAY
2019-07-17 GLY A:143 A:315 9.0 0.12 T 63.5 -109.6 9.0 0.12 0.0 KXM
2.940
CA
O15

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 GLY A:315 A:315 9.0 0.12 T 59.5 -107.0