Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23384040 . A C CCDS30627.1:NM_015013.3:c.994Atg>Ctg_NP_055828.2:p.332M>L Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
 2013-06-12 MET A:352 A:332 8.0 0.043 -137.7 -41.3 8.0 0.043 0.0 FAD
 3.133
 N
 O4
3zmv 1 O60341 99.54 0.0 X-RAY
 2013-06-12 MET A:352 A:332 9.0 0.049 -124.2 -37.9 9.0 0.049 0.0 FAD
 3.116
 N
 O4
3zms 1 O60341 99.43 0.0 X-RAY
 2013-06-12 MET A:352 A:332 8.0 0.043 -136.0 -37.9 8.0 0.043 0.0 FAD
 3.230
 N
 O4
3zmt 1 O60341 99.43 0.0 X-RAY
 2013-06-12 MET A:352 A:332 9.0 0.049 -139.6 -33.5 9.0 0.049 0.0 FAD
 3.185
 N
 O4
3zmz 1 O60341 99.43 0.0 X-RAY
 2013-06-12 MET A:352 A:332 8.0 0.043 -141.0 -39.4 8.0 0.043 0.0 FAD
 3.234
 N
 O4
3zn0 1 O60341 99.43 0.0 X-RAY
 2013-06-12 MET A:352 A:332 9.0 0.049 -139.6 -39.5 9.0 0.049 0.0 FAD
 3.125
 N
 O4
3zn1 1 O60341 99.43 0.0 X-RAY
 2013-06-12 MET A:352 A:332 8.0 0.043 -143.1 -36.3 8.0 0.043 0.0 FAD
 3.140
 N
 O4
4czz 1 O60341 99.43 0.0 X-RAY
 2014-06-11 MET A:352 A:332 6.0 0.032 -130.0 -4.2 6.0 0.032 0.0 FAD
 3.252
 N
 O4
4uv8 1 O60341 99.43 0.0 X-RAY
 2014-09-10 MET A:352 A:332 9.0 0.049 -144.1 -31.4 9.0 0.049 0.0 D69
HOH
 3.263
3.578
 N
CE
 O4
O
4uv9 1 O60341 99.43 0.0 X-RAY
 2014-09-10 MET A:352 A:332 5.0 0.027 -144.3 -32.4 5.0 0.027 0.0 D70
 3.143
 N
 O4
4uva 1 O60341 99.43 0.0 X-RAY
 2014-09-10 MET A:352 A:332 10.0 0.054 -140.2 -30.7 10.0 0.054 0.0 D73
HOH
 3.199
3.733
 N
CE
 O4
O
4uvb 1 O60341 99.43 0.0 X-RAY
 2014-09-10 MET A:352 A:332 12.0 0.065 -144.8 -32.9 12.0 0.065 0.0 D51
 3.011
 N
 O4
4uvc 1 O60341 99.43 0.0 X-RAY
 2014-09-10 MET A:352 A:332 10.0 0.054 -145.6 -13.7 10.0 0.054 0.0 D52
 3.026
 N
 O4
6tuy 1 O60341 94.98 0.0 X-RAY
 2021-07-21 MET A:332 A:332 21.0 0.114 -133.9 -32.7 21.0 0.114 0.0 FAD
NY8
NY8
 3.305
6.615
9.864
 N
N
N
 O4
CAE
CAH
2xaf 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:332 A:332 8.0 0.043 -162.2 -38.9 8.0 0.043 0.0 FAD
TCF
 3.368
3.230
 N
CE
 O4
O1B
2xag 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:332 A:332 6.0 0.032 -139.8 -11.9 6.0 0.032 0.0 FAD
TCF
 3.030
3.495
 N
CE
 O4
O1B
2xah 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:332 A:332 10.0 0.054 -152.5 -28.2 10.0 0.054 0.0 FAD
3PL
 2.960
3.292
 N
CE
 O4
CE1
2xaj 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:332 A:332 7.0 0.038 -155.3 -39.1 7.0 0.038 0.0 FAD
TCA
 2.968
3.529
 N
CE
 O4
O
2xaq 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:332 A:332 7.0 0.038 -164.3 -41.3 7.0 0.038 0.0 FAD
M84
 3.404
4.076
 N
CB
 O4
O1B
2xas 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:332 A:332 7.0 0.038 -157.7 -24.6 7.0 0.038 0.0 FAD
M80
 2.948
3.525
 N
CE
 O4
O1B
4uxn 1 O60341 94.98 0.0 X-RAY
 2015-02-25 MET A:332 A:332 0.0 0.0 -137.7 -27.7 0.0 0.0 0.0 FAD
M8A
 2.983
3.923
 N
CB
 O4
OAA
5lhg 1 O60341 94.98 0.0 X-RAY
 2017-02-22 MET A:332 A:332 12.0 0.065 -144.4 -30.4 12.0 0.065 0.0 FAD
6X3
6X3
HOH
 3.159
4.372
8.795
3.493
 N
CE
CE
CE
 O4
O11
C19
O
5lhh 1 O60341 94.98 0.0 X-RAY
 2017-02-22 MET A:332 A:332 5.0 0.027 -150.9 0.5 5.0 0.027 0.0 FAD
6X0
HOH
 3.263
5.051
3.154
 N
SD
CE
 O4
C15
O
5lhi 1 O60341 94.98 0.0 X-RAY
 2017-02-22 MET A:332 A:332 9.0 0.049 -114.5 -60.1 9.0 0.049 0.0 FAD
6X5
HOH
 3.158
4.850
3.360
 N
CE
CG
 O4
O28
O
6te1 1 O60341 94.98 0.0 X-RAY
 2020-06-03 MET A:332 A:332 6.0 0.032 71.4 9.3 6.0 0.032 0.0 N4K
N4K
FAD
HOH
 9.508
3.232
4.123
4.939
 O
CE
N
CG
 S34
C09
O4
O
5l3c 1 O60341 94.86 0.0 X-RAY
 2016-05-04 MET A:332 A:332 8.0 0.043 -134.1 -26.2 8.0 0.043 0.0 FAD
 3.244
 N
 O4
5l3d 1 O60341 94.86 0.0 X-RAY
 2016-05-04 MET A:332 A:332 8.0 0.043 -139.7 -4.6 8.0 0.043 0.0 FAD
HOH
 3.528
9.232
 N
CE
 O4
O
5l3b 1 O60341 94.86 0.0 X-RAY
 2016-05-04 MET A:332 A:332 7.0 0.038 -137.0 -33.9 7.0 0.038 0.0 FAD
 3.224
 N
 O4
2x0l 1 O60341 100.0 0.0 X-RAY
 2010-03-02 MET A:210 A:332 9.0 0.049 -142.7 -29.1 9.0 0.049 0.0 FAD
 2.999
 N
 O4
4bay 1 O60341 99.85 0.0 X-RAY
 2013-11-27 MET A:162 A:332 12.0 0.065 -136.5 -34.1 12.0 0.065 0.0 FAD
 3.329
 N
 O4
2v1d 1 O60341 99.42 0.0 X-RAY
 2007-05-29 MET A:210 A:332 5.0 0.027 -144.2 -31.1 5.0 0.027 0.0 FAD
 3.088
 N
 O4
2y48 1 O60341 99.42 0.0 X-RAY
 2011-02-16 MET A:210 A:332 10.0 0.054 -136.0 -28.6 10.0 0.054 0.0 FAD
 2.999
 N
 O4
5l3e 1 O60341 99.42 0.0 X-RAY
 2016-09-21 MET A:210 A:332 6.0 0.032 -131.6 -32.9 6.0 0.032 0.0 FAD
E11
 3.307
7.313
 N
CE
 O4
CBG
5l3f 1 O60341 99.42 0.0 X-RAY
 2016-09-21 MET A:210 A:332 7.0 0.038 -152.3 -24.4 7.0 0.038 0.0 FAD
 2.900
 N
 O4
5l3g 1 O60341 99.42 0.0 X-RAY
 2016-09-21 MET A:210 A:332 11.0 0.059 -130.6 -32.7 9.0 0.049 0.01 C:None:0.011
 FAD
 2.935
 N
 O4
5lbq 1 O60341 99.42 0.0 X-RAY
 2016-09-21 MET A:210 A:332 6.0 0.032 -127.9 -27.3 6.0 0.032 0.0 FAD
 3.141
 N
 O4
5lgt 1 O60341 99.42 0.0 X-RAY
 2017-02-22 MET A:210 A:332 5.0 0.027 -137.3 -26.0 5.0 0.027 0.0 FAD
6W3
 3.248
4.096
 N
CE
 O4
CAH
5lgu 1 O60341 99.42 0.0 X-RAY
 2017-02-22 MET A:210 A:332 6.0 0.032 -140.5 -15.3 6.0 0.032 0.0 FAD
6W1
 3.148
4.434
 N
CE
 O4
C4
6vyp 7 O60341 98.69 0.0 X-RAY
 2020-05-27 MET S:164 M:332 21.0 0.114 -157.4 -7.5 21.0 0.114 0.0 FAD
 4.563
 N
 O4
MET U:164 m:332 25.0 0.135 -159.2 -8.6 NA NA NA
MET W:164 K:332 11.0 0.059 -159.3 -37.5 11.0 0.059 0.0 FAD
 2.815
 N
 O4
MET Y:164 k:332 5.0 0.027 -153.8 -13.9 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
 2017-02-22 MET A:162 A:332 12.0 0.065 -145.1 -16.3 12.0 0.065 0.0 FAD
6W0
 3.051
5.016
 N
CE
 O4
CAG
2iw5 1 O60341 99.4 0.0 X-RAY
 2006-08-09 MET A:162 A:332 9.0 0.049 -142.0 -30.9 9.0 0.049 0.0 FAD
GOL
HOH
 3.212
8.841
3.573
 N
CE
CE
 O4
O3
O
2uxn 1 O60341 99.4 0.0 X-RAY
 2007-05-29 MET A:162 A:332 11.0 0.059 -140.2 -34.9 8.0 0.043 0.016 C:P68431:0.016
 FDA
HOH
 2.993
4.844
 N
N
 O4
O
2uxx 1 O60341 99.4 0.0 X-RAY
 2007-08-21 MET A:162 A:332 6.0 0.032 -144.9 -25.0 6.0 0.032 0.0 FAJ
GOL
HOH
 2.704
8.358
4.776
 N
CE
N
 O1
C3
O
4kum 1 O60341 99.4 0.0 X-RAY
 2014-05-07 MET A:162 A:332 8.0 0.043 -140.8 -29.8 8.0 0.043 0.0 FAD
THG
HOH
 3.096
5.499
8.703
 N
CE
CE
 O4
O11
O
4xbf 1 O60341 99.4 0.0 X-RAY
 2016-04-27 MET A:162 A:332 13.0 0.07 -143.3 -35.5 13.0 0.07 0.0 FAD
HOH
 2.527
4.983
 H
N
 O4
O
6wc6 1 O60341 99.4 0.0 X-RAY
 2021-06-30 MET A:162 A:332 7.0 0.038 -130.6 -0.2 7.0 0.038 0.0 FAD
 3.177
 N
 O4
2h94 1 O60341 99.4 0.0 X-RAY
 2006-07-04 MET A:161 A:332 9.0 0.049 -142.0 -40.9 9.0 0.049 0.0 FAD
HOH
 3.211
3.693
 N
CE
 O4
O
2hko 1 O60341 99.25 0.0 X-RAY
 2006-08-29 MET A:161 A:332 12.0 0.065 -129.2 -33.9 12.0 0.065 0.0 FAD
HOH
 3.306
3.620
 N
CE
 O4
O
7e0g 1 O60341 99.1 0.0 X-RAY
 2021-03-24 MET A:164 A:332 17.0 0.092 -143.0 -10.5 17.0 0.092 0.0 HUF
IMD
HOH
 3.065
3.481
3.481
 N
CG
SD
 O35
N1
O
6s35 1 O60341 99.4 0.0 X-RAY
 2020-02-26 MET A:165 A:332 16.0 0.086 -139.6 -30.0 16.0 0.086 0.0 FAD
 3.191
 N
 O4
5h6q 1 O60341 99.4 0.0 X-RAY
 2017-04-12 MET A:168 A:332 8.0 0.043 -131.6 -27.0 8.0 0.043 0.0 FAD
 3.228
 N
 O4
5h6r 1 O60341 99.4 0.0 X-RAY
 2017-04-12 MET A:168 A:332 6.0 0.032 -141.0 -19.7 6.0 0.032 0.0 FAD
HOH
 3.517
4.822
 N
N
 O4
O
5x60 1 O60341 99.4 0.0 X-RAY
 2017-04-12 MET A:168 A:332 9.0 0.049 -128.2 -30.4 9.0 0.049 0.0 FAD
HOH
 3.382
5.824
 N
C
 O4
O
5yjb 1 O60341 99.4 0.0 X-RAY
 2018-07-04 MET A:168 A:332 16.0 0.086 -146.6 -17.6 16.0 0.086 0.0 FAD
8WC
 2.848
3.303
 N
SD
 O4
N
6kgk 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:168 A:332 8.0 0.043 -146.9 -11.9 8.0 0.043 0.0 GOL
DJ0
FAD
HOH
 6.958
3.474
2.792
3.711
 CE
CG
N
CB
 O2
O15
O4
O
6kgl 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:168 A:332 8.0 0.043 -146.4 -11.1 8.0 0.043 0.0 GOL
DJ0
FAD
HOH
 6.995
3.843
2.788
3.598
 CE
CE
N
CB
 O2
O15
O4
O
6kgm 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:168 A:332 7.0 0.038 -135.7 -14.8 7.0 0.038 0.0 GOL
DJ0
FAD
HOH
 7.458
3.609
2.765
4.812
 CE
CE
N
N
 O3
O15
O4
O
6kgn 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:168 A:332 8.0 0.043 -136.0 -15.0 8.0 0.043 0.0 GOL
DJ0
FAD
HOH
 7.484
3.937
2.740
4.800
 CE
CE
N
N
 O3
O15
O4
O
6kgo 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:168 A:332 10.0 0.054 -142.1 -11.2 10.0 0.054 0.0 GOL
DJ0
FAD
HOH
 8.332
3.631
2.784
3.511
 CE
CE
N
CB
 O1
O15
O4
O
6kgp 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:168 A:332 10.0 0.054 -141.6 -11.4 10.0 0.054 0.0 GOL
DJ0
FAD
HOH
 8.327
3.903
2.800
3.513
 CE
CE
N
CB
 O1
O15
O4
O
6kgq 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:168 A:332 6.0 0.032 -139.7 -13.1 6.0 0.032 0.0 MPD
DJC
FAD
HOH
 6.591
3.771
2.933
3.447
 CE
CE
N
CB
 CM
O15
O4
O
6kgr 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:168 A:332 6.0 0.032 -138.9 -12.7 6.0 0.032 0.0 MPD
DJC
FAD
HOH
 6.588
4.069
2.985
3.451
 CE
CE
N
CB
 CM
O15
O4
O
7cdc 1 O60341 99.4 0.0 X-RAY
 2021-06-23 MET A:168 A:332 8.0 0.043 -137.2 -33.7 8.0 0.043 0.0 FAD
HOH
 3.412
6.270
 N
C
 O4
O
7cdd 1 O60341 99.4 0.0 X-RAY
 2021-06-23 MET A:168 A:332 8.0 0.043 -134.6 -29.8 8.0 0.043 0.0 FAD
HOH
 3.301
7.649
 N
CE
 O4
O
7cde 1 O60341 99.4 0.0 X-RAY
 2021-06-23 MET A:168 A:332 7.0 0.038 -134.8 -34.7 7.0 0.038 0.0 FAD
GOL
 3.295
7.330
 N
CE
 O4
C3
7cdf 1 O60341 99.4 0.0 X-RAY
 2021-06-23 MET A:168 A:332 7.0 0.038 -136.6 -33.6 7.0 0.038 0.0 FAD
HOH
 3.333
7.487
 N
CE
 O4
O
7cdg 1 O60341 99.4 0.0 X-RAY
 2021-06-23 MET A:168 A:332 9.0 0.049 -135.3 -30.8 9.0 0.049 0.0 FAD
GOL
 3.356
9.151
 N
CE
 O4
O3
2ejr 1 O60341 99.4 0.0 X-RAY
 2008-01-01 MET A:161 A:332 8.0 0.043 -146.3 -12.5 8.0 0.043 0.0 F2N
HOH
 3.046
3.652
 N
CB
 OBB
O
2z3y 1 O60341 99.4 0.0 X-RAY
 2008-01-01 MET A:161 A:332 9.0 0.049 -143.4 -19.4 9.0 0.049 0.0 F2N
HOH
 2.944
3.717
 N
CB
 OBB
O
2z5u 1 O60341 99.4 0.0 X-RAY
 2008-04-01 MET A:161 A:332 9.0 0.049 -137.2 -16.2 9.0 0.049 0.0 FAJ
HOH
 3.100
3.519
 N
CB
 O1
O
3abt 1 O60341 99.4 0.0 X-RAY
 2010-07-07 MET A:161 A:332 10.0 0.054 -158.7 -7.6 10.0 0.054 0.0 2PF
 2.875
 CG
 OCC
3abu 1 O60341 99.4 0.0 X-RAY
 2010-07-07 MET A:161 A:332 8.0 0.043 -146.4 -21.4 8.0 0.043 0.0 12F
 3.191
 CG
 OCQ
6k3e 1 O60341 99.4 0.0 X-RAY
 2020-05-20 MET A:161 A:332 5.0 0.027 -135.2 -11.9 5.0 0.027 0.0 CW0
D3U
CVO
 7.222
3.012
6.618
 SD
N
SD
 C17
OAL
N19
2dw4 1 O60341 99.4 0.0 X-RAY
 2007-09-04 MET A:161 A:332 14.0 0.076 -135.2 -26.6 14.0 0.076 0.0 FAD
HOH
 3.083
3.546
 N
N
 O4
O
6w4k 1 O60341 99.4 0.0 X-RAY
 2020-10-21 MET A:159 A:332 12.0 0.065 -136.0 -7.2 12.0 0.065 0.0 V0Y
FAD
HOH
 3.345
3.039
4.625
 CG
N
N
 F13
O4
O
6nqm 1 O60341 99.4 0.0 X-RAY
 2019-02-13 MET A:160 A:332 8.0 0.043 -142.3 -18.8 8.0 0.043 0.0 FAD
 2.552
 H
 O4
6nqu 1 O60341 99.4 0.0 X-RAY
 2019-02-13 MET A:160 A:332 9.0 0.049 -144.8 -3.4 9.0 0.049 0.0 KWM
 3.656
 CE
 O3
6nr5 1 O60341 99.4 0.0 X-RAY
 2019-07-17 MET A:160 A:332 9.0 0.049 -142.5 -22.2 9.0 0.049 0.0 KXM
 3.492
 N
 O1

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 MET A:332 A:332 6.0 0.032 -131.3 -18.4