Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23385583 . G A CCDS30627.1:NM_015013.3:c.1030Gtg>Atg_NP_055828.2:p.344V>M Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
 2013-06-12 VAL A:364 A:344 6.0 0.039 H -66.2 -47.1 6.0 0.039 0.0
3zmv 1 O60341 99.54 0.0 X-RAY
 2013-06-12 VAL A:364 A:344 8.0 0.052 H -62.4 -54.5 8.0 0.052 0.0
3zms 1 O60341 99.43 0.0 X-RAY
 2013-06-12 VAL A:364 A:344 6.0 0.039 H -63.8 -49.6 6.0 0.039 0.0
3zmt 1 O60341 99.43 0.0 X-RAY
 2013-06-12 VAL A:364 A:344 5.0 0.032 H -64.5 -50.7 5.0 0.032 0.0
3zmz 1 O60341 99.43 0.0 X-RAY
 2013-06-12 VAL A:364 A:344 4.0 0.026 H -63.7 -50.7 4.0 0.026 0.0
3zn0 1 O60341 99.43 0.0 X-RAY
 2013-06-12 VAL A:364 A:344 8.0 0.052 H -66.1 -44.6 8.0 0.052 0.0
3zn1 1 O60341 99.43 0.0 X-RAY
 2013-06-12 VAL A:364 A:344 7.0 0.045 H -66.2 -50.0 7.0 0.045 0.0
4czz 1 O60341 99.43 0.0 X-RAY
 2014-06-11 VAL A:364 A:344 5.0 0.032 H -51.8 -47.6 5.0 0.032 0.0
4uv8 1 O60341 99.43 0.0 X-RAY
 2014-09-10 VAL A:364 A:344 8.0 0.052 H -62.2 -47.8 8.0 0.052 0.0
4uv9 1 O60341 99.43 0.0 X-RAY
 2014-09-10 VAL A:364 A:344 6.0 0.039 H -68.6 -48.4 6.0 0.039 0.0
4uva 1 O60341 99.43 0.0 X-RAY
 2014-09-10 VAL A:364 A:344 8.0 0.052 H -66.7 -46.2 8.0 0.052 0.0
4uvb 1 O60341 99.43 0.0 X-RAY
 2014-09-10 VAL A:364 A:344 8.0 0.052 H -63.8 -49.8 8.0 0.052 0.0
4uvc 1 O60341 99.43 0.0 X-RAY
 2014-09-10 VAL A:364 A:344 6.0 0.039 H -60.0 -54.8 6.0 0.039 0.0
6tuy 1 O60341 94.98 0.0 X-RAY
 2021-07-21 VAL A:344 A:344 2.0 0.013 H -51.9 -45.1 2.0 0.013 0.0
2xaf 1 O60341 94.98 0.0 X-RAY
 2010-05-05 VAL A:344 A:344 5.0 0.032 H -71.9 -52.6 5.0 0.032 0.0
2xag 1 O60341 94.98 0.0 X-RAY
 2010-05-05 VAL A:344 A:344 4.0 0.026 H -49.9 -52.6 4.0 0.026 0.0
2xah 1 O60341 94.98 0.0 X-RAY
 2010-05-05 VAL A:344 A:344 6.0 0.039 H -60.3 -48.1 6.0 0.039 0.0
2xaj 1 O60341 94.98 0.0 X-RAY
 2010-05-05 VAL A:344 A:344 2.0 0.013 H -68.8 -57.6 2.0 0.013 0.0
2xaq 1 O60341 94.98 0.0 X-RAY
 2010-05-05 VAL A:344 A:344 8.0 0.052 H -54.5 -45.7 8.0 0.052 0.0
2xas 1 O60341 94.98 0.0 X-RAY
 2010-05-05 VAL A:344 A:344 4.0 0.026 H -65.4 -55.1 4.0 0.026 0.0
4uxn 1 O60341 94.98 0.0 X-RAY
 2015-02-25 VAL A:344 A:344 3.0 0.019 H -59.0 -45.7 3.0 0.019 0.0
5lhg 1 O60341 94.98 0.0 X-RAY
 2017-02-22 VAL A:344 A:344 4.0 0.026 H -76.6 -40.5 4.0 0.026 0.0
5lhh 1 O60341 94.98 0.0 X-RAY
 2017-02-22 VAL A:344 A:344 6.0 0.039 H -66.6 -42.0 6.0 0.039 0.0 HOH
 9.832
 N
 O
5lhi 1 O60341 94.98 0.0 X-RAY
 2017-02-22 VAL A:344 A:344 3.0 0.019 H -82.1 -33.4 3.0 0.019 0.0
6te1 1 O60341 94.98 0.0 X-RAY
 2020-06-03 VAL A:344 A:344 6.0 0.039 H -72.8 -42.0 6.0 0.039 0.0 HOH
 9.945
 N
 O
5l3c 1 O60341 94.86 0.0 X-RAY
 2016-05-04 VAL A:344 A:344 7.0 0.045 H -63.4 -42.3 7.0 0.045 0.0
5l3d 1 O60341 94.86 0.0 X-RAY
 2016-05-04 VAL A:344 A:344 7.0 0.045 H -60.9 -41.1 7.0 0.045 0.0 HOH
 8.974
 CG2
 O
5l3b 1 O60341 94.86 0.0 X-RAY
 2016-05-04 VAL A:344 A:344 3.0 0.019 H -58.7 -40.2 3.0 0.019 0.0
2x0l 1 O60341 100.0 0.0 X-RAY
 2010-03-02 VAL A:222 A:344 3.0 0.019 H -57.5 -50.1 3.0 0.019 0.0
4bay 1 O60341 99.85 0.0 X-RAY
 2013-11-27 VAL A:174 A:344 3.0 0.019 H -66.5 -52.0 3.0 0.019 0.0
2v1d 1 O60341 99.42 0.0 X-RAY
 2007-05-29 VAL A:222 A:344 7.0 0.045 H -58.7 -54.6 7.0 0.045 0.0
2y48 1 O60341 99.42 0.0 X-RAY
 2011-02-16 VAL A:222 A:344 6.0 0.039 H -61.6 -44.8 6.0 0.039 0.0
5l3e 1 O60341 99.42 0.0 X-RAY
 2016-09-21 VAL A:222 A:344 4.0 0.026 H -56.3 -49.2 4.0 0.026 0.0
5l3f 1 O60341 99.42 0.0 X-RAY
 2016-09-21 VAL A:222 A:344 2.0 0.013 H -50.9 -54.7 2.0 0.013 0.0
5l3g 1 O60341 99.42 0.0 X-RAY
 2016-09-21 VAL A:222 A:344 3.0 0.019 H -53.9 -44.8 3.0 0.019 0.0
5lbq 1 O60341 99.42 0.0 X-RAY
 2016-09-21 VAL A:222 A:344 2.0 0.013 H -58.5 -53.4 2.0 0.013 0.0
5lgt 1 O60341 99.42 0.0 X-RAY
 2017-02-22 VAL A:222 A:344 2.0 0.013 H -61.1 -40.6 2.0 0.013 0.0
5lgu 1 O60341 99.42 0.0 X-RAY
 2017-02-22 VAL A:222 A:344 5.0 0.032 H -62.9 -39.7 5.0 0.032 0.0
6vyp 7 O60341 98.69 0.0 X-RAY
 2020-05-27 VAL S:176 M:344 6.0 0.039 H -63.0 -39.3 6.0 0.039 0.0
VAL U:176 m:344 8.0 0.052 H -63.4 -39.3 NA NA NA
VAL W:176 K:344 5.0 0.032 H -71.0 -37.7 5.0 0.032 0.0
VAL Y:176 k:344 7.0 0.045 H -78.4 -38.4 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
 2017-02-22 VAL A:174 A:344 6.0 0.039 H -58.1 -43.9 6.0 0.039 0.0
2iw5 1 O60341 99.4 0.0 X-RAY
 2006-08-09 VAL A:174 A:344 6.0 0.039 H -68.1 -47.8 6.0 0.039 0.0 HOH
 9.651
 N
 O
2uxn 1 O60341 99.4 0.0 X-RAY
 2007-05-29 VAL A:174 A:344 8.0 0.052 H -67.5 -45.2 8.0 0.052 0.0
2uxx 1 O60341 99.4 0.0 X-RAY
 2007-08-21 VAL A:174 A:344 7.0 0.045 H -71.8 -46.3 7.0 0.045 0.0
4kum 1 O60341 99.4 0.0 X-RAY
 2014-05-07 VAL A:174 A:344 3.0 0.019 H -68.1 -47.2 3.0 0.019 0.0
4xbf 1 O60341 99.4 0.0 X-RAY
 2016-04-27 VAL A:174 A:344 2.0 0.013 H -65.8 -45.5 2.0 0.013 0.0
6wc6 1 O60341 99.4 0.0 X-RAY
 2021-06-30 VAL A:174 A:344 2.0 0.013 H -56.9 -46.4 2.0 0.013 0.0
2h94 1 O60341 99.4 0.0 X-RAY
 2006-07-04 VAL A:173 A:344 2.0 0.013 H -75.4 -57.6 2.0 0.013 0.0
2hko 1 O60341 99.25 0.0 X-RAY
 2006-08-29 VAL A:173 A:344 8.0 0.052 H -61.3 -59.7 8.0 0.052 0.0 HOH
 4.960
 N
 O
7e0g 1 O60341 99.1 0.0 X-RAY
 2021-03-24 VAL A:176 A:344 6.0 0.039 H -64.9 -49.3 6.0 0.039 0.0 HOH
 3.773
 CG2
 O
6s35 1 O60341 99.4 0.0 X-RAY
 2020-02-26 VAL A:177 A:344 2.0 0.013 H -68.5 -48.0 2.0 0.013 0.0
5h6q 1 O60341 99.4 0.0 X-RAY
 2017-04-12 VAL A:180 A:344 3.0 0.019 H -56.3 -44.0 3.0 0.019 0.0
5h6r 1 O60341 99.4 0.0 X-RAY
 2017-04-12 VAL A:180 A:344 3.0 0.019 H -59.9 -49.9 3.0 0.019 0.0 HOH
 9.859
 N
 O
5x60 1 O60341 99.4 0.0 X-RAY
 2017-04-12 VAL A:180 A:344 3.0 0.019 H -65.4 -44.0 3.0 0.019 0.0 HOH
 9.892
 N
 O
5yjb 1 O60341 99.4 0.0 X-RAY
 2018-07-04 VAL A:180 A:344 3.0 0.019 H -67.2 -46.4 3.0 0.019 0.0
6kgk 1 O60341 99.4 0.0 X-RAY
 2020-03-25 VAL A:180 A:344 1.0 0.006 H -60.1 -45.8 1.0 0.006 0.0 HOH
 5.337
 CG2
 O
6kgl 1 O60341 99.4 0.0 X-RAY
 2020-03-25 VAL A:180 A:344 1.0 0.006 H -60.0 -45.7 1.0 0.006 0.0 HOH
 5.341
 CG2
 O
6kgm 1 O60341 99.4 0.0 X-RAY
 2020-03-25 VAL A:180 A:344 2.0 0.013 H -59.9 -47.6 2.0 0.013 0.0 HOH
 9.749
 N
 O
6kgn 1 O60341 99.4 0.0 X-RAY
 2020-03-25 VAL A:180 A:344 2.0 0.013 H -59.8 -47.7 2.0 0.013 0.0 HOH
 9.748
 N
 O
6kgo 1 O60341 99.4 0.0 X-RAY
 2020-03-25 VAL A:180 A:344 3.0 0.019 H -70.1 -47.8 3.0 0.019 0.0 HOH
 3.582
 CG2
 O
6kgp 1 O60341 99.4 0.0 X-RAY
 2020-03-25 VAL A:180 A:344 3.0 0.019 H -69.9 -48.0 3.0 0.019 0.0 HOH
 3.592
 CG2
 O
6kgq 1 O60341 99.4 0.0 X-RAY
 2020-03-25 VAL A:180 A:344 7.0 0.045 H -69.1 -48.7 7.0 0.045 0.0 HOH
 4.079
 CG2
 O
6kgr 1 O60341 99.4 0.0 X-RAY
 2020-03-25 VAL A:180 A:344 7.0 0.045 H -68.6 -48.7 7.0 0.045 0.0 HOH
 4.068
 CG2
 O
7cdc 1 O60341 99.4 0.0 X-RAY
 2021-06-23 VAL A:180 A:344 7.0 0.045 H -60.0 -46.2 7.0 0.045 0.0 HOH
 3.975
 CG2
 O
7cdd 1 O60341 99.4 0.0 X-RAY
 2021-06-23 VAL A:180 A:344 3.0 0.019 H -59.8 -45.1 3.0 0.019 0.0 HOH
 4.055
 CG2
 O
7cde 1 O60341 99.4 0.0 X-RAY
 2021-06-23 VAL A:180 A:344 9.0 0.058 H -59.3 -45.9 9.0 0.058 0.0 HOH
 3.876
 CG2
 O
7cdf 1 O60341 99.4 0.0 X-RAY
 2021-06-23 VAL A:180 A:344 3.0 0.019 H -61.8 -46.2 3.0 0.019 0.0 HOH
 8.850
 O
 O
7cdg 1 O60341 99.4 0.0 X-RAY
 2021-06-23 VAL A:180 A:344 2.0 0.013 H -62.0 -44.1 2.0 0.013 0.0
2ejr 1 O60341 99.4 0.0 X-RAY
 2008-01-01 VAL A:173 A:344 8.0 0.052 H -69.9 -50.6 8.0 0.052 0.0 HOH
 3.970
 CG2
 O
2z3y 1 O60341 99.4 0.0 X-RAY
 2008-01-01 VAL A:173 A:344 7.0 0.045 H -75.0 -50.0 7.0 0.045 0.0 HOH
 4.045
 CG2
 O
2z5u 1 O60341 99.4 0.0 X-RAY
 2008-04-01 VAL A:173 A:344 7.0 0.045 H -70.6 -48.4 7.0 0.045 0.0 HOH
 4.128
 CG2
 O
3abt 1 O60341 99.4 0.0 X-RAY
 2010-07-07 VAL A:173 A:344 7.0 0.045 H -69.6 -51.5 7.0 0.045 0.0
3abu 1 O60341 99.4 0.0 X-RAY
 2010-07-07 VAL A:173 A:344 6.0 0.039 H -60.5 -60.5 6.0 0.039 0.0
6k3e 1 O60341 99.4 0.0 X-RAY
 2020-05-20 VAL A:173 A:344 2.0 0.013 H -62.7 -50.0 2.0 0.013 0.0
2dw4 1 O60341 99.4 0.0 X-RAY
 2007-09-04 VAL A:173 A:344 4.0 0.026 H -68.5 -51.5 4.0 0.026 0.0 HOH
 4.044
 CG2
 O
6w4k 1 O60341 99.4 0.0 X-RAY
 2020-10-21 VAL A:171 NA:NA DO NA DO DO DO NA NA NA
6nqm 1 O60341 99.4 0.0 X-RAY
 2019-02-13 VAL A:172 A:344 6.0 0.039 H -51.2 -55.6 6.0 0.039 0.0
6nqu 1 O60341 99.4 0.0 X-RAY
 2019-02-13 VAL A:172 A:344 7.0 0.045 H -48.1 -56.0 7.0 0.045 0.0
6nr5 1 O60341 99.4 0.0 X-RAY
 2019-07-17 VAL A:172 A:344 10.0 0.065 H -61.5 -44.0 10.0 0.065 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 VAL A:344 A:344 5.0 0.032 H -79.7 -43.9