Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23395048 . A C CCDS30627.1:NM_015013.3:c.1124gAt>gCt_NP_055828.2:p.375D>A Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
 2013-06-12 ASP A:395 A:375 28.0 0.187 H -42.9 -59.8 28.0 0.187 0.0
3zmv 1 O60341 99.54 0.0 X-RAY
 2013-06-12 ASP A:395 A:375 26.0 0.173 H -39.7 -59.7 26.0 0.173 0.0
3zms 1 O60341 99.43 0.0 X-RAY
 2013-06-12 ASP A:395 A:375 29.0 0.193 H -42.7 -52.1 24.0 0.16 0.033 C:Q01101:0.033
3zmt 1 O60341 99.43 0.0 X-RAY
 2013-06-12 ASP A:395 A:375 31.0 0.207 H -40.7 -49.0 31.0 0.207 0.0
3zmz 1 O60341 99.43 0.0 X-RAY
 2013-06-12 ASP A:395 A:375 34.0 0.227 H -43.7 -34.5 34.0 0.227 0.0
3zn0 1 O60341 99.43 0.0 X-RAY
 2013-06-12 ASP A:395 A:375 34.0 0.227 H -43.9 -53.8 34.0 0.227 0.0
3zn1 1 O60341 99.43 0.0 X-RAY
 2013-06-12 ASP A:395 A:375 30.0 0.2 H -39.5 -61.5 30.0 0.2 0.0
4czz 1 O60341 99.43 0.0 X-RAY
 2014-06-11 ASP A:395 A:375 34.0 0.227 H -31.4 -55.6 34.0 0.227 0.0
4uv8 1 O60341 99.43 0.0 X-RAY
 2014-09-10 ASP A:395 A:375 30.0 0.2 H -63.4 11.6 30.0 0.2 0.0
4uv9 1 O60341 99.43 0.0 X-RAY
 2014-09-10 ASP A:395 A:375 31.0 0.207 H -36.5 -52.2 31.0 0.207 0.0
4uva 1 O60341 99.43 0.0 X-RAY
 2014-09-10 ASP A:395 A:375 31.0 0.207 H -59.2 -4.2 31.0 0.207 0.0
4uvb 1 O60341 99.43 0.0 X-RAY
 2014-09-10 ASP A:395 A:375 34.0 0.227 H -51.3 -26.6 34.0 0.227 0.0
4uvc 1 O60341 99.43 0.0 X-RAY
 2014-09-10 ASP A:395 A:375 34.0 0.227 H -35.9 -41.2 34.0 0.227 0.0
6tuy 1 O60341 94.98 0.0 X-RAY
 2021-07-21 ASP A:375 A:375 32.0 0.213 H -43.0 -49.0 32.0 0.213 0.0 HOH
 3.666
 OD1
 O
2xaf 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:375 A:375 32.0 0.213 H -28.9 -51.4 32.0 0.213 0.0
2xag 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:375 A:375 32.0 0.213 H -31.6 -64.1 32.0 0.213 0.0
2xah 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:375 A:375 30.0 0.2 H -31.9 -52.1 30.0 0.2 0.0
2xaj 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:375 A:375 29.0 0.193 H -21.6 -57.1 29.0 0.193 0.0
2xaq 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:375 A:375 30.0 0.2 H -33.2 -51.3 30.0 0.2 0.0
2xas 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:375 A:375 32.0 0.213 H -29.6 -46.3 32.0 0.213 0.0
4uxn 1 O60341 94.98 0.0 X-RAY
 2015-02-25 ASP A:375 A:375 29.0 0.193 H -45.3 -56.0 29.0 0.193 0.0
5lhg 1 O60341 94.98 0.0 X-RAY
 2017-02-22 ASP A:375 A:375 26.0 0.173 H -59.8 -30.2 26.0 0.173 0.0 6X3
 3.951
 OD2
 C34
5lhh 1 O60341 94.98 0.0 X-RAY
 2017-02-22 ASP A:375 A:375 31.0 0.207 H -56.1 -35.3 31.0 0.207 0.0
5lhi 1 O60341 94.98 0.0 X-RAY
 2017-02-22 ASP A:375 A:375 30.0 0.2 H -55.3 -53.6 30.0 0.2 0.0
6te1 1 O60341 94.98 0.0 X-RAY
 2020-06-03 ASP A:375 A:375 30.0 0.2 H -57.5 -37.0 30.0 0.2 0.0 N4K
 5.408
 OD1
 C09
5l3c 1 O60341 94.86 0.0 X-RAY
 2016-05-04 ASP A:375 A:375 35.0 0.233 H -38.7 -58.9 35.0 0.233 0.0
5l3d 1 O60341 94.86 0.0 X-RAY
 2016-05-04 ASP A:375 A:375 34.0 0.227 H -48.7 -42.4 34.0 0.227 0.0
5l3b 1 O60341 94.86 0.0 X-RAY
 2016-05-04 ASP A:375 A:375 26.0 0.173 H -49.6 -51.5 26.0 0.173 0.0
2x0l 1 O60341 100.0 0.0 X-RAY
 2010-03-02 ASP A:257 A:375 29.0 0.193 H -30.4 -57.7 17.0 0.113 0.08 C:Q5TEC6:0.08
4bay 1 O60341 99.85 0.0 X-RAY
 2013-11-27 ASP A:209 A:375 25.0 0.167 H -37.4 -49.0 25.0 0.167 0.0
2v1d 1 O60341 99.42 0.0 X-RAY
 2007-05-29 ASP A:253 A:375 30.0 0.2 H -29.0 -60.5 17.0 0.113 0.087 C:Q16695:0.087
2y48 1 O60341 99.42 0.0 X-RAY
 2011-02-16 ASP A:253 A:375 33.0 0.22 H -34.7 -47.5 23.0 0.153 0.067 C:O95863:0.067
5l3e 1 O60341 99.42 0.0 X-RAY
 2016-09-21 ASP A:253 A:375 30.0 0.2 H -44.4 -51.3 30.0 0.2 0.0
5l3f 1 O60341 99.42 0.0 X-RAY
 2016-09-21 ASP A:253 A:375 28.0 0.187 H -42.1 -63.0 28.0 0.187 0.0
5l3g 1 O60341 99.42 0.0 X-RAY
 2016-09-21 ASP A:253 A:375 32.0 0.213 H -39.2 -46.9 32.0 0.213 0.0
5lbq 1 O60341 99.42 0.0 X-RAY
 2016-09-21 ASP A:253 A:375 31.0 0.207 H -48.5 -50.4 31.0 0.207 0.0
5lgt 1 O60341 99.42 0.0 X-RAY
 2017-02-22 ASP A:253 A:375 29.0 0.193 H -34.9 -43.8 29.0 0.193 0.0
5lgu 1 O60341 99.42 0.0 X-RAY
 2017-02-22 ASP A:253 A:375 38.0 0.253 H -42.3 -54.3 38.0 0.253 0.0
6vyp 7 O60341 98.69 0.0 X-RAY
 2020-05-27 ASP S:207 M:375 27.0 0.18 H -63.4 -44.1 18.0 0.12 0.06 E:A0A310TTQ1:0.06
ASP U:207 m:375 28.0 0.187 H -63.2 -44.6 NA NA NA
ASP W:207 K:375 34.0 0.227 H -64.8 -36.6 21.0 0.14 0.087 A:A0A310TTQ1:0.087
ASP Y:207 k:375 125.0 0.833 S -143.9 162.1 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
 2017-02-22 ASP A:209 A:379 22.0 0.147 H -36.8 -63.0 22.0 0.147 0.0
2iw5 1 O60341 99.4 0.0 X-RAY
 2006-08-09 ASP A:205 A:375 38.0 0.253 H -36.7 -56.2 38.0 0.253 0.0 GOL
NH4
HOH
 9.494
4.511
7.931
 OD1
OD1
OD1
 O2
N
O
2uxn 1 O60341 99.4 0.0 X-RAY
 2007-05-29 ASP A:205 A:375 34.0 0.227 H -40.8 -49.5 34.0 0.227 0.0 HOH
 8.178
 OD1
 O
2uxx 1 O60341 99.4 0.0 X-RAY
 2007-08-21 ASP A:205 A:375 34.0 0.227 H -52.5 -48.9 34.0 0.227 0.0
4kum 1 O60341 99.4 0.0 X-RAY
 2014-05-07 ASP A:205 A:375 16.0 0.107 H -34.6 -55.7 16.0 0.107 0.0
4xbf 1 O60341 99.4 0.0 X-RAY
 2016-04-27 ASP A:205 A:375 31.0 0.207 H -53.7 -35.4 31.0 0.207 0.0 SO4
 9.351
 N
 O1
6wc6 1 O60341 99.4 0.0 X-RAY
 2021-06-30 ASP A:205 A:375 24.0 0.16 H -51.8 -46.3 24.0 0.16 0.0
2h94 1 O60341 99.4 0.0 X-RAY
 2006-07-04 ASP A:204 A:375 27.0 0.18 H -59.6 -32.8 27.0 0.18 0.0 HG
HOH
 5.636
7.550
 OD1
OD1
 HG
O
2hko 1 O60341 99.25 0.0 X-RAY
 2006-08-29 ASP A:204 A:375 31.0 0.207 H -66.7 -44.6 31.0 0.207 0.0 HOH
 3.092
 OD2
 O
7e0g 1 O60341 99.1 0.0 X-RAY
 2021-03-24 ASP A:207 A:375 28.0 0.187 H -51.3 -50.9 28.0 0.187 0.0 IMD
HOH
 2.781
2.824
 OD1
O
 N3
O
6s35 1 O60341 99.4 0.0 X-RAY
 2020-02-26 ASP A:208 A:375 42.0 0.28 H -35.2 -50.9 30.0 0.2 0.08 C:None:0.08
5h6q 1 O60341 99.4 0.0 X-RAY
 2017-04-12 ASP A:211 A:375 33.0 0.22 H -45.1 -52.4 21.0 0.14 0.08 C:None:0.08
 GOL
 9.233
 N
 O3
5h6r 1 O60341 99.4 0.0 X-RAY
 2017-04-12 ASP A:211 A:375 31.0 0.207 H -56.7 -44.0 17.0 0.113 0.094 C:None:0.093
5x60 1 O60341 99.4 0.0 X-RAY
 2017-04-12 ASP A:211 A:375 33.0 0.22 H -56.4 -47.1 22.0 0.147 0.073 C:None:0.073
 HOH
 9.263
 N
 O
5yjb 1 O60341 99.4 0.0 X-RAY
 2018-07-04 ASP A:211 A:375 33.0 0.22 H -53.5 -48.9 33.0 0.22 0.0
6kgk 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:211 A:375 32.0 0.213 H -55.2 -39.0 32.0 0.213 0.0
6kgl 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:211 A:375 32.0 0.213 H -54.7 -39.7 32.0 0.213 0.0
6kgm 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:211 A:375 35.0 0.233 H -55.5 -37.1 35.0 0.233 0.0 GOL
 9.806
 N
 O3
6kgn 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:211 A:375 35.0 0.233 H -55.2 -37.1 35.0 0.233 0.0 GOL
 9.809
 N
 O3
6kgo 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:211 A:375 31.0 0.207 H -53.0 -50.4 31.0 0.207 0.0 GOL
GOL
HOH
 8.614
2.257
4.409
 OD1
OD1
OD2
 O3
O2
O
6kgp 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:211 A:375 30.0 0.2 H -53.2 -50.6 30.0 0.2 0.0 GOL
GOL
HOH
 8.634
2.253
4.392
 OD1
OD1
OD2
 C3
O2
O
6kgq 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:211 A:375 34.0 0.227 H -58.2 -39.6 34.0 0.227 0.0 HOH
 7.926
 O
 O
6kgr 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:211 A:375 34.0 0.227 H -58.0 -39.6 34.0 0.227 0.0 HOH
 7.928
 O
 O
7cdc 1 O60341 99.4 0.0 X-RAY
 2021-06-23 ASP A:211 A:375 30.0 0.2 H -48.7 -53.6 17.0 0.113 0.087 C:None:0.087
 HOH
 9.054
 N
 O
7cdd 1 O60341 99.4 0.0 X-RAY
 2021-06-23 ASP A:211 A:375 35.0 0.233 H -47.0 -56.7 25.0 0.167 0.066 C:None:0.067
 HOH
 7.551
 OD2
 O
7cde 1 O60341 99.4 0.0 X-RAY
 2021-06-23 ASP A:211 A:375 32.0 0.213 H -47.4 -53.4 25.0 0.167 0.046 C:None:0.047
 GOL
 9.789
 N
 C3
7cdf 1 O60341 99.4 0.0 X-RAY
 2021-06-23 ASP A:211 A:375 36.0 0.24 H -49.7 -53.0 24.0 0.16 0.08 C:None:0.08
 GOL
HOH
 9.779
8.408
 N
OD2
 C3
O
7cdg 1 O60341 99.4 0.0 X-RAY
 2021-06-23 ASP A:211 A:375 37.0 0.247 H -45.3 -53.1 27.0 0.18 0.067 C:None:0.067
 GOL
HOH
 9.734
9.384
 N
N
 C3
O
2ejr 1 O60341 99.4 0.0 X-RAY
 2008-01-01 ASP A:204 A:375 27.0 0.18 H -51.1 -57.5 27.0 0.18 0.0 HOH
 2.625
 OD1
 O
2z3y 1 O60341 99.4 0.0 X-RAY
 2008-01-01 ASP A:204 A:375 30.0 0.2 H -51.7 -53.2 30.0 0.2 0.0 HOH
 2.400
 OD2
 O
2z5u 1 O60341 99.4 0.0 X-RAY
 2008-04-01 ASP A:204 A:375 29.0 0.193 H -54.2 -52.6 29.0 0.193 0.0 HOH
 7.611
 OD1
 O
3abt 1 O60341 99.4 0.0 X-RAY
 2010-07-07 ASP A:204 A:375 23.0 0.153 H -46.2 -35.1 23.0 0.153 0.0
3abu 1 O60341 99.4 0.0 X-RAY
 2010-07-07 ASP A:204 A:375 27.0 0.18 H -44.0 -50.1 27.0 0.18 0.0
6k3e 1 O60341 99.4 0.0 X-RAY
 2020-05-20 ASP A:204 A:375 27.0 0.18 H -35.1 -49.9 27.0 0.18 0.0 CW0
MLA
 8.075
9.506
 OD1
N
 C26
O1B
2dw4 1 O60341 99.4 0.0 X-RAY
 2007-09-04 ASP A:204 A:375 28.0 0.187 H -48.8 -55.9 28.0 0.187 0.0 HOH
 2.520
 OD2
 O
6w4k 1 O60341 99.4 0.0 X-RAY
 2020-10-21 ASP A:202 A:375 27.0 0.18 H -39.9 -44.3 27.0 0.18 0.0
6nqm 1 O60341 99.4 0.0 X-RAY
 2019-02-13 ASP A:203 A:375 25.0 0.167 H -51.3 -51.0 25.0 0.167 0.0
6nqu 1 O60341 99.4 0.0 X-RAY
 2019-02-13 ASP A:203 A:375 16.0 0.107 H -54.1 -50.3 16.0 0.107 0.0
6nr5 1 O60341 99.4 0.0 X-RAY
 2019-07-17 ASP A:203 A:375 29.0 0.193 H -54.0 -55.8 29.0 0.193 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 ASP A:375 A:375 36.0 0.24 H -62.4 -54.3