Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23395053 . A C CCDS30627.1:NM_015013.3:c.1129Atg>Ctg_NP_055828.2:p.377M>L Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
 2013-06-12 MET A:397 A:377 76.0 0.411 H -67.9 -50.9 76.0 0.411 0.0
3zmv 1 O60341 99.54 0.0 X-RAY
 2013-06-12 MET A:397 A:377 131.0 0.708 H -76.2 -37.3 131.0 0.708 0.0
3zms 1 O60341 99.43 0.0 X-RAY
 2013-06-12 MET A:397 A:377 80.0 0.432 H -75.3 -33.4 80.0 0.432 0.0
3zmt 1 O60341 99.43 0.0 X-RAY
 2013-06-12 MET A:397 A:377 113.0 0.611 H -93.3 -3.8 113.0 0.611 0.0
3zmz 1 O60341 99.43 0.0 X-RAY
 2013-06-12 MET A:397 A:377 131.0 0.708 H -72.7 -23.7 131.0 0.708 0.0
3zn0 1 O60341 99.43 0.0 X-RAY
 2013-06-12 MET A:397 A:377 116.0 0.627 H -84.1 -28.9 116.0 0.627 0.0
3zn1 1 O60341 99.43 0.0 X-RAY
 2013-06-12 MET A:397 A:377 121.0 0.654 H -112.0 7.8 121.0 0.654 0.0
4czz 1 O60341 99.43 0.0 X-RAY
 2014-06-11 MET A:397 A:377 110.0 0.595 H -51.5 -47.1 110.0 0.595 0.0
4uv8 1 O60341 99.43 0.0 X-RAY
 2014-09-10 MET A:397 A:377 114.0 0.616 H -58.5 -43.5 114.0 0.616 0.0
4uv9 1 O60341 99.43 0.0 X-RAY
 2014-09-10 MET A:397 A:377 122.0 0.659 H -73.6 -21.8 122.0 0.659 0.0
4uva 1 O60341 99.43 0.0 X-RAY
 2014-09-10 MET A:397 A:377 106.0 0.573 H -62.2 -37.7 106.0 0.573 0.0
4uvb 1 O60341 99.43 0.0 X-RAY
 2014-09-10 MET A:397 A:377 104.0 0.562 H -65.3 -42.3 104.0 0.562 0.0
4uvc 1 O60341 99.43 0.0 X-RAY
 2014-09-10 MET A:397 A:377 112.0 0.605 H -61.8 -33.3 112.0 0.605 0.0
6tuy 1 O60341 94.98 0.0 X-RAY
 2021-07-21 MET A:377 A:377 115.0 0.622 H -53.1 -49.7 115.0 0.622 0.0 HOH
 9.676
 N
 O
2xaf 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:377 A:377 69.0 0.373 H -64.1 -37.5 69.0 0.373 0.0
2xag 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:377 A:377 151.0 0.816 H -78.4 -36.1 151.0 0.816 0.0
2xah 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:377 A:377 64.0 0.346 H -65.7 -40.7 64.0 0.346 0.0
2xaj 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:377 A:377 107.0 0.578 H -58.6 -36.1 107.0 0.578 0.0
2xaq 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:377 A:377 73.0 0.395 H -42.1 -53.1 73.0 0.395 0.0
2xas 1 O60341 94.98 0.0 X-RAY
 2010-05-05 MET A:377 A:377 80.0 0.432 H -54.5 -56.2 80.0 0.432 0.0
4uxn 1 O60341 94.98 0.0 X-RAY
 2015-02-25 MET A:377 A:377 137.0 0.741 H -59.3 -52.5 137.0 0.741 0.0
5lhg 1 O60341 94.98 0.0 X-RAY
 2017-02-22 MET A:377 A:377 132.0 0.714 H -69.5 -5.5 132.0 0.714 0.0 6X3
 9.085
 N
 C34
5lhh 1 O60341 94.98 0.0 X-RAY
 2017-02-22 MET A:377 A:377 82.0 0.443 H -63.9 -30.8 82.0 0.443 0.0 HOH
 3.681
 CE
 O
5lhi 1 O60341 94.98 0.0 X-RAY
 2017-02-22 MET A:377 A:377 84.0 0.454 H -51.1 -56.4 84.0 0.454 0.0
6te1 1 O60341 94.98 0.0 X-RAY
 2020-06-03 MET A:377 A:377 125.0 0.676 H -68.2 -32.7 125.0 0.676 0.0
5l3c 1 O60341 94.86 0.0 X-RAY
 2016-05-04 MET A:377 A:377 73.0 0.395 H -61.8 -53.9 73.0 0.395 0.0
5l3d 1 O60341 94.86 0.0 X-RAY
 2016-05-04 MET A:377 A:377 72.0 0.389 H -57.4 -49.5 72.0 0.389 0.0
5l3b 1 O60341 94.86 0.0 X-RAY
 2016-05-04 MET A:377 A:377 71.0 0.384 H -63.5 -51.5 71.0 0.384 0.0
2x0l 1 O60341 100.0 0.0 X-RAY
 2010-03-02 MET A:259 A:377 139.0 0.751 H -81.5 -27.4 139.0 0.751 0.0
4bay 1 O60341 99.85 0.0 X-RAY
 2013-11-27 MET A:211 A:377 76.0 0.411 H -79.4 -34.3 76.0 0.411 0.0
2v1d 1 O60341 99.42 0.0 X-RAY
 2007-05-29 MET A:255 A:377 126.0 0.681 H -83.6 -23.1 126.0 0.681 0.0
2y48 1 O60341 99.42 0.0 X-RAY
 2011-02-16 MET A:255 A:377 122.0 0.659 H -94.7 -16.4 122.0 0.659 0.0
5l3e 1 O60341 99.42 0.0 X-RAY
 2016-09-21 MET A:255 A:377 119.0 0.643 H -69.7 -42.7 119.0 0.643 0.0 E11
 8.300
 O
 CBE
5l3f 1 O60341 99.42 0.0 X-RAY
 2016-09-21 MET A:255 A:377 120.0 0.649 H -65.4 -49.3 120.0 0.649 0.0
5l3g 1 O60341 99.42 0.0 X-RAY
 2016-09-21 MET A:255 A:377 125.0 0.676 H -62.4 -39.3 125.0 0.676 0.0
5lbq 1 O60341 99.42 0.0 X-RAY
 2016-09-21 MET A:255 A:377 79.0 0.427 H -61.5 -42.9 79.0 0.427 0.0
5lgt 1 O60341 99.42 0.0 X-RAY
 2017-02-22 MET A:255 A:377 132.0 0.714 H -52.1 -43.6 132.0 0.714 0.0
5lgu 1 O60341 99.42 0.0 X-RAY
 2017-02-22 MET A:255 A:377 65.0 0.351 H -72.2 -43.8 65.0 0.351 0.0
6vyp 7 O60341 98.69 0.0 X-RAY
 2020-05-27 MET S:209 M:377 113.0 0.611 H -69.2 -39.9 113.0 0.611 0.0
MET U:209 m:377 112.0 0.605 H -69.7 -39.7 NA NA NA
MET W:209 K:377 113.0 0.611 H -81.0 -33.7 113.0 0.611 0.0
MET Y:209 k:377 97.0 0.524 S -131.9 -25.2 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
 2017-02-22 MET A:211 A:381 73.0 0.395 H -65.0 -43.6 73.0 0.395 0.0
2iw5 1 O60341 99.4 0.0 X-RAY
 2006-08-09 MET A:207 A:377 119.0 0.643 H -57.2 -47.4 119.0 0.643 0.0 NH4
 9.892
 N
 N
2uxn 1 O60341 99.4 0.0 X-RAY
 2007-05-29 MET A:207 A:377 85.0 0.459 H -61.5 -48.3 85.0 0.459 0.0
2uxx 1 O60341 99.4 0.0 X-RAY
 2007-08-21 MET A:207 A:377 113.0 0.611 H -65.8 -41.8 113.0 0.611 0.0
4kum 1 O60341 99.4 0.0 X-RAY
 2014-05-07 MET A:207 A:377 95.0 0.514 H -56.3 -48.6 95.0 0.514 0.0 HOH
 8.573
 CE
 O
4xbf 1 O60341 99.4 0.0 X-RAY
 2016-04-27 MET A:207 A:377 96.0 0.519 H -63.0 -44.0 96.0 0.519 0.0 SO4
 5.828
 HE1
 O1
6wc6 1 O60341 99.4 0.0 X-RAY
 2021-06-30 MET A:207 A:377 92.0 0.497 H -50.7 -55.1 92.0 0.497 0.0
2h94 1 O60341 99.4 0.0 X-RAY
 2006-07-04 MET A:206 A:377 81.0 0.438 H -61.6 -53.5 81.0 0.438 0.0 HOH
 9.262
 O
 O
2hko 1 O60341 99.25 0.0 X-RAY
 2006-08-29 MET A:206 A:377 54.0 0.292 H -71.0 -51.2 54.0 0.292 0.0 HOH
 9.123
 N
 O
7e0g 1 O60341 99.1 0.0 X-RAY
 2021-03-24 MET A:209 A:377 69.0 0.373 H -65.4 -50.8 69.0 0.373 0.0 IMD
MG
HOH
 8.128
9.349
6.068
 N
CE
N
 N3
MG
O
6s35 1 O60341 99.4 0.0 X-RAY
 2020-02-26 MET A:210 A:377 74.0 0.4 H -57.9 -39.6 74.0 0.4 0.0
5h6q 1 O60341 99.4 0.0 X-RAY
 2017-04-12 MET A:213 A:377 64.0 0.346 H -76.4 -41.9 64.0 0.346 0.0 GOL
HOH
 6.659
4.466
 CE
SD
 O2
O
5h6r 1 O60341 99.4 0.0 X-RAY
 2017-04-12 MET A:213 A:377 73.0 0.395 H -70.8 -43.8 73.0 0.395 0.0
5x60 1 O60341 99.4 0.0 X-RAY
 2017-04-12 MET A:213 A:377 64.0 0.346 H -68.4 -44.2 64.0 0.346 0.0 HOH
 4.751
 SD
 O
5yjb 1 O60341 99.4 0.0 X-RAY
 2018-07-04 MET A:213 A:377 71.0 0.384 H -50.3 -35.9 71.0 0.384 0.0
6kgk 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:213 A:377 73.0 0.395 H -54.0 -40.6 73.0 0.395 0.0
6kgl 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:213 A:377 72.0 0.389 H -54.2 -40.1 72.0 0.389 0.0
6kgm 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:213 A:377 76.0 0.411 H -54.6 -46.5 76.0 0.411 0.0 GOL
 6.292
 CE
 O3
6kgn 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:213 A:377 76.0 0.411 H -54.7 -46.7 76.0 0.411 0.0 GOL
 6.297
 CE
 O3
6kgo 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:213 A:377 73.0 0.395 H -57.2 -48.5 73.0 0.395 0.0 GOL
HOH
 7.918
2.960
 N
O
 O2
O
6kgp 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:213 A:377 72.0 0.389 H -57.2 -47.9 72.0 0.389 0.0 GOL
HOH
 7.917
2.952
 N
O
 O2
O
6kgq 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:213 A:377 76.0 0.411 H -50.5 -52.1 76.0 0.411 0.0 HOH
 2.941
 O
 O
6kgr 1 O60341 99.4 0.0 X-RAY
 2020-03-25 MET A:213 A:377 76.0 0.411 H -50.7 -52.1 76.0 0.411 0.0 HOH
 2.935
 O
 O
7cdc 1 O60341 99.4 0.0 X-RAY
 2021-06-23 MET A:213 A:377 61.0 0.33 H -68.3 -46.7 61.0 0.33 0.0 HOH
 4.668
 SD
 O
7cdd 1 O60341 99.4 0.0 X-RAY
 2021-06-23 MET A:213 A:377 67.0 0.362 H -71.2 -44.4 67.0 0.362 0.0 HOH
 4.704
 SD
 O
7cde 1 O60341 99.4 0.0 X-RAY
 2021-06-23 MET A:213 A:377 69.0 0.373 H -70.5 -45.7 69.0 0.373 0.0 GOL
HOH
 7.013
4.527
 CE
SD
 O3
O
7cdf 1 O60341 99.4 0.0 X-RAY
 2021-06-23 MET A:213 A:377 66.0 0.357 H -68.6 -46.1 66.0 0.357 0.0 GOL
HOH
 7.373
4.669
 CE
SD
 O2
O
7cdg 1 O60341 99.4 0.0 X-RAY
 2021-06-23 MET A:213 A:377 65.0 0.351 H -66.3 -46.9 65.0 0.351 0.0 GOL
HOH
 7.257
4.245
 CE
SD
 O2
O
2ejr 1 O60341 99.4 0.0 X-RAY
 2008-01-01 MET A:206 A:377 73.0 0.395 H -60.2 -51.5 73.0 0.395 0.0 HOH
 3.126
 O
 O
2z3y 1 O60341 99.4 0.0 X-RAY
 2008-01-01 MET A:206 A:377 75.0 0.405 H -60.1 -54.7 75.0 0.405 0.0 HOH
 3.017
 O
 O
2z5u 1 O60341 99.4 0.0 X-RAY
 2008-04-01 MET A:206 A:377 72.0 0.389 H -60.8 -52.2 72.0 0.389 0.0 HOH
 2.914
 O
 O
3abt 1 O60341 99.4 0.0 X-RAY
 2010-07-07 MET A:206 A:377 69.0 0.373 H -58.1 -48.6 69.0 0.373 0.0
3abu 1 O60341 99.4 0.0 X-RAY
 2010-07-07 MET A:206 A:377 73.0 0.395 H -62.2 -61.8 73.0 0.395 0.0
6k3e 1 O60341 99.4 0.0 X-RAY
 2020-05-20 MET A:206 A:377 115.0 0.622 H -87.0 -8.1 115.0 0.622 0.0 MLA
 9.643
 CB
 O1A
2dw4 1 O60341 99.4 0.0 X-RAY
 2007-09-04 MET A:206 A:377 67.0 0.362 H -58.6 -57.1 67.0 0.362 0.0 HOH
 2.794
 O
 O
6w4k 1 O60341 99.4 0.0 X-RAY
 2020-10-21 MET A:204 A:377 72.0 0.389 H -45.2 -54.0 72.0 0.389 0.0
6nqm 1 O60341 99.4 0.0 X-RAY
 2019-02-13 MET A:205 A:377 90.0 NA H -61.9 -49.5 90.0 NA NA
6nqu 1 O60341 99.4 0.0 X-RAY
 2019-02-13 MET A:205 A:377 82.0 NA H -59.3 -48.6 82.0 NA NA
6nr5 1 O60341 99.4 0.0 X-RAY
 2019-07-17 MET A:205 A:377 85.0 NA H -58.9 -51.6 85.0 NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 MET A:377 A:377 76.0 0.411 H -64.9 -44.6