Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23395060 . A C CCDS30627.1:NM_015013.3:c.1136gAg>gCg_NP_055828.2:p.379E>A Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
 2013-06-12 GLU A:399 A:379 89.0 0.468 H -55.4 -48.5 89.0 0.468 0.0
3zmv 1 O60341 99.54 0.0 X-RAY
 2013-06-12 GLU A:399 A:379 88.0 0.463 H -60.4 -40.4 88.0 0.463 0.0
3zms 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLU A:399 A:379 93.0 0.489 H -54.3 -49.2 52.0 0.274 0.215 C:Q01101:0.216
3zmt 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLU A:399 A:379 91.0 0.479 H -56.8 -46.3 91.0 0.479 0.0
3zmz 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLU A:399 A:379 87.0 0.458 H -56.0 -47.5 87.0 0.458 0.0
3zn0 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLU A:399 A:379 90.0 0.474 H -55.8 -47.8 90.0 0.474 0.0
3zn1 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLU A:399 A:379 88.0 0.463 H -53.2 -44.1 88.0 0.463 0.0
4czz 1 O60341 99.43 0.0 X-RAY
 2014-06-11 GLU A:399 A:379 91.0 0.479 H -43.0 -59.8 91.0 0.479 0.0
4uv8 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLU A:399 A:379 90.0 0.474 H -57.4 -49.9 90.0 0.474 0.0
4uv9 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLU A:399 A:379 89.0 0.468 H -58.2 -46.6 89.0 0.468 0.0
4uva 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLU A:399 A:379 90.0 0.474 H -58.9 -47.7 90.0 0.474 0.0
4uvb 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLU A:399 A:379 90.0 0.474 H -56.4 -49.5 90.0 0.474 0.0
4uvc 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLU A:399 A:379 89.0 0.468 H -49.8 -54.0 89.0 0.468 0.0
6tuy 1 O60341 94.98 0.0 X-RAY
 2021-07-21 GLU A:379 A:379 97.0 0.511 H -43.5 -50.5 97.0 0.511 0.0 NY8
NY8
NY8
HOH
 6.882
6.824
8.569
3.083
 O
OE2
OE2
OE1
 CAB
CAR
CAA
O
2xaf 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLU A:379 A:379 91.0 0.479 H -40.8 -58.1 91.0 0.479 0.0
2xag 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLU A:379 A:379 93.0 0.489 H -47.0 -62.1 93.0 0.489 0.0
2xah 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLU A:379 A:379 88.0 0.463 H -45.3 -53.7 88.0 0.463 0.0
2xaj 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLU A:379 A:379 91.0 0.479 H -44.9 -57.8 91.0 0.479 0.0
2xaq 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLU A:379 A:379 91.0 0.479 H -58.0 -55.8 91.0 0.479 0.0
2xas 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLU A:379 A:379 91.0 0.479 H -49.5 -57.5 91.0 0.479 0.0
4uxn 1 O60341 94.98 0.0 X-RAY
 2015-02-25 GLU A:379 A:379 91.0 0.479 H -51.2 -48.0 91.0 0.479 0.0
5lhg 1 O60341 94.98 0.0 X-RAY
 2017-02-22 GLU A:379 A:379 87.0 0.458 H -63.7 -37.4 87.0 0.458 0.0 6X3
6X3
 2.886
8.241
 OE1
OE2
 N31
O27
5lhh 1 O60341 94.98 0.0 X-RAY
 2017-02-22 GLU A:379 A:379 86.0 0.453 H -57.6 -43.7 86.0 0.453 0.0 HOH
 9.643
 N
 O
5lhi 1 O60341 94.98 0.0 X-RAY
 2017-02-22 GLU A:379 A:379 100.0 0.526 H -69.9 -49.6 100.0 0.526 0.0 6X5
 8.552
 OE2
 C02
6te1 1 O60341 94.98 0.0 X-RAY
 2020-06-03 GLU A:379 A:379 85.0 0.447 H -63.9 -44.6 85.0 0.447 0.0 N4K
 3.197
 OE2
 C09
5l3c 1 O60341 94.86 0.0 X-RAY
 2016-05-04 LYS A:379 A:379 103.0 0.515 H -43.7 -61.6 103.0 0.515 0.0
5l3d 1 O60341 94.86 0.0 X-RAY
 2016-05-04 GLU A:379 A:379 92.0 0.484 H -56.8 -45.0 92.0 0.484 0.0 HOH
 8.728
 O
 O
5l3b 1 O60341 94.86 0.0 X-RAY
 2016-05-04 GLU A:379 A:379 89.0 0.468 H -50.1 -50.7 89.0 0.468 0.0
2x0l 1 O60341 100.0 0.0 X-RAY
 2010-03-02 GLU A:261 A:379 87.0 0.458 H -52.5 -59.3 39.0 0.205 0.253 C:Q5TEC6:0.253
4bay 1 O60341 99.85 0.0 X-RAY
 2013-11-27 GLU A:213 A:379 91.0 0.479 H -54.9 -45.0 91.0 0.479 0.0
2v1d 1 O60341 99.42 0.0 X-RAY
 2007-05-29 GLU A:257 A:379 89.0 0.468 H -50.3 -49.7 43.0 0.226 0.242 C:Q16695:0.242
2y48 1 O60341 99.42 0.0 X-RAY
 2011-02-16 GLU A:257 A:379 92.0 0.484 H -46.8 -60.1 40.0 0.211 0.273 C:O95863:0.274
5l3e 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLU A:257 A:379 88.0 0.463 H -52.9 -52.9 88.0 0.463 0.0 E11
E11
E11
 7.504
5.845
5.929
 O
O
OE2
 CBJ
CBE
CAX
5l3f 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLU A:257 A:379 94.0 0.495 H -42.9 -52.7 77.0 0.405 0.09 C:None:0.089
5l3g 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLU A:257 A:379 91.0 0.479 H -47.1 -51.4 39.0 0.205 0.274 C:None:0.274
5lbq 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLU A:257 A:379 89.0 0.468 H -51.0 -52.7 89.0 0.468 0.0 767
767
767
 7.041
7.300
7.276
 OE2
OE2
OE2
 C24
C24
C8
5lgt 1 O60341 99.42 0.0 X-RAY
 2017-02-22 GLU A:257 A:379 92.0 0.484 H -50.5 -51.3 92.0 0.484 0.0
5lgu 1 O60341 99.42 0.0 X-RAY
 2017-02-22 GLU A:257 A:379 89.0 0.468 H -46.3 -56.0 89.0 0.468 0.0
6vyp 7 O60341 98.69 0.0 X-RAY
 2020-05-27 GLU S:211 M:379 86.0 0.453 H -64.5 -37.3 43.0 0.226 0.227 E:A0A310TTQ1:0.226
 DG
DC
DT
 9.160
8.188
9.117
 OE1
O
OE2
 O5'
OP1
OP1
GLU U:211 m:379 86.0 0.453 H -64.8 -36.9 NA NA NA
GLU W:211 K:379 93.0 0.489 H -66.6 -35.7 52.0 0.274 0.215 A:A0A310TTQ1:0.216
 DC
DA
DA
 9.127
8.509
9.788
 OE2
OE1
OE2
 OP1
OP1
OP1
GLU Y:211 k:379 113.0 0.595 H -70.9 -35.0 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
 2017-02-22 GLU A:213 A:383 99.0 0.521 H -45.6 -52.8 99.0 0.521 0.0
2iw5 1 O60341 99.4 0.0 X-RAY
 2006-08-09 GLU A:209 A:379 96.0 0.505 H -65.7 -38.6 96.0 0.505 0.0 GOL
NH4
HOH
 6.167
4.592
4.095
 OE2
CD
OE2
 O1
N
O
2uxn 1 O60341 99.4 0.0 X-RAY
 2007-05-29 GLU A:209 A:379 91.0 0.479 H -58.7 -44.7 89.0 0.468 0.011 C:P68431:0.011
 HOH
 4.371
 OE2
 O
2uxx 1 O60341 99.4 0.0 X-RAY
 2007-08-21 GLU A:209 A:379 90.0 0.474 H -62.9 -42.3 90.0 0.474 0.0 GOL
 6.904
 OE2
 O2
4kum 1 O60341 99.4 0.0 X-RAY
 2014-05-07 GLU A:209 A:379 85.0 0.447 H -63.3 -41.3 85.0 0.447 0.0 THG
HOH
 9.631
9.234
 OE1
OE1
 OE2
O
4xbf 1 O60341 99.4 0.0 X-RAY
 2016-04-27 GLU A:209 A:379 90.0 0.474 H -63.1 -29.7 90.0 0.474 0.0
6wc6 1 O60341 99.4 0.0 X-RAY
 2021-06-30 GLU A:209 A:379 89.0 0.468 H -65.6 -44.3 89.0 0.468 0.0
2h94 1 O60341 99.4 0.0 X-RAY
 2006-07-04 GLU A:208 A:379 81.0 0.426 H -53.1 -37.3 81.0 0.426 0.0 HG
HOH
 6.159
3.472
 OE2
OE1
 HG
O
2hko 1 O60341 99.25 0.0 X-RAY
 2006-08-29 GLU A:208 A:379 96.0 0.505 H -48.1 -35.2 96.0 0.505 0.0 HOH
 3.692
 OE1
 O
7e0g 1 O60341 99.1 0.0 X-RAY
 2021-03-24 GLU A:211 A:379 74.0 0.389 H -59.8 -42.8 74.0 0.389 0.0 IMD
MG
HOH
 2.885
9.776
3.166
 OE1
O
OE2
 C2
MG
O
6s35 1 O60341 99.4 0.0 X-RAY
 2020-02-26 GLU A:212 A:379 85.0 0.447 H -49.5 -61.2 6.0 0.032 0.415 C:None:0.416
5h6q 1 O60341 99.4 0.0 X-RAY
 2017-04-12 GLU A:215 A:379 91.0 0.479 H -57.6 -45.0 41.0 0.216 0.263 C:None:0.263
 HOH
 9.858
 N
 O
5h6r 1 O60341 99.4 0.0 X-RAY
 2017-04-12 GLU A:215 A:379 90.0 0.474 H -60.7 -42.3 43.0 0.226 0.248 C:None:0.247
5x60 1 O60341 99.4 0.0 X-RAY
 2017-04-12 GLU A:215 A:379 89.0 0.468 H -58.7 -41.1 44.0 0.232 0.236 C:None:0.237
 HOH
 9.817
 N
 O
5yjb 1 O60341 99.4 0.0 X-RAY
 2018-07-04 GLU A:215 A:379 89.0 0.468 H -54.7 -46.0 89.0 0.468 0.0
6kgk 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLU A:215 A:379 90.0 0.474 H -56.5 -43.5 90.0 0.474 0.0 GOL
 8.359
 OE2
 O1
6kgl 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLU A:215 A:379 91.0 0.479 H -56.8 -42.9 91.0 0.479 0.0 GOL
 8.340
 OE2
 O1
6kgm 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLU A:215 A:379 89.0 0.468 H -60.3 -42.9 89.0 0.468 0.0 GOL
HOH
 8.232
9.447
 OE2
OE2
 O1
O
6kgn 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLU A:215 A:379 90.0 0.474 H -60.3 -42.7 90.0 0.474 0.0 GOL
HOH
 8.232
9.476
 OE2
OE2
 O1
O
6kgo 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLU A:215 A:379 86.0 0.453 H -58.5 -44.5 86.0 0.453 0.0 GOL
GOL
HOH
 6.532
3.133
3.054
 OE2
OE1
OE2
 O3
O2
O
6kgp 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLU A:215 A:379 88.0 0.463 H -58.9 -44.8 88.0 0.463 0.0 GOL
GOL
HOH
 6.563
3.152
3.040
 OE2
OE1
OE2
 O3
O2
O
6kgq 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLU A:215 A:379 82.0 0.432 H -63.4 -34.6 82.0 0.432 0.0 MPD
HOH
 7.807
6.098
 OE2
C
 C5
O
6kgr 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLU A:215 A:379 82.0 0.432 H -63.4 -34.9 82.0 0.432 0.0 MPD
HOH
 7.816
6.102
 OE2
C
 C5
O
7cdc 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLU A:215 A:379 97.0 0.511 H -53.4 -49.1 42.0 0.221 0.29 C:None:0.289
 HOH
 5.692
 CG
 O
7cdd 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLU A:215 A:379 94.0 0.495 H -49.4 -46.6 50.0 0.263 0.232 C:None:0.232
 HOH
 3.458
 OE2
 O
7cde 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLU A:215 A:379 95.0 0.5 H -52.5 -52.6 20.0 0.105 0.395 C:None:0.395
7cdf 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLU A:215 A:379 96.0 0.505 H -56.8 -47.3 49.0 0.258 0.247 C:None:0.247
 HOH
 3.706
 OE2
 O
7cdg 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLU A:215 A:379 96.0 0.505 H -55.1 -47.3 18.0 0.095 0.41 C:None:0.411
 HOH
 9.939
 N
 O
2ejr 1 O60341 99.4 0.0 X-RAY
 2008-01-01 GLU A:208 A:379 84.0 0.442 H -61.2 -32.6 84.0 0.442 0.0 HOH
 3.903
 N
 O
2z3y 1 O60341 99.4 0.0 X-RAY
 2008-01-01 GLU A:208 A:379 89.0 0.468 H -63.2 -32.3 89.0 0.468 0.0 HOH
 4.313
 CG
 O
2z5u 1 O60341 99.4 0.0 X-RAY
 2008-04-01 GLU A:208 A:379 90.0 0.474 H -66.3 -30.9 90.0 0.474 0.0 HOH
 4.306
 CG
 O
3abt 1 O60341 99.4 0.0 X-RAY
 2010-07-07 GLU A:208 A:379 88.0 0.463 H -55.8 -31.2 88.0 0.463 0.0
3abu 1 O60341 99.4 0.0 X-RAY
 2010-07-07 GLU A:208 A:379 82.0 0.432 H -66.6 -41.4 82.0 0.432 0.0
6k3e 1 O60341 99.4 0.0 X-RAY
 2020-05-20 GLU A:208 A:379 91.0 0.479 H -51.6 -45.6 91.0 0.479 0.0 CW0
PEG
 5.551
9.918
 OE1
OE2
 C26
C2
2dw4 1 O60341 99.4 0.0 X-RAY
 2007-09-04 GLU A:208 A:379 86.0 0.453 H -58.5 -39.2 86.0 0.453 0.0 HOH
 3.575
 OE2
 O
6w4k 1 O60341 99.4 0.0 X-RAY
 2020-10-21 GLU A:206 A:379 97.0 0.511 H -48.6 -46.6 97.0 0.511 0.0
6nqm 1 O60341 99.4 0.0 X-RAY
 2019-02-13 GLU A:207 A:379 93.0 0.489 H -64.0 -44.4 93.0 0.489 0.0
6nqu 1 O60341 99.4 0.0 X-RAY
 2019-02-13 GLU A:207 A:379 88.0 0.463 H -65.1 -44.0 88.0 0.463 0.0
6nr5 1 O60341 99.4 0.0 X-RAY
 2019-07-17 GLU A:207 A:379 81.0 0.426 H -62.3 -47.0 81.0 0.426 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 GLU A:379 A:379 41.0 0.216 H -62.3 -41.9