Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 23397787 | . | C | A | CCDS30627.1:NM_015013.3:c.1411Ccc>Acc_NP_055828.2:p.471P>T | Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3zmu | 1 | O60341 | 99.54 | 0.0 |
X-RAY |
2013-06-12 | PRO | A:491 | A:471 | 134.0 | 0.924 | S | -80.1 | 144.7 | 134.0 | 0.924 | 0.0 | ||||||
| 3zmv | 1 | O60341 | 99.54 | 0.0 |
X-RAY |
2013-06-12 | PRO | A:491 | A:471 | 133.0 | 0.917 | S | -81.4 | 146.9 | 133.0 | 0.917 | 0.0 | ||||||
| 3zms | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | PRO | A:491 | A:471 | 136.0 | 0.938 | S | -82.6 | 142.4 | 136.0 | 0.938 | 0.0 | ||||||
| 3zmt | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | PRO | A:491 | A:471 | 138.0 | 0.952 | S | -82.9 | 138.9 | 138.0 | 0.952 | 0.0 | ||||||
| 3zmz | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | PRO | A:491 | A:471 | 134.0 | 0.924 | S | -82.0 | 140.2 | 134.0 | 0.924 | 0.0 | ||||||
| 3zn0 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | PRO | A:491 | A:471 | 137.0 | 0.945 | S | -74.5 | 136.1 | 137.0 | 0.945 | 0.0 | ||||||
| 3zn1 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | PRO | A:491 | A:471 | 134.0 | 0.924 | S | -80.1 | 145.4 | 134.0 | 0.924 | 0.0 | ||||||
| 4czz | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-06-11 | PRO | A:491 | A:471 | 134.0 | 0.924 | S | -83.4 | 132.0 | 134.0 | 0.924 | 0.0 | ||||||
| 4uv8 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | PRO | A:491 | A:471 | 135.0 | 0.931 | S | -81.9 | 142.3 | 135.0 | 0.931 | 0.0 | ||||||
| 4uv9 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | PRO | A:491 | A:471 | 133.0 | 0.917 | S | -85.6 | 130.1 | 133.0 | 0.917 | 0.0 | ||||||
| 4uva | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | PRO | A:491 | A:471 | 135.0 | 0.931 | S | -82.3 | 137.2 | 135.0 | 0.931 | 0.0 | ||||||
| 4uvb | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | PRO | A:491 | A:471 | 134.0 | 0.924 | S | -81.0 | 144.5 | 134.0 | 0.924 | 0.0 | ||||||
| 4uvc | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | PRO | A:491 | A:471 | 136.0 | 0.938 | S | -81.5 | 129.0 | 136.0 | 0.938 | 0.0 | ||||||
| 6tuy | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2021-07-21 | PRO | A:471 | A:471 | 134.0 | 0.924 | S | -68.2 | 150.3 | 134.0 | 0.924 | 0.0 |
PO4 CL |
3.557 3.927 |
O CA |
O3 CL |
||
| 2xaf | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | PRO | A:471 | A:471 | 133.0 | 0.917 | S | -82.4 | 151.0 | 133.0 | 0.917 | 0.0 | ||||||
| 2xag | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | PRO | A:471 | A:471 | 133.0 | 0.917 | S | -88.8 | 125.7 | 133.0 | 0.917 | 0.0 | ||||||
| 2xah | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | PRO | A:471 | A:471 | 134.0 | 0.924 | S | -78.5 | 142.2 | 134.0 | 0.924 | 0.0 | ||||||
| 2xaj | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | PRO | A:471 | A:471 | 134.0 | 0.924 | S | -85.9 | 143.5 | 134.0 | 0.924 | 0.0 | ||||||
| 2xaq | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | PRO | A:471 | A:471 | 132.0 | 0.91 | S | -75.7 | 159.0 | 132.0 | 0.91 | 0.0 | ||||||
| 2xas | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | PRO | A:471 | A:471 | 136.0 | 0.938 | S | -82.2 | 129.2 | 136.0 | 0.938 | 0.0 | ||||||
| 4uxn | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2015-02-25 | PRO | A:471 | A:471 | 134.0 | 0.924 | S | -89.2 | 136.4 | 134.0 | 0.924 | 0.0 | ||||||
| 5lhg | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | PRO | A:471 | A:471 | 133.0 | 0.917 | S | -79.4 | 151.1 | 133.0 | 0.917 | 0.0 |
HOH |
2.296 |
O |
O |
||
| 5lhh | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | PRO | A:471 | A:471 | 135.0 | 0.931 | S | -77.6 | 150.6 | 135.0 | 0.931 | 0.0 | ||||||
| 5lhi | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | PRO | A:471 | A:471 | 130.0 | 0.897 | S | -75.8 | 161.8 | 130.0 | 0.897 | 0.0 | ||||||
| 6te1 | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2020-06-03 | PRO | A:471 | A:471 | 132.0 | 0.91 | S | -84.0 | 156.4 | 132.0 | 0.91 | 0.0 | ||||||
| 5l3c | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | PRO | A:471 | A:471 | 132.0 | 0.91 | S | -74.4 | 147.7 | 132.0 | 0.91 | 0.0 | ||||||
| 5l3d | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | PRO | A:471 | A:471 | 134.0 | 0.924 | S | -81.2 | 148.2 | 134.0 | 0.924 | 0.0 |
HOH |
5.368 |
O |
O |
||
| 5l3b | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | PRO | A:471 | A:471 | 135.0 | 0.931 | S | -69.4 | 151.4 | 135.0 | 0.931 | 0.0 | ||||||
| 2x0l | 1 | O60341 | 100.0 | 0.0 |
X-RAY |
2010-03-02 | PRO | A:353 | A:471 | 135.0 | 0.931 | S | -89.2 | 158.3 | 135.0 | 0.931 | 0.0 | ||||||
| 4bay | 1 | O60341 | 99.85 | 0.0 |
X-RAY |
2013-11-27 | PRO | A:305 | A:471 | 136.0 | 0.938 | S | -81.5 | 125.9 | 136.0 | 0.938 | 0.0 | ||||||
| 2v1d | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2007-05-29 | PRO | A:349 | A:471 | 128.0 | 0.883 | S | -90.7 | 167.7 | 128.0 | 0.883 | 0.0 | ||||||
| 2y48 | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2011-02-16 | PRO | A:349 | A:471 | 134.0 | 0.924 | S | -78.9 | 140.9 | 134.0 | 0.924 | 0.0 | ||||||
| 5l3e | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | PRO | A:349 | A:471 | 137.0 | 0.945 | S | -80.1 | 137.2 | 137.0 | 0.945 | 0.0 | ||||||
| 5l3f | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | PRO | A:349 | A:471 | 130.0 | 0.897 | S | -76.5 | 153.6 | 130.0 | 0.897 | 0.0 | ||||||
| 5l3g | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | PRO | A:349 | A:471 | 137.0 | 0.945 | S | -80.7 | 132.7 | 137.0 | 0.945 | 0.0 | ||||||
| 5lbq | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | PRO | A:349 | A:471 | 129.0 | 0.89 | S | -87.7 | 143.2 | 129.0 | 0.89 | 0.0 | ||||||
| 5lgt | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2017-02-22 | PRO | A:349 | A:471 | 130.0 | 0.897 | S | -76.2 | 153.1 | 130.0 | 0.897 | 0.0 | ||||||
| 5lgu | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2017-02-22 | PRO | A:349 | A:471 | 136.0 | 0.938 | S | -63.6 | 151.2 | 136.0 | 0.938 | 0.0 | ||||||
| 6vyp | 7 | O60341 | 98.69 | 0.0 |
X-RAY |
2020-05-27 | PRO | S:303 | M:471 | 120.0 | 0.828 | S | -77.4 | 71.2 | 120.0 | 0.828 | 0.0 | ||||||
| PRO | U:303 | m:471 | 114.0 | 0.786 | S | -78.9 | 73.0 | NA | NA | NA | |||||||||||||
| PRO | W:303 | K:471 | 116.0 | 0.8 | T | -77.1 | -8.0 | 116.0 | 0.8 | 0.0 | |||||||||||||
| PRO | Y:303 | k:471 | 135.0 | 0.931 | S | -81.1 | 131.0 | NA | NA | NA | |||||||||||||
| 5lgn | 1 | O60341 | 99.85 | 0.0 |
X-RAY |
2017-02-22 | PRO | A:305 | A:475 | 132.0 | 0.91 | S | -77.1 | 147.7 | 132.0 | 0.91 | 0.0 | ||||||
| 2iw5 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2006-08-09 | PRO | A:301 | A:471 | 138.0 | 0.952 | S | -70.2 | 135.6 | 138.0 | 0.952 | 0.0 | ||||||
| 2uxn | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-05-29 | PRO | A:301 | A:471 | 134.0 | 0.924 | S | -84.1 | 151.0 | 134.0 | 0.924 | 0.0 | ||||||
| 2uxx | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-08-21 | PRO | A:301 | A:471 | 132.0 | 0.91 | S | -73.3 | 151.3 | 132.0 | 0.91 | 0.0 | ||||||
| 4kum | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2014-05-07 | PRO | A:301 | A:471 | 132.0 | 0.91 | S | -65.4 | 160.0 | 132.0 | 0.91 | 0.0 | ||||||
| 4xbf | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2016-04-27 | PRO | A:301 | A:471 | 136.0 | 0.938 | S | -77.1 | 140.1 | 136.0 | 0.938 | 0.0 | ||||||
| 6wc6 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-30 | PRO | A:301 | A:471 | 136.0 | 0.938 | S | -80.7 | 136.9 | 136.0 | 0.938 | 0.0 | ||||||
| 2h94 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2006-07-04 | PRO | A:300 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2hko | 1 | O60341 | 99.25 | 0.0 |
X-RAY |
2006-08-29 | PRO | A:300 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 7e0g | 1 | O60341 | 99.1 | 0.0 |
X-RAY |
2021-03-24 | PRO | A:303 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6s35 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-02-26 | PRO | A:304 | A:471 | 140.0 | 0.966 | S | -77.6 | 116.4 | 140.0 | 0.966 | 0.0 | ||||||
| 5h6q | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | PRO | A:307 | A:471 | 134.0 | 0.924 | S | -74.8 | 149.4 | 134.0 | 0.924 | 0.0 | ||||||
| 5h6r | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | PRO | A:307 | A:471 | 135.0 | 0.931 | S | -85.8 | 140.8 | 135.0 | 0.931 | 0.0 | ||||||
| 5x60 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | PRO | A:307 | A:471 | 134.0 | 0.924 | S | -76.0 | 149.9 | 134.0 | 0.924 | 0.0 | ||||||
| 5yjb | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2018-07-04 | PRO | A:307 | A:471 | 137.0 | 0.945 | S | -75.9 | 130.1 | 137.0 | 0.945 | 0.0 | ||||||
| 6kgk | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | PRO | A:307 | A:471 | 136.0 | 0.938 | S | -77.1 | 138.1 | 136.0 | 0.938 | 0.0 |
HOH |
4.777 |
O |
O |
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| 6kgl | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | PRO | A:307 | A:471 | 136.0 | 0.938 | S | -77.9 | 138.9 | 136.0 | 0.938 | 0.0 |
HOH |
4.827 |
O |
O |
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| 6kgm | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | PRO | A:307 | A:471 | 132.0 | 0.91 | S | -83.7 | 147.5 | 132.0 | 0.91 | 0.0 |
HOH |
8.576 |
O |
O |
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| 6kgn | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | PRO | A:307 | A:471 | 133.0 | 0.917 | S | -83.8 | 148.2 | 133.0 | 0.917 | 0.0 |
HOH |
8.580 |
O |
O |
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| 6kgo | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | PRO | A:307 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6kgp | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | PRO | A:307 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6kgq | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | PRO | A:307 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6kgr | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | PRO | A:307 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 7cdc | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | PRO | A:307 | A:471 | 137.0 | 0.945 | S | -81.6 | 142.1 | 137.0 | 0.945 | 0.0 |
HOH |
9.851 |
C |
O |
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| 7cdd | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | PRO | A:307 | A:471 | 134.0 | 0.924 | S | -77.0 | 144.9 | 134.0 | 0.924 | 0.0 | ||||||
| 7cde | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | PRO | A:307 | A:471 | 136.0 | 0.938 | S | -79.5 | 145.4 | 136.0 | 0.938 | 0.0 | ||||||
| 7cdf | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | PRO | A:307 | A:471 | 134.0 | 0.924 | S | -78.7 | 145.1 | 134.0 | 0.924 | 0.0 |
HOH |
8.716 |
N |
O |
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| 7cdg | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | PRO | A:307 | A:471 | 135.0 | 0.931 | S | -78.0 | 151.7 | 135.0 | 0.931 | 0.0 | ||||||
| 2ejr | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-01-01 | PRO | A:300 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2z3y | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-01-01 | PRO | A:300 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2z5u | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-04-01 | PRO | A:300 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3abt | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2010-07-07 | PRO | A:300 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3abu | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2010-07-07 | PRO | A:300 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6k3e | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-05-20 | PRO | A:300 | A:471 | 138.0 | 0.952 | S | -73.2 | 147.7 | 138.0 | 0.952 | 0.0 |
HOH |
4.950 |
O |
O |
||
| 2dw4 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-09-04 | PRO | A:300 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6w4k | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-10-21 | PRO | A:298 | A:471 | 133.0 | 0.917 | S | -64.2 | 83.5 | 133.0 | 0.917 | 0.0 | ||||||
| 6nqm | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-02-13 | PRO | A:299 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6nqu | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-02-13 | PRO | A:299 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6nr5 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-07-17 | PRO | A:299 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o60341-f1 | 1 | O60341 | 94.98 | 0.0 | PRO | A:471 | A:471 | 135.0 | 0.931 | S | -72.2 | 135.2 | |