Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23399793 . A C CCDS30627.1:NM_015013.3:c.1559tAt>tCt_NP_055828.2:p.520Y>S Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
 2013-06-12 TYR A:540 A:520 32.0 0.139 S -77.1 -49.6 32.0 0.139 0.0
3zmv 1 O60341 99.54 0.0 X-RAY
 2013-06-12 TYR A:540 A:520 41.0 0.178 S -80.0 -52.8 41.0 0.178 0.0
3zms 1 O60341 99.43 0.0 X-RAY
 2013-06-12 TYR A:540 A:520 36.0 0.157 S -78.3 -51.8 36.0 0.157 0.0
3zmt 1 O60341 99.43 0.0 X-RAY
 2013-06-12 TYR A:540 A:520 38.0 0.165 S -76.5 -51.4 37.0 0.161 0.004 B:Q9UKL0:0.004
3zmz 1 O60341 99.43 0.0 X-RAY
 2013-06-12 TYR A:540 A:520 39.0 0.17 S -71.4 -55.1 39.0 0.17 0.0
3zn0 1 O60341 99.43 0.0 X-RAY
 2013-06-12 TYR A:540 A:520 37.0 0.161 S -77.3 -53.2 37.0 0.161 0.0
3zn1 1 O60341 99.43 0.0 X-RAY
 2013-06-12 TYR A:540 A:520 36.0 0.157 S -71.3 -53.7 36.0 0.157 0.0
4czz 1 O60341 99.43 0.0 X-RAY
 2014-06-11 TYR A:540 A:520 41.0 0.178 S -75.8 -54.1 41.0 0.178 0.0
4uv8 1 O60341 99.43 0.0 X-RAY
 2014-09-10 TYR A:540 A:520 39.0 0.17 S -74.9 -52.8 39.0 0.17 0.0 HOH
 3.535
 N
 O
4uv9 1 O60341 99.43 0.0 X-RAY
 2014-09-10 TYR A:540 A:520 37.0 0.161 S -71.6 -53.5 37.0 0.161 0.0
4uva 1 O60341 99.43 0.0 X-RAY
 2014-09-10 TYR A:540 A:520 38.0 0.165 S -74.2 -53.0 37.0 0.161 0.004 B:Q9UKL0:0.004
4uvb 1 O60341 99.43 0.0 X-RAY
 2014-09-10 TYR A:540 A:520 38.0 0.165 S -73.5 -52.6 37.0 0.161 0.004 B:Q9UKL0:0.004
4uvc 1 O60341 99.43 0.0 X-RAY
 2014-09-10 TYR A:540 A:520 36.0 0.157 S -71.0 -54.1 35.0 0.152 0.005 B:Q9UKL0:0.004
6tuy 1 O60341 94.98 0.0 X-RAY
 2021-07-21 TYR A:520 A:520 37.0 0.161 S -63.9 -56.0 37.0 0.161 0.0
2xaf 1 O60341 94.98 0.0 X-RAY
 2010-05-05 TYR A:520 A:520 37.0 0.161 S -67.2 -59.4 37.0 0.161 0.0
2xag 1 O60341 94.98 0.0 X-RAY
 2010-05-05 TYR A:520 A:520 42.0 0.183 S -69.7 -53.9 42.0 0.183 0.0
2xah 1 O60341 94.98 0.0 X-RAY
 2010-05-05 TYR A:520 A:520 35.0 0.152 S -63.5 -54.4 35.0 0.152 0.0
2xaj 1 O60341 94.98 0.0 X-RAY
 2010-05-05 TYR A:520 A:520 36.0 0.157 S -71.6 -61.9 36.0 0.157 0.0
2xaq 1 O60341 94.98 0.0 X-RAY
 2010-05-05 TYR A:520 A:520 36.0 0.157 S -77.7 -49.2 35.0 0.152 0.005 B:Q9UKL0:0.004
2xas 1 O60341 94.98 0.0 X-RAY
 2010-05-05 TYR A:520 A:520 28.0 0.122 S -74.0 -52.8 28.0 0.122 0.0
4uxn 1 O60341 94.98 0.0 X-RAY
 2015-02-25 TYR A:520 A:520 40.0 0.174 S -72.9 -53.0 40.0 0.174 0.0
5lhg 1 O60341 94.98 0.0 X-RAY
 2017-02-22 TYR A:520 A:520 38.0 0.165 S -79.7 -56.8 38.0 0.165 0.0 GOL
 9.584
 CE2
 O1
5lhh 1 O60341 94.98 0.0 X-RAY
 2017-02-22 TYR A:520 A:520 36.0 0.157 S -77.2 -57.4 36.0 0.157 0.0 GOL
HOH
 9.514
3.675
 CE2
O
 O3
O
5lhi 1 O60341 94.98 0.0 X-RAY
 2017-02-22 TYR A:520 A:520 32.0 0.139 S -59.9 -47.5 31.0 0.135 0.004 B:Q9UKL0:0.004
 GOL
 9.773
 CE2
 O1
6te1 1 O60341 94.98 0.0 X-RAY
 2020-06-03 TYR A:520 A:520 39.0 0.17 S -73.9 -56.0 39.0 0.17 0.0 GOL
 9.262
 CE2
 O1
5l3c 1 O60341 94.86 0.0 X-RAY
 2016-05-04 TYR A:520 A:520 38.0 0.165 S -73.0 -57.3 38.0 0.165 0.0
5l3d 1 O60341 94.86 0.0 X-RAY
 2016-05-04 TYR A:520 A:520 38.0 0.165 S -70.5 -52.6 38.0 0.165 0.0
5l3b 1 O60341 94.86 0.0 X-RAY
 2016-05-04 TYR A:520 A:520 41.0 0.178 S -78.5 -58.2 41.0 0.178 0.0
2x0l 1 O60341 100.0 0.0 X-RAY
 2010-03-02 TYR A:402 A:520 36.0 0.157 S -67.6 -52.8 36.0 0.157 0.0
4bay 1 O60341 99.85 0.0 X-RAY
 2013-11-27 TYR A:354 A:520 39.0 0.17 S -72.8 -54.5 39.0 0.17 0.0
2v1d 1 O60341 99.42 0.0 X-RAY
 2007-05-29 TYR A:398 A:520 35.0 0.152 S -73.8 -53.2 35.0 0.152 0.0
2y48 1 O60341 99.42 0.0 X-RAY
 2011-02-16 TYR A:398 A:520 39.0 0.17 S -69.9 -50.7 39.0 0.17 0.0
5l3e 1 O60341 99.42 0.0 X-RAY
 2016-09-21 TYR A:398 A:520 36.0 0.157 S -72.0 -54.2 36.0 0.157 0.0
5l3f 1 O60341 99.42 0.0 X-RAY
 2016-09-21 TYR A:398 A:520 35.0 0.152 S -91.7 -48.0 35.0 0.152 0.0
5l3g 1 O60341 99.42 0.0 X-RAY
 2016-09-21 TYR A:398 A:520 38.0 0.165 S -91.8 -45.8 38.0 0.165 0.0
5lbq 1 O60341 99.42 0.0 X-RAY
 2016-09-21 TYR A:398 A:520 31.0 0.135 S -63.5 -55.3 31.0 0.135 0.0
5lgt 1 O60341 99.42 0.0 X-RAY
 2017-02-22 TYR A:398 A:520 41.0 0.178 S -79.9 -54.1 41.0 0.178 0.0
5lgu 1 O60341 99.42 0.0 X-RAY
 2017-02-22 TYR A:398 A:520 37.0 0.161 S -81.2 -60.3 37.0 0.161 0.0
6vyp 7 O60341 98.69 0.0 X-RAY
 2020-05-27 TYR S:352 M:520 93.0 0.404 T 46.4 -115.4 93.0 0.404 0.0
TYR U:352 m:520 149.0 0.648 T 48.7 -110.1 NA NA NA
TYR W:352 K:520 128.0 0.557 -96.3 -147.6 128.0 0.557 0.0
TYR Y:352 k:520 159.0 0.691 T 56.1 43.4 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
 2017-02-22 TYR A:354 A:524 39.0 0.17 S -78.4 -58.1 39.0 0.17 0.0
2iw5 1 O60341 99.4 0.0 X-RAY
 2006-08-09 TYR A:350 A:520 40.0 0.174 S -80.0 -53.1 40.0 0.174 0.0 GOL
HOH
 8.775
2.998
 CE2
N
 O1
O
2uxn 1 O60341 99.4 0.0 X-RAY
 2007-05-29 TYR A:350 A:520 32.0 0.139 S -77.4 -46.1 32.0 0.139 0.0 GOL
HOH
 9.163
5.407
 CE2
CD2
 O3
O
2uxx 1 O60341 99.4 0.0 X-RAY
 2007-08-21 TYR A:350 A:520 42.0 0.183 S -79.8 -53.3 42.0 0.183 0.0 GOL
 9.130
 CE2
 O1
4kum 1 O60341 99.4 0.0 X-RAY
 2014-05-07 TYR A:350 A:520 40.0 0.174 S -80.9 -50.0 40.0 0.174 0.0 GOL
 9.137
 CE2
 O3
4xbf 1 O60341 99.4 0.0 X-RAY
 2016-04-27 TYR A:350 A:520 37.0 0.161 S -73.3 -42.4 37.0 0.161 0.0 SO4
GOL
 8.722
7.906
 O
HE2
 O2
HO1
6wc6 1 O60341 99.4 0.0 X-RAY
 2021-06-30 TYR A:350 A:520 37.0 0.161 S -78.4 -46.5 37.0 0.161 0.0
2h94 1 O60341 99.4 0.0 X-RAY
 2006-07-04 TYR A:349 A:520 32.0 0.139 S -59.8 -55.9 32.0 0.139 0.0 HG
HOH
 7.336
7.837
 OH
CD2
 HG
O
2hko 1 O60341 99.25 0.0 X-RAY
 2006-08-29 TYR A:349 A:520 33.0 0.143 S -90.6 -2.4 33.0 0.143 0.0
7e0g 1 O60341 99.1 0.0 X-RAY
 2021-03-24 TYR A:352 A:520 27.0 0.117 S -63.9 -50.1 27.0 0.117 0.0 GOL
MG
HOH
 8.727
4.832
4.898
 CE2
OH
N
 O1
MG
O
6s35 1 O60341 99.4 0.0 X-RAY
 2020-02-26 TYR A:353 A:520 39.0 0.17 S -76.1 -60.9 39.0 0.17 0.0
5h6q 1 O60341 99.4 0.0 X-RAY
 2017-04-12 TYR A:356 A:520 37.0 0.161 S -65.6 -55.4 37.0 0.161 0.0 GOL
GOL
HOH
 9.337
8.543
3.706
 CE2
O
O
 C3
O2
O
5h6r 1 O60341 99.4 0.0 X-RAY
 2017-04-12 TYR A:356 A:520 42.0 0.183 S -70.9 -49.9 42.0 0.183 0.0 GOL
HOH
 9.222
3.019
 CE2
N
 C3
O
5x60 1 O60341 99.4 0.0 X-RAY
 2017-04-12 TYR A:356 A:520 37.0 0.161 S -71.1 -55.0 37.0 0.161 0.0 GOL
HOH
 9.412
3.903
 CE2
O
 C3
O
5yjb 1 O60341 99.4 0.0 X-RAY
 2018-07-04 TYR A:356 A:520 34.0 0.148 S -68.0 -50.5 34.0 0.148 0.0 GOL
 9.529
 CE2
 O3
6kgk 1 O60341 99.4 0.0 X-RAY
 2020-03-25 TYR A:356 A:520 35.0 0.152 S -68.2 -52.9 35.0 0.152 0.0 GOL
 9.113
 CE2
 C3
6kgl 1 O60341 99.4 0.0 X-RAY
 2020-03-25 TYR A:356 A:520 35.0 0.152 S -68.9 -53.5 35.0 0.152 0.0 GOL
 9.114
 CE2
 C3
6kgm 1 O60341 99.4 0.0 X-RAY
 2020-03-25 TYR A:356 A:520 39.0 0.17 S -68.0 -52.0 39.0 0.17 0.0 GOL
GOL
 9.117
9.073
 CE2
O
 C3
O2
6kgn 1 O60341 99.4 0.0 X-RAY
 2020-03-25 TYR A:356 A:520 39.0 0.17 S -68.4 -52.0 39.0 0.17 0.0 GOL
GOL
 9.116
9.067
 CE2
O
 C3
O2
6kgo 1 O60341 99.4 0.0 X-RAY
 2020-03-25 TYR A:356 A:520 34.0 0.148 S -70.0 -53.6 34.0 0.148 0.0 GOL
HOH
 8.641
3.147
 CE2
CB
 O3
O
6kgp 1 O60341 99.4 0.0 X-RAY
 2020-03-25 TYR A:356 A:520 34.0 0.148 S -69.5 -54.0 34.0 0.148 0.0 GOL
HOH
 8.629
3.144
 CE2
CB
 O3
O
6kgq 1 O60341 99.4 0.0 X-RAY
 2020-03-25 TYR A:356 A:520 27.0 0.117 S -72.1 -50.5 27.0 0.117 0.0 HOH
 7.010
 CD2
 O
6kgr 1 O60341 99.4 0.0 X-RAY
 2020-03-25 TYR A:356 A:520 27.0 0.117 S -72.0 -50.4 27.0 0.117 0.0 HOH
 7.005
 CD2
 O
7cdc 1 O60341 99.4 0.0 X-RAY
 2021-06-23 TYR A:356 A:520 38.0 0.165 S -71.9 -55.8 38.0 0.165 0.0 GOL
HOH
 9.073
3.274
 CE2
N
 O3
O
7cdd 1 O60341 99.4 0.0 X-RAY
 2021-06-23 TYR A:356 A:520 37.0 0.161 S -71.5 -55.0 37.0 0.161 0.0 GOL
HOH
 9.227
3.359
 CE2
O
 C3
O
7cde 1 O60341 99.4 0.0 X-RAY
 2021-06-23 TYR A:356 A:520 37.0 0.161 S -68.1 -50.2 37.0 0.161 0.0 GOL
GOL
HOH
 9.180
9.483
3.237
 CE2
O
N
 C3
O2
O
7cdf 1 O60341 99.4 0.0 X-RAY
 2021-06-23 TYR A:356 A:520 38.0 0.165 S -71.7 -54.8 38.0 0.165 0.0 GOL
GOL
HOH
 9.158
9.247
3.124
 CE2
O
N
 C3
O2
O
7cdg 1 O60341 99.4 0.0 X-RAY
 2021-06-23 TYR A:356 A:520 33.0 0.143 S -71.5 -54.0 33.0 0.143 0.0 GOL
GOL
HOH
 9.078
9.186
3.424
 CE2
O
O
 C3
O2
O
2ejr 1 O60341 99.4 0.0 X-RAY
 2008-01-01 TYR A:349 A:520 33.0 0.143 S -72.9 -56.4 33.0 0.143 0.0 HOH
 6.289
 CD2
 O
2z3y 1 O60341 99.4 0.0 X-RAY
 2008-01-01 TYR A:349 A:520 34.0 0.148 S -72.0 -56.9 34.0 0.148 0.0 HOH
 7.180
 OH
 O
2z5u 1 O60341 99.4 0.0 X-RAY
 2008-04-01 TYR A:349 A:520 35.0 0.152 S -71.8 -53.4 35.0 0.152 0.0 HOH
 7.198
 OH
 O
3abt 1 O60341 99.4 0.0 X-RAY
 2010-07-07 TYR A:349 A:520 35.0 0.152 S -64.4 -57.3 35.0 0.152 0.0
3abu 1 O60341 99.4 0.0 X-RAY
 2010-07-07 TYR A:349 A:520 34.0 0.148 S -63.7 -53.0 34.0 0.148 0.0
6k3e 1 O60341 99.4 0.0 X-RAY
 2020-05-20 TYR A:349 A:520 39.0 0.17 S -81.3 -50.8 39.0 0.17 0.0 ACT
MLA
 9.571
8.764
 CE2
O
 CH3
O1A
2dw4 1 O60341 99.4 0.0 X-RAY
 2007-09-04 TYR A:349 A:520 33.0 0.143 S -72.6 -54.3 33.0 0.143 0.0 HOH
 3.734
 CD1
 O
6w4k 1 O60341 99.4 0.0 X-RAY
 2020-10-21 TYR A:347 A:520 31.0 0.135 S -75.4 -53.9 31.0 0.135 0.0
6nqm 1 O60341 99.4 0.0 X-RAY
 2019-02-13 TYR A:348 A:520 29.0 0.126 S -66.6 -43.4 29.0 0.126 0.0
6nqu 1 O60341 99.4 0.0 X-RAY
 2019-02-13 TYR A:348 A:520 29.0 0.126 S -78.0 -37.6 29.0 0.126 0.0
6nr5 1 O60341 99.4 0.0 X-RAY
 2019-07-17 TYR A:348 A:520 33.0 0.143 S -62.9 -53.3 33.0 0.143 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 TYR A:520 A:520 45.0 0.196 S -70.7 -44.4