Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23399895 . A C CCDS30627.1:NM_015013.3:c.1661cAg>cCg_NP_055828.2:p.554Q>P Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
 2013-06-12 GLN A:574 A:554 39.0 0.217 G -56.3 -28.9 39.0 0.217 0.0
3zmv 1 O60341 99.54 0.0 X-RAY
 2013-06-12 GLN A:574 A:554 33.0 0.183 T -48.5 -28.7 33.0 0.183 0.0
3zms 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLN A:574 A:554 38.0 0.211 T -59.2 -16.2 38.0 0.211 0.0
3zmt 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLN A:574 A:554 34.0 0.189 T -56.3 -24.3 34.0 0.189 0.0
3zmz 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLN A:574 A:554 39.0 0.217 G -52.3 -25.3 39.0 0.217 0.0
3zn0 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLN A:574 A:554 39.0 0.217 T -63.1 -15.3 39.0 0.217 0.0
3zn1 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLN A:574 A:554 37.0 0.206 T -53.3 -18.9 37.0 0.206 0.0
4czz 1 O60341 99.43 0.0 X-RAY
 2014-06-11 GLN A:574 A:554 39.0 0.217 G -56.4 -35.0 39.0 0.217 0.0
4uv8 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLN A:574 A:554 38.0 0.211 T -60.2 -19.4 38.0 0.211 0.0 D69
 7.393
 NE2
 CAC
4uv9 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLN A:574 A:554 38.0 0.211 T -49.7 -22.4 38.0 0.211 0.0 D70
 9.465
 NE2
 CAQ
4uva 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLN A:574 A:554 36.0 0.2 T -61.6 -22.1 36.0 0.2 0.0
4uvb 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLN A:574 A:554 36.0 0.2 T -61.5 -18.0 36.0 0.2 0.0
4uvc 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLN A:574 A:554 38.0 0.211 T -37.6 -28.2 38.0 0.211 0.0
6tuy 1 O60341 94.98 0.0 X-RAY
 2021-07-21 GLN A:554 A:554 39.0 0.217 T -44.7 -28.5 39.0 0.217 0.0 NY8
NY8
NY8
HOH
 5.349
7.867
8.142
8.199
 N
O
O
NE2
 CAC
CAB
CAD
O
2xaf 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:554 A:554 42.0 0.233 G -46.4 -28.3 42.0 0.233 0.0 TCF
 9.963
 NE2
 BR
2xag 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:554 A:554 41.0 0.228 G -60.7 -36.9 41.0 0.228 0.0
2xah 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:554 A:554 37.0 0.206 T -50.0 -29.7 37.0 0.206 0.0
2xaj 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:554 A:554 39.0 0.217 G -51.6 -38.3 39.0 0.217 0.0
2xaq 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:554 A:554 43.0 0.239 T -47.3 -40.3 43.0 0.239 0.0 M84
 7.237
 N
 CW6
2xas 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:554 A:554 45.0 0.25 T -51.2 -28.4 45.0 0.25 0.0 M80
 7.375
 C
 CW6
4uxn 1 O60341 94.98 0.0 X-RAY
 2015-02-25 GLN A:554 A:554 45.0 0.25 G -49.6 -31.9 45.0 0.25 0.0 M8A
 7.594
 C
 CG
5lhg 1 O60341 94.98 0.0 X-RAY
 2017-02-22 GLN A:554 A:554 37.0 0.206 G -73.9 -31.0 37.0 0.206 0.0 6X3
HOH
 5.684
6.200
 N
N
 S06
O
5lhh 1 O60341 94.98 0.0 X-RAY
 2017-02-22 GLN A:554 A:554 33.0 0.183 T -66.3 -23.0 33.0 0.183 0.0 GOL
6X0
HOH
 7.542
7.199
3.154
 C
NE2
NE2
 O2
N33
O
5lhi 1 O60341 94.98 0.0 X-RAY
 2017-02-22 GLN A:554 A:554 37.0 0.206 G -50.0 -32.6 37.0 0.206 0.0 6X5
 7.723
 N
 C25
6te1 1 O60341 94.98 0.0 X-RAY
 2020-06-03 GLN A:554 A:554 29.0 0.161 G -63.2 -23.9 29.0 0.161 0.0 N4K
N4K
 6.689
7.418
 N
NE2
 N24
N24
5l3c 1 O60341 94.86 0.0 X-RAY
 2016-05-04 GLN A:554 A:554 38.0 0.211 G -44.8 -37.8 38.0 0.211 0.0
5l3d 1 O60341 94.86 0.0 X-RAY
 2016-05-04 GLN A:554 A:554 40.0 0.222 T -55.7 -29.2 40.0 0.222 0.0 HOH
 3.915
 CB
 O
5l3b 1 O60341 94.86 0.0 X-RAY
 2016-05-04 GLN A:554 A:554 39.0 0.217 G -46.2 -39.8 39.0 0.217 0.0
2x0l 1 O60341 100.0 0.0 X-RAY
 2010-03-02 GLN A:436 A:554 44.0 0.244 T -53.9 -15.1 44.0 0.244 0.0
4bay 1 O60341 99.85 0.0 X-RAY
 2013-11-27 GLN A:388 A:554 35.0 0.194 G -60.4 -25.9 35.0 0.194 0.0
2v1d 1 O60341 99.42 0.0 X-RAY
 2007-05-29 GLN A:432 A:554 42.0 0.233 T -55.4 -7.5 42.0 0.233 0.0
2y48 1 O60341 99.42 0.0 X-RAY
 2011-02-16 GLN A:432 A:554 38.0 0.211 T -53.9 -18.9 38.0 0.211 0.0
5l3e 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLN A:432 A:554 37.0 0.206 G -51.0 -32.8 37.0 0.206 0.0 E11
E11
E11
E11
 7.575
9.507
9.506
8.262
 N
N
O
O
 N3
N3
CBI
CBE
5l3f 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLN A:432 A:554 34.0 0.189 G -76.0 -21.9 34.0 0.189 0.0
5l3g 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLN A:432 A:554 37.0 0.206 G -56.6 -17.9 37.0 0.206 0.0
5lbq 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLN A:432 A:554 34.0 0.189 G -53.5 -37.1 34.0 0.189 0.0 767
767
767
 7.307
9.212
9.568
 N
N
O
 C3
N6
C26
5lgt 1 O60341 99.42 0.0 X-RAY
 2017-02-22 GLN A:432 A:554 39.0 0.217 G -52.1 -32.4 39.0 0.217 0.0 6W3
 7.392
 NE2
 CAA
5lgu 1 O60341 99.42 0.0 X-RAY
 2017-02-22 GLN A:432 A:554 33.0 0.183 G -54.0 -27.0 33.0 0.183 0.0 6W1
 6.957
 NE2
 N2
6vyp 7 O60341 98.69 0.0 X-RAY
 2020-05-27 GLN S:386 M:554 35.0 0.194 T -69.8 -17.7 35.0 0.194 0.0
GLN U:386 m:554 32.0 0.178 T -69.5 -18.2 NA NA NA
GLN W:386 K:554 35.0 0.194 T -66.7 -26.5 35.0 0.194 0.0
GLN Y:386 k:554 38.0 0.211 T -68.2 -25.9 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
 2017-02-22 GLN A:388 A:558 34.0 0.189 G -63.1 -35.2 34.0 0.189 0.0
2iw5 1 O60341 99.4 0.0 X-RAY
 2006-08-09 GLN A:384 A:554 38.0 0.211 T -58.6 -24.4 38.0 0.211 0.0 HOH
 2.566
 O
 O
2uxn 1 O60341 99.4 0.0 X-RAY
 2007-05-29 GLN A:384 A:554 41.0 0.228 T -65.8 -29.7 41.0 0.228 0.0 HOH
 3.553
 CB
 O
2uxx 1 O60341 99.4 0.0 X-RAY
 2007-08-21 GLN A:384 A:554 38.0 0.211 T -67.7 -23.5 38.0 0.211 0.0
4kum 1 O60341 99.4 0.0 X-RAY
 2014-05-07 GLN A:384 A:554 32.0 0.178 T -60.1 -23.0 32.0 0.178 0.0 THG
HOH
 9.708
3.924
 NE2
CB
 C7
O
4xbf 1 O60341 99.4 0.0 X-RAY
 2016-04-27 GLN A:384 A:554 42.0 0.233 G -63.9 -37.0 42.0 0.233 0.0 HOH
 2.876
 OE1
 O
6wc6 1 O60341 99.4 0.0 X-RAY
 2021-06-30 GLN A:384 A:554 37.0 0.206 G -67.5 -41.3 37.0 0.206 0.0
2h94 1 O60341 99.4 0.0 X-RAY
 2006-07-04 GLN A:383 A:554 35.0 0.194 T -12.0 -38.9 35.0 0.194 0.0
2hko 1 O60341 99.25 0.0 X-RAY
 2006-08-29 GLN A:383 A:554 30.0 0.167 G -82.1 -24.1 30.0 0.167 0.0 HOH
 6.539
 OE1
 O
7e0g 1 O60341 99.1 0.0 X-RAY
 2021-03-24 GLN A:386 A:554 30.0 0.167 T -55.7 -22.1 30.0 0.167 0.0 HOH
 2.700
 OE1
 O
6s35 1 O60341 99.4 0.0 X-RAY
 2020-02-26 GLN A:387 A:554 41.0 0.228 S -75.9 -41.1 41.0 0.228 0.0
5h6q 1 O60341 99.4 0.0 X-RAY
 2017-04-12 GLN A:390 A:554 40.0 0.222 T -64.5 -18.8 40.0 0.222 0.0 HOH
 5.573
 N
 O
5h6r 1 O60341 99.4 0.0 X-RAY
 2017-04-12 GLN A:390 A:554 38.0 0.211 T -63.4 -22.8 38.0 0.211 0.0 HOH
 2.691
 OE1
 O
5x60 1 O60341 99.4 0.0 X-RAY
 2017-04-12 GLN A:390 A:554 40.0 0.222 T -58.6 -23.5 40.0 0.222 0.0 HOH
 2.665
 OE1
 O
5yjb 1 O60341 99.4 0.0 X-RAY
 2018-07-04 GLN A:390 A:554 36.0 0.2 G -60.7 -34.8 36.0 0.2 0.0 8WC
 7.160
 NE2
 N1
6kgk 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:390 A:554 41.0 0.228 G -87.3 -27.7 41.0 0.228 0.0 DJ0
HOH
 9.829
5.505
 NE2
N
 F1
O
6kgl 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:390 A:554 42.0 0.233 G -85.2 -31.8 42.0 0.233 0.0 DJ0
HOH
 9.485
5.543
 NE2
N
 F1
O
6kgm 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:390 A:554 41.0 0.228 T -76.0 -21.6 41.0 0.228 0.0 DJ0
HOH
 9.875
4.053
 NE2
OE1
 F1
O
6kgn 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:390 A:554 41.0 0.228 T -76.2 -21.6 41.0 0.228 0.0 DJ0
HOH
 9.406
4.026
 NE2
OE1
 F1
O
6kgo 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:390 A:554 39.0 0.217 T -62.2 -18.6 39.0 0.217 0.0 DJ0
HOH
 9.655
2.579
 NE2
OE1
 F1
O
6kgp 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:390 A:554 38.0 0.211 T -62.1 -19.1 38.0 0.211 0.0 DJ0
HOH
 9.218
2.587
 NE2
OE1
 F1
O
6kgq 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:390 A:554 36.0 0.2 T -65.6 -15.6 36.0 0.2 0.0 DJC
HOH
 8.965
2.740
 C
OE1
 F
O
6kgr 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:390 A:554 36.0 0.2 T -65.6 -15.6 36.0 0.2 0.0 DJC
HOH
 8.880
2.707
 C
OE1
 F
O
7cdc 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLN A:390 A:554 39.0 0.217 T -60.8 -19.0 39.0 0.217 0.0 HOH
 6.590
 NE2
 O
7cdd 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLN A:390 A:554 38.0 0.211 T -57.0 -23.5 38.0 0.211 0.0 HOH
 6.591
 NE2
 O
7cde 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLN A:390 A:554 38.0 0.211 T -59.4 -19.6 38.0 0.211 0.0 HOH
 6.918
 NE2
 O
7cdf 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLN A:390 A:554 38.0 0.211 T -57.8 -19.8 38.0 0.211 0.0 HOH
 6.785
 NE2
 O
7cdg 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLN A:390 A:554 38.0 0.211 T -64.1 -18.6 38.0 0.211 0.0 HOH
 9.702
 CB
 O
2ejr 1 O60341 99.4 0.0 X-RAY
 2008-01-01 GLN A:383 A:554 39.0 0.217 T -43.8 -26.9 39.0 0.217 0.0 HOH
 2.685
 CG
 O
2z3y 1 O60341 99.4 0.0 X-RAY
 2008-01-01 GLN A:383 A:554 39.0 0.217 T -42.8 -32.3 39.0 0.217 0.0 HOH
 2.900
 CG
 O
2z5u 1 O60341 99.4 0.0 X-RAY
 2008-04-01 GLN A:383 A:554 37.0 0.206 T -47.6 -29.9 37.0 0.206 0.0 HOH
 2.782
 CG
 O
3abt 1 O60341 99.4 0.0 X-RAY
 2010-07-07 GLN A:383 A:554 36.0 0.2 G -56.9 -38.7 36.0 0.2 0.0
3abu 1 O60341 99.4 0.0 X-RAY
 2010-07-07 GLN A:383 A:554 41.0 0.228 T -47.7 -26.4 41.0 0.228 0.0
6k3e 1 O60341 99.4 0.0 X-RAY
 2020-05-20 GLN A:383 A:554 32.0 0.178 G -78.8 -31.0 32.0 0.178 0.0 CW0
EDO
PEG
CVO
HOH
 5.986
4.403
8.309
6.192
7.283
 NE2
CA
N
NE2
C
 C2
C1
O4
C2
O
2dw4 1 O60341 99.4 0.0 X-RAY
 2007-09-04 GLN A:383 A:554 40.0 0.222 T -55.1 -23.4 40.0 0.222 0.0 HOH
 2.676
 CG
 O
6w4k 1 O60341 99.4 0.0 X-RAY
 2020-10-21 GLN A:381 A:554 36.0 0.2 T -55.8 -24.5 36.0 0.2 0.0 V0Y
HOH
 5.872
8.445
 NE2
NE2
 N33
O
6nqm 1 O60341 99.4 0.0 X-RAY
 2019-02-13 GLN A:382 A:554 31.0 0.172 T -60.4 -21.1 31.0 0.172 0.0
6nqu 1 O60341 99.4 0.0 X-RAY
 2019-02-13 GLN A:382 A:554 36.0 0.2 T -63.3 -13.3 36.0 0.2 0.0
6nr5 1 O60341 99.4 0.0 X-RAY
 2019-07-17 GLN A:382 A:554 38.0 0.211 G -69.8 -26.5 38.0 0.211 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 GLN A:554 A:554 37.0 0.206 T -78.8 -7.0