Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23403722 . A C CCDS30627.1:NM_015013.3:c.1664gAt>gCt_NP_055828.2:p.555D>A Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
 2013-06-12 ASP A:575 A:555 51.0 0.34 G -82.5 15.5 10.0 0.067 0.273 C:None:0.273
3zmv 1 O60341 99.54 0.0 X-RAY
 2013-06-12 ASP A:575 A:555 53.0 0.353 T -88.4 16.3 14.0 0.093 0.26 C:None:0.26
3zms 1 O60341 99.43 0.0 X-RAY
 2013-06-12 ASP A:575 A:555 51.0 0.34 T -97.2 15.0 20.0 0.133 0.207 C:Q01101:0.207
 FAD
 9.994
 OD2
 O2
3zmt 1 O60341 99.43 0.0 X-RAY
 2013-06-12 ASP A:575 A:555 49.0 0.327 T -86.8 12.7 9.0 0.06 0.267 C:None:0.267
 FAD
 9.987
 OD2
 O2
3zmz 1 O60341 99.43 0.0 X-RAY
 2013-06-12 ASP A:575 A:555 51.0 0.34 G -86.5 14.8 12.0 0.08 0.26 C:None:0.26
3zn0 1 O60341 99.43 0.0 X-RAY
 2013-06-12 ASP A:575 A:555 52.0 0.347 T -98.1 8.4 13.0 0.087 0.26 C:None:0.26
 FAD
 9.818
 OD2
 O2
3zn1 1 O60341 99.43 0.0 X-RAY
 2013-06-12 ASP A:575 A:555 47.0 0.313 T -93.0 9.1 3.0 0.02 0.293 C:None:0.293
4czz 1 O60341 99.43 0.0 X-RAY
 2014-06-11 ASP A:575 A:555 54.0 0.36 G -77.1 18.7 54.0 0.36 0.0 FAD
 9.944
 OD2
 O2
4uv8 1 O60341 99.43 0.0 X-RAY
 2014-09-10 ASP A:575 A:555 51.0 0.34 T -100.8 22.5 51.0 0.34 0.0 D69
 3.317
 OD2
 CAG
4uv9 1 O60341 99.43 0.0 X-RAY
 2014-09-10 ASP A:575 A:555 50.0 0.333 T -93.0 9.5 50.0 0.333 0.0 D70
 5.258
 OD2
 CAQ
4uva 1 O60341 99.43 0.0 X-RAY
 2014-09-10 ASP A:575 A:555 50.0 0.333 T -97.4 18.0 50.0 0.333 0.0 D73
 6.156
 OD2
 CAN
4uvb 1 O60341 99.43 0.0 X-RAY
 2014-09-10 ASP A:575 A:555 49.0 0.327 T -101.9 17.3 49.0 0.327 0.0 D51
 6.715
 OD2
 CAB
4uvc 1 O60341 99.43 0.0 X-RAY
 2014-09-10 ASP A:575 A:555 54.0 0.36 T -86.4 14.2 54.0 0.36 0.0 D52
 9.027
 OD2
 CAE
6tuy 1 O60341 94.98 0.0 X-RAY
 2021-07-21 ASP A:555 A:555 43.0 0.287 T -93.5 10.3 43.0 0.287 0.0 NY8
NY8
NY8
 2.920
4.941
8.025
 OD2
OD2
O
 NBL
CAI
CAP
2xaf 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:555 A:555 52.0 0.347 G -77.7 -9.4 52.0 0.347 0.0 TCF
 5.226
 OD2
 BR
2xag 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:555 A:555 57.0 0.38 G -66.4 17.2 57.0 0.38 0.0 TCF
 5.607
 OD2
 BR
2xah 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:555 A:555 56.0 0.373 T -87.1 17.8 56.0 0.373 0.0 3PL
 8.814
 OD2
 O
2xaj 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:555 A:555 53.0 0.353 G -71.5 7.5 53.0 0.353 0.0 TCA
 6.969
 OD2
 C33
2xaq 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:555 A:555 51.0 0.34 T -93.6 39.5 51.0 0.34 0.0 M84
 3.960
 O
 CW5
2xas 1 O60341 94.98 0.0 X-RAY
 2010-05-05 ASP A:555 A:555 60.0 0.4 T -78.2 23.1 60.0 0.4 0.0 M80
 3.250
 O
 CW6
4uxn 1 O60341 94.98 0.0 X-RAY
 2015-02-25 ASP A:555 A:555 19.0 0.127 G -85.1 13.5 19.0 0.127 0.0 M8A
 2.881
 OD2
 CB
5lhg 1 O60341 94.98 0.0 X-RAY
 2017-02-22 ASP A:555 A:555 47.0 0.313 G -87.2 16.7 47.0 0.313 0.0 FAD
6X3
6X3
HOH
 9.813
7.791
3.112
8.565
 OD2
OD2
OD1
N
 O2
C05
S06
O
5lhh 1 O60341 94.98 0.0 X-RAY
 2017-02-22 ASP A:555 A:555 57.0 0.38 T -89.4 9.7 57.0 0.38 0.0 FAD
GOL
6X0
HOH
 9.870
3.480
2.849
2.803
 OD2
O
OD2
OD2
 O2
O2
N33
O
5lhi 1 O60341 94.98 0.0 X-RAY
 2017-02-22 ASP A:555 A:555 45.0 0.3 G -84.6 3.5 45.0 0.3 0.0 FAD
6X5
 9.956
3.234
 OD2
OD2
 O2
C25
6te1 1 O60341 94.98 0.0 X-RAY
 2020-06-03 ASP A:555 A:555 48.0 0.32 G -88.1 5.0 48.0 0.32 0.0 N4K
N4K
FAD
 4.609
3.228
9.879
 OD1
OD2
OD2
 N24
N24
O2
5l3c 1 O60341 94.86 0.0 X-RAY
 2016-05-04 ASP A:555 A:555 54.0 0.36 G -78.6 16.2 54.0 0.36 0.0 FAD
 9.993
 OD2
 O2
5l3d 1 O60341 94.86 0.0 X-RAY
 2016-05-04 ASP A:555 A:555 51.0 0.34 T -88.7 9.0 51.0 0.34 0.0 HOH
 4.559
 OD2
 O
5l3b 1 O60341 94.86 0.0 X-RAY
 2016-05-04 ASP A:555 A:555 52.0 0.347 G -66.0 -3.2 52.0 0.347 0.0 FAD
 9.918
 OD2
 O2
2x0l 1 O60341 100.0 0.0 X-RAY
 2010-03-02 ASP A:437 A:555 51.0 0.34 T -98.3 13.0 3.0 0.02 0.32 C:Q5TEC6:0.32
4bay 1 O60341 99.85 0.0 X-RAY
 2013-11-27 ASP A:389 A:555 43.0 0.287 G -90.5 12.4 43.0 0.287 0.0 FAD
 9.870
 OD2
 O2
2v1d 1 O60341 99.42 0.0 X-RAY
 2007-05-29 ASP A:433 A:555 45.0 0.3 T -102.6 4.9 4.0 0.027 0.273 C:Q16695:0.273
2y48 1 O60341 99.42 0.0 X-RAY
 2011-02-16 ASP A:433 A:555 54.0 0.36 T -91.0 13.2 13.0 0.087 0.273 C:O95863:0.273
 FAD
 9.863
 OD2
 O2
5l3e 1 O60341 99.42 0.0 X-RAY
 2016-09-21 ASP A:433 A:555 58.0 0.387 G -78.2 8.1 58.0 0.387 0.0 E11
E11
E11
E11
 3.723
7.349
8.415
8.119
 OD2
O
O
O
 NAR
CBI
CBI
CAW
5l3f 1 O60341 99.42 0.0 X-RAY
 2016-09-21 ASP A:433 A:555 61.0 0.407 G -77.5 -3.8 19.0 0.127 0.28 C:None:0.28
 FAD
 9.936
 OD2
 O2
5l3g 1 O60341 99.42 0.0 X-RAY
 2016-09-21 ASP A:433 A:555 64.0 0.427 G -81.0 -5.0 21.0 0.14 0.287 C:None:0.287
 FAD
 9.775
 OD2
 O2
5lbq 1 O60341 99.42 0.0 X-RAY
 2016-09-21 ASP A:433 A:555 54.0 0.36 G -65.9 -11.9 54.0 0.36 0.0 FAD
767
767
767
 9.876
3.060
6.687
8.345
 OD2
OD2
OD2
O
 O2
C3
C26
C26
5lgt 1 O60341 99.42 0.0 X-RAY
 2017-02-22 ASP A:433 A:555 62.0 0.413 G -76.5 6.6 62.0 0.413 0.0 6W3
 3.645
 OD2
 NBG
5lgu 1 O60341 99.42 0.0 X-RAY
 2017-02-22 ASP A:433 A:555 57.0 0.38 G -83.6 5.5 57.0 0.38 0.0 6W1
 2.918
 OD2
 N2
6vyp 7 O60341 98.69 0.0 X-RAY
 2020-05-27 ASP S:387 M:555 42.0 0.28 T -103.1 12.4 3.0 0.02 0.26 E:A0A310TTQ1:0.26
ASP U:387 m:555 45.0 0.3 T -104.1 11.9 NA NA NA
ASP W:387 K:555 43.0 0.287 T -98.4 14.8 12.0 0.08 0.207 A:A0A310TTQ1:0.207
ASP Y:387 k:555 49.0 0.327 T -96.9 12.8 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
 2017-02-22 ASP A:389 A:559 52.0 0.347 G -71.5 7.7 52.0 0.347 0.0 6W0
 8.354
 OD2
 CAE
2iw5 1 O60341 99.4 0.0 X-RAY
 2006-08-09 ASP A:385 A:555 44.0 0.293 T -99.9 7.7 44.0 0.293 0.0 HOH
 2.638
 OD2
 O
2uxn 1 O60341 99.4 0.0 X-RAY
 2007-05-29 ASP A:385 A:555 47.0 0.313 T -94.2 7.2 21.0 0.14 0.173 C:P68431:0.173
 HOH
 4.592
 OD2
 O
2uxx 1 O60341 99.4 0.0 X-RAY
 2007-08-21 ASP A:385 A:555 43.0 0.287 T -100.3 12.2 43.0 0.287 0.0 FAJ
 7.450
 OD2
 C10
4kum 1 O60341 99.4 0.0 X-RAY
 2014-05-07 ASP A:385 A:555 48.0 0.32 T -97.4 2.6 48.0 0.32 0.0 THG
HOH
 5.530
7.179
 OD2
N
 N8
O
4xbf 1 O60341 99.4 0.0 X-RAY
 2016-04-27 ASP A:385 A:555 43.0 0.287 G -96.5 24.3 43.0 0.287 0.0 HOH
 7.679
 N
 O
6wc6 1 O60341 99.4 0.0 X-RAY
 2021-06-30 ASP A:385 A:555 44.0 0.293 G -82.1 -0.6 44.0 0.293 0.0 FAD
 9.999
 OD2
 O2
2h94 1 O60341 99.4 0.0 X-RAY
 2006-07-04 ASP A:384 A:555 44.0 0.293 T -86.3 -11.1 44.0 0.293 0.0 HOH
 7.221
 O
 O
2hko 1 O60341 99.25 0.0 X-RAY
 2006-08-29 ASP A:384 A:555 51.0 0.34 G -79.4 1.1 51.0 0.34 0.0 HOH
 2.770
 OD1
 O
7e0g 1 O60341 99.1 0.0 X-RAY
 2021-03-24 ASP A:387 A:555 39.0 0.26 T -95.4 -0.9 39.0 0.26 0.0 HOH
 2.693
 OD2
 O
6s35 1 O60341 99.4 0.0 X-RAY
 2020-02-26 ASP A:388 A:555 51.0 0.34 G -76.4 2.8 51.0 0.34 0.0
5h6q 1 O60341 99.4 0.0 X-RAY
 2017-04-12 ASP A:391 A:555 46.0 0.307 T -92.2 4.0 3.0 0.02 0.287 C:None:0.287
 HOH
 6.517
 N
 O
5h6r 1 O60341 99.4 0.0 X-RAY
 2017-04-12 ASP A:391 A:555 53.0 0.353 T -96.6 16.3 14.0 0.093 0.26 C:None:0.26
 HOH
 3.163
 OD2
 O
5x60 1 O60341 99.4 0.0 X-RAY
 2017-04-12 ASP A:391 A:555 49.0 0.327 T -91.0 8.3 2.0 0.013 0.314 C:None:0.313
 HOH
 3.345
 O
 O
5yjb 1 O60341 99.4 0.0 X-RAY
 2018-07-04 ASP A:391 A:555 62.0 0.413 G -69.8 -4.3 62.0 0.413 0.0 FAD
8WC
 9.843
3.278
 OD2
OD2
 O2
N1
6kgk 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:391 A:555 47.0 0.313 G -77.0 8.7 47.0 0.313 0.0 DJ0
HOH
 5.423
2.504
 OD2
OD2
 F1
O
6kgl 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:391 A:555 45.0 0.3 G -72.6 4.5 45.0 0.3 0.0 DJ0
HOH
 5.177
2.506
 OD2
OD2
 F1
O
6kgm 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:391 A:555 56.0 0.373 T -86.6 12.3 56.0 0.373 0.0 DJ0
HOH
 5.691
2.489
 OD2
OD2
 F1
O
6kgn 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:391 A:555 56.0 0.373 T -86.3 11.9 56.0 0.373 0.0 DJ0
HOH
 5.270
2.501
 OD2
OD2
 F1
O
6kgo 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:391 A:555 47.0 0.313 T -95.9 8.1 47.0 0.313 0.0 DJ0
HOH
 6.086
2.738
 OD2
OD2
 F1
O
6kgp 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:391 A:555 48.0 0.32 T -95.4 8.3 48.0 0.32 0.0 DJ0
HOH
 5.626
2.751
 OD2
OD2
 F1
O
6kgq 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:391 A:555 43.0 0.287 T -96.1 5.1 43.0 0.287 0.0 DJC
HOH
 4.112
2.868
 OD2
OD2
 F
O
6kgr 1 O60341 99.4 0.0 X-RAY
 2020-03-25 ASP A:391 A:555 44.0 0.293 T -96.0 5.3 44.0 0.293 0.0 DJC
HOH
 4.100
2.877
 OD2
OD2
 F
O
7cdc 1 O60341 99.4 0.0 X-RAY
 2021-06-23 ASP A:391 A:555 48.0 0.32 T -96.3 14.3 6.0 0.04 0.28 C:None:0.28
 HOH
 2.769
 OD2
 O
7cdd 1 O60341 99.4 0.0 X-RAY
 2021-06-23 ASP A:391 A:555 50.0 0.333 T -90.4 10.0 7.0 0.047 0.286 C:None:0.287
 HOH
 2.846
 OD2
 O
7cde 1 O60341 99.4 0.0 X-RAY
 2021-06-23 ASP A:391 A:555 50.0 0.333 T -95.3 14.9 11.0 0.073 0.26 C:None:0.26
 HOH
 3.113
 OD2
 O
7cdf 1 O60341 99.4 0.0 X-RAY
 2021-06-23 ASP A:391 A:555 47.0 0.313 T -94.1 7.2 7.0 0.047 0.266 C:None:0.267
 HOH
 2.975
 OD2
 O
7cdg 1 O60341 99.4 0.0 X-RAY
 2021-06-23 ASP A:391 A:555 47.0 0.313 T -96.0 6.5 7.0 0.047 0.266 C:None:0.267
 HOH
 8.736
 O
 O
2ejr 1 O60341 99.4 0.0 X-RAY
 2008-01-01 ASP A:384 A:555 44.0 0.293 T -103.7 -3.6 44.0 0.293 0.0 F2N
HOH
 6.782
3.191
 OD2
OD2
 CCH
O
2z3y 1 O60341 99.4 0.0 X-RAY
 2008-01-01 ASP A:384 A:555 45.0 0.3 T -101.3 3.3 45.0 0.3 0.0 F2N
HOH
 6.900
2.629
 OD2
OD1
 CCI
O
2z5u 1 O60341 99.4 0.0 X-RAY
 2008-04-01 ASP A:384 A:555 45.0 0.3 T -100.8 2.0 45.0 0.3 0.0 FAJ
HOH
 7.209
2.741
 OD2
OD2
 C8
O
3abt 1 O60341 99.4 0.0 X-RAY
 2010-07-07 ASP A:384 A:555 52.0 0.347 G -82.9 2.2 52.0 0.347 0.0 2PF
 6.413
 OD2
 FAC
3abu 1 O60341 99.4 0.0 X-RAY
 2010-07-07 ASP A:384 A:555 44.0 0.293 T -102.3 1.5 44.0 0.293 0.0 12F
 7.229
 OD2
 CAP
6k3e 1 O60341 99.4 0.0 X-RAY
 2020-05-20 ASP A:384 A:555 58.0 0.387 G -69.4 -5.7 58.0 0.387 0.0 CW0
D3U
EDO
PEG
CVO
HOH
 3.224
7.405
5.885
7.891
3.635
3.567
 OD2
OD1
N
OD1
OD1
O
 C2
CCH
C1
O4
C4
O
2dw4 1 O60341 99.4 0.0 X-RAY
 2007-09-04 ASP A:384 A:555 43.0 0.287 T -101.5 2.1 43.0 0.287 0.0 HOH
 2.875
 OD2
 O
6w4k 1 O60341 99.4 0.0 X-RAY
 2020-10-21 ASP A:382 A:555 52.0 0.347 T -83.8 6.8 52.0 0.347 0.0 V0Y
HOH
 2.883
6.744
 OD2
OD2
 C29
O
6nqm 1 O60341 99.4 0.0 X-RAY
 2019-02-13 ASP A:383 A:555 45.0 0.3 T -97.8 7.4 45.0 0.3 0.0 FAD
 9.961
 OD1
 O2
6nqu 1 O60341 99.4 0.0 X-RAY
 2019-02-13 ASP A:383 A:555 37.0 0.247 T -102.5 5.7 37.0 0.247 0.0 KWM
 7.067
 OD1
 C10
6nr5 1 O60341 99.4 0.0 X-RAY
 2019-07-17 ASP A:383 A:555 45.0 0.3 G -74.9 -8.0 45.0 0.3 0.0 KXM
 8.503
 OD1
 C14

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 ASP A:555 A:555 20.0 0.133 T -108.3 0.4