Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 23405516 | . | C | A | CCDS30627.1:NM_015013.3:c.1829aCg>aAg_NP_055828.2:p.610T>K | Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3zmu | 1 | O60341 | 99.54 | 0.0 |
X-RAY |
2013-06-12 | THR | A:630 | A:610 | 82.0 | 0.586 | T | -69.3 | -1.8 | 82.0 | 0.586 | 0.0 | ||||||
| 3zmv | 1 | O60341 | 99.54 | 0.0 |
X-RAY |
2013-06-12 | THR | A:630 | A:610 | 88.0 | 0.629 | T | -68.0 | -29.0 | 88.0 | 0.629 | 0.0 | ||||||
| 3zms | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | THR | A:630 | A:610 | 82.0 | 0.586 | T | -73.7 | 4.8 | 82.0 | 0.586 | 0.0 | ||||||
| 3zmt | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | THR | A:630 | A:610 | 84.0 | 0.6 | T | -72.8 | 0.4 | 84.0 | 0.6 | 0.0 | ||||||
| 3zmz | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | THR | A:630 | A:610 | 79.0 | 0.564 | T | -71.0 | -15.1 | 79.0 | 0.564 | 0.0 | ||||||
| 3zn0 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | THR | A:630 | A:610 | 80.0 | 0.571 | T | -68.0 | -13.7 | 80.0 | 0.571 | 0.0 | ||||||
| 3zn1 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | THR | A:630 | A:610 | 82.0 | 0.586 | T | -69.7 | -7.7 | 82.0 | 0.586 | 0.0 | ||||||
| 4czz | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-06-11 | THR | A:630 | A:610 | 73.0 | 0.521 | T | -82.9 | -2.9 | 73.0 | 0.521 | 0.0 | ||||||
| 4uv8 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | THR | A:630 | A:610 | 82.0 | 0.586 | T | -68.6 | -12.8 | 82.0 | 0.586 | 0.0 | ||||||
| 4uv9 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | THR | A:630 | A:610 | 76.0 | 0.543 | T | -77.1 | -13.5 | 76.0 | 0.543 | 0.0 | ||||||
| 4uva | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | THR | A:630 | A:610 | 84.0 | 0.6 | T | -67.0 | -14.2 | 84.0 | 0.6 | 0.0 | ||||||
| 4uvb | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | THR | A:630 | A:610 | 84.0 | 0.6 | T | -66.0 | -15.5 | 84.0 | 0.6 | 0.0 | ||||||
| 4uvc | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | THR | A:630 | A:610 | 79.0 | 0.564 | T | -69.1 | -24.0 | 79.0 | 0.564 | 0.0 | ||||||
| 6tuy | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2021-07-21 | THR | A:610 | A:610 | 81.0 | 0.579 | T | -81.0 | 34.8 | 81.0 | 0.579 | 0.0 |
GOL |
9.116 |
CG2 |
C1 |
||
| 2xaf | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | THR | A:610 | A:610 | 81.0 | 0.579 | T | -70.7 | -36.7 | 81.0 | 0.579 | 0.0 | ||||||
| 2xag | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | THR | A:610 | A:610 | 76.0 | 0.543 | T | -80.9 | -4.9 | 76.0 | 0.543 | 0.0 | ||||||
| 2xah | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | THR | A:610 | A:610 | 76.0 | 0.543 | T | -80.0 | 0.3 | 76.0 | 0.543 | 0.0 | ||||||
| 2xaj | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | THR | A:610 | A:610 | 79.0 | 0.564 | T | -82.5 | -9.6 | 79.0 | 0.564 | 0.0 | ||||||
| 2xaq | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | THR | A:610 | A:610 | 70.0 | 0.5 | T | -90.4 | 0.5 | 70.0 | 0.5 | 0.0 | ||||||
| 2xas | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | THR | A:610 | A:610 | 78.0 | 0.557 | T | -87.7 | 6.3 | 78.0 | 0.557 | 0.0 | ||||||
| 4uxn | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2015-02-25 | THR | A:610 | A:610 | 89.0 | 0.636 | T | -53.1 | -35.8 | 89.0 | 0.636 | 0.0 | ||||||
| 5lhg | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | THR | A:610 | A:610 | 79.0 | 0.564 | E | -65.7 | -5.1 | 79.0 | 0.564 | 0.0 | ||||||
| 5lhh | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | THR | A:610 | A:610 | 82.0 | 0.586 | T | -68.8 | 3.9 | 82.0 | 0.586 | 0.0 | ||||||
| 5lhi | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | THR | A:610 | A:610 | 83.0 | 0.593 | T | -78.7 | -8.9 | 83.0 | 0.593 | 0.0 | ||||||
| 6te1 | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2020-06-03 | THR | A:610 | A:610 | 79.0 | 0.564 | T | -70.8 | -11.5 | 79.0 | 0.564 | 0.0 | ||||||
| 5l3c | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | THR | A:610 | A:610 | 84.0 | 0.6 | T | -70.1 | -19.6 | 84.0 | 0.6 | 0.0 | ||||||
| 5l3d | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | THR | A:610 | A:610 | 77.0 | 0.55 | T | -69.9 | -10.8 | 77.0 | 0.55 | 0.0 |
HOH |
8.878 |
N |
O |
||
| 5l3b | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | THR | A:610 | A:610 | 84.0 | 0.6 | T | -65.2 | -14.9 | 84.0 | 0.6 | 0.0 | ||||||
| 2x0l | 1 | O60341 | 100.0 | 0.0 |
X-RAY |
2010-03-02 | THR | A:492 | A:610 | 79.0 | 0.564 | E | -76.4 | 21.6 | 79.0 | 0.564 | 0.0 | ||||||
| 4bay | 1 | O60341 | 99.85 | 0.0 |
X-RAY |
2013-11-27 | THR | A:444 | A:610 | 82.0 | 0.586 | T | -73.9 | -1.8 | 82.0 | 0.586 | 0.0 | ||||||
| 2v1d | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2007-05-29 | THR | A:488 | A:610 | 74.0 | 0.529 | T | -79.1 | -18.2 | 74.0 | 0.529 | 0.0 | ||||||
| 2y48 | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2011-02-16 | THR | A:488 | A:610 | 81.0 | 0.579 | T | -83.3 | 23.7 | 81.0 | 0.579 | 0.0 | ||||||
| 5l3e | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | THR | A:488 | A:610 | 82.0 | 0.586 | T | -76.0 | -6.9 | 82.0 | 0.586 | 0.0 | ||||||
| 5l3f | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | THR | A:488 | A:610 | 89.0 | 0.636 | T | -74.2 | 26.6 | 89.0 | 0.636 | 0.0 | ||||||
| 5l3g | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | THR | A:488 | A:610 | 82.0 | 0.586 | T | -79.4 | 48.2 | 82.0 | 0.586 | 0.0 | ||||||
| 5lbq | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | THR | A:488 | A:610 | 84.0 | 0.6 | T | -52.4 | -29.2 | 84.0 | 0.6 | 0.0 | ||||||
| 5lgt | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2017-02-22 | THR | A:488 | A:610 | 90.0 | 0.643 | T | -49.7 | -33.2 | 90.0 | 0.643 | 0.0 | ||||||
| 5lgu | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2017-02-22 | THR | A:488 | A:610 | 87.0 | 0.621 | T | -56.9 | -25.6 | 87.0 | 0.621 | 0.0 | ||||||
| 6vyp | 7 | O60341 | 98.69 | 0.0 |
X-RAY |
2020-05-27 | THR | S:442 | M:610 | 123.0 | 0.879 | T | -139.6 | -38.7 | 123.0 | 0.879 | 0.0 | ||||||
| THR | U:442 | m:610 | 98.0 | 0.7 | S | -82.7 | 53.2 | NA | NA | NA | |||||||||||||
| THR | W:442 | K:610 | 94.0 | 0.671 | T | -66.4 | -12.6 | 94.0 | 0.671 | 0.0 | |||||||||||||
| THR | Y:442 | k:610 | 94.0 | 0.671 | T | -67.0 | -15.2 | NA | NA | NA | |||||||||||||
| 5lgn | 1 | O60341 | 99.85 | 0.0 |
X-RAY |
2017-02-22 | THR | A:444 | A:614 | 73.0 | 0.521 | T | -69.2 | -23.4 | 73.0 | 0.521 | 0.0 | ||||||
| 2iw5 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2006-08-09 | THR | A:440 | A:610 | 85.0 | 0.607 | E | -49.9 | -27.8 | 85.0 | 0.607 | 0.0 |
HOH |
6.487 |
O |
O |
||
| 2uxn | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-05-29 | THR | A:440 | A:610 | 88.0 | 0.629 | T | -49.0 | -22.6 | 88.0 | 0.629 | 0.0 |
HOH |
8.183 |
N |
O |
||
| 2uxx | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-08-21 | THR | A:440 | A:610 | 88.0 | 0.629 | T | -47.9 | -26.3 | 88.0 | 0.629 | 0.0 | ||||||
| 4kum | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2014-05-07 | THR | A:440 | A:610 | 85.0 | 0.607 | E | -53.7 | -22.9 | 85.0 | 0.607 | 0.0 | ||||||
| 4xbf | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2016-04-27 | THR | A:440 | A:610 | 84.0 | 0.6 | E | -71.4 | -2.6 | 59.0 | 0.421 | 0.179 |
A:O60341:0.179 |
FAD |
9.969 |
HG22 |
H61A |
|
| 6wc6 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-30 | THR | A:440 | A:610 | 83.0 | 0.593 | T | -77.6 | -5.3 | 38.0 | 0.271 | 0.322 |
C:O60341:0.321 |
|||||
| 2h94 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2006-07-04 | THR | A:439 | A:610 | 144.0 | 1.0 | S | -36.0 | 69.3 | 144.0 | 1.0 | 0.0 | ||||||
| 2hko | 1 | O60341 | 99.25 | 0.0 |
X-RAY |
2006-08-29 | THR | A:439 | A:610 | 101.0 | 0.721 | E | -58.3 | -15.6 | 101.0 | 0.721 | 0.0 |
HOH |
8.192 |
N |
O |
||
| 7e0g | 1 | O60341 | 99.1 | 0.0 |
X-RAY |
2021-03-24 | THR | A:442 | A:610 | 111.0 | 0.793 | T | -63.5 | -1.3 | 111.0 | 0.793 | 0.0 |
HOH |
4.744 |
CG2 |
O |
||
| 6s35 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-02-26 | THR | A:443 | A:610 | 75.0 | 0.536 | S | -93.4 | -16.3 | 75.0 | 0.536 | 0.0 | ||||||
| 5h6q | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | THR | A:446 | A:610 | 82.0 | 0.586 | T | -68.1 | -9.7 | 82.0 | 0.586 | 0.0 | ||||||
| 5h6r | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | THR | A:446 | A:610 | 83.0 | 0.593 | T | -69.5 | -15.9 | 83.0 | 0.593 | 0.0 |
HOH |
6.959 |
O |
O |
||
| 5x60 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | THR | A:446 | A:610 | 87.0 | 0.621 | T | -65.6 | -17.0 | 87.0 | 0.621 | 0.0 |
HOH |
9.838 |
CG2 |
O |
||
| 5yjb | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2018-07-04 | THR | A:446 | A:610 | 82.0 | 0.586 | T | -64.7 | -2.5 | 82.0 | 0.586 | 0.0 | ||||||
| 6kgk | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | THR | A:446 | A:610 | 82.0 | 0.586 | T | -59.3 | -6.6 | 82.0 | 0.586 | 0.0 | ||||||
| 6kgl | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | THR | A:446 | A:610 | 83.0 | 0.593 | T | -58.8 | -8.8 | 83.0 | 0.593 | 0.0 | ||||||
| 6kgm | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | THR | A:446 | A:610 | 76.0 | 0.543 | T | -62.1 | -10.9 | 76.0 | 0.543 | 0.0 | ||||||
| 6kgn | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | THR | A:446 | A:610 | 75.0 | 0.536 | T | -61.0 | -11.8 | 75.0 | 0.536 | 0.0 | ||||||
| 6kgo | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | THR | A:446 | A:610 | 102.0 | 0.729 | E | -63.1 | 1.9 | 102.0 | 0.729 | 0.0 |
HOH |
5.336 |
CG2 |
O |
||
| 6kgp | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | THR | A:446 | A:610 | 102.0 | 0.729 | E | -63.1 | 2.4 | 102.0 | 0.729 | 0.0 |
HOH |
5.276 |
CG2 |
O |
||
| 6kgq | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | THR | A:446 | A:610 | 116.0 | 0.829 | T | -52.9 | -18.8 | 116.0 | 0.829 | 0.0 | ||||||
| 6kgr | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | THR | A:446 | A:610 | 116.0 | 0.829 | T | -52.9 | -18.7 | 116.0 | 0.829 | 0.0 | ||||||
| 7cdc | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | THR | A:446 | A:610 | 86.0 | 0.614 | T | -67.4 | -12.4 | 86.0 | 0.614 | 0.0 |
HOH |
8.761 |
N |
O |
||
| 7cdd | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | THR | A:446 | A:610 | 85.0 | 0.607 | T | -63.3 | -12.0 | 85.0 | 0.607 | 0.0 |
HOH |
8.944 |
N |
O |
||
| 7cde | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | THR | A:446 | A:610 | 89.0 | 0.636 | T | -59.6 | -20.8 | 89.0 | 0.636 | 0.0 | ||||||
| 7cdf | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | THR | A:446 | A:610 | 80.0 | 0.571 | T | -68.5 | -13.8 | 80.0 | 0.571 | 0.0 | ||||||
| 7cdg | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | THR | A:446 | A:610 | 82.0 | 0.586 | T | -71.5 | -5.9 | 82.0 | 0.586 | 0.0 |
HOH |
8.471 |
N |
O |
||
| 2ejr | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-01-01 | THR | A:439 | A:610 | 109.0 | 0.779 | T | -51.1 | -3.9 | 109.0 | 0.779 | 0.0 |
HOH |
3.982 |
CG2 |
O |
||
| 2z3y | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-01-01 | THR | A:439 | A:610 | 110.0 | 0.786 | T | -54.2 | 0.5 | 110.0 | 0.786 | 0.0 |
HOH |
4.085 |
CG2 |
O |
||
| 2z5u | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-04-01 | THR | A:439 | A:610 | 111.0 | 0.793 | T | -52.2 | -0.3 | 111.0 | 0.793 | 0.0 |
HOH |
3.953 |
CG2 |
O |
||
| 3abt | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2010-07-07 | THR | A:439 | A:610 | 108.0 | 0.771 | T | -56.2 | -1.8 | 108.0 | 0.771 | 0.0 | ||||||
| 3abu | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2010-07-07 | THR | A:439 | A:610 | 114.0 | 0.814 | T | -44.7 | -3.5 | 114.0 | 0.814 | 0.0 | ||||||
| 6k3e | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-05-20 | THR | A:439 | A:610 | 84.0 | 0.6 | T | -56.8 | -30.0 | 84.0 | 0.6 | 0.0 | ||||||
| 2dw4 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-09-04 | THR | A:439 | A:610 | 111.0 | 0.793 | T | -53.3 | 3.7 | 111.0 | 0.793 | 0.0 |
HOH |
5.403 |
CG2 |
O |
||
| 6w4k | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-10-21 | THR | A:437 | A:610 | 92.0 | 0.657 | T | -14.5 | -50.2 | 92.0 | 0.657 | 0.0 | ||||||
| 6nqm | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-02-13 | THR | A:438 | A:610 | 97.0 | 0.693 | T | -64.0 | -25.4 | 97.0 | 0.693 | 0.0 | ||||||
| 6nqu | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-02-13 | THR | A:438 | A:610 | 74.0 | 0.529 | T | -22.6 | -30.7 | 74.0 | 0.529 | 0.0 | ||||||
| 6nr5 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-07-17 | THR | A:438 | A:610 | 74.0 | 0.529 | T | -73.7 | 29.1 | 74.0 | 0.529 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o60341-f1 | 1 | O60341 | 94.98 | 0.0 | THR | A:610 | A:610 | 90.0 | 0.643 | E | -69.1 | -9.4 | |