Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23408767 . T A CCDS30627.1:NM_015013.3:c.2281Tat>Aat_NP_055828.2:p.761Y>N Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
2013-06-12 TYR A:781 A:761 46.0 0.2 -166.7 168.9 24.0 0.104 0.096 C:None:0.096
FAD
3.387
CD2
C9
3zmv 1 O60341 99.54 0.0 X-RAY
2013-06-12 TYR A:781 A:761 46.0 0.2 -160.7 163.9 23.0 0.1 0.1 C:None:0.1
FAD
3.516
CD2
C9
3zms 1 O60341 99.43 0.0 X-RAY
2013-06-12 TYR A:781 A:761 47.0 0.204 -152.3 168.3 28.0 0.122 0.082 C:Q01101:0.083
FAD
3.284
CD2
C9
3zmt 1 O60341 99.43 0.0 X-RAY
2013-06-12 TYR A:781 A:761 45.0 0.196 -158.4 170.2 25.0 0.109 0.087 C:None:0.087
FAD
3.298
CD2
C9
3zmz 1 O60341 99.43 0.0 X-RAY
2013-06-12 TYR A:781 A:761 47.0 0.204 -162.8 163.0 24.0 0.104 0.1 C:None:0.1
FAD
3.342
CD2
C9
3zn0 1 O60341 99.43 0.0 X-RAY
2013-06-12 TYR A:781 A:761 48.0 0.209 -166.2 160.6 27.0 0.117 0.092 C:None:0.091
FAD
3.209
CD2
C9
3zn1 1 O60341 99.43 0.0 X-RAY
2013-06-12 TYR A:781 A:761 48.0 0.209 -150.7 176.9 28.0 0.122 0.087 C:None:0.087
FAD
3.397
CD2
C9
4czz 1 O60341 99.43 0.0 X-RAY
2014-06-11 TYR A:781 A:761 50.0 0.217 -158.4 167.1 50.0 0.217 0.0 FAD
3.420
CD2
C9
4uv8 1 O60341 99.43 0.0 X-RAY
2014-09-10 TYR A:781 A:761 48.0 0.209 -167.2 164.2 48.0 0.209 0.0 D69
HOH
3.131
6.460
CZ
OH
NAA
O
4uv9 1 O60341 99.43 0.0 X-RAY
2014-09-10 TYR A:781 A:761 43.0 0.187 -161.2 165.4 43.0 0.187 0.0 D70
2.923
CZ
NAA
4uva 1 O60341 99.43 0.0 X-RAY
2014-09-10 TYR A:781 A:761 47.0 0.204 -166.0 163.2 47.0 0.204 0.0 D73
HOH
3.069
6.294
CZ
OH
NAA
O
4uvb 1 O60341 99.43 0.0 X-RAY
2014-09-10 TYR A:781 A:761 46.0 0.2 -165.1 164.7 46.0 0.2 0.0 D51
3.134
OH
CAI
4uvc 1 O60341 99.43 0.0 X-RAY
2014-09-10 TYR A:781 A:761 55.0 0.239 -140.9 176.6 55.0 0.239 0.0 D52
2.932
CE2
NAA
6tuy 1 O60341 94.98 0.0 X-RAY
2021-07-21 TYR A:761 A:761 49.0 0.213 -174.8 162.6 49.0 0.213 0.0 FAD
NY8
NY8
HOH
3.515
3.878
3.882
9.176
CD2
OH
OH
N
C9
CAH
CAE
O
2xaf 1 O60341 94.98 0.0 X-RAY
2010-05-05 TYR A:761 A:761 46.0 0.2 -174.1 162.9 46.0 0.2 0.0 FAD
TCF
3.410
3.498
CD2
OH
C9
C3B
2xag 1 O60341 94.98 0.0 X-RAY
2010-05-05 TYR A:761 A:761 44.0 0.191 -179.5 162.0 44.0 0.191 0.0 FAD
TCF
3.250
3.344
CD2
OH
C9
C3B
2xah 1 O60341 94.98 0.0 X-RAY
2010-05-05 TYR A:761 A:761 42.0 0.183 E -160.1 178.0 42.0 0.183 0.0 FAD
3PL
3.273
2.866
CD2
OH
C9
O
2xaj 1 O60341 94.98 0.0 X-RAY
2010-05-05 TYR A:761 A:761 48.0 0.209 -174.8 162.9 48.0 0.209 0.0 FAD
TCA
3.210
3.264
CD2
OH
C9
C3
2xaq 1 O60341 94.98 0.0 X-RAY
2010-05-05 TYR A:761 A:761 56.0 0.243 -178.0 117.1 56.0 0.243 0.0 FAD
M84
3.522
3.617
CD2
OH
C9
C3B
2xas 1 O60341 94.98 0.0 X-RAY
2010-05-05 TYR A:761 A:761 46.0 0.2 -172.3 164.3 46.0 0.2 0.0 FAD
M80
3.332
3.328
CD2
CE2
C9
C3B
4uxn 1 O60341 94.98 0.0 X-RAY
2015-02-25 TYR A:761 A:761 15.0 0.065 -160.9 165.6 15.0 0.065 0.0 FAD
M8A
3.506
3.359
CD1
OH
C9
CAK
5lhg 1 O60341 94.98 0.0 X-RAY
2017-02-22 TYR A:761 A:761 49.0 0.213 -154.6 -177.8 49.0 0.213 0.0 FAD
GOL
6X3
6X3
HOH
3.462
9.548
3.450
3.882
5.802
CD2
O
OH
CE1
CA
C9
C2
C01
C01
O
5lhh 1 O60341 94.98 0.0 X-RAY
2017-02-22 TYR A:761 A:761 50.0 0.217 -159.5 175.9 50.0 0.217 0.0 FAD
GOL
GOL
6X0
HOH
3.465
7.583
9.600
3.229
3.591
CD2
O
OH
OH
CE1
C9
O3
O3
C01
O
5lhi 1 O60341 94.98 0.0 X-RAY
2017-02-22 TYR A:761 A:761 56.0 0.243 -145.4 179.0 56.0 0.243 0.0 FAD
6X5
HOH
3.517
3.393
5.827
CD2
CE2
CA
C9
C35
O
6te1 1 O60341 94.98 0.0 X-RAY
2020-06-03 TYR A:761 A:761 55.0 0.239 -155.3 179.4 55.0 0.239 0.0 N4K
N4K
FAD
GOL
HOH
8.425
3.830
3.317
9.648
5.953
OH
OH
CD2
O
CA
C25
C01
C9
C1
O
5l3c 1 O60341 94.86 0.0 X-RAY
2016-05-04 TYR A:761 A:761 56.0 0.243 -157.3 173.3 56.0 0.243 0.0 FAD
3.387
CD2
C9
5l3d 1 O60341 94.86 0.0 X-RAY
2016-05-04 HIS A:761 A:761 54.0 0.277 -137.1 147.4 54.0 0.277 0.0 FAD
HOH
3.351
6.727
NE2
O
C9A
O
5l3b 1 O60341 94.86 0.0 X-RAY
2016-05-04 TYR A:761 A:761 54.0 0.235 -158.5 172.1 54.0 0.235 0.0 FAD
3.385
CD2
C9
2x0l 1 O60341 100.0 0.0 X-RAY
2010-03-02 TYR A:643 A:761 44.0 0.191 -159.1 170.1 24.0 0.104 0.087 C:Q5TEC6:0.087
FAD
3.245
CD2
C9
4bay 1 O60341 99.85 0.0 X-RAY
2013-11-27 TYR A:595 A:761 50.0 0.217 -164.4 172.1 50.0 0.217 0.0 FAD
3.473
CD2
C9
2v1d 1 O60341 99.42 0.0 X-RAY
2007-05-29 TYR A:639 A:761 46.0 0.2 -164.8 170.4 27.0 0.117 0.083 C:Q16695:0.083
FAD
3.336
CD2
C9
2y48 1 O60341 99.42 0.0 X-RAY
2011-02-16 TYR A:639 A:761 46.0 0.2 -162.6 172.8 25.0 0.109 0.091 C:O95863:0.091
FAD
3.240
CD2
C9
5l3e 1 O60341 99.42 0.0 X-RAY
2016-09-21 TYR A:639 A:761 47.0 0.204 -167.1 164.1 47.0 0.204 0.0 FAD
E11
3.386
4.422
CD2
CE1
C9
CAS
5l3f 1 O60341 99.42 0.0 X-RAY
2016-09-21 TYR A:639 A:761 48.0 0.209 -158.1 -174.3 46.0 0.2 0.009 C:None:0.009
FAD
3.298
CD2
C9
5l3g 1 O60341 99.42 0.0 X-RAY
2016-09-21 TYR A:639 A:761 53.0 0.23 -164.4 164.0 42.0 0.183 0.047 C:None:0.048
FAD
3.487
CD2
C9
5lbq 1 O60341 99.42 0.0 X-RAY
2016-09-21 TYR A:639 A:761 58.0 0.252 -160.0 -177.8 58.0 0.252 0.0 FAD
767
767
3.310
4.639
9.763
CD2
CE1
OH
C9
C2
C26
5lgt 1 O60341 99.42 0.0 X-RAY
2017-02-22 TYR A:639 A:761 51.0 0.222 -163.1 165.6 51.0 0.222 0.0 FAD
6W3
3.438
3.296
CD2
OH
C9
CAB
5lgu 1 O60341 99.42 0.0 X-RAY
2017-02-22 TYR A:639 A:761 52.0 0.226 -165.9 168.1 52.0 0.226 0.0 FAD
6W1
3.550
3.430
CD2
OH
C9
C
6vyp 7 O60341 98.69 0.0 X-RAY
2020-05-27 TYR S:593 M:761 48.0 0.209 -163.1 161.0 26.0 0.113 0.096 E:A0A310TTQ1:0.096
FAD
3.618
CD2
C9
TYR U:593 m:761 43.0 0.187 -163.3 160.5 NA NA NA
TYR W:593 K:761 49.0 0.213 -155.6 163.9 26.0 0.113 0.1 A:A0A310TTQ1:0.1
FAD
3.644
CB
C8M
TYR Y:593 k:761 52.0 0.226 -139.5 152.0 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
2017-02-22 TYR A:595 A:765 55.0 0.239 -166.4 175.3 55.0 0.239 0.0 FAD
6W0
3.360
3.424
CD2
OH
C9
CAB
2iw5 1 O60341 99.4 0.0 X-RAY
2006-08-09 TYR A:591 A:761 48.0 0.209 -162.2 161.0 48.0 0.209 0.0 FAD
HOH
3.444
3.871
CD2
CE1
C9
O
2uxn 1 O60341 99.4 0.0 X-RAY
2007-05-29 TYR A:591 A:761 45.0 0.196 -164.3 159.6 18.0 0.078 0.118 C:P68431:0.117
FDA
HOH
3.502
5.544
CD2
CA
C9
O
2uxx 1 O60341 99.4 0.0 X-RAY
2007-08-21 TYR A:591 A:761 51.0 0.222 -160.1 166.3 51.0 0.222 0.0 FAJ
HOH
3.348
8.652
OH
CA
C12
O
4kum 1 O60341 99.4 0.0 X-RAY
2014-05-07 TYR A:591 A:761 50.0 0.217 -168.0 164.2 50.0 0.217 0.0 FAD
THG
HOH
3.383
3.369
8.667
CD2
OH
CA
C9
N10
O
4xbf 1 O60341 99.4 0.0 X-RAY
2016-04-27 TYR A:591 A:761 50.0 0.217 -165.1 172.6 50.0 0.217 0.0 FAD
HOH
2.392
4.566
HD2
HA
H9
O
6wc6 1 O60341 99.4 0.0 X-RAY
2021-06-30 TYR A:591 A:761 51.0 0.222 -158.0 173.1 51.0 0.222 0.0 FAD
3.399
CD2
C9
2h94 1 O60341 99.4 0.0 X-RAY
2006-07-04 TYR A:590 A:761 52.0 0.226 -155.2 173.3 52.0 0.226 0.0 FAD
HOH
3.430
5.076
CD2
CA
C9
O
2hko 1 O60341 99.25 0.0 X-RAY
2006-08-29 TYR A:590 A:761 51.0 0.222 -161.2 176.4 51.0 0.222 0.0 FAD
HOH
3.563
3.492
CD2
CE1
C9
O
7e0g 1 O60341 99.1 0.0 X-RAY
2021-03-24 TYR A:593 A:761 50.0 0.217 -169.3 164.1 50.0 0.217 0.0 HUF
IMD
HOH
3.442
6.446
3.680
CD1
OH
CE2
C13
N3
O
6s35 1 O60341 99.4 0.0 X-RAY
2020-02-26 TYR A:594 A:761 55.0 0.239 -166.0 162.5 55.0 0.239 0.0 FAD
3.277
CD2
C9
5h6q 1 O60341 99.4 0.0 X-RAY
2017-04-12 TYR A:597 A:761 42.0 0.183 -164.1 168.9 25.0 0.109 0.074 C:None:0.074
FAD
HOH
3.456
5.712
CD2
CA
C9
O
5h6r 1 O60341 99.4 0.0 X-RAY
2017-04-12 TYR A:597 A:761 45.0 0.196 -159.5 163.9 24.0 0.104 0.092 C:None:0.091
FAD
HOH
3.469
5.746
CD2
CA
C9
O
5x60 1 O60341 99.4 0.0 X-RAY
2017-04-12 TYR A:597 A:761 43.0 0.187 -162.7 168.6 24.0 0.104 0.083 C:None:0.083
FAD
HOH
3.418
5.669
CD2
CA
C9
O
5yjb 1 O60341 99.4 0.0 X-RAY
2018-07-04 TYR A:597 A:761 52.0 0.226 -150.0 169.1 52.0 0.226 0.0 FAD
8WC
3.350
3.463
CD2
OH
C9
C10
6kgk 1 O60341 99.4 0.0 X-RAY
2020-03-25 TYR A:597 A:761 44.0 0.191 -168.6 168.2 44.0 0.191 0.0 GOL
DJ0
FAD
HOH
9.355
3.859
3.479
5.695
OH
CZ
CD1
CA
O2
C35
C9
O
6kgl 1 O60341 99.4 0.0 X-RAY
2020-03-25 TYR A:597 A:761 43.0 0.187 -167.9 167.2 43.0 0.187 0.0 GOL
DJ0
FAD
HOH
9.411
3.277
3.389
5.695
OH
OH
CD1
CA
O2
C29
C9
O
6kgm 1 O60341 99.4 0.0 X-RAY
2020-03-25 TYR A:597 A:761 46.0 0.2 -168.1 165.5 46.0 0.2 0.0 GOL
DJ0
FAD
HOH
9.704
3.869
3.497
5.718
OH
CZ
CD1
CA
C2
C35
C9
O
6kgn 1 O60341 99.4 0.0 X-RAY
2020-03-25 TYR A:597 A:761 46.0 0.2 -168.3 165.6 46.0 0.2 0.0 GOL
DJ0
FAD
HOH
9.712
3.234
3.429
5.708
OH
OH
CD1
CA
C2
C29
C9
O
6kgo 1 O60341 99.4 0.0 X-RAY
2020-03-25 TYR A:597 A:761 44.0 0.191 -167.7 159.6 44.0 0.191 0.0 DJ0
FAD
HOH
3.871
3.553
3.732
CZ
CD2
CD1
C35
C9
O
6kgp 1 O60341 99.4 0.0 X-RAY
2020-03-25 TYR A:597 A:761 44.0 0.191 -168.1 159.6 44.0 0.191 0.0 DJ0
FAD
HOH
3.259
3.484
3.745
OH
CD2
CD1
C29
C9
O
6kgq 1 O60341 99.4 0.0 X-RAY
2020-03-25 TYR A:597 A:761 42.0 0.183 -164.3 163.2 42.0 0.183 0.0 MPD
DJC
FAD
HOH
8.551
3.530
3.608
3.734
OH
OH
CE1
CD2
C1
C28
C9A
O
6kgr 1 O60341 99.4 0.0 X-RAY
2020-03-25 TYR A:597 A:761 42.0 0.183 -165.1 162.6 42.0 0.183 0.0 MPD
DJC
FAD
HOH
8.541
3.258
3.631
3.740
OH
OH
CD1
CD2
C1
C29
C9A
O
7cdc 1 O60341 99.4 0.0 X-RAY
2021-06-23 TYR A:597 A:761 44.0 0.191 -161.7 164.6 25.0 0.109 0.082 C:None:0.083
FAD
HOH
3.361
5.728
CD2
CA
C9
O
7cdd 1 O60341 99.4 0.0 X-RAY
2021-06-23 TYR A:597 A:761 46.0 0.2 -162.4 165.8 25.0 0.109 0.091 C:None:0.091
FAD
HOH
3.337
7.394
CD2
O
C9
O
7cde 1 O60341 99.4 0.0 X-RAY
2021-06-23 TYR A:597 A:761 43.0 0.187 -164.8 165.9 22.0 0.096 0.091 C:None:0.091
FAD
GOL
HOH
3.296
9.712
6.998
CD2
OH
O
C9
O3
O
7cdf 1 O60341 99.4 0.0 X-RAY
2021-06-23 TYR A:597 A:761 48.0 0.209 -164.1 166.0 28.0 0.122 0.087 C:None:0.087
FAD
HOH
3.239
7.428
CD2
O
C9
O
7cdg 1 O60341 99.4 0.0 X-RAY
2021-06-23 TYR A:597 A:761 46.0 0.2 -163.7 163.7 26.0 0.113 0.087 C:None:0.087
FAD
3.270
CD2
C9
2ejr 1 O60341 99.4 0.0 X-RAY
2008-01-01 TYR A:590 A:761 44.0 0.191 -165.6 164.3 44.0 0.191 0.0 F2N
HOH
3.308
3.810
CD1
CD2
CBK
O
2z3y 1 O60341 99.4 0.0 X-RAY
2008-01-01 TYR A:590 A:761 44.0 0.191 -164.7 161.3 44.0 0.191 0.0 F2N
HOH
3.393
3.790
CD1
CD2
CBK
O
2z5u 1 O60341 99.4 0.0 X-RAY
2008-04-01 TYR A:590 A:761 45.0 0.196 -167.1 159.8 45.0 0.196 0.0 FAJ
HOH
3.501
3.813
CD1
CD2
C20
O
3abt 1 O60341 99.4 0.0 X-RAY
2010-07-07 TYR A:590 A:761 49.0 0.213 -165.1 156.6 49.0 0.213 0.0 2PF
3.287
CZ
FAA
3abu 1 O60341 99.4 0.0 X-RAY
2010-07-07 TYR A:590 A:761 45.0 0.196 -167.7 162.4 45.0 0.196 0.0 12F
3.233
CZ
CAL
6k3e 1 O60341 99.4 0.0 X-RAY
2020-05-20 TYR A:590 A:761 49.0 0.213 -170.2 169.1 49.0 0.213 0.0 CW0
D3U
CVO
HOH
4.501
3.477
5.383
8.369
CE1
CD2
CE1
CA
C6
CAB
C5
O
2dw4 1 O60341 99.4 0.0 X-RAY
2007-09-04 TYR A:590 A:761 52.0 0.226 -169.4 161.3 52.0 0.226 0.0 FAD
HOH
3.439
3.503
CD1
OH
C9
O
6w4k 1 O60341 99.4 0.0 X-RAY
2020-10-21 TYR A:588 A:761 47.0 0.204 -170.6 168.8 47.0 0.204 0.0 V0Y
FAD
HOH
3.322
3.324
3.676
OH
CD2
CE1
C9
C9
O
6nqm 1 O60341 99.4 0.0 X-RAY
2019-02-13 TYR A:589 A:761 51.0 0.222 -163.4 161.9 51.0 0.222 0.0 FAD
2.049
HD2
H9
6nqu 1 O60341 99.4 0.0 X-RAY
2019-02-13 TYR A:589 A:761 46.0 0.2 -159.0 172.7 46.0 0.2 0.0 KWM
3.448
CD2
C20
6nr5 1 O60341 99.4 0.0 X-RAY
2019-07-17 TYR A:589 A:761 44.0 0.191 -137.4 168.2 44.0 0.191 0.0 KXM
3.729
CD2
C3

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 TYR A:761 A:761 23.0 0.1 -153.3 165.7