Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23408818 . C A CCDS30627.1:NM_015013.3:c.2332Cag>Aag_NP_055828.2:p.778Q>K Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
 2013-06-12 GLN A:798 A:778 97.0 0.539 S -61.0 126.5 97.0 0.539 0.0
3zmv 1 O60341 99.54 0.0 X-RAY
 2013-06-12 GLN A:798 A:778 102.0 0.567 S -48.7 123.8 102.0 0.567 0.0
3zms 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLN A:798 A:778 94.0 0.522 -65.7 123.3 94.0 0.522 0.0
3zmt 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLN A:798 A:778 99.0 0.55 S -66.4 127.2 99.0 0.55 0.0
3zmz 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLN A:798 A:778 96.0 0.533 -61.2 121.4 96.0 0.533 0.0
3zn0 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLN A:798 A:778 98.0 0.544 -62.9 126.4 98.0 0.544 0.0
3zn1 1 O60341 99.43 0.0 X-RAY
 2013-06-12 GLN A:798 A:778 100.0 0.556 S -64.2 117.1 100.0 0.556 0.0
4czz 1 O60341 99.43 0.0 X-RAY
 2014-06-11 GLN A:798 A:778 94.0 0.522 -58.3 116.6 94.0 0.522 0.0
4uv8 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLN A:798 A:778 96.0 0.533 -61.2 125.9 96.0 0.533 0.0
4uv9 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLN A:798 A:778 95.0 0.528 -57.6 123.1 95.0 0.528 0.0
4uva 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLN A:798 A:778 94.0 0.522 -65.0 127.7 94.0 0.522 0.0
4uvb 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLN A:798 A:778 95.0 0.528 -65.9 126.3 95.0 0.528 0.0
4uvc 1 O60341 99.43 0.0 X-RAY
 2014-09-10 GLN A:798 A:778 103.0 0.572 S -50.5 120.1 103.0 0.572 0.0
6tuy 1 O60341 94.98 0.0 X-RAY
 2021-07-21 GLN A:778 A:778 106.0 0.589 -67.7 128.5 106.0 0.589 0.0 HOH
 3.608
 OE1
 O
2xaf 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:778 A:778 99.0 0.55 -57.6 115.5 99.0 0.55 0.0
2xag 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:778 A:778 101.0 0.561 S -53.2 118.8 101.0 0.561 0.0
2xah 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:778 A:778 102.0 0.567 S -55.9 120.4 102.0 0.567 0.0
2xaj 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:778 A:778 101.0 0.561 -53.9 117.2 101.0 0.561 0.0
2xaq 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:778 A:778 96.0 0.533 -40.0 129.7 96.0 0.533 0.0
2xas 1 O60341 94.98 0.0 X-RAY
 2010-05-05 GLN A:778 A:778 92.0 0.511 -52.2 119.4 92.0 0.511 0.0
4uxn 1 O60341 94.98 0.0 X-RAY
 2015-02-25 GLN A:778 A:778 96.0 0.533 S -60.6 123.1 96.0 0.533 0.0
5lhg 1 O60341 94.98 0.0 X-RAY
 2017-02-22 GLN A:778 A:778 95.0 0.528 S -62.5 121.0 95.0 0.528 0.0 GOL
 4.117
 CG
 O2
5lhh 1 O60341 94.98 0.0 X-RAY
 2017-02-22 GLN A:778 A:778 97.0 0.539 S -67.9 132.9 97.0 0.539 0.0 GOL
HOH
 4.031
3.996
 CG
C
 O3
O
5lhi 1 O60341 94.98 0.0 X-RAY
 2017-02-22 GLN A:778 A:778 90.0 0.5 S -69.5 118.7 90.0 0.5 0.0 HOH
 6.715
 CG
 O
6te1 1 O60341 94.98 0.0 X-RAY
 2020-06-03 GLN A:778 A:778 95.0 0.528 S -63.1 130.4 95.0 0.528 0.0 GOL
 3.916
 CG
 C3
5l3c 1 O60341 94.86 0.0 X-RAY
 2016-05-04 GLN A:778 A:778 100.0 0.556 -57.8 115.4 100.0 0.556 0.0
5l3d 1 O60341 94.86 0.0 X-RAY
 2016-05-04 GLN A:778 A:778 94.0 0.522 -75.6 130.4 94.0 0.522 0.0 HOH
 2.752
 NE2
 O
5l3b 1 O60341 94.86 0.0 X-RAY
 2016-05-04 GLN A:778 A:778 102.0 0.567 -58.4 117.3 102.0 0.567 0.0
2x0l 1 O60341 100.0 0.0 X-RAY
 2010-03-02 GLN A:660 A:778 95.0 0.528 -65.4 116.6 95.0 0.528 0.0
4bay 1 O60341 99.85 0.0 X-RAY
 2013-11-27 GLN A:612 A:778 98.0 0.544 -50.7 121.7 98.0 0.544 0.0
2v1d 1 O60341 99.42 0.0 X-RAY
 2007-05-29 GLN A:656 A:778 94.0 0.522 S -58.0 113.9 94.0 0.522 0.0
2y48 1 O60341 99.42 0.0 X-RAY
 2011-02-16 GLN A:656 A:778 98.0 0.544 S -62.6 124.4 98.0 0.544 0.0
5l3e 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLN A:656 A:778 103.0 0.572 -65.2 127.9 103.0 0.572 0.0
5l3f 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLN A:656 A:778 103.0 0.572 -55.9 116.7 103.0 0.572 0.0
5l3g 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLN A:656 A:778 103.0 0.572 -68.4 122.1 103.0 0.572 0.0
5lbq 1 O60341 99.42 0.0 X-RAY
 2016-09-21 GLN A:656 A:778 105.0 0.583 -54.1 110.6 105.0 0.583 0.0
5lgt 1 O60341 99.42 0.0 X-RAY
 2017-02-22 GLN A:656 A:778 95.0 0.528 -61.9 125.7 95.0 0.528 0.0
5lgu 1 O60341 99.42 0.0 X-RAY
 2017-02-22 GLN A:656 A:778 97.0 0.539 S -50.7 124.4 97.0 0.539 0.0
6vyp 7 O60341 98.69 0.0 X-RAY
 2020-05-27 GLN S:610 M:778 90.0 0.5 S -70.3 134.8 90.0 0.5 0.0
GLN U:610 m:778 99.0 0.55 S -70.0 134.8 NA NA NA
GLN W:610 K:778 88.0 0.489 S -73.0 129.5 88.0 0.489 0.0
GLN Y:610 k:778 88.0 0.489 S -77.1 135.7 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
 2017-02-22 GLN A:612 A:782 97.0 0.539 -52.3 121.7 97.0 0.539 0.0
2iw5 1 O60341 99.4 0.0 X-RAY
 2006-08-09 GLN A:608 A:778 81.0 0.45 -65.8 122.7 81.0 0.45 0.0 HOH
 3.928
 C
 O
2uxn 1 O60341 99.4 0.0 X-RAY
 2007-05-29 GLN A:608 A:778 81.0 0.45 -61.9 133.2 81.0 0.45 0.0 CL
HOH
 5.199
3.651
 CG
C
 CL
O
2uxx 1 O60341 99.4 0.0 X-RAY
 2007-08-21 GLN A:608 A:778 91.0 0.506 -63.3 125.9 91.0 0.506 0.0 HOH
 6.944
 O
 O
4kum 1 O60341 99.4 0.0 X-RAY
 2014-05-07 GLN A:608 A:778 103.0 0.572 -63.4 119.1 103.0 0.572 0.0
4xbf 1 O60341 99.4 0.0 X-RAY
 2016-04-27 GLN A:608 A:778 101.0 0.561 -70.3 125.1 64.0 0.356 0.205 A:O60341:0.206
 HOH
 3.869
 C
 O
6wc6 1 O60341 99.4 0.0 X-RAY
 2021-06-30 GLN A:608 A:778 108.0 0.6 -64.4 118.5 108.0 0.6 0.0
2h94 1 O60341 99.4 0.0 X-RAY
 2006-07-04 GLN A:607 A:778 88.0 0.489 -41.7 122.1 88.0 0.489 0.0
2hko 1 O60341 99.25 0.0 X-RAY
 2006-08-29 GLN A:607 A:778 98.0 0.544 S -56.1 130.0 98.0 0.544 0.0 HOH
 3.693
 OE1
 O
7e0g 1 O60341 99.1 0.0 X-RAY
 2021-03-24 GLN A:610 A:778 90.0 0.5 -64.8 124.9 90.0 0.5 0.0 HOH
 3.981
 C
 O
6s35 1 O60341 99.4 0.0 X-RAY
 2020-02-26 GLN A:611 A:778 103.0 0.572 S -64.7 121.5 103.0 0.572 0.0
5h6q 1 O60341 99.4 0.0 X-RAY
 2017-04-12 GLN A:614 A:778 86.0 0.478 -74.0 132.5 86.0 0.478 0.0 HOH
 3.614
 OE1
 O
5h6r 1 O60341 99.4 0.0 X-RAY
 2017-04-12 GLN A:614 A:778 93.0 0.517 -70.2 128.1 93.0 0.517 0.0 HOH
 3.240
 OE1
 O
5x60 1 O60341 99.4 0.0 X-RAY
 2017-04-12 GLN A:614 A:778 91.0 0.506 S -74.0 127.3 91.0 0.506 0.0 HOH
 3.057
 OE1
 O
5yjb 1 O60341 99.4 0.0 X-RAY
 2018-07-04 GLN A:614 A:778 100.0 0.556 S -65.6 122.6 100.0 0.556 0.0
6kgk 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:614 A:778 96.0 0.533 S -67.4 129.0 96.0 0.533 0.0 HOH
 3.378
 NE2
 O
6kgl 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:614 A:778 96.0 0.533 S -67.0 127.8 96.0 0.533 0.0 HOH
 3.337
 NE2
 O
6kgm 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:614 A:778 93.0 0.517 -70.6 128.8 93.0 0.517 0.0 HOH
 2.987
 NE2
 O
6kgn 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:614 A:778 94.0 0.522 -70.3 128.8 94.0 0.522 0.0 HOH
 2.972
 NE2
 O
6kgo 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:614 A:778 92.0 0.511 -72.0 128.2 92.0 0.511 0.0 HOH
 3.895
 C
 O
6kgp 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:614 A:778 93.0 0.517 -72.3 128.3 93.0 0.517 0.0 HOH
 3.910
 C
 O
6kgq 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:614 A:778 88.0 0.489 -66.1 126.7 88.0 0.489 0.0 HOH
 3.960
 C
 O
6kgr 1 O60341 99.4 0.0 X-RAY
 2020-03-25 GLN A:614 A:778 89.0 0.494 -66.4 126.7 89.0 0.494 0.0 HOH
 3.960
 C
 O
7cdc 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLN A:614 A:778 90.0 0.5 S -73.3 127.6 90.0 0.5 0.0 HOH
 2.302
 NE2
 O
7cdd 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLN A:614 A:778 94.0 0.522 S -64.8 125.3 94.0 0.522 0.0 HOH
 2.844
 OE1
 O
7cde 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLN A:614 A:778 93.0 0.517 S -64.5 129.4 93.0 0.517 0.0 HOH
 2.450
 OE1
 O
7cdf 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLN A:614 A:778 97.0 0.539 S -69.7 126.6 97.0 0.539 0.0 HOH
 2.557
 OE1
 O
7cdg 1 O60341 99.4 0.0 X-RAY
 2021-06-23 GLN A:614 A:778 98.0 0.544 S -62.4 125.0 98.0 0.544 0.0 HOH
 3.135
 CG
 O
2ejr 1 O60341 99.4 0.0 X-RAY
 2008-01-01 GLN A:607 A:778 87.0 0.483 -56.3 133.3 87.0 0.483 0.0 HOH
 3.869
 C
 O
2z3y 1 O60341 99.4 0.0 X-RAY
 2008-01-01 GLN A:607 A:778 89.0 0.494 -56.1 130.7 89.0 0.494 0.0 HOH
 3.930
 C
 O
2z5u 1 O60341 99.4 0.0 X-RAY
 2008-04-01 GLN A:607 A:778 91.0 0.506 -57.7 128.2 91.0 0.506 0.0 HOH
 4.121
 C
 O
3abt 1 O60341 99.4 0.0 X-RAY
 2010-07-07 GLN A:607 A:778 97.0 0.539 S -50.3 119.9 97.0 0.539 0.0
3abu 1 O60341 99.4 0.0 X-RAY
 2010-07-07 GLN A:607 A:778 91.0 0.506 S -57.3 118.7 91.0 0.506 0.0
6k3e 1 O60341 99.4 0.0 X-RAY
 2020-05-20 GLN A:607 A:778 101.0 0.561 S -62.8 121.0 101.0 0.561 0.0 DTT
MLA
EDO
EDO
EDO
CL
 9.386
3.154
8.142
4.436
2.633
8.984
 NE2
CG
OE1
CG
OE1
NE2
 S1
O3B
O1
O1
O2
CL
2dw4 1 O60341 99.4 0.0 X-RAY
 2007-09-04 GLN A:607 A:778 96.0 0.533 -61.4 125.5 96.0 0.533 0.0 HOH
 4.017
 C
 O
6w4k 1 O60341 99.4 0.0 X-RAY
 2020-10-21 GLN A:605 A:778 91.0 0.506 S -60.6 127.4 91.0 0.506 0.0 HOH
 3.110
 CG
 O
6nqm 1 O60341 99.4 0.0 X-RAY
 2019-02-13 GLN A:606 A:778 94.0 0.522 S -56.4 138.1 94.0 0.522 0.0
6nqu 1 O60341 99.4 0.0 X-RAY
 2019-02-13 GLN A:606 A:778 93.0 0.517 S -57.4 135.7 93.0 0.517 0.0
6nr5 1 O60341 99.4 0.0 X-RAY
 2019-07-17 GLN A:606 A:778 93.0 0.517 S -74.0 137.0 93.0 0.517 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 GLN A:778 A:778 90.0 0.5 S -69.3 130.6