Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 23408828 . C A CCDS30627.1:NM_015013.3:c.2342aCt>aAt_NP_055828.2:p.781T>N Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3zmu 1 O60341 99.54 0.0 X-RAY
 2013-06-12 THR A:801 A:781 52.0 0.371 -114.4 118.9 52.0 0.371 0.0
3zmv 1 O60341 99.54 0.0 X-RAY
 2013-06-12 THR A:801 A:781 53.0 0.379 -101.2 119.6 53.0 0.379 0.0
3zms 1 O60341 99.43 0.0 X-RAY
 2013-06-12 THR A:801 A:781 49.0 0.35 -107.6 120.2 49.0 0.35 0.0
3zmt 1 O60341 99.43 0.0 X-RAY
 2013-06-12 THR A:801 A:781 56.0 0.4 -110.4 119.5 56.0 0.4 0.0
3zmz 1 O60341 99.43 0.0 X-RAY
 2013-06-12 THR A:801 A:781 53.0 0.379 -109.6 119.7 53.0 0.379 0.0
3zn0 1 O60341 99.43 0.0 X-RAY
 2013-06-12 THR A:801 A:781 59.0 0.421 -108.4 121.2 59.0 0.421 0.0
3zn1 1 O60341 99.43 0.0 X-RAY
 2013-06-12 THR A:801 A:781 57.0 0.407 -107.1 118.1 57.0 0.407 0.0
4czz 1 O60341 99.43 0.0 X-RAY
 2014-06-11 THR A:801 A:781 52.0 0.371 -118.2 110.8 52.0 0.371 0.0
4uv8 1 O60341 99.43 0.0 X-RAY
 2014-09-10 THR A:801 A:781 52.0 0.371 -112.7 120.3 52.0 0.371 0.0
4uv9 1 O60341 99.43 0.0 X-RAY
 2014-09-10 THR A:801 A:781 53.0 0.379 -113.4 116.0 53.0 0.379 0.0
4uva 1 O60341 99.43 0.0 X-RAY
 2014-09-10 THR A:801 A:781 53.0 0.379 -110.6 120.0 53.0 0.379 0.0
4uvb 1 O60341 99.43 0.0 X-RAY
 2014-09-10 THR A:801 A:781 54.0 0.386 -109.6 121.8 54.0 0.386 0.0
4uvc 1 O60341 99.43 0.0 X-RAY
 2014-09-10 THR A:801 A:781 54.0 0.386 -104.1 122.0 54.0 0.386 0.0
6tuy 1 O60341 94.98 0.0 X-RAY
 2021-07-21 THR A:781 A:781 59.0 0.421 -123.6 107.5 59.0 0.421 0.0 CL
HOH
 4.107
8.309
 O
OG1
 CL
O
2xaf 1 O60341 94.98 0.0 X-RAY
 2010-05-05 THR A:781 A:781 51.0 0.364 -105.5 120.4 51.0 0.364 0.0
2xag 1 O60341 94.98 0.0 X-RAY
 2010-05-05 THR A:781 A:781 53.0 0.379 -117.6 111.9 53.0 0.379 0.0
2xah 1 O60341 94.98 0.0 X-RAY
 2010-05-05 THR A:781 A:781 53.0 0.379 -106.5 124.0 53.0 0.379 0.0
2xaj 1 O60341 94.98 0.0 X-RAY
 2010-05-05 THR A:781 A:781 51.0 0.364 -116.7 112.7 51.0 0.364 0.0
2xaq 1 O60341 94.98 0.0 X-RAY
 2010-05-05 THR A:781 A:781 55.0 0.393 -103.2 115.5 55.0 0.393 0.0
2xas 1 O60341 94.98 0.0 X-RAY
 2010-05-05 THR A:781 A:781 51.0 0.364 -111.5 118.2 51.0 0.364 0.0
4uxn 1 O60341 94.98 0.0 X-RAY
 2015-02-25 THR A:781 A:781 56.0 0.4 -113.8 113.1 56.0 0.4 0.0
5lhg 1 O60341 94.98 0.0 X-RAY
 2017-02-22 THR A:781 A:781 55.0 0.393 -113.1 124.3 55.0 0.393 0.0 GOL
 8.832
 N
 C3
5lhh 1 O60341 94.98 0.0 X-RAY
 2017-02-22 THR A:781 A:781 52.0 0.371 -118.4 122.1 52.0 0.371 0.0 GOL
HOH
 8.611
4.112
 N
O
 O3
O
5lhi 1 O60341 94.98 0.0 X-RAY
 2017-02-22 THR A:781 A:781 73.0 0.521 -91.6 140.5 73.0 0.521 0.0
6te1 1 O60341 94.98 0.0 X-RAY
 2020-06-03 THR A:781 A:781 55.0 0.393 -113.7 124.2 55.0 0.393 0.0 GOL
 8.956
 N
 O2
5l3c 1 O60341 94.86 0.0 X-RAY
 2016-05-04 THR A:781 A:781 54.0 0.386 -107.7 121.4 54.0 0.386 0.0
5l3d 1 O60341 94.86 0.0 X-RAY
 2016-05-04 THR A:781 A:781 53.0 0.379 -112.2 119.8 53.0 0.379 0.0 HOH
 3.136
 N
 O
5l3b 1 O60341 94.86 0.0 X-RAY
 2016-05-04 THR A:781 A:781 56.0 0.4 -109.4 118.6 56.0 0.4 0.0
2x0l 1 O60341 100.0 0.0 X-RAY
 2010-03-02 THR A:663 A:781 58.0 0.414 -116.7 116.2 58.0 0.414 0.0
4bay 1 O60341 99.85 0.0 X-RAY
 2013-11-27 THR A:615 A:781 54.0 0.386 -112.1 116.5 54.0 0.386 0.0
2v1d 1 O60341 99.42 0.0 X-RAY
 2007-05-29 THR A:659 A:781 53.0 0.379 -111.4 111.8 53.0 0.379 0.0
2y48 1 O60341 99.42 0.0 X-RAY
 2011-02-16 THR A:659 A:781 51.0 0.364 -112.6 119.0 51.0 0.364 0.0
5l3e 1 O60341 99.42 0.0 X-RAY
 2016-09-21 THR A:659 A:781 66.0 0.471 -108.7 114.7 66.0 0.471 0.0
5l3f 1 O60341 99.42 0.0 X-RAY
 2016-09-21 THR A:659 A:781 49.0 0.35 -114.2 112.5 49.0 0.35 0.0
5l3g 1 O60341 99.42 0.0 X-RAY
 2016-09-21 THR A:659 A:781 52.0 0.371 -115.0 107.6 52.0 0.371 0.0
5lbq 1 O60341 99.42 0.0 X-RAY
 2016-09-21 THR A:659 A:781 58.0 0.414 -113.7 120.6 58.0 0.414 0.0
5lgt 1 O60341 99.42 0.0 X-RAY
 2017-02-22 THR A:659 A:781 52.0 0.371 -111.5 125.4 52.0 0.371 0.0
5lgu 1 O60341 99.42 0.0 X-RAY
 2017-02-22 THR A:659 A:781 60.0 0.429 -107.8 123.5 60.0 0.429 0.0
6vyp 7 O60341 98.69 0.0 X-RAY
 2020-05-27 THR S:613 M:781 58.0 0.414 -110.0 114.3 58.0 0.414 0.0
THR U:613 m:781 60.0 0.429 -110.2 113.9 NA NA NA
THR W:613 K:781 50.0 0.357 -121.7 117.9 50.0 0.357 0.0
THR Y:613 k:781 60.0 0.429 -109.2 114.1 NA NA NA
5lgn 1 O60341 99.85 0.0 X-RAY
 2017-02-22 THR A:615 A:785 51.0 0.364 -115.6 124.8 51.0 0.364 0.0
2iw5 1 O60341 99.4 0.0 X-RAY
 2006-08-09 THR A:611 A:781 55.0 0.393 -116.9 116.0 55.0 0.393 0.0 HOH
 3.040
 N
 O
2uxn 1 O60341 99.4 0.0 X-RAY
 2007-05-29 THR A:611 A:781 55.0 0.393 -115.3 117.0 55.0 0.393 0.0 CL
HOH
 9.803
2.871
 OG1
N
 CL
O
2uxx 1 O60341 99.4 0.0 X-RAY
 2007-08-21 THR A:611 A:781 60.0 0.429 -108.0 118.4 60.0 0.429 0.0 HOH
 2.831
 N
 O
4kum 1 O60341 99.4 0.0 X-RAY
 2014-05-07 THR A:611 A:781 61.0 0.436 -117.1 119.5 61.0 0.436 0.0
4xbf 1 O60341 99.4 0.0 X-RAY
 2016-04-27 THR A:611 A:781 63.0 0.45 -110.1 107.0 63.0 0.45 0.0 U
HOH
 6.485
8.945
 O
N
 O4
O
6wc6 1 O60341 99.4 0.0 X-RAY
 2021-06-30 THR A:611 A:781 72.0 0.514 -106.0 112.9 72.0 0.514 0.0
2h94 1 O60341 99.4 0.0 X-RAY
 2006-07-04 THR A:610 A:781 69.0 0.493 -108.8 129.0 69.0 0.493 0.0
2hko 1 O60341 99.25 0.0 X-RAY
 2006-08-29 THR A:610 A:781 68.0 0.486 -92.0 138.4 68.0 0.486 0.0 HOH
 7.136
 O
 O
7e0g 1 O60341 99.1 0.0 X-RAY
 2021-03-24 THR A:613 A:781 66.0 0.471 -104.1 138.5 66.0 0.471 0.0 HOH
 2.916
 N
 O
6s35 1 O60341 99.4 0.0 X-RAY
 2020-02-26 THR A:614 A:781 58.0 0.414 -107.7 117.9 58.0 0.414 0.0
5h6q 1 O60341 99.4 0.0 X-RAY
 2017-04-12 THR A:617 A:781 57.0 0.407 -116.8 121.2 57.0 0.407 0.0 HOH
 2.727
 N
 O
5h6r 1 O60341 99.4 0.0 X-RAY
 2017-04-12 THR A:617 A:781 57.0 0.407 -108.7 121.9 57.0 0.407 0.0 HOH
 2.799
 N
 O
5x60 1 O60341 99.4 0.0 X-RAY
 2017-04-12 THR A:617 A:781 56.0 0.4 -114.7 123.4 56.0 0.4 0.0 HOH
 2.853
 N
 O
5yjb 1 O60341 99.4 0.0 X-RAY
 2018-07-04 THR A:617 A:781 62.0 0.443 -112.8 116.9 62.0 0.443 0.0
6kgk 1 O60341 99.4 0.0 X-RAY
 2020-03-25 THR A:617 A:781 54.0 0.386 -113.4 120.6 54.0 0.386 0.0 HOH
 5.288
 O
 O
6kgl 1 O60341 99.4 0.0 X-RAY
 2020-03-25 THR A:617 A:781 54.0 0.386 -113.3 121.3 54.0 0.386 0.0 HOH
 5.264
 O
 O
6kgm 1 O60341 99.4 0.0 X-RAY
 2020-03-25 THR A:617 A:781 58.0 0.414 -113.8 121.6 58.0 0.414 0.0 HOH
 5.194
 O
 O
6kgn 1 O60341 99.4 0.0 X-RAY
 2020-03-25 THR A:617 A:781 58.0 0.414 -114.2 121.7 58.0 0.414 0.0 HOH
 5.189
 O
 O
6kgo 1 O60341 99.4 0.0 X-RAY
 2020-03-25 THR A:617 A:781 61.0 0.436 -121.4 126.6 61.0 0.436 0.0 HOH
 3.069
 N
 O
6kgp 1 O60341 99.4 0.0 X-RAY
 2020-03-25 THR A:617 A:781 62.0 0.443 -121.1 126.8 62.0 0.443 0.0 HOH
 3.036
 N
 O
6kgq 1 O60341 99.4 0.0 X-RAY
 2020-03-25 THR A:617 A:781 62.0 0.443 -107.9 128.8 62.0 0.443 0.0 HOH
 2.628
 N
 O
6kgr 1 O60341 99.4 0.0 X-RAY
 2020-03-25 THR A:617 A:781 62.0 0.443 -107.5 128.7 62.0 0.443 0.0 HOH
 2.630
 N
 O
7cdc 1 O60341 99.4 0.0 X-RAY
 2021-06-23 THR A:617 A:781 56.0 0.4 -108.4 120.3 56.0 0.4 0.0 HOH
 2.769
 N
 O
7cdd 1 O60341 99.4 0.0 X-RAY
 2021-06-23 THR A:617 A:781 56.0 0.4 -104.8 120.8 56.0 0.4 0.0 HOH
 2.836
 N
 O
7cde 1 O60341 99.4 0.0 X-RAY
 2021-06-23 THR A:617 A:781 55.0 0.393 -108.2 118.4 55.0 0.393 0.0 HOH
 2.884
 N
 O
7cdf 1 O60341 99.4 0.0 X-RAY
 2021-06-23 THR A:617 A:781 54.0 0.386 -105.7 122.0 54.0 0.386 0.0 HOH
 2.904
 N
 O
7cdg 1 O60341 99.4 0.0 X-RAY
 2021-06-23 THR A:617 A:781 53.0 0.379 -108.0 120.2 53.0 0.379 0.0 HOH
 7.441
 C
 O
2ejr 1 O60341 99.4 0.0 X-RAY
 2008-01-01 THR A:610 A:781 63.0 0.45 -131.3 126.4 63.0 0.45 0.0 HOH
 2.953
 N
 O
2z3y 1 O60341 99.4 0.0 X-RAY
 2008-01-01 THR A:610 A:781 62.0 0.443 -136.7 120.9 62.0 0.443 0.0 HOH
 8.269
 CG2
 O
2z5u 1 O60341 99.4 0.0 X-RAY
 2008-04-01 THR A:610 A:781 61.0 0.436 -134.4 123.2 61.0 0.436 0.0 HOH
 8.513
 CG2
 O
3abt 1 O60341 99.4 0.0 X-RAY
 2010-07-07 THR A:610 A:781 72.0 0.514 -133.6 129.2 72.0 0.514 0.0
3abu 1 O60341 99.4 0.0 X-RAY
 2010-07-07 THR A:610 A:781 72.0 0.514 -119.8 146.8 72.0 0.514 0.0
6k3e 1 O60341 99.4 0.0 X-RAY
 2020-05-20 THR A:610 A:781 56.0 0.4 -115.4 118.3 56.0 0.4 0.0 MLA
EDO
HOH
 7.617
3.491
9.403
 OG1
OG1
CG2
 O3B
C1
O
2dw4 1 O60341 99.4 0.0 X-RAY
 2007-09-04 THR A:610 A:781 71.0 0.507 -118.7 141.2 71.0 0.507 0.0 HOH
 7.306
 C
 O
6w4k 1 O60341 99.4 0.0 X-RAY
 2020-10-21 THR A:608 A:781 58.0 0.414 -114.9 115.6 58.0 0.414 0.0 HOH
 9.089
 N
 O
6nqm 1 O60341 99.4 0.0 X-RAY
 2019-02-13 THR A:609 A:781 68.0 0.486 -126.5 125.9 68.0 0.486 0.0
6nqu 1 O60341 99.4 0.0 X-RAY
 2019-02-13 THR A:609 A:781 70.0 0.5 -122.7 128.5 70.0 0.5 0.0
6nr5 1 O60341 99.4 0.0 X-RAY
 2019-07-17 THR A:609 A:781 63.0 0.45 -142.4 117.4 63.0 0.45 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o60341-f1 1 O60341 94.98 0.0 THR A:781 A:781 53.0 0.379 -102.9 123.8