Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr1 | 23408840 | . | C | A | CCDS30627.1:NM_015013.3:c.2354tCg>tAg_NP_055828.2:p.785S>* | Homo sapiens lysine demethylase 1A (KDM1A), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 3zmu | 1 | O60341 | 99.54 | 0.0 |
X-RAY |
2013-06-12 | SER | A:805 | A:785 | 79.0 | 0.687 | S | -65.1 | -73.1 | 79.0 | 0.687 | 0.0 | ||||||
| 3zmv | 1 | O60341 | 99.54 | 0.0 |
X-RAY |
2013-06-12 | SER | A:805 | A:785 | 77.0 | 0.67 | S | -70.1 | -69.5 | 77.0 | 0.67 | 0.0 | ||||||
| 3zms | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | SER | A:805 | A:785 | 76.0 | 0.661 | S | -69.4 | -62.8 | 76.0 | 0.661 | 0.0 | ||||||
| 3zmt | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | SER | A:805 | A:785 | 83.0 | 0.722 | S | -70.6 | -69.2 | 83.0 | 0.722 | 0.0 | ||||||
| 3zmz | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | SER | A:805 | A:785 | 76.0 | 0.661 | S | -71.4 | -71.8 | 76.0 | 0.661 | 0.0 | ||||||
| 3zn0 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | SER | A:805 | A:785 | 78.0 | 0.678 | S | -67.7 | -68.4 | 78.0 | 0.678 | 0.0 | ||||||
| 3zn1 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2013-06-12 | SER | A:805 | A:785 | 75.0 | 0.652 | S | -69.3 | -73.6 | 75.0 | 0.652 | 0.0 | ||||||
| 4czz | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-06-11 | SER | A:805 | A:785 | 82.0 | 0.713 | S | -61.4 | -76.3 | 82.0 | 0.713 | 0.0 | ||||||
| 4uv8 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | SER | A:805 | A:785 | 75.0 | 0.652 | S | -66.6 | -66.6 | 75.0 | 0.652 | 0.0 | ||||||
| 4uv9 | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | SER | A:805 | A:785 | 77.0 | 0.67 | S | -67.0 | -73.0 | 77.0 | 0.67 | 0.0 | ||||||
| 4uva | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | SER | A:805 | A:785 | 77.0 | 0.67 | S | -66.1 | -70.5 | 77.0 | 0.67 | 0.0 | ||||||
| 4uvb | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | SER | A:805 | A:785 | 77.0 | 0.67 | S | -66.5 | -68.6 | 77.0 | 0.67 | 0.0 | ||||||
| 4uvc | 1 | O60341 | 99.43 | 0.0 |
X-RAY |
2014-09-10 | SER | A:805 | A:785 | 69.0 | 0.6 | S | -69.7 | -82.3 | 69.0 | 0.6 | 0.0 | ||||||
| 6tuy | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2021-07-21 | SER | A:785 | A:785 | 80.0 | 0.696 | S | -70.9 | -59.8 | 80.0 | 0.696 | 0.0 |
HOH |
2.588 |
N |
O |
||
| 2xaf | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | SER | A:785 | A:785 | 75.0 | 0.652 | S | -70.4 | -90.7 | 75.0 | 0.652 | 0.0 | ||||||
| 2xag | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | SER | A:785 | A:785 | 78.0 | 0.678 | S | -74.9 | -76.5 | 78.0 | 0.678 | 0.0 | ||||||
| 2xah | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | SER | A:785 | A:785 | 79.0 | 0.687 | S | -69.8 | -80.9 | 79.0 | 0.687 | 0.0 | ||||||
| 2xaj | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | SER | A:785 | A:785 | 72.0 | 0.626 | S | -72.7 | -88.9 | 72.0 | 0.626 | 0.0 | ||||||
| 2xaq | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | SER | A:785 | A:785 | 75.0 | 0.652 | S | -66.4 | -80.5 | 75.0 | 0.652 | 0.0 | ||||||
| 2xas | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2010-05-05 | SER | A:785 | A:785 | 70.0 | 0.609 | S | -66.2 | -90.8 | 70.0 | 0.609 | 0.0 | ||||||
| 4uxn | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2015-02-25 | SER | A:785 | A:785 | 84.0 | 0.73 | S | -72.2 | -53.6 | 84.0 | 0.73 | 0.0 | ||||||
| 5lhg | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | SER | A:785 | A:785 | 72.0 | 0.626 | S | -65.5 | -44.3 | 72.0 | 0.626 | 0.0 | ||||||
| 5lhh | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | SER | A:785 | A:785 | 72.0 | 0.626 | S | -64.6 | -68.9 | 72.0 | 0.626 | 0.0 | ||||||
| 5lhi | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2017-02-22 | SER | A:785 | A:785 | 72.0 | 0.626 | S | -61.5 | -57.6 | 72.0 | 0.626 | 0.0 | ||||||
| 6te1 | 1 | O60341 | 94.98 | 0.0 |
X-RAY |
2020-06-03 | SER | A:785 | A:785 | 66.0 | 0.574 | S | -65.0 | -70.0 | 66.0 | 0.574 | 0.0 | ||||||
| 5l3c | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | SER | A:785 | A:785 | 81.0 | 0.704 | S | -63.7 | -64.2 | 81.0 | 0.704 | 0.0 | ||||||
| 5l3d | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | SER | A:785 | A:785 | 81.0 | 0.704 | S | -66.0 | -58.2 | 81.0 | 0.704 | 0.0 | ||||||
| 5l3b | 1 | O60341 | 94.86 | 0.0 |
X-RAY |
2016-05-04 | SER | A:785 | A:785 | 78.0 | 0.678 | S | -64.5 | -60.9 | 78.0 | 0.678 | 0.0 | ||||||
| 2x0l | 1 | O60341 | 100.0 | 0.0 |
X-RAY |
2010-03-02 | SER | A:667 | A:785 | 75.0 | 0.652 | S | -61.9 | -74.3 | 75.0 | 0.652 | 0.0 | ||||||
| 4bay | 1 | O60341 | 99.85 | 0.0 |
X-RAY |
2013-11-27 | SER | A:619 | A:785 | 67.0 | 0.583 | S | -68.4 | -70.8 | 67.0 | 0.583 | 0.0 | ||||||
| 2v1d | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2007-05-29 | SER | A:663 | A:785 | 78.0 | 0.678 | S | -69.0 | -77.9 | 78.0 | 0.678 | 0.0 | ||||||
| 2y48 | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2011-02-16 | SER | A:663 | A:785 | 79.0 | 0.687 | S | -73.1 | -77.1 | 79.0 | 0.687 | 0.0 | ||||||
| 5l3e | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | SER | A:663 | A:785 | 82.0 | 0.713 | S | -73.2 | -66.4 | 82.0 | 0.713 | 0.0 | ||||||
| 5l3f | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | SER | A:663 | A:785 | 73.0 | 0.635 | S | -65.2 | -82.3 | 73.0 | 0.635 | 0.0 | ||||||
| 5l3g | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | SER | A:663 | A:785 | 79.0 | 0.687 | S | -79.1 | -67.3 | 79.0 | 0.687 | 0.0 | ||||||
| 5lbq | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2016-09-21 | SER | A:663 | A:785 | 74.0 | 0.643 | S | -59.9 | -59.4 | 74.0 | 0.643 | 0.0 | ||||||
| 5lgt | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2017-02-22 | SER | A:663 | A:785 | 75.0 | 0.652 | S | -77.8 | -60.5 | 75.0 | 0.652 | 0.0 | ||||||
| 5lgu | 1 | O60341 | 99.42 | 0.0 |
X-RAY |
2017-02-22 | SER | A:663 | A:785 | 75.0 | 0.652 | S | -74.0 | -54.5 | 75.0 | 0.652 | 0.0 | ||||||
| 6vyp | 7 | O60341 | 98.69 | 0.0 |
X-RAY |
2020-05-27 | SER | S:617 | M:785 | 81.0 | 0.704 | S | -75.9 | -32.9 | 81.0 | 0.704 | 0.0 | ||||||
| SER | U:617 | m:785 | 83.0 | 0.722 | S | -75.9 | -32.7 | NA | NA | NA | |||||||||||||
| SER | W:617 | K:785 | 83.0 | 0.722 | S | -75.6 | -33.2 | 83.0 | 0.722 | 0.0 | |||||||||||||
| SER | Y:617 | k:785 | 83.0 | 0.722 | S | -77.6 | -29.9 | NA | NA | NA | |||||||||||||
| 5lgn | 1 | O60341 | 99.85 | 0.0 |
X-RAY |
2017-02-22 | SER | A:619 | A:789 | 77.0 | 0.67 | S | -60.7 | -59.1 | 77.0 | 0.67 | 0.0 | ||||||
| 2iw5 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2006-08-09 | SER | A:615 | A:785 | 80.0 | 0.696 | S | -81.1 | -39.1 | 80.0 | 0.696 | 0.0 |
HOH |
2.656 |
OG |
O |
||
| 2uxn | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-05-29 | SER | A:615 | A:785 | 83.0 | 0.722 | S | -78.8 | -58.2 | 83.0 | 0.722 | 0.0 |
HOH |
2.645 |
OG |
O |
||
| 2uxx | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-08-21 | SER | A:615 | A:785 | 83.0 | 0.722 | S | -75.4 | -42.3 | 83.0 | 0.722 | 0.0 | ||||||
| 4kum | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2014-05-07 | SER | A:615 | A:785 | 75.0 | 0.652 | S | -82.3 | -40.4 | 75.0 | 0.652 | 0.0 |
HOH |
2.894 |
N |
O |
||
| 4xbf | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2016-04-27 | SER | A:615 | A:785 | 83.0 | 0.722 | S | -75.7 | -46.4 | 83.0 | 0.722 | 0.0 |
U U A G G G G |
6.957 3.353 5.162 3.781 8.421 6.840 8.542 |
HA OG HB3 HB3 O O O |
H5'' HO2' H5' OP2 OP2 O2' O5' |
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| 6wc6 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-30 | SER | A:615 | A:785 | 80.0 | 0.696 | S | -66.4 | -59.3 | 80.0 | 0.696 | 0.0 | ||||||
| 2h94 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2006-07-04 | SER | A:614 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2hko | 1 | O60341 | 99.25 | 0.0 |
X-RAY |
2006-08-29 | SER | A:614 | A:785 | 146.0 | 1.0 | -176.6 | 360.0 | 146.0 | 1.0 | 0.0 |
HOH |
5.987 |
N |
O |
|||
| 7e0g | 1 | O60341 | 99.1 | 0.0 |
X-RAY |
2021-03-24 | SER | A:617 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6s35 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-02-26 | SER | A:618 | A:785 | 80.0 | 0.696 | S | -81.3 | -58.6 | 80.0 | 0.696 | 0.0 | ||||||
| 5h6q | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | SER | A:621 | A:785 | 83.0 | 0.722 | S | -64.7 | -60.9 | 83.0 | 0.722 | 0.0 |
HOH |
8.535 |
OG |
O |
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| 5h6r | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | SER | A:621 | A:785 | 76.0 | 0.661 | S | -71.7 | -61.4 | 76.0 | 0.661 | 0.0 |
HOH |
8.108 |
OG |
O |
||
| 5x60 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2017-04-12 | SER | A:621 | A:785 | 82.0 | 0.713 | S | -68.7 | -54.5 | 82.0 | 0.713 | 0.0 | ||||||
| 5yjb | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2018-07-04 | SER | A:621 | A:785 | 72.0 | 0.626 | S | -58.5 | -70.4 | 72.0 | 0.626 | 0.0 | ||||||
| 6kgk | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | SER | A:621 | A:785 | 72.0 | 0.626 | S | -64.8 | -70.3 | 72.0 | 0.626 | 0.0 | ||||||
| 6kgl | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | SER | A:621 | A:785 | 69.0 | 0.6 | S | -65.7 | -69.7 | 69.0 | 0.6 | 0.0 | ||||||
| 6kgm | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | SER | A:621 | A:785 | 69.0 | 0.6 | S | -67.5 | -74.3 | 69.0 | 0.6 | 0.0 | ||||||
| 6kgn | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | SER | A:621 | A:785 | 69.0 | 0.6 | S | -67.8 | -74.2 | 69.0 | 0.6 | 0.0 | ||||||
| 6kgo | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | SER | A:621 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6kgp | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | SER | A:621 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6kgq | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | SER | A:621 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6kgr | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-03-25 | SER | A:621 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 7cdc | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | SER | A:621 | A:785 | 79.0 | 0.687 | S | -66.2 | -64.1 | 79.0 | 0.687 | 0.0 |
HOH |
2.552 |
OG |
O |
||
| 7cdd | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | SER | A:621 | A:785 | 77.0 | 0.67 | S | -68.4 | -67.6 | 77.0 | 0.67 | 0.0 |
HOH |
2.851 |
OG |
O |
||
| 7cde | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | SER | A:621 | A:785 | 79.0 | 0.687 | S | -63.3 | -63.1 | 79.0 | 0.687 | 0.0 |
HOH |
2.596 |
OG |
O |
||
| 7cdf | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | SER | A:621 | A:785 | 83.0 | 0.722 | S | -65.9 | -77.3 | 83.0 | 0.722 | 0.0 |
HOH |
2.696 |
OG |
O |
||
| 7cdg | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2021-06-23 | SER | A:621 | A:785 | 77.0 | 0.67 | S | -71.2 | -60.1 | 77.0 | 0.67 | 0.0 |
HOH |
2.475 |
OG |
O |
||
| 2ejr | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-01-01 | SER | A:614 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2z3y | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-01-01 | SER | A:614 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2z5u | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2008-04-01 | SER | A:614 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3abt | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2010-07-07 | SER | A:614 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3abu | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2010-07-07 | SER | A:614 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6k3e | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-05-20 | SER | A:614 | A:785 | 75.0 | 0.652 | S | -63.5 | -60.8 | 75.0 | 0.652 | 0.0 |
GOL GOL GOL EDO HOH |
6.652 7.270 3.504 8.738 9.468 |
OG OG OG OG N |
O2 O1 O1 O2 O |
||
| 2dw4 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2007-09-04 | SER | A:614 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6w4k | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2020-10-21 | SER | A:612 | A:785 | 75.0 | 0.652 | S | -74.1 | -67.7 | 75.0 | 0.652 | 0.0 |
HOH |
7.326 |
OG |
O |
||
| 6nqm | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-02-13 | SER | A:613 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6nqu | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-02-13 | SER | A:613 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6nr5 | 1 | O60341 | 99.4 | 0.0 |
X-RAY |
2019-07-17 | SER | A:613 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-o60341-f1 | 1 | O60341 | 94.98 | 0.0 | SER | A:785 | A:785 | 78.0 | 0.678 | S | -69.4 | -13.5 | |