Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 100661876 . G A CCDS767.1:NM_001918.3:c.1384Cgc>Tgc_NP_001909.3:p.462R>C Homo sapiens dihydrolipoamide branched chain transacylase E2 (DBT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ihw 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ARG A:242 A:401 158.0 0.702 H -50.8 -46.3 127.0 0.564 0.138 C:P11181:0.138
 ACT
HOH
 9.578
6.171
 NH2
N
 O
O
ARG B:242 B:401 157.0 0.698 H -73.7 -41.3 129.0 0.573 0.125 A:P11181:0.124
 ACT
HOH
 9.415
6.081
 NH2
N
 OXT
O
ARG C:242 C:401 160.0 0.711 H -62.8 -33.9 130.0 0.578 0.133 B:P11181:0.133
 ACT
HOH
 9.492
5.906
 NH2
N
 OXT
O
ARG D:242 D:401 162.0 0.72 H -56.3 -36.3 127.0 0.564 0.156 F:P11181:0.156
 ACT
HOH
 9.849
5.472
 NH2
NH2
 O
O
ARG E:242 E:401 167.0 0.742 H -57.7 -46.5 136.0 0.604 0.138 D:P11181:0.138
 ACT
HOH
 9.671
6.103
 NH2
N
 O
O
ARG F:242 F:401 158.0 0.702 H -61.2 -40.6 129.0 0.573 0.129 E:P11181:0.129
 ACT
HOH
 9.780
6.232
 NH2
N
 O
O
ARG G:242 G:401 168.0 0.747 H -59.1 -46.3 138.0 0.613 0.134 G:P11181:0.133
 HOH
 6.085
 N
 O
ARG H:242 H:401 161.0 0.716 H -70.5 -31.4 137.0 0.609 0.107 H:P11181:0.107
 ACT
HOH
 9.458
6.176
 NH1
N
 O
O
2ii3 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ARG A:242 A:401 153.0 0.68 H -59.7 -43.1 120.0 0.533 0.147 C:P11181:0.147
 ACT
CAO
HOH
 9.390
6.988
2.706
 NH1
NH2
NE
 OXT
N8P
O
ARG B:242 B:401 153.0 0.68 H -67.0 -42.6 126.0 0.56 0.12 A:P11181:0.12
 CAO
HOH
 6.938
2.388
 NH2
NH2
 O5P
O
ARG C:242 C:401 157.0 0.698 H -68.1 -37.4 127.0 0.564 0.134 B:P11181:0.133
 ACT
CAO
HOH
 9.554
7.091
2.616
 NH2
NH2
O
 CH3
N8P
O
ARG D:242 D:401 159.0 0.707 H -57.4 -43.4 134.0 0.596 0.111 F:P11181:0.111
 ACT
CAO
HOH
 9.759
6.761
2.665
 NH1
NH2
NE
 O
N8P
O
ARG E:242 E:401 162.0 0.72 H -62.1 -44.0 135.0 0.6 0.12 D:P11181:0.12
 ACT
CAO
ACT
HOH
 9.938
6.805
6.987
2.692
 NH1
NH2
NH1
O
 CH3
O9P
O
O
ARG F:242 F:401 156.0 0.693 H -56.7 -45.3 97.0 0.431 0.262 E:P11181:0.262
 CAO
HOH
 6.998
2.708
 NH2
O
 O5P
O
ARG G:242 G:401 154.0 0.684 H -61.5 -47.8 98.0 0.436 0.248 G:P11181:0.249
 CAO
HOH
 6.969
2.502
 NH2
NE
 O9P
O
ARG H:242 H:401 155.0 0.689 H -61.8 -39.8 130.0 0.578 0.111 H:P11181:0.111
 ACT
ACT
CAO
HOH
 6.800
9.633
6.684
2.428
 NH2
NH2
NH2
NE
 CH3
CH3
N8P
O
2ii4 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ARG A:242 A:401 141.0 0.627 H -62.8 -37.8 88.0 0.391 0.236 C:P11181:0.236
 COA
HOH
 6.848
2.483
 NH2
NE
 O5P
O
ARG B:242 B:401 145.0 0.644 H -67.6 -37.3 93.0 0.413 0.231 A:P11181:0.231
 COA
HOH
 7.194
2.456
 NH2
NE
 O9P
O
ARG C:242 C:401 141.0 0.627 H -74.1 -41.8 87.0 0.387 0.24 B:P11181:0.24
 COA
HOH
 6.909
2.299
 NH2
NE
 O5P
O
ARG D:242 D:401 145.0 0.644 H -65.8 -30.9 94.0 0.418 0.226 F:P11181:0.227
 COA
HOH
 6.998
2.510
 NH2
NE
 O5P
O
ARG E:242 E:401 167.0 0.742 H -67.3 -32.6 116.0 0.516 0.226 D:P11181:0.227
 COA
HOH
 6.790
4.141
 NH2
CA
 C7P
O
ARG F:242 F:401 140.0 0.622 H -55.5 -46.8 89.0 0.396 0.226 E:P11181:0.227
 COA
HOH
 7.051
2.441
 NH2
NE
 O5P
O
ARG G:242 G:401 143.0 0.636 H -63.5 -45.2 91.0 0.404 0.232 G:P11181:0.231
 COA
HOH
 7.098
2.522
 NH2
NE
 O5P
O
ARG H:242 H:401 138.0 0.613 H -70.4 -39.5 85.0 0.378 0.235 H:P11181:0.236
 COA
HOH
 6.857
2.154
 NH2
NE
 O5P
O
2ii5 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ARG A:242 A:401 156.0 0.693 H -60.1 -34.1 127.0 0.564 0.129 C:P11181:0.129
 ACT
CO6
HOH
 9.654
9.593
6.134
 NH2
NH1
N
 O
O2A
O
ARG B:242 B:401 154.0 0.684 H -75.3 -39.2 127.0 0.564 0.12 A:P11181:0.12
 ACT
CO6
HOH
 9.457
9.641
6.188
 NH2
NH1
N
 OXT
O2A
O
ARG C:242 C:401 157.0 0.698 H -70.8 -41.4 128.0 0.569 0.129 B:P11181:0.129
 ACT
HOH
 9.342
6.175
 NH2
N
 OXT
O
ARG D:242 D:401 159.0 0.707 H -63.5 -36.6 132.0 0.587 0.12 F:P11181:0.12
 ACT
HOH
 9.593
5.319
 NH2
NH2
 CH3
O
ARG E:242 E:401 164.0 0.729 H -58.4 -40.7 135.0 0.6 0.129 D:P11181:0.129
 CO6
HOH
 9.181
5.995
 NH2
N
 O1A
O
ARG F:242 F:401 154.0 0.684 H -55.5 -41.8 127.0 0.564 0.12 E:P11181:0.12
 ACT
CO6
HOH
 9.624
6.777
6.170
 NH2
NH2
N
 O
N8P
O
ARG G:242 G:401 163.0 0.724 H -59.8 -49.4 133.0 0.591 0.133 G:P11181:0.133
 ACT
CO6
HOH
 9.937
9.794
5.982
 NH2
NH1
N
 OXT
O2A
O
ARG H:242 H:401 153.0 0.68 H -68.0 -32.9 131.0 0.582 0.098 H:P11181:0.098
 ACT
CO6
HOH
 9.532
9.570
3.944
 NH1
NH2
NH1
 O
O2A
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11182-f1 1 P11182 100.0 0.0 ARG A:462 A:462 149.0 0.662 H -62.7 -43.5