Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 100661969 . G A CCDS767.1:NM_001918.3:c.1291Cga>Tga_NP_001909.3:p.431R>* Homo sapiens dihydrolipoamide branched chain transacylase E2 (DBT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ihw 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ARG A:211 A:370 82.0 0.364 E -138.8 149.2 24.0 0.107 0.257 C:P11181:0.236
B:P11181:0.022
 CL
HOH
 3.748
3.178
 NH2
CD
 CL
O
ARG B:211 B:370 77.0 0.342 E -142.1 152.8 29.0 0.129 0.213 C:P11181:0.013
A:P11181:0.2
 CL
HOH
 4.140
4.297
 NH2
NH2
 CL
O
ARG C:211 C:370 89.0 0.396 E -146.3 149.2 28.0 0.124 0.272 A:P11181:0.018
B:P11181:0.253
 CL
HOH
 3.580
4.252
 NH2
NH2
 CL
O
ARG D:211 D:370 76.0 0.338 E -144.2 153.9 32.0 0.142 0.196 F:P11181:0.182
E:P11181:0.013
 CL
HOH
 4.136
3.519
 NH2
CD
 CL
O
ARG E:211 E:370 87.0 0.387 E -151.9 155.5 34.0 0.151 0.236 F:P11181:0.013
D:P11181:0.222
 CL
HOH
 3.755
5.990
 NH2
NH2
 CL
O
ARG F:211 F:370 88.0 0.391 E -144.0 157.6 30.0 0.133 0.258 D:P11181:0.004
E:P11181:0.253
 CL
HOH
 3.668
5.404
 NH2
NH2
 CL
O
ARG G:211 G:370 80.0 0.356 -130.6 149.6 25.0 0.111 0.245 G:P11181:0.204
G:P11181:0.044
 CL
CL
CL
 3.553
3.553
3.553
 NH2
NH2
NH2
 CL
CL
CL
ARG H:211 H:370 87.0 0.387 E -140.0 155.6 30.0 0.133 0.254 H:P11181:0.018
H:P11181:0.236
 CL
CL
CL
HOH
 3.721
3.721
3.721
4.373
 NH2
NH2
NH2
NH2
 CL
CL
CL
O
2ii3 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ARG A:211 A:370 86.0 0.382 E -139.4 151.6 24.0 0.107 0.275 C:P11181:0.244
B:P11181:0.04
 CL
HOH
 3.681
3.070
 NH2
NH1
 CL
O
ARG B:211 B:370 88.0 0.391 E -136.0 152.6 31.0 0.138 0.253 C:P11181:0.036
A:P11181:0.227
 CL
HOH
 3.653
2.694
 NH2
NH1
 CL
O
ARG C:211 C:370 89.0 0.396 E -142.9 151.7 23.0 0.102 0.294 A:P11181:0.036
B:P11181:0.262
 CL
HOH
 3.430
3.225
 NH2
NH1
 CL
O
ARG D:211 D:370 86.0 0.382 E -142.8 148.5 28.0 0.124 0.258 F:P11181:0.222
E:P11181:0.036
 CL
HOH
 3.583
3.358
 NH2
NH1
 CL
O
ARG E:211 E:370 87.0 0.387 E -145.8 155.6 29.0 0.129 0.258 F:P11181:0.027
D:P11181:0.231
 CL
HOH
 3.690
2.621
 NH2
NH1
 CL
O
ARG F:211 F:370 85.0 0.378 E -141.3 154.0 30.0 0.133 0.245 D:P11181:0.036
E:P11181:0.209
 CL
HOH
 3.360
3.253
 NH2
NH1
 CL
O
ARG G:211 G:370 84.0 0.373 E -134.6 146.8 28.0 0.124 0.249 G:P11181:0.222
G:P11181:0.031
 CL
CL
CL
HOH
 3.572
3.549
3.564
3.396
 NH2
NH2
NH2
CD
 CL
CL
CL
O
ARG H:211 H:370 87.0 0.387 E -141.0 148.0 28.0 0.124 0.263 H:P11181:0.04
H:P11181:0.227
 CL
CL
CL
HOH
 3.419
3.405
3.430
3.602
 NH2
NH2
NH2
CD
 CL
CL
CL
O
2ii4 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ARG A:211 A:370 87.0 0.387 E -129.7 160.1 21.0 0.093 0.294 C:P11181:0.267
B:P11181:0.036
 CL
HOH
 3.460
3.151
 NH1
CD
 CL
O
ARG B:211 B:370 83.0 0.369 E -146.8 158.8 22.0 0.098 0.271 C:P11181:0.04
A:P11181:0.244
 CL
HOH
 3.160
3.347
 NH1
CD
 CL
O
ARG C:211 C:370 86.0 0.382 E -138.0 154.2 22.0 0.098 0.284 A:P11181:0.04
B:P11181:0.249
 CL
HOH
 3.298
3.270
 NH1
CD
 CL
O
ARG D:211 D:370 86.0 0.382 E -142.2 158.5 22.0 0.098 0.284 F:P11181:0.244
E:P11181:0.049
 CL
HOH
 3.326
3.439
 NH1
CD
 CL
O
ARG E:211 E:370 88.0 0.391 E -145.4 163.4 20.0 0.089 0.302 F:P11181:0.044
D:P11181:0.267
 CL
HOH
 3.195
3.908
 NH1
NH2
 CL
O
ARG F:211 F:370 90.0 0.4 E -133.1 161.7 24.0 0.107 0.293 D:P11181:0.053
E:P11181:0.249
 CL
HOH
 3.102
3.523
 NH2
CD
 CL
O
ARG G:211 G:370 87.0 0.387 E -132.7 147.5 25.0 0.111 0.276 G:P11181:0.231
G:P11181:0.062
 CL
CL
CL
HOH
 3.012
2.979
3.000
9.378
 NH1
NH1
NH1
NH2
 CL
CL
CL
O
ARG H:211 H:370 86.0 0.382 E -136.9 155.6 24.0 0.107 0.275 H:P11181:0.244
H:P11181:0.04
 CL
CL
CL
HOH
 3.380
3.345
3.397
3.361
 NH2
NH2
NH2
CD
 CL
CL
CL
O
2ii5 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ARG A:211 A:370 84.0 0.373 E -137.5 142.2 25.0 0.111 0.262 C:P11181:0.24
B:P11181:0.022
 CL
HOH
 3.609
3.601
 NH2
CA
 CL
O
ARG B:211 B:370 79.0 0.351 E -143.7 152.9 30.0 0.133 0.218 C:P11181:0.022
A:P11181:0.196
 CL
HOH
 4.035
3.792
 NH2
NH2
 CL
O
ARG C:211 C:370 85.0 0.378 E -144.8 144.4 26.0 0.116 0.262 A:P11181:0.027
B:P11181:0.236
 CL
HOH
 3.538
3.914
 NH2
NH2
 CL
O
ARG D:211 D:370 81.0 0.36 E -148.5 142.9 33.0 0.147 0.213 F:P11181:0.2
E:P11181:0.018
 CL
HOH
 3.763
3.673
 NH2
CD
 CL
O
ARG E:211 E:370 84.0 0.373 E -154.7 146.4 32.0 0.142 0.231 F:P11181:0.018
D:P11181:0.213
 CL
HOH
 3.767
6.059
 NH2
NH2
 CL
O
ARG F:211 F:370 86.0 0.382 E -145.4 148.1 28.0 0.124 0.258 D:P11181:0.018
E:P11181:0.244
 CL
HOH
 3.755
5.647
 NH2
NH2
 CL
O
ARG G:211 G:370 84.0 0.373 E -133.0 143.8 33.0 0.147 0.226 G:P11181:0.204
G:P11181:0.027
 CL
CL
CL
 3.586
3.585
3.585
 NH2
NH2
NH2
 CL
CL
CL
ARG H:211 H:370 86.0 0.382 E -141.2 149.4 29.0 0.129 0.253 H:P11181:0.031
H:P11181:0.222
 CL
CL
CL
HOH
 3.515
3.514
3.514
3.989
 NH2
NH2
NH2
NH2
 CL
CL
CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11182-f1 1 P11182 100.0 0.0 ARG A:431 A:431 80.0 0.356 E -132.0 156.4