Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 100671829 . A C CCDS767.1:NM_001918.3:c.1238aTa>aGa_NP_001909.3:p.413I>R Homo sapiens dihydrolipoamide branched chain transacylase E2 (DBT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ihw 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ILE A:193 A:352 0.0 0.0 -75.3 139.5 0.0 0.0 0.0 ACT
ACT
CL
CL
HOH
 4.558
9.559
6.746
9.354
4.039
 N
N
N
CD1
C
 O
O
CL
CL
O
ILE B:193 B:352 0.0 0.0 -57.5 138.2 0.0 0.0 0.0 CL
ACT
ACT
CL
HOH
 9.225
4.558
9.076
6.847
3.640
 CD1
N
N
N
CG2
 CL
O
CH3
CL
O
ILE C:193 C:352 0.0 0.0 -60.5 132.7 0.0 0.0 0.0 CL
ACT
ACT
CL
HOH
 9.377
4.762
9.288
6.757
5.967
 CD1
N
N
N
CG2
 CL
O
CH3
CL
O
ILE D:193 D:352 0.0 0.0 -58.4 142.1 0.0 0.0 0.0 ACT
ACT
CL
CL
HOH
 4.761
9.347
6.723
9.413
3.599
 N
N
N
CD1
CG2
 OXT
CH3
CL
CL
O
ILE E:193 E:352 0.0 0.0 -52.0 134.0 0.0 0.0 0.0 CL
ACT
ACT
CL
HOH
 9.509
4.859
9.797
6.754
4.016
 CD1
N
N
N
CA
 CL
O
CH3
CL
O
ILE F:193 F:352 0.0 0.0 -50.4 132.5 0.0 0.0 0.0 CL
ACT
ACT
CL
HOH
 9.991
4.671
9.648
6.792
3.904
 CD1
N
N
N
CA
 CL
OXT
OXT
CL
O
ILE G:193 G:352 0.0 0.0 -78.7 134.8 0.0 0.0 0.0 ACT
ACT
CL
CL
HOH
 4.836
9.389
7.045
9.540
3.532
 N
N
N
CD1
CA
 O
CH3
CL
CL
O
ILE H:193 H:352 0.0 0.0 -56.5 137.9 0.0 0.0 0.0 ACT
ACT
CL
CL
HOH
 4.715
9.502
9.215
6.892
3.686
 N
N
CD1
N
CA
 OXT
CH3
CL
CL
O
2ii3 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ILE A:193 A:352 0.0 0.0 -73.7 140.2 0.0 0.0 0.0 ACT
CL
CAO
CL
HOH
 4.647
6.769
9.397
9.281
3.793
 N
N
N
CD1
CG2
 O
CL
S1P
CL
O
ILE B:193 B:352 0.0 0.0 -70.3 141.7 0.0 0.0 0.0 CL
ACT
ACT
ACT
CL
HOH
 9.488
4.622
9.244
7.224
6.515
3.925
 CD1
N
N
C
N
CA
 CL
O
O
O
CL
O
ILE C:193 C:352 0.0 0.0 -64.3 138.7 0.0 0.0 0.0 CL
ACT
ACT
CL
HOH
 9.461
4.733
9.123
6.766
3.632
 CD1
N
N
N
CG2
 CL
O
O
CL
O
ILE D:193 D:352 0.0 0.0 -60.7 147.0 0.0 0.0 0.0 ACT
ACT
CL
CL
HOH
 4.741
9.506
6.589
9.655
3.925
 N
N
N
CD1
CA
 OXT
O
CL
CL
O
ILE E:193 E:352 0.0 0.0 -65.0 140.3 0.0 0.0 0.0 CL
ACT
CL
CAO
HOH
 9.611
4.814
6.670
9.320
3.902
 CD1
N
N
N
CA
 CL
O
CL
S1P
O
ILE F:193 F:352 0.0 0.0 -62.7 140.7 0.0 0.0 0.0 CL
ACT
ACT
CL
HOH
 9.477
4.707
9.501
6.598
3.832
 CD1
N
N
N
CA
 CL
OXT
OXT
CL
O
ILE G:193 G:352 0.0 0.0 -64.8 136.5 0.0 0.0 0.0 ACT
CL
CAO
CL
HOH
 5.048
6.778
9.384
9.608
3.949
 N
N
N
CD1
CA
 O
CL
S1P
CL
O
ILE H:193 H:352 0.0 0.0 -68.5 141.3 0.0 0.0 0.0 ACT
ACT
CL
CL
HOH
 4.742
9.296
6.507
9.464
3.650
 N
N
N
CD1
CG2
 OXT
O
CL
CL
O
2ii4 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ILE A:193 A:352 0.0 0.0 -69.9 137.2 0.0 0.0 0.0 CL
COA
CL
HOH
 6.792
9.056
9.853
3.929
 N
N
CD1
CG2
 CL
S1P
CL
O
ILE B:193 B:352 0.0 0.0 -66.4 141.2 0.0 0.0 0.0 CL
CL
COA
HOH
 9.903
6.622
9.117
3.697
 CD1
N
N
CG2
 CL
CL
S1P
O
ILE C:193 C:352 0.0 0.0 -60.5 130.9 0.0 0.0 0.0 CL
CL
COA
HOH
 9.803
6.667
9.163
3.534
 CD1
N
N
CG2
 CL
CL
S1P
O
ILE D:193 D:352 0.0 0.0 -62.1 140.5 0.0 0.0 0.0 CL
COA
CL
HOH
 6.706
9.224
9.658
3.638
 N
N
CD1
CG2
 CL
S1P
CL
O
ILE E:193 E:352 0.0 0.0 -69.3 148.3 0.0 0.0 0.0 CL
CL
COA
HOH
 9.866
6.699
9.147
3.718
 CD1
N
N
CG2
 CL
CL
S1P
O
ILE F:193 F:352 0.0 0.0 -55.4 138.0 0.0 0.0 0.0 CL
CL
COA
HOH
 9.830
6.754
9.256
4.087
 CD1
N
N
CA
 CL
CL
S1P
O
ILE G:193 G:352 0.0 0.0 -65.4 141.7 0.0 0.0 0.0 CL
COA
CL
HOH
 6.555
9.280
9.644
5.240
 N
N
CD1
N
 CL
S1P
CL
O
ILE H:193 H:352 0.0 0.0 -78.4 141.8 0.0 0.0 0.0 CL
COA
CL
HOH
 6.568
9.234
9.762
3.452
 N
N
CD1
CG2
 CL
S1P
CL
O
2ii5 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 ILE A:193 A:352 0.0 0.0 -68.0 145.8 0.0 0.0 0.0 ACT
ACT
CL
CL
HOH
 4.660
9.760
6.968
9.223
3.842
 N
N
N
CD1
CG2
 O
CH3
CL
CL
O
ILE B:193 B:352 0.0 0.0 -66.2 137.0 0.0 0.0 0.0 CL
ACT
ACT
CL
HOH
 9.388
4.629
9.182
6.566
3.759
 CD1
N
N
N
CG2
 CL
O
CH3
CL
O
ILE C:193 C:352 0.0 0.0 -64.9 136.9 0.0 0.0 0.0 CL
ACT
ACT
CL
HOH
 9.398
4.820
9.228
6.872
3.490
 CD1
N
N
N
CG2
 CL
O
CH3
CL
O
ILE D:193 D:352 0.0 0.0 -64.9 145.2 0.0 0.0 0.0 ACT
ACT
CL
CL
HOH
 4.804
9.591
6.714
9.511
3.767
 N
N
N
CD1
CG2
 OXT
OXT
CL
CL
O
ILE E:193 E:352 0.0 0.0 -66.1 142.5 0.0 0.0 0.0 CL
ACT
ACT
CL
HOH
 9.430
4.533
9.304
6.898
3.976
 CD1
N
N
N
CA
 CL
O
CH3
CL
O
ILE F:193 F:352 0.0 0.0 -55.8 142.7 0.0 0.0 0.0 CL
ACT
ACT
CL
HOH
 9.298
4.486
9.556
6.766
3.792
 CD1
N
N
N
CG2
 CL
OXT
OXT
CL
O
ILE G:193 G:352 0.0 0.0 -68.2 137.2 0.0 0.0 0.0 ACT
ACT
CL
CL
HOH
 4.791
9.429
7.113
9.311
3.794
 N
N
N
CD1
CA
 O
CH3
CL
CL
O
ILE H:193 H:352 0.0 0.0 -70.0 141.0 0.0 0.0 0.0 ACT
ACT
CL
CL
HOH
 4.744
9.266
6.955
9.368
3.561
 N
N
N
CD1
CA
 OXT
CH3
CL
CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11182-f1 1 P11182 100.0 0.0 ILE A:413 A:413 0.0 0.0 -62.0 144.4