Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 100680431 . A C CCDS767.1:NM_001918.3:c.881tTa>tGa_NP_001909.3:p.294L>* Homo sapiens dihydrolipoamide branched chain transacylase E2 (DBT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ihw 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 LEU A:74 A:233 66.0 0.388 H -91.2 -25.0 0.0 0.0 0.388 F:P11181:0.388
 HOH
 7.501
 N
 O
LEU B:74 B:233 70.0 0.412 H -82.6 -30.4 0.0 0.0 0.412 D:P11181:0.412
 HOH
 8.132
 CD1
 O
LEU C:74 C:233 66.0 0.388 H -82.5 -21.0 1.0 0.006 0.382 G:P11181:0.382
 HOH
 8.042
 N
 O
LEU D:74 D:233 65.0 0.382 H -87.8 -33.6 1.0 0.006 0.376 B:P11181:0.376
 HOH
 7.910
 N
 O
LEU E:74 E:233 69.0 0.406 H -89.5 -35.1 1.0 0.006 0.4 H:P11181:0.4
 HOH
 7.990
 CD1
 O
LEU F:74 F:233 59.0 0.347 H -79.7 -44.2 1.0 0.006 0.341 A:P11181:0.341
LEU G:74 G:233 71.0 0.418 H -79.1 -18.3 1.0 0.006 0.412 C:P11181:0.412
 HOH
 8.465
 CD1
 O
LEU H:74 H:233 68.0 0.4 H -79.9 -30.5 1.0 0.006 0.394 E:P11181:0.394
 HOH
 7.172
 CD2
 O
2ii3 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 LEU A:74 A:233 69.0 0.406 H -90.0 -16.7 1.0 0.006 0.4 F:P11181:0.4
 ACT
HOH
 7.936
5.784
 CD1
O
 CH3
O
LEU B:74 B:233 58.0 0.341 H -87.3 -24.2 0.0 0.0 0.341 D:P11181:0.341
 ACT
HOH
 7.739
4.828
 CD1
N
 CH3
O
LEU C:74 C:233 68.0 0.4 H -81.6 -30.2 0.0 0.0 0.4 G:P11181:0.4
 ACT
HOH
 7.766
6.650
 CD1
CD2
 CH3
O
LEU D:74 D:233 59.0 0.347 H -79.8 -36.5 0.0 0.0 0.347 B:P11181:0.347
 ACT
HOH
 7.766
6.999
 CD1
CD2
 CH3
O
LEU E:74 E:233 67.0 0.394 H -87.7 -35.5 0.0 0.0 0.394 H:P11181:0.394
 ACT
CAO
HOH
 7.688
9.965
5.532
 CD1
C
O
 CH3
O8A
O
LEU F:74 F:233 63.0 0.371 H -84.7 -27.6 0.0 0.0 0.371 A:P11181:0.371
 ACT
HOH
 7.793
7.091
 CD1
CD2
 CH3
O
LEU G:74 G:233 70.0 0.412 H -74.4 -40.5 0.0 0.0 0.412 C:P11181:0.412
 ACT
HOH
 7.913
7.904
 CD1
CD1
 CH3
O
LEU H:74 H:233 60.0 0.353 H -82.2 -29.3 0.0 0.0 0.353 E:P11181:0.353
 ACT
HOH
 7.602
6.769
 CD1
CD2
 CH3
O
2ii4 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 LEU A:74 A:233 64.0 0.376 H -95.7 -21.3 1.0 0.006 0.37 F:P11181:0.371
 HOH
 8.508
 CD1
 O
LEU B:74 B:233 70.0 0.412 H -95.1 -23.0 1.0 0.006 0.406 D:P11181:0.406
 HOH
 6.472
 CD2
 O
LEU C:74 C:233 61.0 0.359 H -82.0 -23.0 1.0 0.006 0.353 G:P11181:0.353
 HOH
 7.951
 CD1
 O
LEU D:74 D:233 57.0 0.335 H -87.0 -13.1 0.0 0.0 0.335 B:P11181:0.335
 HOH
 8.389
 CD1
 O
LEU E:74 E:233 68.0 0.4 H -93.2 -28.7 0.0 0.0 0.4 H:P11181:0.4
 HOH
 8.033
 CD1
 O
LEU F:74 F:233 66.0 0.388 H -78.5 -20.6 1.0 0.006 0.382 A:P11181:0.382
 HOH
 8.264
 CD1
 O
LEU G:74 G:233 67.0 0.394 H -83.8 -19.3 1.0 0.006 0.388 C:P11181:0.388
LEU H:74 H:233 64.0 0.376 H -87.0 -26.0 1.0 0.006 0.37 E:P11181:0.371
 HOH
 6.559
 CD2
 O
2ii5 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 LEU A:74 A:233 63.0 0.371 H -85.7 -30.7 1.0 0.006 0.365 F:P11181:0.365
LEU B:74 B:233 70.0 0.412 H -89.6 -10.8 0.0 0.0 0.412 D:P11181:0.412
 HOH
 9.897
 O
 O
LEU C:74 C:233 66.0 0.388 H -85.3 -17.0 0.0 0.0 0.388 G:P11181:0.388
 HOH
 7.746
 N
 O
LEU D:74 D:233 61.0 0.359 H -86.2 -10.5 1.0 0.006 0.353 B:P11181:0.353
 HOH
 7.941
 N
 O
LEU E:74 E:233 69.0 0.406 H -85.1 -25.1 0.0 0.0 0.406 H:P11181:0.406
 HOH
 7.912
 CD1
 O
LEU F:74 F:233 61.0 0.359 H -84.1 -29.4 1.0 0.006 0.353 A:P11181:0.353
LEU G:74 G:233 68.0 0.4 H -77.1 -37.7 0.0 0.0 0.4 C:P11181:0.4
 HOH
 8.106
 CD1
 O
LEU H:74 H:233 66.0 0.388 H -81.4 -20.5 0.0 0.0 0.388 E:P11181:0.388
 HOH
 7.298
 CD2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11182-f1 1 P11182 100.0 0.0 LEU A:294 A:294 63.0 0.371 H -79.1 -21.7