Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 100680492 . G A CCDS767.1:NM_001918.3:c.820Cct>Tct_NP_001909.3:p.274P>S Homo sapiens dihydrolipoamide branched chain transacylase E2 (DBT), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2ihw 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 PRO A:54 A:213 69.0 0.476 -64.7 103.5 5.0 0.034 0.442 C:P11181:0.441
 CL
CL
ACT
ACT
CL
HOH
 7.195
9.954
8.935
9.731
4.216
4.231
 C
CA
O
O
CA
C
 CL
CL
O
CH3
CL
O
PRO B:54 B:213 60.0 0.414 -75.4 102.7 3.0 0.021 0.393 A:P11181:0.393
 ACT
ACT
CL
CL
HOH
 8.929
9.311
4.412
7.184
3.920
 O
O
CA
C
C
 OXT
O
CL
CL
O
PRO C:54 C:213 64.0 0.441 -70.5 110.1 3.0 0.021 0.42 B:P11181:0.421
 ACT
ACT
CL
CL
HOH
 9.089
9.830
4.507
7.391
3.615
 O
O
CA
C
C
 OXT
CH3
CL
CL
O
PRO D:54 D:213 63.0 0.434 -60.1 100.9 5.0 0.034 0.4 F:P11181:0.4
 CL
ACT
ACT
CL
HOH
 7.267
8.762
9.525
4.438
3.956
 C
O
O
CA
CA
 CL
O
OXT
CL
O
PRO E:54 E:213 62.0 0.428 -72.9 111.1 5.0 0.034 0.394 D:P11181:0.393
 ACT
CL
CL
HOH
 9.299
4.355
7.064
3.919
 O
CA
C
CA
 O
CL
CL
O
PRO F:54 F:213 64.0 0.441 -66.0 105.3 6.0 0.041 0.4 E:P11181:0.4
 ACT
ACT
CL
CL
HOH
 8.822
9.426
4.543
7.181
4.400
 O
O
CA
C
CA
 OXT
OXT
CL
CL
O
PRO G:54 G:213 63.0 0.434 -67.2 108.1 5.0 0.034 0.4 G:P11181:0.4
 CL
CL
ACT
CL
HOH
 7.180
9.819
9.166
4.505
3.548
 C
CA
CB
CA
CA
 CL
CL
O
CL
O
PRO H:54 H:213 63.0 0.434 -67.5 110.6 4.0 0.028 0.406 H:P11181:0.407
 CL
ACT
CL
HOH
 4.277
9.401
7.350
3.688
 CA
O
C
CA
 CL
O
CL
O
2ii3 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 PRO A:54 A:213 68.0 0.469 -71.7 104.5 4.0 0.028 0.441 C:P11181:0.441
 CL
ACT
ACT
CL
HOH
 7.432
9.081
9.649
4.153
4.017
 C
O
O
CA
CA
 CL
OXT
O
CL
O
PRO B:54 B:213 63.0 0.434 -68.8 99.7 4.0 0.028 0.406 A:P11181:0.407
 ACT
CL
CAO
CL
HOH
 8.804
4.208
9.930
7.502
3.994
 O
CA
O
C
CA
 OXT
CL
S1P
CL
O
PRO C:54 C:213 63.0 0.434 -70.7 106.0 6.0 0.041 0.393 B:P11181:0.393
 ACT
ACT
CL
CL
HOH
 9.105
9.837
4.260
7.511
3.921
 O
O
CA
C
CA
 OXT
O
CL
CL
O
PRO D:54 D:213 63.0 0.434 -68.8 101.8 6.0 0.041 0.393 F:P11181:0.393
 CL
ACT
ACT
CL
HOH
 7.454
9.155
9.881
4.323
3.818
 C
O
O
CA
C
 CL
O
OXT
CL
O
PRO E:54 E:213 66.0 0.455 -73.2 108.7 4.0 0.028 0.427 D:P11181:0.428
 ACT
ACT
CL
CL
HOH
 9.080
9.857
4.139
7.444
3.943
 O
O
CA
C
CA
 O
O
CL
CL
O
PRO F:54 F:213 62.0 0.428 -72.1 103.8 4.0 0.028 0.4 E:P11181:0.4
 ACT
CL
CAO
CL
HOH
 8.933
4.234
9.947
7.361
4.183
 O
CA
O
N
C
 OXT
CL
S1P
CL
O
PRO G:54 G:213 66.0 0.455 -74.9 104.1 5.0 0.034 0.421 G:P11181:0.421
 CL
ACT
CL
CAO
HOH
 7.405
9.078
4.242
9.871
3.742
 C
O
CA
O
CA
 CL
OXT
CL
S1P
O
PRO H:54 H:213 67.0 0.462 -72.7 105.1 4.0 0.028 0.434 H:P11181:0.434
 CL
ACT
ACT
CL
HOH
 7.481
9.059
9.802
4.119
3.929
 N
O
O
CA
CA
 CL
O
O
CL
O
2ii4 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 PRO A:54 A:213 63.0 0.434 -73.5 110.1 6.0 0.041 0.393 C:P11181:0.393
 CL
CL
HOH
 7.066
4.463
3.700
 C
CA
CA
 CL
CL
O
PRO B:54 B:213 63.0 0.434 -75.4 102.7 6.0 0.041 0.393 A:P11181:0.393
 CL
COA
CL
HOH
 4.338
9.857
7.233
3.889
 CA
O
C
CA
 CL
S1P
CL
O
PRO C:54 C:213 64.0 0.441 -78.9 115.4 6.0 0.041 0.4 B:P11181:0.4
 CL
CL
HOH
 4.241
6.895
3.505
 CA
C
CA
 CL
CL
O
PRO D:54 D:213 63.0 0.434 -73.1 112.9 5.0 0.034 0.4 F:P11181:0.4
 CL
CL
HOH
 7.178
4.313
3.766
 C
CA
CA
 CL
CL
O
PRO E:54 E:213 63.0 0.434 -70.7 108.5 6.0 0.041 0.393 D:P11181:0.393
 CL
CL
HOH
 4.284
7.059
3.834
 CA
C
CA
 CL
CL
O
PRO F:54 F:213 61.0 0.421 -77.7 111.0 5.0 0.034 0.387 E:P11181:0.386
 CL
CL
HOH
 4.433
7.163
3.934
 CA
C
CA
 CL
CL
O
PRO G:54 G:213 63.0 0.434 -73.1 104.7 6.0 0.041 0.393 G:P11181:0.393
 CL
CL
HOH
 7.042
4.523
3.876
 C
CA
C
 CL
CL
O
PRO H:54 H:213 65.0 0.448 -70.6 109.2 7.0 0.048 0.4 H:P11181:0.4
 CL
CL
HOH
 7.264
4.228
3.465
 C
CA
CA
 CL
CL
O
2ii5 1 P11181 91.51 3e-176 X-RAY
 2006-12-26 PRO A:54 A:213 66.0 0.455 -71.2 97.9 4.0 0.028 0.427 C:P11181:0.428
 CL
ACT
ACT
CL
HOH
 7.402
8.768
9.645
4.190
4.182
 C
O
O
CA
CA
 CL
OXT
CH3
CL
O
PRO B:54 B:213 63.0 0.434 -72.1 105.5 3.0 0.021 0.413 A:P11181:0.414
 ACT
ACT
CL
CL
HOH
 8.881
9.504
4.227
7.311
3.822
 O
O
CA
C
CA
 OXT
O
CL
CL
O
PRO C:54 C:213 64.0 0.441 -75.3 109.9 3.0 0.021 0.42 B:P11181:0.421
 CL
ACT
ACT
CL
CL
HOH
 9.963
8.972
9.883
4.417
7.463
3.563
 CA
CB
O
CA
C
CA
 CL
O
CH3
CL
CL
O
PRO D:54 D:213 63.0 0.434 -64.8 98.7 6.0 0.041 0.393 F:P11181:0.393
 CL
ACT
ACT
CL
HOH
 7.315
8.828
9.741
4.497
3.967
 C
O
O
CA
CA
 CL
O
OXT
CL
O
PRO E:54 E:213 62.0 0.428 -80.9 107.1 5.0 0.034 0.394 D:P11181:0.393
 ACT
ACT
CL
CL
HOH
 9.180
9.922
4.340
7.173
3.839
 O
O
CA
C
CA
 O
OXT
CL
CL
O
PRO F:54 F:213 61.0 0.421 -77.7 101.6 5.0 0.034 0.387 E:P11181:0.386
 ACT
ACT
CL
CL
HOH
 8.648
9.527
4.422
7.204
4.174
 O
O
CA
C
CA
 OXT
OXT
CL
CL
O
PRO G:54 G:213 65.0 0.448 -72.2 105.0 4.0 0.028 0.42 G:P11181:0.421
 CL
CL
ACT
ACT
CL
HOH
 7.285
9.825
9.190
9.946
4.280
3.679
 C
CA
CB
O
CA
CA
 CL
CL
O
O
CL
O
PRO H:54 H:213 66.0 0.455 -73.2 108.7 4.0 0.028 0.427 H:P11181:0.428
 CL
ACT
ACT
CL
CL
HOH
 7.370
9.257
10.000
4.235
9.991
3.826
 C
CB
O
CA
CA
CA
 CL
OXT
CH3
CL
CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11182-f1 1 P11182 100.0 0.0 PRO A:274 A:274 63.0 0.434 -73.5 105.4