Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104115703 . G A CCDS782.1:NM_020978.4:c.334Gct>Act_NP_066188.1:p.112A>T Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ALA A:97 A:97 0.0 0.0 E -89.9 113.2 0.0 0.0 0.0 G6D
CL
ACI
HOH
 9.555
9.876
7.462
3.454
 O
N
O
CA
 O3
CL
O6
O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ALA A:97 A:97 0.0 0.0 E -90.9 110.8 0.0 0.0 0.0 G6D
CL
ACI
HOH
 9.569
9.891
7.399
3.336
 O
N
O
CA
 O3
CL
O6
O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ALA A:97 A:97 0.0 0.0 E -89.1 112.6 0.0 0.0 0.0 G6D
CL
HSD
HOH
 9.661
9.907
7.700
3.303
 O
N
O
CA
 O3
CL
O1
O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ALA A:97 A:97 0.0 0.0 E -89.8 112.6 0.0 0.0 0.0 G6D
CL
HSD
HOH
 9.619
9.925
7.379
3.358
 O
N
O
CA
 O3
CL
O1
O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 ALA A:97 A:97 0.0 0.0 E -95.4 112.1 0.0 0.0 0.0 GLC
CL
HOH
 9.287
9.213
2.503
 O
H
HA
 HO1
CL
O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 ALA A:97 A:97 0.0 0.0 E -93.1 110.5 0.0 0.0 0.0 AC1
CL
HOH
 7.598
9.874
3.511
 O
N
CA
 O6B
CL
O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 ALA A:97 A:97 0.0 0.0 E -96.6 112.7 0.0 0.0 0.0 CL
HOH
 9.951
3.303
 N
CA
 CL
O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 ALA A:97 A:97 0.0 0.0 E -94.8 111.4 0.0 0.0 0.0 AGL
CL
HMC
HOH
 9.550
9.923
7.637
3.312
 O
N
O
CA
 O3
CL
O7
O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 ALA A:97 A:97 0.0 0.0 E -95.0 112.2 0.0 0.0 0.0 CL
HOH
 9.998
3.356
 N
CA
 CL
O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ALA A:97 A:97 0.0 0.0 E -93.3 111.2 0.0 0.0 0.0 CL
GOX
HOH
 9.962
8.600
3.409
 N
O
CA
 CL
O2
O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ALA A:97 A:97 0.0 0.0 E -90.4 108.4 0.0 0.0 0.0 LAG
CL
HOH
 7.688
9.912
3.299
 O
N
CA
 OA6
CL
O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ALA A:97 A:97 0.0 0.0 E -88.0 111.2 0.0 0.0 0.0 LM2
CL
HOH
 7.616
9.788
3.377
 O
N
CA
 OA6
CL
O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ALA A:97 A:97 0.0 0.0 E -91.4 114.7 0.0 0.0 0.0 AC1
HOH
 7.478
3.423
 O
CA
 O6B
O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ALA A:97 A:97 0.0 0.0 E -92.6 112.0 0.0 0.0 0.0 AC1
CL
HOH
 7.401
9.929
3.363
 O
N
CA
 O6B
CL
O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ALA A:97 A:97 0.0 0.0 E -92.7 112.6 0.0 0.0 0.0 ARE
CL
HOH
 7.671
9.909
3.356
 O
N
CA
 O7H
CL
O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ALA A:97 A:97 0.0 0.0 E -95.7 113.7 0.0 0.0 0.0 6SA
CL
HOH
 7.961
9.890
3.302
 O
N
CA
 OQ7
CL
O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ALA A:97 A:97 0.0 0.0 E -91.1 106.8 0.0 0.0 0.0 NO2
HOH
 9.578
3.393
 N
CA
 O1
O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ALA A:97 A:97 0.0 0.0 E -92.4 110.5 0.0 0.0 0.0 NO2
QV4
HOH
 9.173
8.348
3.385
 N
O
CA
 O2
C6T
O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ALA A:97 A:97 0.0 0.0 E -94.7 109.4 0.0 0.0 0.0 NO3
HOH
 9.406
3.398
 N
CA
 O2
O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ALA A:97 A:97 0.0 0.0 E -93.2 107.6 0.0 0.0 0.0 ARE
NO3
HOH
 8.108
9.376
3.421
 O
N
CA
 C6H
O2
O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ALA A:97 A:97 0.0 0.0 E -93.0 109.6 0.0 0.0 0.0 CL
AZI
NA
HOH
 9.863
9.836
9.292
3.466
 N
O
O
CA
 CL
N1
NA
O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ALA A:97 A:97 0.0 0.0 E -86.3 114.4 0.0 0.0 0.0 B9D
CL
HOH
 6.900
9.929
3.501
 O
N
CA
 C5
CL
O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ALA A:97 A:97 0.0 0.0 E -90.2 113.4 0.0 0.0 0.0 B0D
B9D
CL
HOH
 9.704
6.905
9.880
3.350
 O
O
N
CA
 O3
C5
CL
O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ALA A:97 A:97 0.0 0.0 E -88.4 113.4 0.0 0.0 0.0 B9D
CL
HOH
 6.773
9.905
3.379
 O
N
CA
 C5
CL
O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 ALA A:97 A:97 0.0 0.0 E -92.4 108.6 0.0 0.0 0.0 CL
HOH
 9.504
3.424
 N
CA
 CL
O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 ALA A:97 A:97 0.0 0.0 E -89.3 108.4 0.0 0.0 0.0 CL
MYC
HOH
 9.892
7.121
3.382
 N
O
CA
 CL
O25
O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 ALA A:97 A:97 0.0 0.0 E -94.7 111.1 0.0 0.0 0.0 CL
3L9
HOH
 9.993
7.192
3.340
 N
O
CA
 CL
O29
O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 ALA A:97 A:97 0.0 0.0 E -93.1 110.6 0.0 0.0 0.0 CL
HOH
 9.405
2.481
 H
HA
 CL
O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 ALA A:97 A:97 0.0 0.0 E -99.2 111.3 0.0 0.0 0.0 5J7
CL
HOH
 6.699
9.382
2.483
 O
H
HA
 H19
CL
O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 ALA A:97 A:97 0.0 0.0 E -93.8 111.9 0.0 0.0 0.0 5QP
CL
HOH
 6.529
9.372
2.482
 O
H
HA
 HAG1
CL
O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 ALA A:97 A:97 0.0 0.0 E -94.8 115.4 0.0 0.0 0.0 CL
HOH
 9.990
3.453
 N
CA
 CL
O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 ALA A:97 A:97 0.0 0.0 E -93.7 111.1 0.0 0.0 0.0 CL
HOH
 9.369
2.463
 H
HA
 CL
O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 ALA A:97 A:97 0.0 0.0 E -91.5 108.8 0.0 0.0 0.0 HOH
 3.291
 CA
 O
ALA B:97 B:97 0.0 0.0 E -92.1 110.0 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 ALA A:97 A:97 0.0 0.0 E -94.6 112.8 0.0 0.0 0.0 CL
ZXU
HOH
 9.422
6.929
2.472
 H
O
HA
 CL
HO40
O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 ALA A:97 A:97 0.0 0.0 E -94.5 111.3 0.0 0.0 0.0 ZXY
CL
HOH
 6.828
9.425
2.459
 O
H
HA
 HO18
CL
O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ALA A:97 A:97 0.0 0.0 E -96.2 111.5 0.0 0.0 0.0 HOH
 3.383
 CA
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ALA A:97 A:97 0.0 0.0 E -92.8 109.9 0.0 0.0 0.0 AAO
HOH
 8.550
3.333
 O
CA
 C6H
O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ALA A:97 A:97 0.0 0.0 E -94.8 108.5 0.0 0.0 0.0 CL
HOH
 9.973
3.367
 N
CA
 CL
O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ALA A:97 A:97 0.0 0.0 E -94.8 109.9 0.0 0.0 0.0 ARE
CL
HOH
 8.056
9.947
3.295
 O
N
CA
 C6H
CL
O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ALA A:97 A:97 0.0 0.0 E -96.3 111.1 0.0 0.0 0.0 NO3
HOH
 9.256
3.391
 N
CA
 O2
O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ALA A:97 A:97 0.0 0.0 E -90.8 108.2 0.0 0.0 0.0 AZI
NA
HOH
 9.973
8.861
3.415
 O
O
CA
 N1
NA
O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ALA A:97 A:97 0.0 0.0 E -96.9 113.4 0.0 0.0 0.0 ARE
NO3
HOH
 7.963
9.394
3.454
 O
O
CA
 C6H
O1
O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ALA A:97 A:97 0.0 0.0 E -92.0 116.4 0.0 0.0 0.0 HOH
 3.280
 CA
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 ALA A:97 A:97 0.0 0.0 E -96.8 113.4 0.0 0.0 0.0 CL
HOH
 9.897
3.286
 N
CA
 CL
O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 ALA A:97 A:97 0.0 0.0 E -96.3 114.7 0.0 0.0 0.0 CL
HOH
 9.875
3.271
 N
CA
 CL
O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 ALA A:97 A:97 0.0 0.0 E -90.2 107.5 0.0 0.0 0.0 GLC
GLC
CL
HOH
 9.786
7.562
9.899
3.375
 O
O
N
CA
 O3
O6
CL
O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ALA A:97 A:97 0.0 0.0 E -90.1 111.6 0.0 0.0 0.0 HOH
 3.346
 CA
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 ALA A:97 A:97 0.0 0.0 E -92.8 111.0 0.0 0.0 0.0 CL
HOH
 9.955
3.401
 N
CA
 CL
O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ALA A:97 A:97 0.0 0.0 E -92.0 114.2 0.0 0.0 0.0 HOH
 3.331
 CA
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 ALA A:97 A:97 0.0 0.0 E -94.9 114.9 0.0 0.0 0.0 HOH
 3.262
 CA
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 ALA A:97 A:97 0.0 0.0 E -94.0 116.9 0.0 0.0 0.0 CL
HOH
 9.966
2.753
 N
O
 CL
O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 ALA A:97 A:97 0.0 0.0 E -86.6 108.1 0.0 0.0 0.0 CL
HOH
 9.840
3.214
 N
CA
 CL
O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 ALA A:97 A:97 0.0 0.0 E -93.3 114.3 0.0 0.0 0.0 AGL
HMC
CL
HOH
 9.492
7.399
9.782
3.351
 O
O
N
CA
 O3
O7
CL
O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 ALA A:97 A:97 0.0 0.0 E -93.5 109.1 0.0 0.0 0.0 CL
HOH
 9.934
3.310
 N
CA
 CL
O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 ALA A:97 A:97 0.0 0.0 E -78.4 113.9 0.0 0.0 0.0 HOH
 3.093
 CA
 O
ALA B:97 B:97 0.0 0.0 E -78.4 113.9 0.0 0.0 0.0 HOH
 3.092
 CA
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 ALA A:97 X:97 0.0 0.0 E -87.5 109.2 0.0 0.0 0.0 CL
TAM
HOH
 9.848
7.275
3.412
 N
O
CA
 CL
O6
O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 ALA A:97 X:97 0.0 0.0 E -93.9 109.4 0.0 0.0 0.0 AGL
HMC
CL
HOH
 9.664
7.336
9.772
3.406
 O
O
N
CA
 O3
O7
CL
O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 ALA A:97 A:97 0.0 0.0 E -92.1 111.6 0.0 0.0 0.0 CL
HOH
 9.797
3.267
 N
CA
 CL
O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 ALA A:97 A:97 0.0 0.0 E -97.0 109.0 0.0 0.0 0.0 AGL
HMC
CL
HOH
 9.588
7.393
9.690
3.354
 O
O
N
CA
 O3
O7
CL
O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 ALA A:97 A:97 0.0 0.0 E -96.6 119.1 0.0 0.0 0.0 AGL
CL
HMC
HOH
 9.783
9.889
7.811
3.432
 O
N
O
CA
 O3
CL
O7
O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 ALA A:97 X:97 0.0 0.0 E -93.5 114.2 0.0 0.0 0.0 AGL
CL
HMC
HOH
 9.603
9.863
7.453
3.374
 O
N
O
CA
 O3
CL
O7
O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 ALA A:97 A:97 0.0 0.0 E -93.6 109.9 0.0 0.0 0.0 CL
HOH
 9.767
3.354
 N
CA
 CL
O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 ALA A:97 A:97 0.0 0.0 E -89.8 109.2 0.0 0.0 0.0 AGL
HMC
CL
HOH
 9.442
7.476
9.761
3.467
 O
O
N
CA
 O3
O7
CL
O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 ALA A:97 A:97 0.0 0.0 E -96.2 111.0 0.0 0.0 0.0 AGL
CL
HMC
HOH
 9.613
9.898
7.287
3.352
 O
N
O
CA
 O3
CL
O7
O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ALA A:97 A:97 0.0 0.0 E -93.0 108.6 0.0 0.0 0.0 CL
HOH
 9.880
3.380
 N
CA
 CL
O
ALA B:97 B:97 1.0 0.009 E -91.7 111.2 NA NA NA
ALA C:97 C:97 1.0 0.009 E -91.0 108.3 NA NA NA
ALA D:97 D:97 0.0 0.0 E -92.5 108.7 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ALA A:97 A:97 0.0 0.0 E -94.6 108.2 0.0 0.0 0.0 CL
HOH
 9.768
3.537
 N
CA
 CL
O
ALA C:97 C:97 0.0 0.0 E -85.8 113.8 NA NA NA
ALA E:97 E:97 0.0 0.0 E -89.3 103.0 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ALA A:97 A:97 0.0 0.0 E -94.6 111.3 0.0 0.0 0.0 HOH
 3.364
 CA
 O
ALA B:97 B:97 0.0 0.0 E -89.2 112.6 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 ALA A:97 A:97 0.0 0.0 E -89.2 109.4 0.0 0.0 0.0 CL
HOH
 9.633
2.851
 H
CA
 CL
H2
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 ALA A:97 A:97 0.0 0.0 E -90.7 111.8 0.0 0.0 0.0 DAF
CL
HOH
 7.375
9.941
3.338
 O
N
CA
 O7H
CL
O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 ALA A:97 A:97 0.0 0.0 E -93.8 106.8 0.0 0.0 0.0 GLC
CL
HOH
 7.219
9.444
2.571
 O
H
HA
 HO6
CL
O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 ALA A:97 A:97 0.0 0.0 E -92.1 107.9 0.0 0.0 0.0 CL
HOH
 9.474
2.561
 H
HA
 CL
O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 ALA A:97 A:97 0.0 0.0 E -96.3 110.0 0.0 0.0 0.0 GLC
CL
HOH
 7.402
9.800
3.424
 O
N
CA
 O6
CL
O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 ALA A:97 A:97 0.0 0.0 E -86.7 106.9 0.0 0.0 0.0 HOH
 3.553
 CA
 O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 ALA A:97 A:97 0.0 0.0 E -92.4 107.6 0.0 0.0 0.0 CL
HOH
 9.917
3.490
 N
CA
 CL
O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 ALA A:97 A:97 0.0 0.0 E -90.1 107.8 0.0 0.0 0.0 AC1
CL
HOH
 7.740
9.949
3.382
 O
N
CA
 O6B
CL
O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 ALA A:97 A:97 0.0 0.0 E -91.5 110.0 0.0 0.0 0.0 AC1
CL
HOH
 7.416
9.818
3.368
 O
N
CA
 O6B
CL
O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 ALA A:97 A:97 0.0 0.0 E -86.2 107.6 0.0 0.0 0.0 BGC
HOH
 7.637
3.408
 O
CA
 O6
O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 ALA A:97 P:97 0.0 0.0 E -96.4 99.4 0.0 0.0 0.0 HOH
 4.504
 O
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 ALA A:97 A:97 0.0 0.0 E -90.3 107.7 0.0 0.0 0.0 CL
HOH
 9.974
3.297
 N
CA
 CL
O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 ALA A:97 A:97 0.0 0.0 E -93.3 109.5 0.0 0.0 0.0 AGL
HMC
CL
HOH
 9.541
8.107
9.880
4.113
 O
O
N
O
 O3
O7
CL
O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 ALA A:97 A:97 0.0 0.0 E -92.1 110.3 0.0 0.0 0.0 CL
HOH
 9.957
3.505
 N
CA
 CL
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 ALA A:112 A:112 0.0 0.0 E -99.7 103.5
af-p04746-f1 1 P04746 98.83 0.0 ALA A:112 A:112 0.0 0.0 E -101.7 103.9
af-p0dte7-f1 1 P0DTE7 97.46 0.0 ALA A:112 A:112 0.0 0.0 E -98.1 101.3
af-p0dte8-f1 1 P0DTE8 97.46 0.0 ALA A:112 A:112 0.0 0.0 E -98.7 101.5
af-p0dub6-f1 1 P0DUB6 97.46 0.0 ALA A:112 A:112 0.0 0.0 E -97.9 100.5