Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104115739 . G A CCDS782.1:NM_020978.4:c.370Gca>Aca_NP_066188.1:p.124A>T Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ALA A:109 A:109 47.0 0.409 S -67.7 148.9 47.0 0.409 0.0 HOH
 3.259
 C
 O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ALA A:109 A:109 49.0 0.426 S -65.9 148.0 49.0 0.426 0.0 HOH
 2.857
 N
 O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ALA A:109 A:109 48.0 0.417 S -76.5 157.2 48.0 0.417 0.0 HOH
 3.080
 N
 O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 ALA A:109 A:109 47.0 0.409 S -69.4 150.1 47.0 0.409 0.0 HOH
 2.907
 N
 O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 ALA A:109 A:109 48.0 0.417 S -69.1 152.6 48.0 0.417 0.0 HOH
 2.174
 H
 O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 ALA A:109 A:109 46.0 0.4 S -71.7 156.2 46.0 0.4 0.0 HOH
 3.214
 C
 O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 ALA A:109 A:109 46.0 0.4 S -69.4 153.3 46.0 0.4 0.0 HOH
 3.182
 N
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 ALA A:109 A:109 48.0 0.417 S -69.9 149.3 48.0 0.417 0.0 HOH
 3.205
 N
 O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 ALA A:109 A:109 44.0 0.383 S -69.6 158.5 44.0 0.383 0.0 HOH
 3.524
 C
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ALA A:109 A:109 50.0 0.435 S -69.0 150.8 50.0 0.435 0.0 HOH
 3.259
 N
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ALA A:109 A:109 55.0 0.478 S -74.9 147.1 55.0 0.478 0.0 HOH
 3.522
 C
 O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 ALA A:109 A:109 49.0 0.426 S -67.7 159.7 49.0 0.426 0.0 HOH
 2.744
 N
 O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ALA A:109 A:109 48.0 0.417 -71.5 150.6 48.0 0.417 0.0 HOH
 2.985
 N
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ALA A:109 A:109 49.0 0.426 S -69.1 154.7 49.0 0.426 0.0 HOH
 3.033
 N
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ALA A:109 A:109 48.0 0.417 S -69.3 152.5 48.0 0.417 0.0 HOH
 3.154
 N
 O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 ALA A:109 A:109 45.0 0.391 S -66.7 162.5 45.0 0.391 0.0 HOH
 2.948
 N
 O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ALA A:109 A:109 50.0 0.435 -75.7 155.5 50.0 0.435 0.0 HOH
 4.698
 O
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ALA A:109 A:109 48.0 0.417 -69.7 154.6 48.0 0.417 0.0 QV4
HOH
 8.592
3.013
 N
N
 O4Q
O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ALA A:109 A:109 48.0 0.417 -67.5 156.5 48.0 0.417 0.0 HOH
 3.030
 N
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ALA A:109 A:109 48.0 0.417 -75.4 162.1 48.0 0.417 0.0 HOH
 3.117
 N
 O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 ALA A:109 A:109 46.0 0.4 S -68.5 159.2 46.0 0.4 0.0 HOH
 2.933
 N
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ALA A:109 A:109 46.0 0.4 -69.6 151.0 46.0 0.4 0.0 HOH
 2.958
 N
 O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ALA A:109 A:109 50.0 0.435 -74.3 150.0 50.0 0.435 0.0 HOH
 2.870
 N
 O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 ALA A:109 A:109 48.0 0.417 -71.6 150.2 48.0 0.417 0.0 HOH
 2.873
 N
 O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 ALA A:109 A:109 109.0 0.948 T -58.8 -13.0 109.0 0.948 0.0 HOH
 4.716
 N
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 ALA A:109 A:109 48.0 0.417 S -69.2 154.6 48.0 0.417 0.0 HOH
 2.909
 O
 O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 ALA A:109 A:109 50.0 0.435 -68.8 152.4 50.0 0.435 0.0 HOH
 2.833
 N
 O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 ALA A:109 A:109 49.0 0.426 S -67.6 152.5 49.0 0.426 0.0 HOH
 2.106
 H
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 ALA A:109 A:109 48.0 0.417 S -68.3 150.7 48.0 0.417 0.0 HOH
 2.129
 H
 O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 ALA A:109 A:109 49.0 0.426 S -70.2 152.8 49.0 0.426 0.0 HOH
 2.051
 H
 O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 ALA A:109 A:109 46.0 0.4 -64.8 160.8 46.0 0.4 0.0 HOH
 2.872
 N
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 ALA A:109 A:109 48.0 0.417 S -67.6 152.0 48.0 0.417 0.0 HOH
 2.081
 H
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 ALA A:109 A:109 48.0 0.417 -65.9 147.5 48.0 0.417 0.0 HOH
 2.751
 N
 O
ALA B:109 B:109 47.0 0.409 -65.8 148.2 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 ALA A:109 A:109 48.0 0.417 S -69.1 152.2 48.0 0.417 0.0 MPD
HOH
 9.454
2.063
 N
H
 HO2
O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 ALA A:109 A:109 49.0 0.426 S -68.6 153.7 49.0 0.426 0.0 HOH
 2.084
 H
 O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ALA A:109 A:109 50.0 0.435 S -68.5 151.4 50.0 0.435 0.0 HOH
 2.823
 N
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ALA A:109 A:109 49.0 0.426 -68.0 157.5 49.0 0.426 0.0 HOH
 3.086
 N
 O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ALA A:109 A:109 49.0 0.426 -72.3 160.4 49.0 0.426 0.0 HOH
 2.961
 N
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 ALA A:109 A:109 46.0 0.4 -64.2 160.9 46.0 0.4 0.0 HOH
 3.054
 N
 O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ALA A:109 A:109 48.0 0.417 S -66.8 153.6 48.0 0.417 0.0 HOH
 2.931
 N
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ALA A:109 A:109 48.0 0.417 S -70.7 154.5 48.0 0.417 0.0 HOH
 3.094
 N
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 ALA A:109 A:109 49.0 0.426 S -65.6 151.3 49.0 0.426 0.0 HOH
 3.657
 C
 O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ALA A:109 A:109 49.0 0.426 -76.4 153.6 49.0 0.426 0.0 HOH
 6.461
 CB
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 ALA A:109 A:109 48.0 0.417 S -64.8 157.2 48.0 0.417 0.0 HOH
 9.629
 O
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 ALA A:109 A:109 48.0 0.417 S -72.6 151.1 48.0 0.417 0.0 HOH
 4.525
 CB
 O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 ALA A:109 A:109 47.0 0.409 S -60.9 157.9 47.0 0.409 0.0 GLC
HOH
 9.576
2.948
 N
N
 O2
O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ALA A:109 A:109 49.0 0.426 -71.0 154.4 49.0 0.426 0.0 HOH
 5.036
 CA
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 ALA A:109 A:109 48.0 0.417 S -72.8 154.4 48.0 0.417 0.0 HOH
 3.554
 C
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 ALA A:109 A:109 48.0 0.417 -71.8 152.2 48.0 0.417 0.0 HOH
 3.012
 N
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 ALA A:109 A:109 47.0 0.409 -73.1 156.0 47.0 0.409 0.0 HOH
 4.156
 O
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 ALA A:109 A:109 48.0 0.417 -67.2 156.2 48.0 0.417 0.0 HOH
 2.835
 N
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 ALA A:109 A:109 49.0 0.426 S -65.6 156.4 49.0 0.426 0.0 HOH
 2.741
 N
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 ALA A:109 A:109 50.0 0.435 S -64.8 154.4 50.0 0.435 0.0 HOH
 2.995
 N
 O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 ALA A:109 A:109 44.0 0.383 S -59.8 152.9 44.0 0.383 0.0 HOH
 9.897
 CA
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 ALA A:109 A:109 46.0 0.4 -69.7 147.5 46.0 0.4 0.0 HOH
 3.563
 CB
 O
ALA B:109 B:109 47.0 0.409 -69.6 147.5 47.0 0.409 0.0 HOH
 3.562
 CB
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 ALA A:109 X:109 43.0 0.374 S -65.4 154.1 43.0 0.374 0.0 HOH
 2.938
 N
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 ALA A:109 X:109 50.0 0.435 S -65.9 153.3 50.0 0.435 0.0 HOH
 3.105
 N
 O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 ALA A:109 A:109 48.0 0.417 S -67.5 153.4 48.0 0.417 0.0 HOH
 2.915
 N
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 ALA A:109 A:109 49.0 0.426 S -68.1 151.3 49.0 0.426 0.0 HOH
 2.979
 N
 O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 ALA A:109 A:109 49.0 0.426 S -65.4 153.5 49.0 0.426 0.0 HOH
 2.907
 N
 O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 ALA A:109 X:109 48.0 0.417 S -67.5 151.5 48.0 0.417 0.0 HOH
 2.947
 N
 O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 ALA A:109 A:109 48.0 0.417 S -70.9 155.1 48.0 0.417 0.0 HOH
 2.802
 N
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 ALA A:109 A:109 48.0 0.417 S -63.2 154.3 48.0 0.417 0.0 HOH
 2.875
 N
 O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 ALA A:109 A:109 51.0 0.443 S -67.0 150.6 51.0 0.443 0.0 HOH
 2.939
 N
 O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ALA A:109 A:109 52.0 0.452 S -73.9 142.4 52.0 0.452 0.0 HOH
 2.772
 O
 O
ALA B:109 B:109 49.0 0.426 S -72.4 148.4 NA NA NA
ALA C:109 C:109 50.0 0.435 S -69.8 140.4 NA NA NA
ALA D:109 D:109 51.0 0.443 S -79.6 148.8 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ALA A:109 A:109 57.0 0.496 S -79.8 153.5 57.0 0.496 0.0 HOH
 2.476
 N
 O
ALA C:109 C:109 49.0 0.426 -77.0 153.0 NA NA NA
ALA E:109 E:109 51.0 0.443 -77.5 157.1 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 ALA A:109 A:109 52.0 0.452 S -73.5 148.7 52.0 0.452 0.0 HOH
 3.540
 C
 O
ALA B:109 B:109 51.0 0.443 S -72.9 148.8 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 ALA A:109 A:109 50.0 0.435 S -69.3 145.4 50.0 0.435 0.0 HOH
 1.432
 H
 H1
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 ALA A:109 A:109 53.0 0.461 S -65.1 146.6 53.0 0.461 0.0 HOH
 3.585
 O
 O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 ALA A:109 A:109 50.0 0.435 S -69.9 139.0 50.0 0.435 0.0 GLC
GLC
GLC
HOH
 6.261
9.386
9.067
2.163
 H
O
N
H
 H1
HO2
H62
O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 ALA A:109 A:109 50.0 0.435 S -75.0 145.9 50.0 0.435 0.0 GLC
GLC
GLC
HOH
 9.277
8.458
6.627
2.182
 O
N
N
H
 HO2
O3
O2
O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 ALA A:109 A:109 52.0 0.452 S -79.2 145.4 52.0 0.452 0.0 HOH
 2.795
 N
 O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 ALA A:109 A:109 54.0 0.47 S -77.1 146.3 54.0 0.47 0.0
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 ALA A:109 A:109 53.0 0.461 -86.6 140.4 53.0 0.461 0.0 HG
HOH
 6.750
5.093
 CA
CB
 HG
O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 ALA A:109 A:109 52.0 0.452 S -66.9 143.3 52.0 0.452 0.0 HOH
 3.860
 C
 O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 ALA A:109 A:109 51.0 0.443 -85.0 147.1 51.0 0.443 0.0 EDO
HOH
 3.448
2.709
 C
O
 C1
O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 ALA A:109 A:109 51.0 0.443 S -82.9 143.6 51.0 0.443 0.0 EDO
HOH
 9.305
3.007
 N
N
 O2
O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 ALA A:109 P:109 55.0 0.478 S -85.5 127.1 55.0 0.478 0.0 HOH
 3.573
 N
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 ALA A:109 A:109 49.0 0.426 S -65.8 142.5 49.0 0.426 0.0 HOH
 3.714
 N
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 ALA A:109 A:109 52.0 0.452 S -72.0 146.0 52.0 0.452 0.0 HOH
 3.592
 N
 O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 ALA A:109 A:109 50.0 0.435 S -83.8 147.1 50.0 0.435 0.0 HOH
 3.148
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 ALA A:124 A:124 49.0 0.426 S -62.1 149.2
af-p04746-f1 1 P04746 98.83 0.0 ALA A:124 A:124 51.0 0.443 S -62.4 149.2
af-p0dte7-f1 1 P0DTE7 97.46 0.0 ALA A:124 A:124 48.0 0.417 S -62.7 149.8
af-p0dte8-f1 1 P0DTE8 97.46 0.0 ALA A:124 A:124 48.0 0.417 S -62.6 150.0
af-p0dub6-f1 1 P0DUB6 97.46 0.0 ALA A:124 A:124 48.0 0.417 S -63.1 151.0