Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104116405 . T A CCDS782.1:NM_020978.4:c.589Tat>Aat_NP_066188.1:p.197Y>N Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 TYR A:182 A:182 6.0 0.026 H -65.3 -52.6 6.0 0.026 0.0 HOH
 2.657
 OH
 O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 TYR A:182 A:182 5.0 0.022 H -64.3 -50.1 5.0 0.022 0.0 HOH
 2.717
 OH
 O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 TYR A:182 A:182 6.0 0.026 H -62.0 -49.8 6.0 0.026 0.0 HOH
 2.728
 OH
 O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 TYR A:182 A:182 6.0 0.026 H -64.8 -50.6 6.0 0.026 0.0 HOH
 2.697
 OH
 O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 TYR A:182 A:182 5.0 0.022 H -61.6 -49.1 5.0 0.022 0.0 HOH
 2.699
 OH
 O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 TYR A:182 A:182 6.0 0.026 H -61.1 -53.6 6.0 0.026 0.0 HOH
 2.494
 OH
 O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 TYR A:182 A:182 9.0 0.039 H -65.2 -51.0 9.0 0.039 0.0 HOH
 2.800
 OH
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 TYR A:182 A:182 7.0 0.03 H -67.2 -49.1 7.0 0.03 0.0 HOH
 2.812
 OH
 O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 TYR A:182 A:182 6.0 0.026 H -61.7 -54.1 6.0 0.026 0.0 HOH
 2.688
 OH
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 TYR A:182 A:182 8.0 0.035 H -63.7 -48.5 8.0 0.035 0.0 HOH
 2.744
 OH
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 TYR A:182 A:182 10.0 0.043 H -65.2 -50.8 10.0 0.043 0.0 HOH
 2.766
 OH
 O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 TYR A:182 A:182 7.0 0.03 H -63.4 -50.7 7.0 0.03 0.0 HOH
 2.818
 OH
 O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 TYR A:182 A:182 8.0 0.035 H -58.5 -50.8 8.0 0.035 0.0 HOH
 2.758
 OH
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 TYR A:182 A:182 8.0 0.035 H -66.5 -48.6 8.0 0.035 0.0 HOH
 2.837
 OH
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 TYR A:182 A:182 5.0 0.022 H -65.5 -52.8 5.0 0.022 0.0 HOH
 2.806
 OH
 O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 TYR A:182 A:182 8.0 0.035 H -61.9 -50.0 8.0 0.035 0.0 HOH
 2.861
 OH
 O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 TYR A:182 A:182 6.0 0.026 H -69.1 -48.3 6.0 0.026 0.0 HOH
 2.590
 OH
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 TYR A:182 A:182 6.0 0.026 H -70.7 -47.0 6.0 0.026 0.0 HOH
 2.754
 OH
 O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 TYR A:182 A:182 8.0 0.035 H -63.9 -51.6 8.0 0.035 0.0 HOH
 2.861
 OH
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 TYR A:182 A:182 8.0 0.035 H -61.4 -49.9 8.0 0.035 0.0 HOH
 2.808
 OH
 O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 TYR A:182 A:182 9.0 0.039 H -64.6 -47.3 9.0 0.039 0.0 HOH
 2.643
 OH
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 TYR A:182 A:182 6.0 0.026 H -67.3 -48.2 6.0 0.026 0.0 HOH
 2.654
 OH
 O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 TYR A:182 A:182 5.0 0.022 H -64.5 -50.3 5.0 0.022 0.0 HOH
 2.708
 OH
 O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 TYR A:182 A:182 5.0 0.022 H -66.6 -48.7 5.0 0.022 0.0 HOH
 2.690
 OH
 O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 TYR A:182 A:182 9.0 0.039 H -63.4 -47.0 9.0 0.039 0.0 HOH
 2.655
 OH
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 TYR A:182 A:182 6.0 0.026 H -65.6 -49.9 6.0 0.026 0.0 HOH
 2.703
 OH
 O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 TYR A:182 A:182 5.0 0.022 H -61.4 -51.1 5.0 0.022 0.0 HOH
 2.761
 OH
 O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 TYR A:182 A:182 5.0 0.022 H -60.0 -51.6 5.0 0.022 0.0 HOH
 1.956
 HH
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 TYR A:182 A:182 5.0 0.022 H -58.6 -51.3 5.0 0.022 0.0 HOH
 1.941
 HH
 O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 TYR A:182 A:182 5.0 0.022 H -60.8 -51.4 5.0 0.022 0.0 HOH
 2.681
 HD1
 O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 TYR A:182 A:182 5.0 0.022 H -61.4 -50.7 5.0 0.022 0.0 HOH
 2.710
 OH
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 TYR A:182 A:182 6.0 0.026 H -59.7 -51.5 6.0 0.026 0.0 HOH
 2.664
 HD1
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 TYR A:182 A:182 6.0 0.026 H -59.9 -52.1 6.0 0.026 0.0 HOH
 2.709
 OH
 O
TYR B:182 B:182 7.0 0.03 H -60.7 -53.2 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 TYR A:182 A:182 6.0 0.026 H -61.7 -50.7 6.0 0.026 0.0 HOH
 2.726
 OH
 O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 TYR A:182 A:182 6.0 0.026 H -61.0 -51.3 6.0 0.026 0.0 HOH
 2.703
 OH
 O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 TYR A:182 A:182 8.0 0.035 H -65.1 -50.4 8.0 0.035 0.0 HOH
 2.704
 OH
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 TYR A:182 A:182 8.0 0.035 H -63.2 -49.3 8.0 0.035 0.0 HOH
 2.830
 OH
 O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 TYR A:182 A:182 8.0 0.035 H -63.8 -52.2 8.0 0.035 0.0 HOH
 2.829
 OH
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 TYR A:182 A:182 9.0 0.039 H -67.1 -50.0 9.0 0.039 0.0 HOH
 2.735
 OH
 O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 TYR A:182 A:182 10.0 0.043 H -64.8 -50.5 10.0 0.043 0.0 HOH
 2.743
 OH
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 TYR A:182 A:182 9.0 0.039 H -66.0 -48.1 9.0 0.039 0.0 HOH
 2.663
 OH
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 TYR A:182 A:182 9.0 0.039 H -64.2 -55.6 9.0 0.039 0.0 HOH
 2.810
 OH
 O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 TYR A:182 A:182 7.0 0.03 H -70.8 -42.6 7.0 0.03 0.0 HOH
 2.811
 OH
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 TYR A:182 A:182 8.0 0.035 H -66.7 -48.8 8.0 0.035 0.0 HOH
 2.746
 OH
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 TYR A:182 A:182 7.0 0.03 H -63.5 -49.9 7.0 0.03 0.0 HOH
 2.883
 OH
 O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 TYR A:182 A:182 6.0 0.026 H -59.8 -50.4 6.0 0.026 0.0 HOH
 2.749
 OH
 O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 TYR A:182 A:182 9.0 0.039 H -70.3 -45.4 9.0 0.039 0.0 HOH
 2.777
 OH
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 TYR A:182 A:182 7.0 0.03 H -64.4 -49.8 7.0 0.03 0.0 HOH
 2.818
 OH
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 TYR A:182 A:182 7.0 0.03 H -70.3 -46.0 7.0 0.03 0.0 HOH
 2.755
 OH
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 TYR A:182 A:182 9.0 0.039 H -67.7 -46.9 9.0 0.039 0.0 HOH
 2.778
 OH
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 TYR A:182 A:182 10.0 0.043 H -66.3 -49.7 10.0 0.043 0.0 HOH
 2.743
 OH
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 TYR A:182 A:182 5.0 0.022 H -62.9 -51.0 5.0 0.022 0.0 HOH
 2.794
 OH
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 TYR A:182 A:182 4.0 0.017 H -55.8 -51.8 4.0 0.017 0.0 HOH
 2.707
 OH
 O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 TYR A:182 A:182 8.0 0.035 H -60.1 -54.7 8.0 0.035 0.0 HOH
 2.618
 OH
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 TYR A:182 A:182 6.0 0.026 H -62.1 -54.9 6.0 0.026 0.0 HOH
 2.579
 OH
 O
TYR B:182 B:182 7.0 0.03 H -62.1 -54.9 7.0 0.03 0.0 HOH
 2.580
 OH
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 TYR A:182 X:182 4.0 0.017 H -61.0 -49.1 4.0 0.017 0.0 HOH
 2.639
 OH
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 TYR A:182 X:182 4.0 0.017 H -63.5 -49.1 4.0 0.017 0.0 HOH
 2.746
 OH
 O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 TYR A:182 A:182 5.0 0.022 H -61.9 -44.8 5.0 0.022 0.0 HOH
 2.712
 OH
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 TYR A:182 A:182 5.0 0.022 H -59.1 -51.5 5.0 0.022 0.0 HOH
 2.717
 OH
 O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 TYR A:182 A:182 5.0 0.022 H -61.7 -51.8 5.0 0.022 0.0 HOH
 2.813
 OH
 O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 TYR A:182 X:182 5.0 0.022 H -60.5 -52.1 5.0 0.022 0.0 HOH
 2.741
 OH
 O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 TYR A:182 A:182 6.0 0.026 H -60.8 -52.0 6.0 0.026 0.0 HOH
 2.789
 OH
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 TYR A:182 A:182 5.0 0.022 H -59.2 -51.7 5.0 0.022 0.0 HOH
 2.643
 OH
 O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 TYR A:182 A:182 5.0 0.022 H -59.5 -50.4 5.0 0.022 0.0 HOH
 2.689
 OH
 O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 TYR A:182 A:182 4.0 0.017 H -65.0 -50.7 4.0 0.017 0.0 HOH
 2.693
 OH
 O
TYR B:182 B:182 4.0 0.017 H -65.3 -49.9 NA NA NA
TYR C:182 C:182 4.0 0.017 H -65.6 -47.0 NA NA NA
TYR D:182 D:182 8.0 0.035 H -65.6 -49.9 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 TYR A:182 A:182 4.0 0.017 H -64.9 -50.5 4.0 0.017 0.0 HOH
 3.125
 OH
 O
TYR C:182 C:182 3.0 0.013 H -62.8 -54.9 NA NA NA
TYR E:182 E:182 2.0 0.009 H -63.4 -53.8 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 TYR A:182 A:182 4.0 0.017 H -63.2 -52.0 4.0 0.017 0.0 HOH
 2.646
 OH
 O
TYR B:182 B:182 4.0 0.017 H -65.8 -50.2 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 TYR A:182 A:182 6.0 0.026 H -63.6 -52.0 6.0 0.026 0.0 HOH
 1.239
 HH
 H1
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 TYR A:182 A:182 5.0 0.022 H -65.7 -46.6 5.0 0.022 0.0 HOH
 2.882
 OH
 O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 TYR A:182 A:182 10.0 0.043 H -66.1 -51.4 10.0 0.043 0.0 HOH
 1.992
 HH
 O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 TYR A:182 A:182 8.0 0.035 H -63.8 -50.4 8.0 0.035 0.0 HOH
 2.062
 HH
 O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 TYR A:182 A:182 10.0 0.043 H -58.8 -53.8 10.0 0.043 0.0 HOH
 2.687
 OH
 O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 TYR A:182 A:182 9.0 0.039 H -70.6 -46.6 9.0 0.039 0.0 HOH
 2.756
 OH
 O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 TYR A:182 A:182 6.0 0.026 H -68.4 -45.0 6.0 0.026 0.0 HOH
 2.860
 OH
 O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 TYR A:182 A:182 10.0 0.043 H -67.1 -49.1 10.0 0.043 0.0 HOH
 2.749
 OH
 O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 TYR A:182 A:182 7.0 0.03 H -62.3 -51.2 7.0 0.03 0.0 HOH
 2.692
 OH
 O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 TYR A:182 A:182 8.0 0.035 H -64.1 -48.4 8.0 0.035 0.0 HOH
 2.651
 OH
 O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 TYR A:182 P:182 11.0 0.048 H -58.0 -52.9 11.0 0.048 0.0 HOH
 4.713
 N
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 TYR A:182 A:182 8.0 0.035 H -62.0 -54.7 8.0 0.035 0.0 HOH
 2.891
 OH
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 TYR A:182 A:182 9.0 0.039 H -63.1 -51.5 9.0 0.039 0.0 HOH
 3.735
 CA
 O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 TYR A:182 A:182 8.0 0.035 H -62.3 -52.0 8.0 0.035 0.0 HOH
 2.796
 OH
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 TYR A:197 A:197 7.0 0.03 H -58.8 -47.4
af-p04746-f1 1 P04746 98.83 0.0 TYR A:197 A:197 8.0 0.035 H -58.2 -48.1
af-p0dte7-f1 1 P0DTE7 97.46 0.0 TYR A:197 A:197 9.0 0.039 H -59.2 -47.4
af-p0dte8-f1 1 P0DTE8 97.46 0.0 TYR A:197 A:197 8.0 0.035 H -59.1 -47.3
af-p0dub6-f1 1 P0DUB6 97.46 0.0 TYR A:197 A:197 8.0 0.035 H -59.3 -48.3