Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104116483 . A C CCDS782.1:NM_020978.4:c.667Aag>Cag_NP_066188.1:p.223K>Q Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 LYS A:208 A:208 102.0 0.51 H -57.1 -42.3 102.0 0.51 0.0 PCA
HOH
 9.143
2.677
 CG
NZ
 CG
O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 LYS A:208 A:208 103.0 0.515 H -57.6 -41.8 103.0 0.515 0.0 PCA
HOH
 9.097
2.905
 CG
CG
 CG
O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 LYS A:208 A:208 105.0 0.525 H -56.6 -43.5 105.0 0.525 0.0 BGC
PCA
HOH
 7.765
9.119
4.298
 CB
CG
CB
 O6
CG
O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 LYS A:208 A:208 124.0 0.62 H -56.8 -43.5 124.0 0.62 0.0 GLC
PCA
HOH
 6.351
9.156
2.791
 CE
CG
O
 O6
CG
O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 LYS A:208 A:208 101.0 0.505 H -52.8 -49.3 101.0 0.505 0.0 GLC
HOH
 6.417
2.193
 HB3
HZ2
 O6
O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 LYS A:208 A:208 111.0 0.555 H -56.4 -46.8 111.0 0.555 0.0 PCA
HOH
 9.262
4.668
 CG
NZ
 CG
O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 LYS A:208 A:208 70.0 0.35 H -58.5 -39.0 70.0 0.35 0.0 HOH
 3.184
 CE
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 LYS A:208 A:208 78.0 0.39 H -57.3 -43.2 78.0 0.39 0.0 HOH
 2.912
 NZ
 O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 LYS A:208 A:208 108.0 0.54 H -52.2 -49.4 108.0 0.54 0.0 HOH
 3.095
 NZ
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 LYS A:208 A:208 74.0 0.37 H -57.1 -42.8 74.0 0.37 0.0 HOH
 4.144
 CB
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 LYS A:208 A:208 77.0 0.385 H -58.7 -36.3 77.0 0.385 0.0 HOH
 3.753
 NZ
 O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 LYS A:208 A:208 91.0 0.455 H -56.8 -45.8 91.0 0.455 0.0 HOH
 2.730
 NZ
 O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 LYS A:208 A:208 80.0 0.4 H -59.3 -40.5 80.0 0.4 0.0 HOH
 3.380
 NZ
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 LYS A:208 A:208 71.0 0.355 H -57.9 -43.8 71.0 0.355 0.0 HOH
 3.905
 NZ
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 LYS A:208 A:208 80.0 0.4 H -57.9 -42.7 80.0 0.4 0.0 HOH
 4.157
 CB
 O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 LYS A:208 A:208 82.0 0.41 H -56.6 -39.7 82.0 0.41 0.0 HOH
 3.895
 CB
 O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 LYS A:208 A:208 104.0 0.52 H -52.1 -55.4 104.0 0.52 0.0 HOH
 2.696
 NZ
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 LYS A:208 A:208 106.0 0.53 H -57.5 -44.6 106.0 0.53 0.0 HOH
 3.353
 CD
 O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 LYS A:208 A:208 70.0 0.35 H -57.0 -43.1 70.0 0.35 0.0 HOH
 2.896
 CE
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 LYS A:208 A:208 73.0 0.365 H -57.8 -40.5 73.0 0.365 0.0 HOH
 3.862
 CB
 O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 LYS A:208 A:208 101.0 0.505 H -55.9 -43.1 101.0 0.505 0.0 HOH
 3.464
 O
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 LYS A:208 A:208 74.0 0.37 H -59.5 -40.4 74.0 0.37 0.0 HOH
 4.380
 CB
 O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 LYS A:208 A:208 69.0 0.345 H -59.8 -42.6 69.0 0.345 0.0 B0D
B0D
HOH
 7.309
3.597
2.831
 N
CD
NZ
 F2
F1
O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 LYS A:208 A:208 73.0 0.365 H -58.1 -44.0 73.0 0.365 0.0 B0D
B0D
HOH
 7.337
3.641
2.928
 N
CD
NZ
 F2
F1
O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 LYS A:208 A:208 77.0 0.385 H -65.3 -35.9 77.0 0.385 0.0 HOH
 2.722
 NZ
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 LYS A:208 A:208 78.0 0.39 H -57.0 -43.6 78.0 0.39 0.0 HOH
 2.697
 NZ
 O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 LYS A:208 A:208 110.0 0.55 H -56.6 -45.5 110.0 0.55 0.0 HOH
 3.604
 CG
 O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 LYS A:208 A:208 79.0 0.395 H -58.0 -43.0 79.0 0.395 0.0 HOH
 2.168
 HZ1
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 LYS A:208 A:208 108.0 0.54 H -51.6 -49.3 108.0 0.54 0.0 HOH
 2.736
 HG3
 O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 LYS A:208 A:208 114.0 0.57 H -56.7 -42.8 114.0 0.57 0.0 HOH
 2.460
 HD2
 O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 LYS A:208 A:208 110.0 0.55 H -57.9 -41.9 110.0 0.55 0.0 HOH
 3.699
 CD
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 LYS A:208 A:208 71.0 0.355 H -57.8 -43.0 71.0 0.355 0.0 HOH
 1.915
 HZ1
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 LYS A:208 A:208 121.0 0.605 H -56.1 -44.0 121.0 0.605 0.0 HOH
 5.043
 O
 O
LYS B:208 B:208 89.0 0.445 H -55.7 -44.3 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 LYS A:208 A:208 74.0 0.37 H -56.8 -44.0 74.0 0.37 0.0 HOH
 2.124
 HZ1
 O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 LYS A:208 A:208 72.0 0.36 H -57.8 -43.0 72.0 0.36 0.0 HOH
 1.911
 HZ1
 O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 LYS A:208 A:208 76.0 0.38 H -56.5 -42.9 76.0 0.38 0.0 HOH
 3.534
 CE
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 LYS A:208 A:208 73.0 0.365 H -58.5 -42.5 73.0 0.365 0.0 HOH
 3.512
 CE
 O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 LYS A:208 A:208 78.0 0.39 H -59.0 -43.7 78.0 0.39 0.0 HOH
 2.928
 CG
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 LYS A:208 A:208 78.0 0.39 H -62.3 -40.9 78.0 0.39 0.0 HOH
 2.828
 CD
 O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 LYS A:208 A:208 70.0 0.35 H -55.8 -41.8 70.0 0.35 0.0 HOH
 2.614
 NZ
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 LYS A:208 A:208 101.0 0.505 H -56.3 -43.6 101.0 0.505 0.0 HOH
 3.196
 CG
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 LYS A:208 A:208 69.0 0.345 H -51.3 -39.2 69.0 0.345 0.0 HOH
 2.627
 NZ
 O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 LYS A:208 A:208 76.0 0.38 H -58.5 -44.6 76.0 0.38 0.0 HOH
 2.957
 CG
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 LYS A:208 A:208 67.0 0.335 H -58.9 -44.3 67.0 0.335 0.0 HOH
 4.272
 CB
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 LYS A:208 A:208 76.0 0.38 H -62.8 -43.3 76.0 0.38 0.0 HOH
 4.490
 CB
 O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 LYS A:208 A:208 106.0 0.53 H -56.2 -47.0 106.0 0.53 0.0 GLC
HOH
 7.487
2.729
 CB
NZ
 O6
O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 LYS A:208 A:208 73.0 0.365 H -57.1 -45.6 73.0 0.365 0.0 HOH
 2.918
 CD
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 LYS A:208 A:208 108.0 0.54 H -60.6 -43.8 108.0 0.54 0.0 HOH
 5.655
 O
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 LYS A:208 A:208 108.0 0.54 H -57.6 -43.1 108.0 0.54 0.0 HOH
 2.785
 NZ
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 LYS A:208 A:208 73.0 0.365 H -56.4 -45.0 73.0 0.365 0.0 HOH
 4.246
 CD
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 LYS A:208 A:208 73.0 0.365 H -55.6 -44.9 73.0 0.365 0.0 HOH
 3.317
 CE
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 LYS A:208 A:208 110.0 0.55 H -54.9 -54.4 110.0 0.55 0.0 HOH
 3.529
 NZ
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 LYS A:208 A:208 120.0 0.6 H -55.1 -46.3 120.0 0.6 0.0 HOH
 4.151
 CG
 O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 LYS A:208 A:208 108.0 0.54 H -57.5 -45.1 108.0 0.54 0.0 HOH
 2.940
 NZ
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 LYS A:208 A:208 106.0 0.53 H -62.8 -53.5 106.0 0.53 0.0 HOH
 3.093
 CG
 O
LYS B:208 B:208 106.0 0.53 H -62.8 -53.5 106.0 0.53 0.0 HOH
 3.093
 CG
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 LYS A:208 X:208 110.0 0.55 H -47.5 -47.9 110.0 0.55 0.0 HOH
 3.308
 CG
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 LYS A:208 X:208 126.0 0.63 H -55.1 -46.0 126.0 0.63 0.0 HOH
 3.347
 NZ
 O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 LYS A:208 A:208 110.0 0.55 H -49.3 -50.0 110.0 0.55 0.0 HOH
 4.476
 CB
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 LYS A:208 A:208 108.0 0.54 H -55.7 -49.2 108.0 0.54 0.0 HOH
 3.266
 CG
 O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 LYS A:208 A:208 111.0 0.555 H -54.8 -48.1 111.0 0.555 0.0 HOH
 3.492
 NZ
 O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 LYS A:208 X:208 107.0 0.535 H -53.4 -46.9 107.0 0.535 0.0 HOH
 3.339
 O
 O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 LYS A:208 A:208 115.0 0.575 H -52.0 -46.6 115.0 0.575 0.0 HOH
 3.408
 CG
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 LYS A:208 A:208 112.0 0.56 H -52.9 -48.9 112.0 0.56 0.0 GLC
HOH
 7.534
3.218
 CB
CG
 O6
O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 LYS A:208 A:208 107.0 0.535 H -55.8 -40.9 107.0 0.535 0.0 HOH
 3.307
 O
 O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 LYS A:208 A:208 82.0 0.41 H -56.4 -43.7 82.0 0.41 0.0 HOH
 3.318
 CE
 O
LYS B:208 B:208 80.0 0.4 H -56.7 -47.0 NA NA NA
LYS C:208 C:208 78.0 0.39 H -59.1 -44.2 NA NA NA
LYS D:208 D:208 81.0 0.405 H -58.1 -45.1 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 LYS A:208 A:208 78.0 0.39 H -52.1 -50.1 78.0 0.39 0.0 HOH
 2.526
 NZ
 O
LYS C:208 C:208 83.0 0.415 H -59.6 -44.8 NA NA NA
LYS E:208 E:208 82.0 0.41 H -55.5 -48.0 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 LYS A:208 A:208 75.0 0.375 H -58.8 -37.9 24.0 0.12 0.255 C:None:0.255
 HOH
 2.732
 CE
 O
LYS B:208 B:208 91.0 0.455 H -61.0 -35.8 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 LYS A:208 A:208 83.0 0.415 H -56.6 -43.0 83.0 0.415 0.0 HOH
 3.678
 CB
 H1
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 LYS A:208 A:208 83.0 0.415 H -55.7 -42.7 83.0 0.415 0.0 HOH
 3.737
 CG
 O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 LYS A:208 A:208 85.0 0.425 H -55.7 -43.3 85.0 0.425 0.0 HOH
 4.539
 O
 O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 LYS A:208 A:208 82.0 0.41 H -57.0 -42.8 82.0 0.41 0.0 HOH
 5.018
 O
 O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 LYS A:208 A:208 87.0 0.435 H -54.5 -42.4 87.0 0.435 0.0 CL
BGC
HOH
 7.319
7.214
3.071
 CB
CB
CE
 CL
O6
O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 LYS A:208 A:208 76.0 0.38 H -60.8 -40.4 76.0 0.38 0.0 HOH
 5.164
 NZ
 O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 LYS A:208 A:208 85.0 0.425 H -57.4 -39.2 85.0 0.425 0.0 HOH
 3.631
 CB
 O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 LYS A:208 A:208 74.0 0.37 H -58.1 -47.7 74.0 0.37 0.0 HOH
 3.328
 NZ
 O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 LYS A:208 A:208 105.0 0.525 H -56.0 -42.4 105.0 0.525 0.0 CL
EDO
HOH
 7.702
6.554
3.065
 CB
O
CG
 CL
O2
O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 LYS A:208 A:208 82.0 0.41 H -57.8 -43.0 82.0 0.41 0.0 EDO
HOH
 6.065
3.609
 O
CE
 O1
O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 LYS A:208 P:208 93.0 0.465 H -66.3 -41.4 93.0 0.465 0.0 HOH
 5.730
 O
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 LYS A:208 A:208 108.0 0.54 H -62.1 -44.6 108.0 0.54 0.0 HOH
 4.041
 CD
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 LYS A:208 A:208 84.0 0.42 H -55.1 -47.6 84.0 0.42 0.0 HOH
 3.682
 CE
 O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 LYS A:208 A:208 99.0 0.495 H -58.1 -41.9 99.0 0.495 0.0 HOH
 3.652
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 LYS A:223 A:223 73.0 0.365 H -55.1 -46.2
af-p04746-f1 1 P04746 98.83 0.0 LYS A:223 A:223 78.0 0.39 H -54.7 -46.9
af-p0dte7-f1 1 P0DTE7 97.46 0.0 LYS A:223 A:223 74.0 0.37 H -54.3 -46.4
af-p0dte8-f1 1 P0DTE8 97.46 0.0 LYS A:223 A:223 71.0 0.355 H -54.0 -46.5
af-p0dub6-f1 1 P0DUB6 97.46 0.0 LYS A:223 A:223 65.0 0.325 H -54.1 -46.2