Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104166590 . C A CCDS783.1:NM_000699.2:c.1204Cga>Aga_NP_000690.1:p.402R>R Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 ARG A:387 A:387 14.0 0.062 G -98.2 -8.7 14.0 0.062 0.0 HOH
 2.754
 NH1
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 ARG A:387 A:387 14.0 0.062 G -100.5 -3.4 14.0 0.062 0.0 HOH
 2.715
 O
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 ARG A:387 A:387 12.0 0.053 G -98.2 -5.6 12.0 0.053 0.0 HOH
 2.638
 O
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 ARG A:387 A:387 12.0 0.053 G -95.4 -5.9 12.0 0.053 0.0 HOH
 2.620
 O
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ARG A:387 A:387 14.0 0.062 G -100.6 -11.1 14.0 0.062 0.0 HOH
 2.675
 O
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ARG A:387 A:387 11.0 0.049 G -93.4 -9.1 11.0 0.049 0.0 HOH
 2.507
 O
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ARG A:387 A:387 12.0 0.053 G -95.0 -13.6 12.0 0.053 0.0 HOH
 2.814
 O
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ARG A:387 A:387 15.0 0.067 G -99.2 -9.2 15.0 0.067 0.0 HOH
 2.644
 O
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ARG A:387 A:387 15.0 0.067 G -99.2 -7.6 15.0 0.067 0.0 HOH
 2.714
 O
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ARG A:387 A:387 13.0 0.058 G -97.1 -8.7 13.0 0.058 0.0 HOH
 2.650
 O
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ARG A:387 A:387 14.0 0.062 G -100.2 -3.5 14.0 0.062 0.0 HOH
 2.667
 O
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ARG A:387 A:387 9.0 0.04 G -98.3 -9.9 9.0 0.04 0.0 HOH
 2.576
 O
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ARG A:387 A:387 13.0 0.058 G -93.2 -10.5 13.0 0.058 0.0 HOH
 2.645
 O
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ARG A:387 A:387 14.0 0.062 G -99.0 -8.4 14.0 0.062 0.0 HOH
 2.763
 O
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ARG A:387 A:387 14.0 0.062 G -96.7 -6.3 14.0 0.062 0.0 HOH
 2.604
 O
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ARG A:387 A:387 11.0 0.049 G -98.2 -10.7 11.0 0.049 0.0 HOH
 2.605
 O
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ARG A:387 A:387 12.0 0.053 G -98.9 -7.6 12.0 0.053 0.0 GLF
B8D
HOH
 6.663
3.081
2.658
 O
O
O
 O4
O6
O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ARG A:387 A:387 13.0 0.058 G -97.6 -7.6 13.0 0.058 0.0 HOH
 2.642
 O
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ARG A:387 A:387 10.0 0.044 G -99.1 -6.4 10.0 0.044 0.0 HOH
 2.607
 O
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 ARG A:387 A:387 10.0 0.044 G -96.1 -7.3 10.0 0.044 0.0 0XR
HOH
 8.462
2.613
 NH2
O
 O1'
O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 ARG A:387 A:387 11.0 0.049 G -97.1 -9.9 11.0 0.049 0.0 HOH
 2.652
 O
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 ARG A:387 A:387 10.0 0.044 G -97.8 -6.1 10.0 0.044 0.0 HOH
 2.627
 O
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 ARG A:387 A:387 11.0 0.049 G -97.2 -7.5 11.0 0.049 0.0 HOH
 2.081
 HH12
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 ARG A:387 A:387 13.0 0.058 G -95.1 -8.8 13.0 0.058 0.0 HOH
 2.132
 HH22
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 ARG A:387 A:387 11.0 0.049 G -97.9 -5.4 11.0 0.049 0.0 HOH
 2.095
 HH12
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 ARG A:387 A:387 11.0 0.049 G -95.5 -3.1 11.0 0.049 0.0 HOH
 2.703
 O
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 ARG A:387 A:387 12.0 0.053 G -97.1 -8.0 12.0 0.053 0.0 HOH
 2.071
 HH12
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 ARG A:387 A:387 10.0 0.044 G -95.5 -8.7 10.0 0.044 0.0 HOH
 3.764
 O
 O
ARG B:387 B:387 10.0 0.044 G -95.1 -7.9 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 ARG A:387 A:387 11.0 0.049 G -95.0 -7.2 11.0 0.049 0.0 HOH
 2.064
 HH12
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 ARG A:387 A:387 11.0 0.049 G -97.0 -7.9 11.0 0.049 0.0 HOH
 2.085
 HH12
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ARG A:387 A:387 14.0 0.062 G -103.8 -2.8 14.0 0.062 0.0 BGC
GLC
GLC
HOH
 9.947
6.184
2.975
2.819
 C
O
O
NH2
 O4
C6
O6
O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ARG A:387 A:387 13.0 0.058 G -102.2 -6.6 13.0 0.058 0.0 BGC
GLC
GLC
HOH
 9.774
6.075
3.197
2.650
 C
O
O
O
 O4
C6
O6
O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ARG A:387 A:387 11.0 0.049 G -99.1 -6.5 11.0 0.049 0.0 GLC
HOH
 6.043
2.647
 O
O
 C6
O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ARG A:387 A:387 12.0 0.053 G -101.3 -6.0 12.0 0.053 0.0 BGC
MPD
HOH
 6.061
3.228
2.667
 O
O
O
 C6
O2
O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ARG A:387 A:387 14.0 0.062 G -97.4 -6.4 14.0 0.062 0.0 HOH
 2.617
 O
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ARG A:387 A:387 16.0 0.071 G -99.8 -7.6 16.0 0.071 0.0 HOH
 2.667
 O
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ARG A:387 A:387 16.0 0.071 G -98.8 -5.7 16.0 0.071 0.0 HOH
 2.596
 O
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ARG A:387 A:387 16.0 0.071 G -99.9 -9.1 16.0 0.071 0.0 HOH
 2.786
 O
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ARG A:387 A:387 16.0 0.071 G -97.5 -8.7 16.0 0.071 0.0 HOH
 2.717
 O
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ARG A:387 A:387 15.0 0.067 G -96.9 -6.8 15.0 0.067 0.0 HOH
 2.684
 O
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ARG A:387 A:387 10.0 0.044 G -96.9 -9.8 10.0 0.044 0.0 HOH
 2.509
 O
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ARG A:387 A:387 13.0 0.058 G -96.0 -6.9 13.0 0.058 0.0 HOH
 2.675
 O
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ARG A:387 A:387 14.0 0.062 G -99.2 -9.2 14.0 0.062 0.0 HOH
 4.560
 O
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 ARG A:387 A:387 13.0 0.058 G -96.2 -7.4 13.0 0.058 0.0 HOH
 2.103
 HH22
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ARG A:387 A:387 13.0 0.058 G -99.8 -6.4 13.0 0.058 0.0 HOH
 2.686
 O
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 ARG A:387 A:387 13.0 0.058 G -99.5 -4.3 13.0 0.058 0.0 HOH
 2.602
 O
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 ARG A:387 A:387 20.0 0.089 G -100.7 -9.7 20.0 0.089 0.0 HOH
 2.975
 O
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 ARG A:387 A:387 11.0 0.049 G -99.5 -11.4 11.0 0.049 0.0 HOH
 2.649
 O
 O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 ARG A:387 A:387 15.0 0.067 G -98.6 -5.8 15.0 0.067 0.0 HOH
 2.713
 O
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 ARG A:387 A:387 16.0 0.071 G -100.2 -4.6 16.0 0.071 0.0 HOH
 2.731
 O
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 ARG A:387 A:387 16.0 0.071 G -100.1 -9.2 16.0 0.071 0.0 HOH
 2.585
 O
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 ARG A:387 A:387 14.0 0.062 G -97.4 -15.6 14.0 0.062 0.0 HOH
 2.602
 O
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 ARG A:387 A:387 12.0 0.053 G -97.7 -6.4 12.0 0.053 0.0 HOH
 2.581
 O
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 ARG A:387 A:387 11.0 0.049 G -97.1 -8.4 11.0 0.049 0.0 HOH
 2.604
 O
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 ARG A:387 A:387 14.0 0.062 G -99.1 -14.8 14.0 0.062 0.0 HOH
 2.934
 NH1
 O
ARG B:387 B:387 15.0 0.067 G -99.1 -14.8 15.0 0.067 0.0 HOH
 2.934
 NH1
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 ARG A:387 X:387 11.0 0.049 G -97.4 -8.6 11.0 0.049 0.0 HOH
 2.656
 O
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 ARG A:387 A:387 12.0 0.053 G -99.2 -9.5 12.0 0.053 0.0 HOH
 2.686
 O
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 ARG A:387 X:387 14.0 0.062 G -99.3 -9.0 14.0 0.062 0.0 HOH
 2.419
 O
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 ARG A:387 A:387 12.0 0.053 G -99.0 -7.0 12.0 0.053 0.0 HOH
 2.634
 O
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 ARG A:387 A:387 16.0 0.071 G -99.0 -7.8 16.0 0.071 0.0 HOH
 2.614
 O
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 ARG A:387 X:387 17.0 0.076 G -92.9 -11.4 17.0 0.076 0.0 HOH
 2.645
 O
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 ARG A:382 A:382 15.0 0.067 G -98.4 -10.4 15.0 0.067 0.0 HOH
 2.609
 O
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 ARG A:382 A:382 13.0 0.058 G -100.7 -7.5 13.0 0.058 0.0 GLC
GLC
AGL
HMC
HOH
 9.673
5.832
3.466
6.169
2.631
 C
O
O
O
O
 O4
C6
C6
O7
O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 ARG A:387 A:387 18.0 0.08 G -92.2 -8.5 18.0 0.08 0.0 HOH
 2.606
 O
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ARG A:387 A:387 13.0 0.058 G -98.5 -7.2 13.0 0.058 0.0 HOH
 2.522
 O
 O
ARG B:387 B:387 15.0 0.067 G -97.6 -8.4 NA NA NA
ARG C:387 C:387 12.0 0.053 G -99.4 -11.2 NA NA NA
ARG D:387 D:387 11.0 0.049 G -100.5 -8.0 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ARG A:387 A:387 17.0 0.076 G -118.7 2.4 17.0 0.076 0.0 HOH
 2.746
 O
 O
ARG C:387 C:387 13.0 0.058 G -103.4 -1.8 NA NA NA
ARG E:387 E:387 13.0 0.058 G -94.3 -19.5 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ARG A:387 A:387 18.0 0.08 G -95.6 -7.4 18.0 0.08 0.0 HOH
 2.737
 O
 O
ARG B:387 B:387 15.0 0.067 G -96.7 -6.3 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 ARG A:387 A:387 16.0 0.071 G -98.5 -9.0 16.0 0.071 0.0 HOH
 1.982
 O
 H1
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 ARG A:387 A:387 17.0 0.076 G -93.0 -4.6 17.0 0.076 0.0 HOH
 2.726
 NH1
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 ARG A:387 A:387 17.0 0.076 G -99.4 -6.6 17.0 0.076 0.0 HOH
 4.320
 CB
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 ARG A:387 A:387 16.0 0.071 G -100.0 -9.3 16.0 0.071 0.0 HOH
 1.976
 HH22
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 ARG A:387 A:387 18.0 0.08 G -96.5 -9.5 18.0 0.08 0.0 HOH
 2.103
 HH11
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 ARG A:387 A:387 14.0 0.062 G -102.8 -9.1 14.0 0.062 0.0 GLC
GLC
EDO
HOH
 6.436
2.819
2.794
2.770
 O
O
NH2
O
 O4
O6
O1
O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 ARG A:387 A:387 12.0 0.053 G -98.8 -8.9 12.0 0.053 0.0 MA1
GLC
HOH
 6.692
2.994
2.663
 O
O
O
 S4
O6
O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 ARG A:387 A:387 17.0 0.076 G -99.2 -10.2 17.0 0.076 0.0 HOH
 3.065
 NH2
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 ARG A:387 A:387 15.0 0.067 G -95.9 -9.9 15.0 0.067 0.0 EDO
EDO
HOH
 2.894
7.481
2.626
 NH1
C
O
 O2
C2
O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 ARG A:387 A:387 13.0 0.058 G -98.6 -10.1 13.0 0.058 0.0 BGC
GLC
EDO
HOH
 6.597
2.794
2.833
2.694
 O
O
NH2
O
 O4
O6
O1
O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 ARG A:387 P:387 12.0 0.053 G -97.8 -10.9 12.0 0.053 0.0 HOH
 7.320
 CG
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 ARG A:387 A:387 18.0 0.08 G -95.7 -11.5 18.0 0.08 0.0 HOH
 2.821
 O
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 ARG A:387 A:387 14.0 0.062 G -103.1 -7.7 14.0 0.062 0.0 GLC
GLC
HOH
 5.839
2.773
2.927
 C
O
O
 O6
O6
O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 ARG A:387 A:387 19.0 0.084 G -96.0 -9.5 19.0 0.084 0.0 HOH
 2.835
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 ARG A:402 A:402 12.0 0.053 G -92.4 -13.7
af-p19961-f1 1 P19961 98.83 0.0 ARG A:402 A:402 11.0 0.049 G -93.9 -14.9
af-p0dte7-f1 1 P0DTE7 96.87 0.0 ARG A:402 A:402 12.0 0.053 G -94.4 -14.6
af-p0dte8-f1 1 P0DTE8 96.87 0.0 ARG A:402 A:402 11.0 0.049 G -93.7 -15.0
af-p0dub6-f1 1 P0DUB6 96.87 0.0 ARG A:402 A:402 10.0 0.044 G -95.5 -16.8