Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104166839 . G A CCDS783.1:NM_000699.2:c.1342Gac>Aac_NP_000690.1:p.448D>N Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 ASP A:433 A:433 123.0 0.82 S -83.6 21.5 123.0 0.82 0.0 HOH
 8.539
 OD1
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 ASP A:433 A:433 127.0 0.847 S -92.3 33.9 127.0 0.847 0.0 HOH
 2.943
 N
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 ASP A:433 A:433 128.0 0.853 S -91.1 34.1 128.0 0.853 0.0 HOH
 3.140
 N
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 ASP A:433 A:433 125.0 0.833 S -81.3 21.5 125.0 0.833 0.0 HOH
 2.735
 OD2
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ASP A:433 A:433 126.0 0.84 S -87.0 23.2 126.0 0.84 0.0 HOH
 2.770
 OD2
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ASP A:433 A:433 129.0 0.86 S -87.5 26.0 129.0 0.86 0.0 HOH
 4.939
 OD1
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ASP A:433 A:433 125.0 0.833 S -83.2 23.0 125.0 0.833 0.0 HOH
 2.842
 N
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ASP A:433 A:433 127.0 0.847 S -87.1 19.7 127.0 0.847 0.0 HOH
 2.583
 OD2
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ASP A:433 A:433 126.0 0.84 S -85.0 25.4 126.0 0.84 0.0 HOH
 2.932
 N
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ASP A:433 A:433 128.0 0.853 S -85.4 26.2 128.0 0.853 0.0 HOH
 2.945
 N
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ASP A:433 A:433 128.0 0.853 S -82.9 25.9 128.0 0.853 0.0 HOH
 3.058
 N
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ASP A:433 A:433 124.0 0.827 S -87.5 19.5 124.0 0.827 0.0 HOH
 2.363
 OD1
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ASP A:433 A:433 128.0 0.853 S -84.7 27.1 128.0 0.853 0.0 HOH
 2.797
 OD1
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ASP A:433 A:433 127.0 0.847 S -89.8 24.6 127.0 0.847 0.0 HOH
 2.836
 N
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ASP A:433 A:433 125.0 0.833 S -88.0 20.1 125.0 0.833 0.0 HOH
 2.499
 OD2
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ASP A:433 A:433 124.0 0.827 S -87.8 24.4 124.0 0.827 0.0 HOH
 2.590
 OD2
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ASP A:433 A:433 124.0 0.827 S -85.3 16.7 124.0 0.827 0.0 HOH
 2.587
 O
 O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ASP A:433 A:433 128.0 0.853 S -84.3 18.9 128.0 0.853 0.0 HOH
 2.642
 OD2
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ASP A:433 A:433 125.0 0.833 S -84.2 22.1 125.0 0.833 0.0 HOH
 2.622
 OD2
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 ASP A:433 A:433 127.0 0.847 S -92.1 31.7 127.0 0.847 0.0 HOH
 2.600
 OD2
 O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 ASP A:433 A:433 124.0 0.827 S -85.9 35.6 124.0 0.827 0.0 HOH
 2.536
 OD2
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 ASP A:433 A:433 124.0 0.827 S -91.4 11.9 124.0 0.827 0.0 HOH
 2.567
 O
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 ASP A:433 A:433 125.0 0.833 S -87.8 35.3 125.0 0.833 0.0 HOH
 2.142
 H
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 ASP A:433 A:433 124.0 0.827 S -91.5 26.3 124.0 0.827 0.0 HOH
 2.221
 H
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 ASP A:433 A:433 123.0 0.82 S -86.0 26.9 123.0 0.82 0.0 HOH
 2.167
 H
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 ASP A:433 A:433 122.0 0.813 S -93.6 35.7 122.0 0.813 0.0 HOH
 2.904
 N
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 ASP A:433 A:433 124.0 0.827 S -88.6 36.3 124.0 0.827 0.0 HOH
 2.140
 H
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 ASP A:433 A:433 121.0 0.807 S -83.1 23.9 121.0 0.807 0.0 HOH
 2.645
 O
 O
ASP B:433 B:433 116.0 0.773 S -84.2 21.6 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 ASP A:433 A:433 123.0 0.82 S -86.2 26.7 123.0 0.82 0.0 HOH
 2.168
 H
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 ASP A:433 A:433 125.0 0.833 S -88.7 35.7 125.0 0.833 0.0 HOH
 2.215
 H
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ASP A:433 A:433 126.0 0.84 S -89.6 38.2 126.0 0.84 0.0 SO4
HOH
 6.501
2.750
 O
OD2
 O1
O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ASP A:433 A:433 127.0 0.847 S -88.9 42.0 127.0 0.847 0.0 SO4
HOH
 6.144
2.552
 O
OD2
 O4
O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ASP A:433 A:433 129.0 0.86 S -85.1 31.0 129.0 0.86 0.0 SO4
HOH
 5.975
2.709
 O
OD1
 O3
O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ASP A:433 A:433 122.0 0.813 S -86.2 38.5 122.0 0.813 0.0 SO4
HOH
 5.419
2.722
 O
OD1
 O4
O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ASP A:433 A:433 124.0 0.827 S -89.1 38.1 124.0 0.827 0.0 HOH
 3.067
 N
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ASP A:433 A:433 124.0 0.827 S -88.2 24.9 124.0 0.827 0.0 HOH
 2.583
 OD2
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ASP A:433 A:433 125.0 0.833 S -86.7 29.9 125.0 0.833 0.0 HOH
 2.824
 OD2
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ASP A:433 A:433 127.0 0.847 S -88.1 18.4 127.0 0.847 0.0 HOH
 2.640
 OD2
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ASP A:433 A:433 129.0 0.86 S -84.7 18.2 129.0 0.86 0.0 HOH
 2.790
 O
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ASP A:433 A:433 124.0 0.827 S -90.5 28.7 124.0 0.827 0.0 HOH
 2.489
 OD2
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ASP A:433 A:433 124.0 0.827 S -88.9 26.2 124.0 0.827 0.0 HOH
 2.573
 OD2
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ASP A:433 A:433 125.0 0.833 S -85.5 20.5 125.0 0.833 0.0 HOH
 2.957
 N
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ASP A:433 A:433 129.0 0.86 S -85.1 24.7 129.0 0.86 0.0 HOH
 2.901
 OD2
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 ASP A:433 A:433 122.0 0.813 S -87.0 34.1 122.0 0.813 0.0 HOH
 2.259
 H
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ASP A:433 A:433 124.0 0.827 S -90.4 35.3 124.0 0.827 0.0 HOH
 3.060
 N
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 ASP A:433 A:433 123.0 0.82 S -89.9 24.5 123.0 0.82 0.0 HOH
 2.884
 OD2
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 ASP A:433 A:433 128.0 0.853 S -87.6 30.8 128.0 0.853 0.0 HOH
 3.149
 N
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 ASP A:433 A:433 126.0 0.84 S -82.8 26.9 126.0 0.84 0.0 HOH
 5.208
 N
 O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 ASP A:433 A:433 129.0 0.86 S -86.0 26.3 129.0 0.86 0.0 HOH
 2.753
 OD2
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 ASP A:433 A:433 124.0 0.827 S -86.4 26.0 124.0 0.827 0.0 HOH
 5.373
 N
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 ASP A:433 A:433 127.0 0.847 S -87.1 28.6 127.0 0.847 0.0 HOH
 2.959
 N
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 ASP A:433 A:433 127.0 0.847 S -84.4 30.0 127.0 0.847 0.0 HOH
 2.905
 N
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 ASP A:433 A:433 123.0 0.82 S -86.8 29.8 123.0 0.82 0.0 HOH
 3.087
 N
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 ASP A:433 A:433 122.0 0.813 S -92.1 26.1 122.0 0.813 0.0 HOH
 2.948
 N
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 ASP A:433 A:433 113.0 0.753 S -99.3 29.6 113.0 0.753 0.0 HOH
 3.080
 N
 O
ASP B:433 B:433 113.0 0.753 S -99.3 29.6 113.0 0.753 0.0 HOH
 3.080
 N
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 ASP A:433 X:433 125.0 0.833 S -88.3 32.8 125.0 0.833 0.0 HOH
 2.899
 OD1
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 ASP A:433 A:433 123.0 0.82 S -88.1 37.0 123.0 0.82 0.0 HOH
 2.821
 N
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 ASP A:433 X:433 125.0 0.833 S -82.5 30.8 125.0 0.833 0.0 HOH
 2.935
 OD1
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 ASP A:433 A:433 126.0 0.84 S -87.5 28.6 126.0 0.84 0.0 HOH
 2.639
 OD2
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 ASP A:433 A:433 125.0 0.833 S -81.3 27.1 125.0 0.833 0.0 HOH
 2.932
 N
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 ASP A:433 X:433 125.0 0.833 S -85.0 32.4 125.0 0.833 0.0 HOH
 2.598
 OD1
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 ASP A:428 A:428 126.0 0.84 S -94.6 40.0 126.0 0.84 0.0 HOH
 2.594
 OD1
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 ASP A:428 A:428 124.0 0.827 S -86.3 37.6 124.0 0.827 0.0 HOH
 2.857
 N
 O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 ASP A:433 A:433 124.0 0.827 S -91.5 32.7 124.0 0.827 0.0 HOH
 2.687
 OD2
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ASP A:433 A:433 122.0 0.813 S -87.5 32.5 122.0 0.813 0.0 HOH
 2.907
 N
 O
ASP B:433 B:433 124.0 0.827 S -90.5 35.5 NA NA NA
ASP C:433 C:433 127.0 0.847 S -88.1 32.8 NA NA NA
ASP D:433 D:433 120.0 0.8 S -93.2 37.3 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ASP A:433 A:433 129.0 0.86 S -86.8 26.3 129.0 0.86 0.0 HOH
 2.629
 OD2
 O
ASP C:433 C:433 130.0 0.867 S -78.6 14.5 NA NA NA
ASP E:433 E:433 130.0 0.867 S -89.0 33.7 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 ASP A:433 A:433 125.0 0.833 S -91.6 41.5 125.0 0.833 0.0 HOH
 2.749
 OD2
 O
ASP B:433 B:433 125.0 0.833 S -92.1 42.5 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 ASP A:433 A:433 124.0 0.827 S -84.7 34.9 124.0 0.827 0.0 HOH
 1.707
 H
 H1
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 ASP A:433 A:433 117.0 0.78 S -99.1 23.9 117.0 0.78 0.0 HOH
 3.150
 N
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 ASP A:433 A:433 115.0 0.767 S -85.0 27.9 115.0 0.767 0.0 HOH
 3.473
 N
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 ASP A:433 A:433 120.0 0.8 S -91.0 30.4 120.0 0.8 0.0 HOH
 2.221
 H
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 ASP A:433 A:433 123.0 0.82 S -86.8 31.4 123.0 0.82 0.0 HOH
 2.025
 H
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 ASP A:433 A:433 122.0 0.813 S -88.3 35.3 122.0 0.813 0.0 HOH
 2.584
 OD1
 O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 ASP A:433 A:433 122.0 0.813 S -83.9 22.0 122.0 0.813 0.0 HOH
 3.111
 N
 O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 ASP A:433 A:433 127.0 0.847 S -85.2 30.0 127.0 0.847 0.0 HOH
 3.059
 N
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 ASP A:433 A:433 122.0 0.813 S -87.3 35.4 122.0 0.813 0.0 HOH
 2.576
 OD2
 O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 ASP A:433 A:433 127.0 0.847 S -88.9 35.2 127.0 0.847 0.0 HOH
 2.671
 OD2
 O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 ASP A:433 P:433 114.0 0.76 S -95.0 16.5 114.0 0.76 0.0 HOH
 2.908
 OD2
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 ASP A:433 A:433 126.0 0.84 S -80.2 21.2 126.0 0.84 0.0 HOH
 4.860
 O
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 ASP A:433 A:433 118.0 0.787 S -95.3 31.3 118.0 0.787 0.0 HOH
 3.739
 O
 O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 ASP A:433 A:433 125.0 0.833 S -87.6 35.8 125.0 0.833 0.0 HOH
 4.679
 OD1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 ASP A:448 A:448 118.0 0.787 S -87.4 20.5
af-p19961-f1 1 P19961 98.83 0.0 ASP A:448 A:448 117.0 0.78 S -88.7 21.8
af-p0dte7-f1 1 P0DTE7 96.87 0.0 ASP A:448 A:448 116.0 0.773 S -89.6 22.4
af-p0dte8-f1 1 P0DTE8 96.87 0.0 ASP A:448 A:448 117.0 0.78 S -89.3 21.8
af-p0dub6-f1 1 P0DUB6 96.87 0.0 ASP A:448 A:448 117.0 0.78 S -90.0 20.8